جست‌وجوی استاد و پژوهشگر

Dirk P. Bohmannمشاهده پروفایل

استاد

• Molecular Biology
• Genetics
• Signal Transduction
• +۳ مورد دیگر

Dirk P. Bohmann, Ph.D. is a part-time Professor in the Department of Biomedical Genetics at the University of Rochester Medical Center , specializing in Drosophila models to study transcriptional stress responses, aging, and signal transduction pathways. His research focuses on: Nrf2 signaling in oxidative stress and longevity JNK pathway regulation of development and stress tolerance Proteasome dysfunction in aging processes AP-1 transcription factors in cell differentiation Redox regulation of gene expression Protein degradation mechanisms Recent publications highlight his work on anti-aging strategies , neurodegenerative disease models , and genomic stress responses . Scientific accolades include prestigious German Research Foundation and German Cancer Center fellowships. Key awards: German Research Foundation Post-doctoral Fellowship Award (1986-1988) German Cancer Center Predoctoral Fellowship Award (1983-1986) As a leading Drosophila researcher , he has supervised numerous graduate students and mentored significant discoveries in developmental biology and stress response mechanisms. His laboratory investigates: Molecular aging pathways Transcription factor dynamics Proteostasis regulation Stress signaling networks Developmental gene expression Integrative biological modeling

• Pulmonary Systems Biology
• Regenerative Medicine
• Stem Cell Biology
• +۷ مورد دیگر

Herbert Schiller is a Director of the Research Unit for Precision Regenerative Medicine (PRM) at Helmholtz Munich and a Professor for Systems Biology of the Airways and Lungs at the Medical Faculty of Ludwig Maximilian University (LMU) Munich. Previously, he served as Deputy Director of the Institute of Lung Health and Immunity (LHI) and held adjunct faculty positions at the Institute of Lung Health in Giessen, Germany. M.Sc. in Biology and Genetics (University of Vienna, 2004-2008) Ph.D. in Molecular Immunology (Medical University of Vienna, 2008) Postdoctoral training at Max Planck Institute of Biochemistry (2009-2015) His research focuses on extending human healthspan by studying genetic and environmental drivers of chronic lung disease and aging through experimental systems biology and AI-driven approaches. Key areas include: Pulmonary systems biology Regenerative medicine and stem cell biology Extracellular matrix and mechanobiology Single-cell genomics Biology of aging and autoimmune diseases His work emphasizes cross-disciplinary methods like human lung organotypic models and mass spectrometry proteomics. Research trends include lung fibrosis mechanisms, integrin-mediated mechanosensing, and AI applications in chronic disease modeling. Scientific distinctions include: W2 Professorship at LMU Munich Dick Heinegard European Young Investigator Award Helmholtz Young Investigator award German Respiratory Society (DGP) research prize EMBO long term fellowship He has secured research grants from the German Research Foundation (DFG), Chan Zuckerberg Initiative (CZI), and the European Commission. His lab employs cutting-edge single-cell RNA-seq, proteomics, and ex vivo tissue perturbation techniques to elucidate lung disease mechanisms.

Ryoji Amamotoمشاهده پروفایل

استادیار

• Ophthalmology
• Neuroscience
• Molecular Biology
• +۳ مورد دیگر

Ryoji Amamoto, PhD, is an Assistant Professor of Ophthalmology at Harvard Medical School and an Assistant Scientist at Massachusetts Eye and Ear. His research focuses on retinal degeneration, regenerative neuroscience, and RNA sequencing methodologies. Institution: Harvard Medical School (Massachusetts Eye and Ear) Academic Role: Assistant Professor of Ophthalmology Research Interests: Mechanisms of cone photoreceptor survival in Retinitis Pigmentosa Retinoic acid signaling in ocular development Innovative RNA sequencing techniques (Probe-Seq, FIN-Seq) for cell-type-specific analysis Neuronal regeneration and reprogramming in the central nervous system Scientific Contributions: Developed tools for precise transcriptional profiling of injured or diseased tissues Investigated neurotrophic factors in alcohol consumption models Explored regenerative capacity in adult axolotls and mammalian CNS

Matthias Pechmannمشاهده پروفایل

پژوهشگر

• Developmental Biology
• Evolutionary Biology
• Arthropod Evolution
• +۵ مورد دیگر

Dr. Matthias Pechmann is a researcher at the University of Cologne's Biocenter within the Faculty of Mathematics and Natural Sciences, specializing in developmental and evolutionary biology with a primary focus on spider embryology and arthropod evolution. His work investigates the mechanisms of segment and appendage formation in spiders, particularly using the common-house spider ( Parasteatoda tepidariorum ) and the Brazilian white-knee tarantula ( Acanthoscurria geniculata ) as model organisms, with additional research on cricket ( Gryllus bimaculatus ) development. Dr. Pechmann's research centers on understanding the evolutionary success of arthropods through their segmented body plans and articulated appendages. He investigates early embryonic development in spiders, with particular emphasis on the establishment of main body axes, dorsoventral axis patterning, and the genetic mechanisms underlying segment formation. His work combines molecular techniques including RNA interference, gene expression analysis, and comparative approaches to uncover conserved and divergent developmental pathways across arthropods. His most significant contributions involve the role of Ets4 in axis specification and cell migration, Toll genes in axis elongation, and Distal-less as a gap gene during spider segmentation. His publication record demonstrates expertise in developmental genetics and evolutionary biology, with numerous high-impact papers in journals such as eLife, BMC Biology, and Current Biology. His research has significantly advanced understanding of the genetic and cellular mechanisms that govern body plan development in arthropods, particularly revealing how conserved developmental genes have been co-opted for spider-specific morphological features. Dr. Pechmann has received research funding through a University of Cologne Postdoc Grant for his work on dorsoventral axis patterning in crickets, demonstrating his ability to secure competitive research funding. His collaborative approach is evident through extensive co-authorship with researchers across multiple institutions, particularly with Dr. Roth's research group at the University of Cologne as indicated by the website structure (Home > Research > Roth > Pechmann). His laboratory work involves advanced techniques including RNA interference, confocal microscopy, gene expression analysis, and comparative genomic approaches. The research group maintains spider cultures of Parasteatoda tepidariorum and Acanthoscurria geniculata as primary model organisms, with additional work on crickets for comparative studies of dorsoventral patterning.

Fouad Daayfمشاهده پروفایل

استاد

• Molecular Plant-Pathogen Interactions
• Plant Defense Mechanisms
• Biocontrol Strategies
• +۴ مورد دیگر

Dr. Fouad Daayf is a Professor in the Department of Plant Science at the University of Manitoba’s Faculty of Agricultural and Food Sciences. His research focuses on molecular and biochemical interactions between plants and pathogens, including defense suppression mechanisms, biocontrol strategies using plant extracts and beneficial microbes, and detection biology of soilborne/foliar pathogens. Education: PhD in Plant Pathology (Montpellier University, France), Doctorat-d’État in Plant Biotechnology (Cadi Ayyad University, Morocco), MSc in Agronomic Sciences (University of Manitoba), BSc in Plant Biology (Cadi Ayyad University). He teaches courses like PLNT4580 Molecular Plant-Microbe Interactions and PLNT4570 Research Methods in Plant Pathology . His current projects include NSERC-Discovery on pathogen adaptation, S-CAP for potato disease management, and CAP-Barley Cluster for pathogen variation studies. He serves on the Canadian Plant Health Council and chairs the CPS Manitoba Regional Section. Scientific awards include the 2021 Canadian Phytopathological Society Outstanding Research Award and multiple University of Manitoba Merit Awards for research and service. His lab has trained numerous PhD/MSc students and postdocs studying plant defense mechanisms against pathogens like Phytophthora infestans and Verticillium dahliae .

Stéphane Bentolilaمشاهده پروفایل

استاد پژوهشی

• Organelle genetics
• RNA editing
• Cytoplasmic male sterility
• +۲ مورد دیگر

Stéphane Bentolila is an Associate Research Professor in the Department of Molecular Biology and Genetics at Cornell University, affiliated with the Hanson Laboratory and the Graduate Field of Plant Biology. He holds a B.A. in Biochemistry from Université des Sciences et Techniques du Languedoc (Montpellier, France), an M.S. in Agronomic Science from Ecole Nationale Superieure d'Agronomie de Toulouse, and a Ph.D. in Molecular Genetics from Université Claude Bernard - Lyon I. He completed postdoctoral training at Cornell in Steve Tanksley’s laboratory. His research investigates nuclear control of plant organelle gene expression, specializing in organelle genetics, RNA editing, and cytoplasmic male sterility. Key focus areas include the role of pentatricopeptide repeat (PPR) proteins in suppressing mitochondrial defects and characterizing editosome complexes responsible for RNA modifications in chloroplasts and mitochondria. His work integrates quantitative genetics, genomics, and biochemistry to advance RNA engineering in plants. Recent publications demonstrate sustained emphasis on RNA editing mechanisms in Arabidopsis, particularly involving RanBP2-type zinc finger proteins, PPR domains, and RNA recognition motif (RRM) proteins. Trends include structural analyses of editosome components, mitochondrial splicing mechanisms, and implications for respiratory complex biogenesis. No awards, grants, or student advisees are documented in available materials. He leads projects within the Hanson Laboratory, focusing on plant organelle RNA metabolism and collaborative genomics initiatives.

• Molecular Biology
• Virology
• Biochemistry
• +۷ مورد دیگر

Leif Peter Sarin is an Adjunct Professor and University Lecturer in Molecular Biology at the University of Helsinki , affiliated with the Faculty of Biological and Environmental Sciences and Molecular and Integrative Biosciences Research Programme . He leads the RNAcious laboratory and supervises doctoral and Master’s students. Doctor of Philosophy in Molecular Virology (University of Helsinki, 2005-2010) Master of Science in General Microbiology (University of Helsinki, 2005) Title of Docent (Adjunct Professor) in Molecular Biology (University of Helsinki, 2014) His research focuses on post-transcriptional RNA modifications , transfer RNA , translation regulation , and host-pathogen interactions , with applications in synthetic biology and industrial biotechnology . Recent publications explore RNA sequencing methods, tRNA dynamics in marine bacteria, and roles of noncoding RNA in cancer. Scientific awards include the Sigrid Jusélius Fellowship 2012-2014 . Key projects: PROMOTE (2023-) and ProteRNA (2019-2025), funded by the Academy of Finland and Research Council of Finland. He has supervised doctoral and Master’s students, including Matea Radešić and Lampi, M. , and hosted international researchers like Jocelyne DiRuggiero . His work spans virology, biochemistry, and RNA biology, with over 33 publications and 72 collaborative activities.

Hongxin Dongمشاهده پروفایل

استاد

• Alzheimer's Disease
• Cognitive Neuroscience
• Dementia
• +۷ مورد دیگر

Dr. Hongxin Dong is a Professor in the Department of Psychiatry and Behavioral Sciences at Northwestern University's Feinberg School of Medicine, with additional appointments in Neurology through the Ken and Ruth Davee Department. His laboratory has maintained a continuous research program since 2000 focusing on genetic and environmental influences on neurodevelopment and aging, particularly their relevance to Alzheimer's disease and related neuropsychiatric disorders. Dr. Dong holds key affiliations with the Mesulam Center for Cognitive Neurology and Alzheimer's Disease, the Center for Autism and Neurodevelopment, the Northwestern University Clinical and Translational Sciences Institute (NUCATS), the Simpson Querrey Institute for Epigenetics, and the Stephen M. Stahl Center for Psychiatric Neuroscience. His research integrates clinical data from human antemortem assessments and postmortem tissues with animal models to discover novel molecular, genetic, and epigenetic mechanisms underlying neuropsychiatric symptoms in Alzheimer's disease. Dr. Dong's research program is currently supported by multiple NIH grants including R01AG062249 (Molecular Mechanisms Underlying Behavioral and Psychological Symptoms in Alzheimer's Disease), R01AG079989 (Epigenetic Regulation in Aging and Alzheimer's Disease), and R01AG078386 (Estrogen signaling linked to stress and Alzheimer's Disease). His work has established important connections between stress, aging, and Alzheimer's disease pathogenesis, with particular focus on sex differences that may explain women's greater vulnerability to Alzheimer's disease. Dr. Dong serves as Associate Editor for both the American Journal of Neurodegenerative Disease (since 2012) and the Journal of Alzheimer's Disease (since 2010), and previously served as Guest Editor for Neurobiology of Stress (2016-2017). He has received recognition including a Travel Award from the RNA Binding Proteins in Neurological Disease Symposia (2011). His laboratory has produced over 85 publications spanning from 1997 to 2025, with recent work focusing on epigenetic mechanisms in Alzheimer's disease, sex differences in stress responses, behavioral and psychological symptoms of dementia, and novel therapeutic approaches targeting molecular pathways involved in neurodegeneration. His research has significant implications for developing new therapeutic strategies to slow disease onset and prevent progression of Alzheimer's disease and related disorders.

Abdel Rahman Abdel Fattahمشاهده پروفایل

پژوهشگر

• Mechanobiology
• Tissue Engineering
• Extracellular Matrix (ECM) Dynamics
• +۷ مورد دیگر

Abdel Rahman Abdel Fattah is a Principal Investigator at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, Austria. He previously held a postdoctoral position at CeMM (2022–2024) and KU Leuven (Belgium) (2018–2022). Education: BSc and PhD in Mechanical Engineering from McMaster University (Canada) Current Role: Lab Head at CeMM since 2024 Research Interests focus on multiscale mechanobiology, specifically how cells use mechanical forces and extracellular matrix (ECM) dynamics to coordinate tissue organization. His group combines bioengineered mechanical stimulation tools with advanced imaging and computational models to study: Dynamic Cellular and ECM Interactions in health and disease Mechano-Transcriptomic Mapping using spatial transcriptomics and atomic force microscopy (AFM) Computational Modeling of tissue organization via reaction-diffusion systems and positional information theory Disease Applications: Traumatic brain/spinal cord injuries and liver fibrosis Publications highlight interdisciplinary work across mechanobiology, bioengineering, and vascular pathology, with a focus on magnetic actuation, organoid modeling, and ECM dynamics. Articles appear in Nature Communications , Cell Reports , and Lab on a Chip . Recent studies (2024–2025) explore force-mediated vascular lesion growth and transcriptional hallmarks of aging using single-cell analysis. Technological Innovations include: Magnetic Microactuators for local organoid stimulation 3D Soft Microfluidic Systems for perfused tissues Diamagnetophoresis-Based Bioprinting Single-Cell Transcriptomic Atlases for mechanical stress responders

Gregory Smithمشاهده پروفایل

استادیار

• Genetics
• Genomics
• Toxicology
• +۳ مورد دیگر

Gregory Smith is an Assistant Professor at the UNC School of Medicine, Chapel Hill, focusing on genetic and genomic mechanisms of susceptibility to airborne toxicants and lung diseases like asthma and COPD. His research integrates systems genetics approaches with in vivo inhalation exposure models for pollutants such as ozone. Manages Kelada Lab inhalation exposure facility for ozone and e-cigarette aerosols Active in developing novel respiratory phenotyping capabilities Research Interests include environmental genomics, pulmonary toxicology, and systems biology. His work examines how genetic variation influences responses to air pollutants, with applications in personalized environmental health strategies. Recent Publications highlight ozone's impact on lung biology, extracellular vesicle dynamics, and genetic determinants of airway disease. Key collaborative projects involve the Collaborative Cross mouse genetic reference population for studying gene-environment interactions. Contact: gregory.j.smith@unc.edu | Office: 973-459-8881 | Location: 5070E Genetics Medicine Building, Chapel Hill, NC 27599-7264

• Plant Biology
• Microbiology
• Virology
• +۷ مورد دیگر

Jarkko Salojärvi is a University Researcher at the University of Helsinki, affiliated with the Viikki Plant Science Centre (ViPS) and the Organismal and Evolutionary Biology Research Program . He serves as a supervisor in the Doctoral Programme in Plant Sciences and contributes to bioinformatics research for molecular biology and genomics. His research spans plant genomics , evolutionary biology , and bioinformatics , with a focus on silver birch , pathogen interactions , and plant stress responses . Recent work includes genomic analyses of Taphrina infections , betulin biosynthesis in fungi, and adaptive landscapes in forest trees. He has published extensively on plant-microbe interactions , genetic diversity , and computational biology , with funded projects such as TreeBio: Centre of Excellence in Tree Biology and Future Forests . His activities include peer review , conference presentations , and thesis supervision .

• Endocrinology
• Diabetes Research
• Gut Hormones
• +۳ مورد دیگر

Asger Bach Lund serves as a Clinical Associate Professor in the Department of Clinical Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. His institutional address is Blegdamsvej 3, 2200 Copenhagen N, Denmark, affiliated with Region Hovedstaden (Region H) healthcare system. Dr. Lund's research focuses on endocrine physiology with specialization in gut-derived hormones, particularly proglucagon-derived peptides (GLP-1, GIP, GLP-2), their roles in metabolic regulation, and therapeutic applications for diabetes and obesity. His work investigates intestinal hormone expression patterns, amino acid-stimulated secretion dynamics, and molecular mechanisms underlying bariatric surgery outcomes. Analysis of his recent publications reveals dominant research trends in mucosal transcriptomics, pancreatic alpha cell function, and gut-bone axis interactions. His studies frequently employ human physiological models, translational mouse-human comparisons, and advanced molecular techniques to explore metabolic pathways. Lund maintains extensive collaborative networks within Copenhagen's endocrine research community, particularly with the Knop and Holst research groups. His work appears in high-impact journals including Cell Reports Medicine , Gut , and Physiological Reviews , demonstrating significant contributions to metabolic disease research.

Steven L. Salzbergمشاهده پروفایل

استاد

• Computational Biology
• Genomics
• Bioinformatics
• +۴ مورد دیگر

Steven L. Salzberg is the Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science, and Biostatistics at Johns Hopkins University, where he also serves as Director of the Center for Computational Biology. His research focuses on developing computational methods for DNA analysis from next-generation sequencing technologies, with applications across gene finding, genome assembly, comparative genomics, and evolutionary genomics. Dr. Salzberg's research interests center on computational biology and genomics, with particular emphasis on developing innovative software tools for analyzing DNA and RNA sequences. His work has significantly advanced genome assembly techniques, annotation systems, and the understanding of genomic variation. He maintains a strong commitment to data accuracy, as demonstrated by his recent work debunking flawed cancer microbiome research that made headlines in 2023 and 2025 publications. Analysis of his recent publications reveals a consistent trajectory toward increasingly sophisticated genomic analysis tools. His lab has pioneered methods for splice site prediction (Splam), genome annotation (LiftOn), protein-coding region detection (ORFanage), and assembly polishing (JASPER). The research spans computational methodology development while maintaining strong connections to biological discovery and medical applications. Scientific Recognition: His former postdoc Martin Steinegger awarded the 2024 Overton Prize from ISCB Contributed to the landmark publication of the first complete human genome in Science (2022) Dr. Salzberg actively mentors numerous PhD students and postdoctoral fellows, with recent thesis defenses by Kuan-Hao Chao, Markus Sommer, and Ales Varabyou. His lab has secured substantial research funding supporting multiple graduate students and postdocs working on cutting-edge genomic research. The lab maintains extensive collaborations, particularly with Dr. Mihaela Pertea's group, as evidenced by joint publications and shared lab members working on genome assembly and annotation projects. The Salzberg Lab at Johns Hopkins represents a dynamic research environment with continuous growth and evolution. Recent lab news shows consistent expansion with new members joining across multiple years, thesis defenses by key researchers, and high-impact publications spanning Nature, Science, and specialized genomics journals. The lab's collaborative approach with other research groups has resulted in significant contributions to the field of computational genomics.

• Pediatric Oncology
• Neuro-Oncology
• Cancer Genomics
• +۲ مورد دیگر

Professor Steven Clifford is a faculty member at Newcastle University specializing in pediatric neuro-oncology, with primary focus on medulloblastoma—the most common malignant brain tumor in children. His research integrates molecular biology, clinical oncology, and translational medicine to improve therapeutic strategies for childhood brain cancers. His research interests center on molecular subgrouping of medulloblastoma, identification of metabolic vulnerabilities (particularly MYC-driven pathways), and optimization of clinical protocols through multicenter collaborations. Key areas include epigenetic regulation, tumor evolution, and biomarker discovery for precision medicine applications in pediatric patients. Recent publications (2024-2025) demonstrate consistent focus on molecular characterization techniques (bisulfite sequencing, metabolite profiling), clinical trial analysis (HIT 2000, SJMB03), and therapeutic target identification. His work frequently addresses radiotherapy late-effects, surgical outcomes, and consensus treatment guidelines through European research networks. Professor Clifford maintains active collaborations with SIOP-Europe and multiple international institutions, evidenced by co-authorship on large cohort studies involving over 1,100 patients. His research directly informs clinical practice through consensus guidelines and novel diagnostic approaches for molecular subgroup detection.

Wei Sunمشاهده پروفایل

استاد

• Biostatistics
• Computational Biology
• Genomics
• +۵ مورد دیگر

Dr. Wei Sun is a Professor in the Biostatistics Program within the Public Health Sciences Division at Fred Hutchinson Cancer Center, with additional appointments as Member of the Immunotherapy Integrated Research Center (IIRC) and Translational Data Science Integrated Research Center (TDS IRC). He holds affiliated professor positions in Biostatistics at both the University of North Carolina at Chapel Hill and the University of Washington. His educational background includes: PhD in Statistics from University of California at Los Angeles (2007) MS in Statistics from University of California at Los Angeles (2004) BS in Statistics from Peking University, Beijing (2002) Dr. Sun specializes in developing statistical and computational methods for multi-omics data integration, with emphasis on cancer genomics, proteomics, and immunomics. His work pioneers deep learning applications for T cell receptor analysis, HLA typing, neoantigen prediction, and tumor microenvironment characterization using single-cell and spatial transcriptomic technologies. Current research bridges biostatistics with AI-driven cancer diagnostics. His recent publications (2021-2023) demonstrate leadership in cell-type-specific computational frameworks for RNA-seq and spatial omics, with significant contributions to neural network models for immunogenomics and foundational methods for eQTL mapping. Work consistently targets translational applications in tumor heterogeneity and liquid biopsy development. Major recognitions include: Elected Fellow of the American Statistical Association (2017) Junior Faculty Development Award from UNC-Chapel Hill (2010) As Principal Investigator, Dr. Sun leads multiple NIH-funded projects including deep learning for single-cell transcriptomics, statistical methods for gene-phenotype associations using MorPhiC resources, and liquid biopsy consortium coordination for cancer early detection. His grants emphasize cross-institutional collaboration with UW and UNC. He directs the Sun Lab at Fred Hutch—a MorPhiC-affiliated research group focused on creating open-source computational tools for tumor immunology and precision oncology, with active partnerships across the Immunotherapy and Translational Data Science Integrated Research Centers.