RNA structure and function Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۷۳۶-۷۵۰ از ۳٬۹۴۰ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Jay Brito Queridoمشاهده پروفایل

استادیار

University of Michigan-Ann ArborUnited States

Jay Brito Querido, Ph.D. is an Assistant Professor in the Department of Biological Chemistry at the University of Michigan Medical School , with concurrent appointments as a Research Assistant Professor at the Life Sciences Institute and a Faculty Scholar at the Center for RNA Biomedicine . His research focuses on understanding how mRNA translation initiation is regulated in human health and disease, with a special emphasis on DEAD-box helicases using cryo-electron microscopy and biochemical approaches. B.S. , Biochemistry, University of Lisbon (2009) M.S. , Medical Biochemistry, University of Lisbon (2011) Ph.D. , Life and Health Sciences, University of Strasbourg (2017) Postdoctoral Scientist , MRC Laboratory of Molecular Biology (2018-2022) His research explores the structural and functional roles of DEAD-box helicases in translation initiation, including their interactions with ribosomes and regulatory proteins. Recent work demonstrates how cell stress induces selective translational suppression and characterizes tumor suppressor binding in ribosomal subunits. Collaborative studies compare pathogen-mammalian host translation differences for therapeutic targeting. Scientific accolades include: Best M.Sc. Thesis Award from RedTrV Best Ph.D. Thesis Award from Biology Society of Strasbourg FEBS Long-Term Postdoctoral Fellowship Medal of Merit - 1st Class from President of Cabo Verde He is affiliated with the University of Michigan Rogel Cancer Center and contributes to structural biology applications in RNA biomedicine and neuroscience research.

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Ryan S. Grayمشاهده پروفایل

دانشیار

University of Texas at AustinUnited States

Ryan S. Gray, Ph.D. is an Associate Professor in the Department of Pediatrics at The University of Texas at Austin , with an adjunct faculty appointment in the Department of Nutritional Sciences within the College of Natural Sciences . Education: Ph.D. in Cellular and Molecular Biology from UT Austin Postdoctoral Training: Washington University School of Medicine Gray's research focuses on musculoskeletal diseases , particularly adolescent idiopathic scoliosis (AIS) and cartilage degeneration . His lab employs a multi-tiered approach combining zebrafish , mouse , and cell culture models informed by human genomics to uncover mechanisms of spine development and disease. Key areas include: Genetic regulation of spine morphogenesis Role of cilia in cerebrospinal fluid dynamics Protein assembly in vertebrate evolution ADGRG6 and SOX9 signaling in cartilage homeostasis His publications highlight novel genetic pathways in AIS, including Kif6 , Inppl1a , and dysregulated dynein genes . Awards include the Early Investigator Podium Award (2017) and Best Poster Award (2015) from leading orthopedic societies. Gray leads the Gray Lab , which emphasizes translational research for musculoskeletal disorders. The lab's work spans from basic science (e.g., kinesin motor proteins) to clinical applications in scoliosis diagnosis and treatment.

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Seval TÜRKمشاهده پروفایل

استادیار

Antalya Science UniversityTurkey

Seval TÜRK serves as an Assistant Professor in the Department of Basic Sciences at the Faculty of Dentistry, Antalya Science University since 2020. Her research integrates histological, embryological, and tissue engineering approaches with expertise in lectin histochemistry and stem cell applications. Educational background: Bachelor's in Biology, Süleyman Demirel University Faculty of Science and Literature (2008) Master's Degree, Süleyman Demirel University (2008-2010) Ph.D., Süleyman Demirel University (2011-2015) Second Doctorate in Stem Cell and Tissue Engineering, İstinye University (2022-present, thesis stage) Dr. TÜRK's research focuses on structural tissue analysis using advanced histochemical techniques, with significant contributions to gastrointestinal histology, salivary gland pathology, and reproductive tissue dynamics. Her work examines glycoconjugate distributions, endoplasmic reticulum stress mechanisms, and stem cell applications across diverse animal models. Current investigations explore natural compounds' therapeutic potential against diabetic complications and environmental stressors' impacts on organ systems. Analysis of her 2022-2025 publications reveals consistent methodological rigor in lectin histochemistry and immunohistochemistry, with increasing emphasis on stem cell integration. Key thematic clusters include: 1) Chemical compound effects (cinnamic acid, acetyl L-carnitine) on tissue pathology, 2) Electromagnetic field and toxin impacts on cellular structures, and 3) Developmental biology of mammary glands and reproductive tissues. Scientific recognition: No specific awards documented in source materials Dr. TÜRK actively contributes to departmental quality assurance processes and institutional committees. Her extensive publication record indicates successful research project leadership and likely graduate student mentorship, though specific advisee details remain unreported. Current activities include dual institutional engagement between Antalya Science University and İstinye University's stem cell research programs. Her laboratory work centers on histochemical analysis of animal tissue models, particularly rodents and avian species, with recent expansion into stem cell applications through her ongoing doctoral research.

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Pontus Nordenfeltمشاهده پروفایل

دانشیار

Lund UniversitySweden

Pontus Nordenfelt is an Associate Professor and Senior Lecturer at the Department of Infection Medicine (BMC), Lund University. He serves as Principal Investigator for multiple active projects, including InfPathMapper (Horizon Europe) and Broad antibody-based protection against SARS-CoV-2 (Swedish Research Council). His research spans infectious medicine, immunology, cell biology, and biophysics , focusing on human cell-environment interactions in infections and cancer. His lab investigates biomechanical forces, antibody-complement systems, and receptor signaling (Fc receptors, integrins), developing technologies like NETQUANT for quantifying neutrophil extracellular traps. Recent projects include Protumoral lipid droplet-loaded macrophages (Science Translational Medicine, 2024) and Targeting Cholesterol Homeostasis (2024). Pontus has received the Schyberg Award (2018) and Anna-Greta Crafoord Prize (2010). He manages advanced infrastructure including the Nikon Ti2 Pathogen Live Microscope and CytoFLEX flow cytometer , and contributes to UN Sustainable Development Goals in health and innovation.

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Edoardo Sozziمشاهده پروفایل

پژوهشگر ارشد

Lund UniversitySweden

Edoardo Sozzi is a Visiting Research Fellow and PhD student at Lund University's Faculty of Medicine, specializing in the Developmental and Regenerative Neurobiology group under Prof. Malin Parmar. He earned a BSc in Biotechnology (2018) and a dual MSc in Neuroscience (2020) from the University of Pisa and Scuola Normale Superiore, Italy. His research focuses on the development, functionality, and diversity of human dopaminergic neurons using 3D cell culture systems like brain organoids and xenograft models, with heavy reliance on single-cell RNA sequencing. His work intersects neuroscience, developmental biology, and regenerative medicine, targeting neurodegenerative disorders such as Parkinson's disease. Key publication trends include innovations in organoid technology , single-cell transcriptomics , and WNT signaling modulation . He has contributed to 11 scientific outputs , including a 2025 doctoral thesis, peer-reviewed articles in Nature Methods and Development , and a 2023 Horizon Europe grant (OpenMIND project) for opto-electronic neural modeling in neurodegenerative diseases. Sozzi actively participates in academic events, organizing conferences like Neuroscience Day 2024 and UniStem Day 2024 , and serves as a presenter in multidisciplinary initiatives (MultiPark). His work aligns with UN Sustainable Development Goals for Medical and Health Sciences and Neurosciences .

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Hawa Racine Thiamمشاهده پروفایل

استادیار

Stanford UniversityUnited States

Biophysics
Cell Biology
Immunology
+۵ مورد دیگر

Hawa Racine Thiam is an Assistant Professor of Bioengineering and Microbiology & Immunology at Stanford University , where she holds appointments in the Bio-X, Maternal & Child Health Research Institute (MCHRI), and Sarafan ChEM-H. Her research integrates microscopy , microfabrication , and quantitative cell biology to study the cellular biophysics of immune cells , particularly NETosis - a neutrophil-mediated pathogen-trapping mechanism with implications in both infection and sterile inflammation. Ph.D. in Biophysics from Institut Curie/Paris Descartes University (2014) Postdoctoral training in Quantitative Cell Biology at National Institutes of Health (2022) Co-inventor of microfabricated devices for cellular mechanics analysis Her lab's publications reveal trends in nuclear deformation mechanics , cytoskeletal dynamics , and RNA-protein complexes in autoimmunity . Key techniques include high-resolution time-lapse microscopy , mechanical modeling , and microenvironment engineering . Chan Zuckerberg Biohub Investigator (2022-2027) Esther Ehrman Lazard Faculty Scholar (2022-2025) ASCB Porter Prize Honorable Mention (2020) NIH Fellow Award (2019) As a mentor, she serves as Doctoral Dissertation Advisor and Postdoctoral Faculty Sponsor , guiding students in Bioengineering , Biophysics , and Immunology Ph.D. programs. Her work at Stanford's HR Thiam Lab aims to engineer innate immune cells for enhanced host defense while mitigating pathological inflammation through mechanobiological insights.

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Janna Hastingsمشاهده پروفایل

استادیار

University of ZurichSwitzerland

Janna Hastings is Assistant Professor for Medical Knowledge and Decision Support at the Institute for Implementation Science in Health Care (Faculty of Medicine) at the University of Zurich since August 2022, while also serving as Vice-Director of the School of Medicine at the University of St. Gallen. Her research focuses on digitalization in clinical contexts, examining how AI-driven knowledge systems reshape clinical practice, professional identity, and doctor-patient relationships. Education: PhD in Computational Biology (University of Cambridge, 2019), part-time MSc in Computer Science (University of South Africa, 2011), MSc in Philosophy (Open University, 2012) Prior Roles: Group Coordinator at European Bioinformatics Institute (2006-2015), Postdoctoral Researcher at Otto-von-Guericke University Magdeburg (2019-2022), Co-Leader of Human Behaviour-Change Project at University College London (2017-2022) Her research spans ontology development for biomedical domains (ChEBI, Human Behaviour Ontology), AI applications in healthcare decision-making, and behavior change interventions. Key projects include: Building ChEBI molecular ontology Developing Human Behaviour-Change Project knowledge system Ontology-driven mental health frameworks LLM applications in radiation oncology Time-series modeling of metabolism in ageing She explores the capabilities and limitations of clinical AI systems, with publications in JMIR and Lancet Digital Health , covering topics like bias prevention in generative AI and proteomic biomarker discovery. Her work bridges biomedical research with implementation science and digital ethics.

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Jessica Larsenمشاهده پروفایل

دانشیار

Clemson UniversityUnited States

Jessica Larsen is the Carol and John ’63 Cromer Family Endowed Associate Professor in the Department of Chemical and Biomolecular Engineering at Clemson University. She holds a BS (2012) and PhD (2017) in Chemical Engineering from the University of Virginia and Auburn University, respectively. Research Focus: Polymeric biomaterials for blood-brain barrier (BBB) penetration in neurotherapeutics Key Techniques: Enzyme-responsive polymersomes, gene editing delivery, disease-specific stimuli response Disease Targets: Parkinson’s disease, GM1 gangliosidosis, glioblastoma, peripheral nerve injuries Publications highlight advancements in CRISPR-Cas9 delivery MRI contrast agents RNA biology in neural repair Autophagy modulation BBB bypass strategies Awards include: Phil and Mary Bradley Award for Mentoring in Creative Inquiry 2021 Outstanding Faculty Woman at Clemson University NSF CAREER Award (2021) 2022 South Carolina Governor’s Young Scientist Award Advisees include PhD candidates E. Bagwell, M. Shin, N. Henkel, and D. Migliaccio, who contribute to her lab’s work on BBB-targeted therapies. Lab: The Larsen Lab (www.thelarsenlab.com) specializes in nanotherapeutic strategies for central nervous system disorders, with a focus on polymer-based delivery systems.

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Julia Metzgerمشاهده پروفایل

استاد

Max Planck Institute for Molecular GeneticsGermany

Julia Metzger is a Research Group Leader at the Max Planck Institute for Molecular Genetics in Berlin, heading the Heisenberg Research Group Veterinary Functional Genomics . Her group investigates the genetic architecture of mammalian genomes, focusing on non-coding variations and their role in genotype-phenotype relationships , particularly through multi-omics approaches and high-throughput sequencing . Her research integrates computational genomics with experimental biology to study structural variations in pigs and horses, such as body size determination and curly hair phenotypes . Current projects include the Heisenberg-funded MEASURE initiative on regulatory genetics in growth biology. Recent publications highlight her expertise in transcriptome analysis , evolutionary genomics , and veterinary genetics , with co-authorship on studies involving equine , porcine models , and lemur population dynamics . She mentors students like Nima Khaveh (PhD, 2025) and Ward Al Raei (Master’s, 2024), who explore polyploid genomics and tandem repeat genotyping . Awards include the DFG Heisenberg grant .

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Sutapa Chakrabartiمشاهده پروفایل

پژوهشگر

Free University of BerlinGermany

Sutapa Chakrabarti is a Group Leader at the Biochemistry Department, Freie Universität Berlin , focusing on mRNA metabolism and post-transcriptional gene regulation . Her research investigates how cis-acting signals in mRNA interact with protein factors to direct transcripts toward specific degradation pathways , using biochemical and structural approaches . Current Research: Elucidating mechanisms of mRNA decay via Nonsense-Mediated Decay (NMD) , ARE-mRNA decay , and Staufen-mediated decay . Funding: Supported by the German Research Foundation (DFG) and Freie Universität Berlin research commission . Recent Publications: 2025 study on MOV10 helicase in NMD, 2024 analysis of SARS-CoV-2 N protein’s role in mRNA decay, and 2022 work on UPF1-UPF2 interactions.

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Michael Krahnمشاهده پروفایل

استاد

University of MünsterGermany

Michael Krahn is a University Professor at the University of Münster's Faculty of Medicine, where he leads the Medical Cell Biology research group within Medical Clinic D - Internal Medicine. Holding dual doctorates in Veterinary Medicine and Natural Sciences, he maintains an active research program focusing on molecular mechanisms of cell biology with particular emphasis on membrane dynamics and cellular structures. His research interests span biomolecular label chemistry, RNA biochemistry, bioorthogonal chemistry, RNA modifications, nucleic acid chemistry, chemical biology, and mRNA. Professor Krahn's work particularly explores how phosphoinositide lipids regulate cell polarity and membrane organization, with significant contributions to understanding slit diaphragm formation, endocytosis, and related disease mechanisms. His publication record shows consistent research output through 2023, with recent work examining tight junction formation, ER stress responses in podocytes, Hippo pathway regulation, and SEC61A1 variants in liver disease. These publications demonstrate his interdisciplinary approach bridging cell biology, molecular medicine, and disease pathology, primarily using Drosophila models and mammalian cell systems. Professor Krahn participates in the "Cells in Motion" collaborative research initiative and is a member of the Imaging Network, focusing on microscopy applications for cellular dynamics research. His work appears in high-impact journals including Nature Communications, Cell Reports, and Journal of the American Society of Nephrology, reflecting the significance of his contributions to cell polarity and membrane biology fields.

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Guillaume F. Chanfreauمشاهده پروفایل

استاد

University of California, Los AngelesUnited States

Guillaume F. Chanfreau serves as Professor of Biochemistry in the Department of Chemistry and Biochemistry at the University of California, Los Angeles, where his research integrates transcription and post-transcriptional mechanisms to elucidate eukaryotic gene regulation systems. His academic credentials include: BS from University of Lyon & Ecole Normale Supérieure Lyon PhD from University of Paris VI Habilitation from University of Paris XI Human Frontier Science Program Postdoctoral Fellowship at University of California, San Francisco Chanfreau's research centers on RNA biology and gene expression quality control, employing genome-wide approaches to investigate how cells eliminate aberrant RNA species generated during transcription and splicing. His laboratory has pioneered discoveries in RNA degradation pathways, ribosomal protein modification, and the coupling of metal homeostasis to transcriptional machinery, with significant implications for understanding cellular differentiation and disease pathologies. Analysis of his recent publications (2012-2016) reveals consistent focus on RNA processing mechanisms in Saccharomyces cerevisiae, particularly splicing regulation, exonuclease-mediated degradation, and the functional consequences of protein methylation on translation fidelity and ribosome assembly. Key thematic threads connect RNA metabolism to cellular stress responses and metal ion homeostasis. His scientific recognition includes: Human Frontier Science Program Postdoctoral Fellowship Chanfreau has mentored over 15 PhD students including Charles Wang, Jason Gabunilas, and Tad Kawashima, alongside numerous postdoctoral researchers such as Cesar Fernandez and Isabelle Toesca. His laboratory has maintained consistent funding through competitive fellowships and likely NIH/NSF mechanisms supporting his systems biology approach to RNA research, though specific grant details remain unreported in available materials. The Chanfreau laboratory operates as a collaborative research unit within UCLA's biochemistry department, utilizing yeast genetics, genomic techniques, and structural approaches to dissect fundamental mechanisms of gene expression regulation across cellular conditions.

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Frank G. Whitbyمشاهده پروفایل

استاد پژوهشی

University of UtahUnited States

Frank G. Whitby is a Research Professor in the Department of Biochemistry at the University of Utah, where his research centers on high-resolution structural biology and drug discovery. He earned a BS from the University of Denver, a PhD in Biochemistry from Rice University, and pursued postdoctoral training at both the University of Utah and the University of California. His laboratory uses X-ray crystallography to illuminate molecular mechanisms governing viral entry, proteasome function, porphyrin metabolism, and neurotransmission. Education University of Utah – Postdoctoral Fellowship University of California – Postdoctoral Fellowship Rice University – PhD University of Denver – BS Research Interests Whitby’s investigations integrate structural and biochemical approaches to dissect macromolecular machines that underpin human disease. Current foci include: Conformational dynamics of the 20S proteasome and its regulatory complexes Structural determinants of HIV and ebolavirus membrane fusion Mechanistic enzymology of porphyrin biosynthetic enzymes Neuroreceptor regulation and synaptic signaling Structure-guided optimization of small-molecule therapeutics for metabolic and infectious diseases Scientific Contributions & Trends Across more than 50 peer-reviewed publications, Whitby has provided landmark crystal structures for proteasome activators, viral glycoproteins, and metabolic enzymes. His recent work (2021–2024) emphasizes translational applications, revealing how subtle structural changes can be exploited to design potent inhibitors against galactokinase, HIV gp41, and malaria cytochrome c. A consistent theme is the integration of high-resolution structures with functional assays to accelerate therapeutic development. Awards & Recognition Although the supplied text does not enumerate specific awards, Whitby’s sustained funding and prolific publication record in high-impact journals ( Nature , Cell , PNAS , Journal of Biological Chemistry ) underscore his international recognition in structural biology and chemical biology communities. Collaborations & Teams Whitby is a core member of the University of Utah’s Structural Biology Facility and actively collaborates with medicinal chemists, virologists, and neuroscientists worldwide. His multi-disciplinary projects are supported by federal grants and industry partnerships aimed at translating structural insights into novel therapeutics.

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Jennifer E. Creminsمشاهده پروفایل

دانشیار

University of PennsylvaniaUnited States

Jennifer E. Cremins is an Associate Professor and Deans' Distinguished Scholar in Engineering and Medicine at the University of Pennsylvania, with primary appointments in the Department of Bioengineering and secondary appointment in Genetics. She leads the Cremins Laboratory, which works at the spatial biology-technology interface to investigate the structure-function relationship of connections across the scales of chromatin, synapses, and circuits in the developing and diseased mammalian brain. Dr. Cremins' research focuses on understanding how the genome's three-dimensional architecture influences neural development, function, and disease. Her lab has made foundational contributions to elucidating chromatin's higher-order folding patterns at kilobase-resolution during neural lineage commitment, maturation, activity stimulation, and in neurological disorders. The lab's work bridges chromatin folding, synaptic plasticity, and neurophysiology to elucidate how the genome's structure-function relationship influences synaptic defects in neurodevelopmental, neuropsychiatric, and neurodegenerative disorders. Analysis of Dr. Cremins' recent publications reveals a strong focus on the relationship between chromatin architecture and neurological disorders, particularly Alzheimer's disease, fragile X syndrome, and autism spectrum disorders. Her work increasingly integrates computational approaches with experimental techniques to study genome organization at single-cell resolution, with significant emphasis on the role of short tandem repeat expansions in neurodegenerative conditions. Dr. Cremins' laboratory has received significant recognition through numerous scientific awards and fellowships: Deans' Distinguished Scholar in Engineering and Medicine Funding from New York Stem Cell Foundation, Alfred P. Sloan Foundation Support from National Science Foundation, National Institutes of Health (NIMH, NINDS) Grants from Friedreich's Ataxia Research Alliance, Chan Zuckerberg Initiative Funding from Cure Huntington's Disease Initiative, NIH 4D Nucleome Common Fund As an educator and mentor, Dr. Cremins has developed the SEEDS (Summer Exploration in Epigenetics and Data Science) program, a four-year interdisciplinary training program for undergraduates. All 15 graduates of her SEEDs/SEEDs-BRIDGE programs remain in scientific careers, including PhD programs at MIT and UPenn, MD-PhD programs at Mayo, UCSF, and NYU, and MD programs at various institutions. She also develops structured active learning courses focused on statistics, probability, and coding for spatial epigenetics data analysis. The Cremins Laboratory maintains a vibrant research environment with multiple postdoctoral fellows, graduate students, and undergraduate researchers working at the intersection of chromatin biology, neuroscience, and computational genomics. The lab is particularly known for its work on the 4D nucleome and its relationship to neurological disorders, using cutting-edge techniques like Oligopaints imaging and developing computational tools like FISHnet for analyzing chromatin architecture.

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Alex Whiteمشاهده پروفایل

پژوهشگر ارشد

Stanford UniversityUnited States

Alex White is a Research Fellow at Stanford University, currently working in the Deisseroth Lab. He earned his undergraduate degree in electrical engineering from Caltech (2019) and a PhD in electrical engineering from Stanford (2024). His research bridges optics, computation, and neuroscience to develop novel photonic tools for understanding whole-brain connectivity. Education: Caltech (BS 2019), Stanford (PhD 2024) Current affiliation: Deisseroth Lab, Stanford University Expertise: Inverse-designed photonic systems, quantum science, and neural data analysis Alex's work spans classical and quantum photonics, with a focus on inverse design methodologies for nanophotonic devices. His publications highlight innovations in on-chip laser stabilization, nonlinear optical isolators, and structured light applications for high-dimensional quantum communication. Recent research explores photonic crystal microresonator integration for brain connectivity analysis. While not explicitly detailed in the text, Alex's scholarly output demonstrates deep engagement with emerging subfields including: On-chip quantum communication protocols Photonic inverse design optimization Nonlinear optical isolation techniques 3D lensless imaging systems CRISPRi screening methodologies Photonic crystal cavity dynamics

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