- Biotechnology
- Molecular Biology
- Biochemistry
- +۴ مورد دیگر
Dr. Elisabeth Gludovacz is a researcher at the Institute of Animal Cell Technology and Systems Biology , part of the Department of Biotechnology and Food Science at the University of Natural Resources and Life Sciences, Vienna (BOKU). Her work focuses on the structure, function, and therapeutic potential of diamine oxidase (DAO) , a key enzyme in histamine metabolism, and its applications in biopharmaceutical development using Chinese Hamster Ovary (CHO) cell systems . Her research spans enzyme engineering, protein characterization, and metabolic pathway analysis, with a particular emphasis on histamine-related pathologies and the development of histamine-scavenging therapeutics . She has pioneered studies on heparin-binding motifs , glycosylation sites , and N-glycan interactions to optimize DAO's pharmacokinetics and stability. Her team has also contributed to CHO cell line engineering through siRNA screens and recombinase-mediated gene integration strategies. Scientific awards and grants are not explicitly detailed in the provided data. She has supervised presentations at international conferences like the European Congress on Biotechnology and ACIB Science Days , often in collaboration with researchers such as N. Borth and T. Boehm . Her work integrates biochemical assays , molecular modeling , and in vivo studies to address challenges in biopharmaceutical production and metabolic disease .



