جست‌وجوی استاد و پژوهشگر

• Genomics
• Epigenetics
• Systems Biology
• +۷ مورد دیگر

Gary Hon is an Assistant Professor at the University of Texas Southwestern Medical Center (UTSW), jointly affiliated with the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Lyda Hill Department of Bioinformatics. His research lies at the intersection of genomics, epigenetics, and systems biology, with a focus on decoding the regulatory complexity of the human genome. His research interests include: Understanding the molecular basis of cell state for applications in regenerative medicine Elucidating how non-coding genetic variants contribute to development and disease Developing integrative techniques combining gene regulation, epigenetics, genome engineering, and single-cell genomics Advancing bioinformatics tools for analyzing chromatin and transcriptional regulation The trends across his recent publications reveal a strong emphasis on enhancer biology, epigenetic modifications (especially 5mC and 5hmC), single-cell functional genomics, and the development of novel molecular tools such as in situ chromatin capture and combinatorial perturbation assays. His work frequently leverages CRISPR-based technologies and high-throughput sequencing to dissect gene regulatory networks. Dr. Hon has received significant recognition for his innovative research, including: CPRIT Scholar NIH Director’s New Innovator Award Dr. Hon leads the Hon Lab, which actively develops and applies systems-level approaches to study genome regulation. His collaborative research involves advising graduate students and postdoctoral fellows, many of whom appear as co-authors on his publications. While specific grant details are not listed, his prestigious awards suggest substantial federal and state funding support for his high-impact, interdisciplinary research program.

Alireza Ahadiمشاهده پروفایل

مدرس پاره‌وقت

• Data Science
• Machine Learning
• Educational Data Mining
• +۹ مورد دیگر

Dr Alireza Ahadi is a PartTime Lecturer at the Faculty of Engineering & Information Technology , University of Technology Sydney. He holds a PhD in Data Analytics from UTS (2018) and has previously worked as a postdoctoral researcher at Macquarie University (2019-2022) focusing on skills analytics and educational data mining. Education: PhD in Data Analytics (UTS, 2018), Master of Information Technology Extended (UTS, 2013), Bachelor in Computer Science (UTS, 2010). Current Role: Teaching IT and Science subjects at UTS with expertise in databases, programming languages, and data science. Research Interests center on data-driven educational solutions , including text mining in education, skills gap analysis between academia and job markets, code comprehension studies, and miRNA regulation in cancer research. His work integrates machine learning with curriculum analytics to improve educational outcomes and workforce alignment. Recent publications (15 most) reveal trends in applying NLP to educational data, eye-tracking analysis for programming behavior, and skills analytics engines for curriculum-job market mapping. His 2022 article on skills gap identification using Burning Glass data highlights his focus on real-world educational impact. Teaching Experience includes coordination and lecturing in core subjects like Database Fundamentals, Programming Languages, and Data Structures at UTS. He also explores educational data mining , optimization of analytics engines , and recommendation system design in pedagogical contexts.

Tarik Möröyمشاهده پروفایل

استاد پژوهشی

• Molecular Biology
• Immunology
• Hematology
• +۷ مورد دیگر

Dr. Tarik Möröy is a Full Research Professor at the Faculty of Medicine of the Université de Montréal and serves as the President and Scientific Director of the Montreal Clinical Research Institute (IRCM). He is a leading expert in molecular biology, immunology, and cancer research, with over 180 publications, an h-index of 66, and 13,500+ citations. His work focuses on the transcriptional and epigenetic regulation of hematopoiesis and its role in immune system malignancies. Education Ph.D. in Biochemistry, University of Ludwig-Maximilians, Munich (1987) Postdoctoral Researcher, Columbia University, New York (1988–1991) Research Interests Dr. Möröy investigates the molecular mechanisms of immune cell differentiation and leukemogenesis, emphasizing transcription factors (GFI1, GFI1B, c-Myc, Miz-1), RNA helicases (DDX3X), and long non-coding RNAs (lncRNA). His lab combines multiplex flow cytometry, genomics, and computational biology to model hematopoietic malignancies. Publication Trends Recent work explores GFI1/PRMT1 interactions in DNA repair, DDX3X in lymphoid differentiation, and lncRNAs in leukemia. Themes include transcriptional regulation, epigenetic mechanisms, and RNA biology in hematopoietic cancers. Scientific Awards Canada Research Chair (Tier 1) in Hematopoiesis and Immune Cell Differentiation (2007–2021) IRC Medal of Merit for Exceptional Service (2019) Elected member of the Canadian Academy of Health Sciences (2018) Advising and Leadership Dr. Möröy has mentored doctoral students like Marion Lacroix and leads a multidisciplinary team at the IRCM. He has served on national and international scientific advisory boards, including Recherche Canada (President since 2023) and the Canadian Society for Molecular Biosciences (President 2018–2020).

Alice Telesnitskyمشاهده پروفایل

استاد

• Retrovirology
• RNA Biology
• HIV-1 Research
• +۳ مورد دیگر

Alice Telesnitsky is a Professor at the Department of Microbiology and Immunology, University of Michigan Medical School. Her research focuses on HIV-1 RNA biology, including transcription start site heterogeneity, genome packaging, and epigenetic mechanisms of viral persistence. BS in Genetics, University of California, Davis (1979) PhD in Biochemistry, University of California, Berkeley (1988) Postdoctoral fellowship at Columbia University Her work reveals how HIV-1 employs diverse RNA isoforms with distinct functions in replication and pathogenesis. Recent studies highlight RNA structural plasticity, cap-sequestration mechanisms, and transcriptional start site dynamics in viral RNA fate. Collaborated on 20+ publications on HIV-1 replication and RNA structure Led research on transcription start site heterogeneity and its role in viral evolution Co-authored studies on APOBEC3H antiviral activity and UBQLN2 protein toxicity As an MCIDT Affiliate, she investigates HIV-1 genome packaging with collaborators like Michael Summers and James Munro, contributing to understanding HIV therapeutics targets via RNA structural analysis.

Trung Nghia Vuمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۵ مورد دیگر

Trung Nghia Vu is a Principal Researcher at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet in Stockholm, Sweden. His research group focuses on developing and applying statistical and bioinformatics methods for molecular biology and medicine, with particular emphasis on cancer genomics and pharmacogenomics. Dr. Vu received his PhD from the Department of Mathematics and Computer Science at the University of Antwerp, Belgium (2009-2014), following an MSc in Computer Engineering from Korea Aerospace University (2006-2008) and a BSc in Technology from Vietnam National University in Hanoi (2000-2004). His research focuses on developing statistical and bioinformatics methodologies for analyzing high-throughput omics data, with specific interests in single-cell sequencing analysis, characterization of cancer omics, and pharmacogenomics. His group has developed 20 statistical and bioinformatics tools available through Biostat Wiki Primary research areas include gene/isoform quantification, detection of abnormal RNAs, single-cell RNA-seq analysis, and drug response prediction Current projects focus on breast cancer and Acute Myeloid Leukemia (AML) Analysis of Dr. Vu's recent publications reveals a strong focus on cancer genomics, particularly in AML and breast cancer. His work bridges computational biology with clinical applications, developing methods for spatial transcriptomics, drug synergy prediction, and circular RNA analysis. The research demonstrates a clear trajectory toward precision medicine applications, with increasing emphasis on personalized drug response prediction and pathway activation modeling. Dr. Vu actively supervises multiple students and researchers, including both completed PhD students (Quang Thinh Trac, Lu Pan, Wenjiang Deng) and ongoing supervisees (Gulser Caliskan, Meghana Alugunoolla, Yuying Li, Aron Arzoomand). His research is supported by significant grants from the Swedish Research Council, CancerFonden, and Karolinska Institutet. He leads the Computational Medicine and Bioinformatics research group at Karolinska Institutet, which collaborates with international clinical and systems-biology researchers. The group maintains active development of bioinformatics tools and maintains the Biostat Wiki platform for academic use. Dr. Vu also contributes to teaching through master's and doctoral courses in biostatistics and R programming at Karolinska Institutet.

• Food Science
• Microbiology
• Biochemistry
• +۳ مورد دیگر

Maria Leticia Miranda Fernandes is a Researcher at the Polytechnic Institute of Bragança , with a focus on food science, microbiology, and biochemical characterization of beekeeping by-products. Her work spans 30 years and includes 283 publications , with extensive collaborations across Brazil and Portugal. Research Interests Food safety and microbiology Antioxidant and antimicrobial mechanisms Chemical profiling of natural products High-pressure food processing Stingless bee product applications Pharmacological evaluation of plant extracts Scientific Awards Highly Cited Researcher (Cross-Field) - Web of Science (2018-2023) Stanford University Top 2% Scientists (2020-2023) Multiple 'Prémio Inventor' awards from CINOVA/UFRB (2015, 2019) Best Poster Awards (2010, 2013) Her research has been supported by grants from Fundação para a Ciência e Tecnologia (FCT) and institutional partnerships with Brazilian universities. She leads studies on mead production, propolis applications, and foodborne pathogen control.

Domenico Praticòمشاهده پروفایل

استاد

• Clinical Pharmacology
• Oxidative Biology
• Alzheimer's Disease
• +۴ مورد دیگر

Domenico Praticò, MD, FCPP is a Professor in the Department of Neural Sciences at Lewis Katz School of Medicine, Temple University, and the Founding Director of the Alzheimer's Center at Temple. His research focuses on clinical pharmacology, oxidative biology, and neurodegeneration. MD, University of Rome "La Sapienza" (1986) Internship, Residency, and Fellowship at University of Rome "La Sapienza" Cardiovascular Science Fellowship, University of Dublin (1994) Dr. Praticò investigates the role of bioactive oxidized lipids, oxidative stress, and neuroinflammation in aging, Alzheimer's disease, and cardiovascular disorders. His lab employs cellular and animal models to translate findings into human disease understanding. Recent publications highlight his work on Alzheimer's disease mechanisms involving non-coding RNAs, endosomal trafficking, lipid metabolism, autophagy, and vascular contributions. His studies bridge neurobiology, cardiovascular research, and translational medicine. Fellow of the Center for Clinical Pharmacology (FCPP) His lab integrates in vitro systems and transgenic mouse models to study APP processing, Aβ metabolism, tau pathology, and synaptic dysfunction. The Pratico Lab emphasizes drug discovery for neurotherapeutics and biomarker identification.

Darrell R. Davisمشاهده پروفایل

استاد

• RNA Biology
• Antiviral Therapeutics
• Virology
• +۳ مورد دیگر

Darrell R. Davis serves as Professor of Medicinal Chemistry and Adjunct Professor of Biochemistry at the University of Utah, with primary affiliation in the Department of Medicinal Chemistry and active roles in the Molecular Biology and Biological Chemistry Programs. His educational credentials include a B.S. from the University of Puget Sound and a Ph.D. from the University of Utah, establishing deep institutional roots. Research focuses on RNA structure-function relationships in viral pathogenesis, specifically developing host-targeted antivirals that disrupt viral mRNA translation mechanisms across diverse pathogens including SARS-CoV-2, HCV, and Zika virus. Laboratory work has identified enantiomerically specific compounds like DD011-E2 (EC 50 = 140 nM against SARS-CoV-2) with conserved activity against phylogenetically distant viruses, indicating a novel mechanism targeting cellular processes. Publication analysis reveals consistent emphasis on RNA structural biology applied to antiviral discovery, spanning fundamental tRNA/HIV-1 interactions to translational control elements in HCV IRES. Methodologies integrate molecular dynamics simulations, NMR spectroscopy, and cell-based antiviral assays across all studies, demonstrating interdisciplinary rigor in targeting RNA for therapeutic intervention. No scientific awards are documented in the source material. Dr. Davis leads an active research laboratory (accessible via Lab Page link) with extensive collaborative networks evident in co-authorship patterns, though specific grant details remain unreported. He mentors graduate students in medicinal chemistry and virology, contributing to both the Biological Chemistry and Molecular Biology Ph.D. programs through curriculum development and research supervision. Laboratory infrastructure supports RNA structural analysis and antiviral screening, with current work optimizing lead compounds against pandemic-capable viruses through mechanistic elucidation of host-targeted inhibition pathways.

Anthea Letsouمشاهده پروفایل

استاد

• Developmental Biology
• Neurogenetics
• Molecular Genetics
• +۵ مورد دیگر

Anthea Letsou is a Professor of Human Genetics at the University of Utah, with a research focus on using Drosophila melanogaster to model human developmental and neurodegenerative diseases. Her work spans two primary areas: embryonic morphogenesis and neurometabolic disorders. Education: B.A., Harvard University; Ph.D., Yale University Research Interests: Dr. Letsou’s laboratory investigates the molecular mechanisms underlying dorsal closure during embryonic development, focusing on evolutionarily conserved pathways like JNK and Dpp signaling. She also develops Drosophila models for Adrenoleukodystrophy (ALD), a fatal neurodegenerative disorder caused by VLCFA accumulation, aiming to elucidate disease etiology and identify therapeutic targets. Publication Trends: Her research integrates genetic, biochemical, and pharmacological approaches in Drosophila , emphasizing conserved mechanisms relevant to human health. Key themes include signal transduction pathways, epithelial morphogenesis, lipid metabolism, and neurodegeneration. Lab Activities: Dr. Letsou’s lab employs double mutant studies to explore gene redundancy in VLCFA metabolism, characterizes dorsal closure dynamics, and screens for neuroprotective drugs using Drosophila models.

Koushik Royمشاهده پروفایل

استادیار

• Immunological Memory
• Protein Design
• Vaccine Development
• +۶ مورد دیگر

Koushik Roy is an Assistant Professor of Microbiology & Immunology at the University of Utah School of Medicine , specializing in B cell fate decisions, immunological memory, and vaccine development. His research bridges molecular biology, systems immunology, and chemical biology to address fundamental and translational challenges in infectious diseases and cancer. Education: M.S., Jadavpur University Ph.D., CSIR-Indian Institute of Chemical Biology Postdoctoral Research, University of California, Los Angeles Research Focus: Dr. Roy's lab investigates the molecular mechanisms governing B cell differentiation into plasma cells and memory B cells, particularly how pathogens disrupt these processes. His work combines systems biology (omics, microscopy, mathematical modeling) and chemical biology (peptide design) to develop therapeutic strategies for B cell lymphomas and vaccines against infectious diseases. Key Projects: 1. NFkB signaling in B cell fate: Deciphering how NFkB dynamics regulate proliferation-differentiation transitions. 2. Quantitative B cell responses: Modeling immune dysregulation in infectious diseases. 3. Peptide-based immunomodulators: Engineering synthetic peptides for vaccine enhancement and cancer therapy. Scientific Recognition: F1000 Faculty Recommended - New Finding (2019) F1000 Faculty Recommended - Interesting Hypothesis (2013, 2016) Laboratory Philosophy: Emphasizes rational thinking, open feedback, self-criticism, diversity, and mental health awareness in scientific mentorship.

• Cancer Biology
• Epigenetics
• Glioblastoma
• +۳ مورد دیگر

William Alexander Flavahan is an Assistant Professor at UMass Chan Medical School, affiliated with the T.H. Chan School of Medicine and the Morningside Graduate School of Biomedical Sciences. His primary department is Molecular, Cell and Cancer Biology, with additional appointments in Systems Biology, Biochemistry and Molecular Biotechnology, Cancer Biology, and translational science programs. He holds a BE in Biomedical Engineering and a PhD in Molecular Medicine, both from Case Western Reserve University. Dr. Flavahan's research focuses on epigenetic plasticity, tumorigenesis, and the role of cancer stem cells in therapeutic resistance. His work investigates chromatin remodeling, insulator dysfunction in gliomas, metabolic adaptations in tumor microenvironments, and the interplay between epigenetic dysregulation and oncogene activation. Key areas include glioblastoma biology, cancer metabolism, and developing strategies to overcome treatment resistance. His publications demonstrate a consistent focus on epigenetic mechanisms in cancer, particularly glioblastoma and gastrointestinal stromal tumors. Recent work explores metabolic dependencies of tumor-initiating cells, chromatin topology alterations in SDH-deficient cancers, and RNA metabolism in radiation resistance. The research integrates genomics, epigenetics, and cancer biology to identify novel therapeutic vulnerabilities. Dr. Flavahan collaborates extensively within cancer biology networks, co-authoring with researchers specializing in epigenetics, stem cell biology, and neuro-oncology. His work involves studying tumor microenvironments, myeloid-derived suppressor cells, and chromatin remodeling complexes.

Webster H. Pilcherمشاهده پروفایل

استاد

• Neurosurgery
• Epilepsy
• Brain Tumors
• +۷ مورد دیگر

Dr. Webster H. Pilcher is a Professor and Chair of Neurosurgery at the University of Rochester Medical Center (URMC), where he holds the Ernest & Thelma Del Monte Distinguished Professorship in Neuromedicine. He completed his MD/PhD in Neuroscience/Anatomy at URMC, trained in neurological surgery at Rochester, and pursued epilepsy/brain tumor research at the University of Washington. Education: MD/PhD, University of Rochester School of Medicine/Dentistry (Neuroscience/Anatomy) Undergraduate, Colgate University Dr. Pilcher specializes in epilepsy surgery, brain/spinal tumors, and neurodegenerative diseases. His research includes brain mapping , neurosurgical oncology , and cost-effective care models . Recent publications focus on single-cell genomics , mobile stroke units , and functional connectivity studies . Scientific Awards: Merit Award (2008) Upjohn Surgical Research Award (1987) Resident Research Award (1986) Alpha Omega Alpha (1983) As a clinician-scientist, Dr. Pilcher expanded URMC Neurosurgery to national prominence with $7.9M+ annual funding. He leads the Rochester Neurosurgery Partners initiative and resides in Honeoye Falls, NY, with his family.

Mani S. Mahadevanمشاهده پروفایل

استاد

• Human genetics
• Molecular genetics
• Myotonic dystrophy
• +۴ مورد دیگر

Mani S. Mahadevan, M.D. is a Professor of Pathology at the University of Virginia School of Medicine, where he directs a prominent research program focused on the molecular genetics of myotonic dystrophy (DM), the most common inherited neuromuscular disorder in adults. His work has established fundamental understanding of the disease mechanisms and continues to drive therapeutic development. Dr. Mahadevan received his medical degree from the University of Ottawa in 1986, followed by clinical training including an internship at Victoria Hospital in London, Ontario (1986-1987), residency at the University of Ottawa (1987-1991), and a research fellowship at the Children's Hospital of Eastern Ontario (1991-1995). This comprehensive background bridges clinical medicine with deep molecular investigation. His laboratory made seminal contributions to the field by cloning the DM gene and identifying the mutation as a CTG trinucleotide repeat expansion in the 3' untranslated region of the DMPK gene. Current research focuses on RNA-protein interactions, muscle regeneration in RNA toxicity models, and identifying therapeutic targets. His team has demonstrated that mutant DMPK 3'UTR mRNA forms distinct nuclear foci and inhibits normal muscle differentiation, establishing critical disease mechanisms. Analysis of Dr. Mahadevan's publication record reveals a consistent trajectory from fundamental gene discovery to sophisticated investigations of RNA toxicity mechanisms and therapeutic development. His recent work shows particular emphasis on muscle regeneration pathways, novel therapeutic targets like the TWEAK/Fn14 pathway, and the role of RNA-binding proteins in disease pathology. This evolution reflects both maturation of the field and strategic research direction. Dr. Mahadevan has established a productive research program that has generated significant insights into myotonic dystrophy pathogenesis. His laboratory has developed important cellular and animal models that serve as platforms for therapeutic testing. Through his mentorship and collaborative efforts, he has contributed to training researchers in neuromuscular disorders, with his work continuing to shape our understanding of molecular mechanisms underlying this complex disorder.

Jeffrey K. Mooreمشاهده پروفایل

دانشیار

• Microtubule networks
• Cell biology
• Molecular motors
• +۷ مورد دیگر

Jeffrey K. Moore is an Associate Professor in the Department of Cell and Developmental Biology at the University of Colorado Anschutz Medical Campus. He also serves as the Director of the Graduate Program in Cell Biology, Stem Cells and Development. His research focuses on understanding how microtubule networks organize cells and regulate crucial cellular processes, with implications for human diseases including cancer and neuropathies. Dr. Moore received his Ph.D. from the University of Rochester in 2006. His academic journey has led him to specialize in cellular organization mechanisms, particularly how the microtubule cytoskeleton controls organelle positioning during cell division and migration. His work bridges fundamental cell biology with potential clinical applications. Dr. Moore's research interests center on the molecular mechanisms that regulate microtubule dynamics and function. His laboratory investigates how molecular motors interact with microtubule tracks, how mitosis is coordinated with cell polarity during asymmetric cell divisions, and how cells develop resistance to microtubule-targeting cancer drugs. His work combines powerful yeast genetics with quantitative microscopy and protein biochemistry to uncover fundamental principles of cellular organization. The laboratory's research has significant implications for understanding human diseases where microtubule dysfunction plays a critical role. Dr. Moore's publications reveal how specialized microtubules serve different cellular functions through tubulin isotypes and post-translational modifications. His work on the 'tubulin code' has advanced understanding of how microtubule networks can be differentially regulated in various cellular contexts. Recent publications examine α-tubulin regulation, tubulin isotype specialization, and the role of microtubule-based forces in genome stability. As Director of the Graduate Program in Cell Biology, Stem Cells and Development, Dr. Moore mentors numerous graduate students in the Department of Cell and Developmental Biology. His research program is supported by grants from the National Institutes of Health and other funding agencies focused on understanding fundamental cellular processes with implications for human health. The Moore Lab at the University of Colorado Anschutz Medical Campus utilizes the budding yeast Saccharomyces cerevisiae as a primary model system. The lab brings together researchers with expertise in genetics, cell biology, biochemistry, and quantitative imaging to tackle questions about cellular organization. Their collaborative approach has led to important insights into how cells manipulate their internal architecture for proper function, with findings relevant to understanding disease mechanisms and potential therapeutic approaches.

Yi Panمشاهده پروفایل

استاد

• Parallel and Cloud Computing
• Wireless Networks
• Bioinformatics
• +۳ مورد دیگر

Dr. Yi Pan is a Distinguished University Professor and Chair of the Department of Computer Science at Georgia State University. He holds a B.Eng. and M.Eng. from Tsinghua University (China) and a Ph.D. from the University of Pittsburgh (USA). His research focuses on parallel computing, wireless networks, bioinformatics, and machine learning, with over 330 publications and 39 authored/edited books. Dr. Pan has organized international conferences and delivered over 40 keynote speeches globally. Education: B.Eng., Computer Engineering, Tsinghua University, 1982 M.Eng., Computer Engineering, Tsinghua University, 1984 Ph.D., Computer Science, University of Pittsburgh, 1991 Research Interests: Dr. Pan’s work spans parallel and cloud computing, wireless networks, and bioinformatics. His contributions include scalable algorithms for functional module discovery in protein networks, self-defense mechanisms for cyber threats, and efficient routing protocols for sensor networks. Recent efforts integrate AI into healthcare, such as lesion localization in OCT imaging and autism spectrum disorder diagnosis via EEG analysis. Awards & Recognition: IEEE Distinguished Speaker (2000–2002) Yamacraw Distinguished Speaker (2002) Listed in Who’s Who in America and Who’s Who in Computational Science Awards from NSF, AFOSR, IBM, and Mellon Foundation Advising & Leadership: As department chair, Dr. Pan oversees interdisciplinary collaborations between Computer Science and Computer Information Systems. He has advised numerous students and holds editorial roles in 15 journals, including several IEEE Transactions. His grants focus on advancing AI-driven healthcare, cybersecurity, and computational biology. Labs & Teams: Leads research initiatives in bioinformatics, medical AI, and parallel computing, collaborating with industry partners like IBM and Shell Oil. Active in organizing conferences such as the IEEE International Conference on Bioinformatics and Biomedicine.