RNA processing Professors and Supervisors in Austria

Maria Carmo-Fonsecaمشاهده پروفایل

استاد

Graz University of TechnologyAustria

Maria Carmo-Fonseca is a Full Professor at the University of Lisbon Medical School and President of Instituto de Medicina Molecular João Lobo Antunes since 2014. She has held leadership roles including Executive Director of Instituto de Medicina Molecular (2001-2014) and Director of the Harvard Medical School-Portugal Program (2009-2015). She chairs the Scientific Advisory Board for GenoMed, a molecular diagnostics spin-off. PhD from Instituto Gulbenkian de Ciência (1988) Post-doctoral fellow at European Molecular Biology Laboratory (1992) Editor: Journal of Cell Science and RNA journal Member: European Molecular Biology Organization, Academia das Ciências de Lisboa, Academia Portuguesa de Medicina Her research focuses on pre-mRNA splicing mechanisms and RNA metabolism in disease. Using technologies like NET-seq and POINT, her work bridges transcription dynamics, spliceosome interactions, and therapeutic applications in cancer and monogenic disorders. Her publications (150+ papers, h-index 54) emphasize RNA processing as a diagnostic and therapeutic target. Recent articles highlight innovations in nascent RNA analysis, transcription-splicing coupling, and antisense RNA regulation. These span subfields including RNA sequencing, spliceosome inhibition, and age-related barriers to stem cell reprogramming. RNA Society President (2021-2022) Prémio Pessoa (2010) Gulbenkian Science Award (2007) José Sala-Trepat Prize (1993) With 10,000+ citations, she leads a lab advancing RNA biology through genome-wide studies and collaborates with international organizations. Her work integrates basic science with clinical translation in molecular diagnostics and drug development.

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Peter Holubarمشاهده پروفایل

دانشیار

University of Natural Resources and Life Sciences ViennaAustria

Peter Holubar serves as an Associate Professor at the University of Natural Resources and Life Sciences, Vienna (BOKU), primarily affiliated with the Office of the Works Council for Academic Staff. He holds a Habilitation in Applied Microbiology (2003) and an MBA, with career milestones including Key Researcher for Biogas at Competence Center Bioenergy 2020+ (2010-2011) and Deputy Chairman of the Senate (2003-2006). His research focuses on bioprocess engineering, environmental biotechnology, and renewable energy systems, with specialization in anaerobic digestion optimization, biogas production, and sustainable biomass conversion. Key areas include microbial community dynamics in hydrocarbon degradation, life cycle assessment of bioenergy systems, and development of control strategies for fermentation processes. Publications demonstrate consistent focus on sustainable energy solutions, with recent work emphasizing microbial ecology in bioremediation and methodological advances in RNA extraction from complex biocoenoses. Earlier contributions established frameworks for environmental impact assessment of biomass-to-energy pathways. He has supervised 38+ graduate theses spanning microbial fuel cells, wastewater treatment, and fermentation technology. Grant leadership includes EU projects like CROPGEN (renewable energy from crops) and AMONCO (biogas process control). Administrative service includes Senate leadership and ongoing roles in academic governance through the Works Council. Professional memberships encompass DWA (German Water Association) and editorial duties for multiple journals including Water Research and Environmental Science & Technology .

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Nicole Borthمشاهده پروفایل

دانشیار

University of Natural Resources and Life Sciences ViennaAustria

Nicole Borth is Associate Professor (associate Univ.Prof.) at the University of Natural Resources and Life Sciences, Vienna (BOKU) and Deputy Head of the Institute of Animal Cell Technology and Systems Biology . Her work sits at the intersection of cell engineering, systems biology and biopharmaceutical manufacturing, with CHO and HEK293 cells as primary platforms. Research in a nutshell: Genome-wide CRISPR/Cas deletion and activation screens to map essential loci and boost recombinant protein titres. Epigenetic and synthetic-biology toolboxes (dCas9-DNMT, synthetic promoters, RNA devices) for multiplexed gene-control. Glyco-engineering and biomarker discovery to optimise critical quality attributes of monoclonal antibodies. Low-cost, animal-component-free media design and microfluidic single-cell cloning to shorten development timelines. Between 2022-2025 her group released a rapid succession of papers exploiting nanopore Cas9-targeted sequencing to pinpoint transgene integration sites, unveiled novel stress-biomarkers for difficult-to-express mAbs, and provided public-domain glyco-analytics for the NIST CHO reference line. Parallel projects apply similar tool-chains to AAV production in HEK293 and characterise human diamine oxidase biopharmaceuticals. Awards & funding: Specific prizes not enumerated in supplied text; however, the volume and recency of high-impact publications indicate sustained competitive funding. Contact: nicole.borth@boku.ac.at | Tel +43 1 47654-79064 | Muthgasse 11, 1190 Vienna, Austria.

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Gerald Striednerمشاهده پروفایل

استاد

University of Natural Resources and Life Sciences ViennaAustria

Gerald Striedner serves as Professor and Head of the Institute of Bioprocess Science and Engineering at the University of Natural Resources and Life Sciences, Vienna (BOKU). He leads a comprehensive research group focused on upstream process development for the production of recombinant proteins, plasmid DNA, and virus-like particles using bacterial, insect, and mammalian cell systems. His research interests span advanced process characterization , E. coli expression system design , rational bioprocess development , process monitoring and control , continuous biomanufacturing , and synthetic biology applications . His work integrates PAT/QbD concepts to create efficient production platforms for bio-pharmaceutical, industrial, and environmental applications. Analysis of his recent publications reveals a strong focus on cutting-edge bioprocess technologies including non-canonical amino acid incorporation, advanced protein purification methods, continuous manufacturing platforms, and enzyme engineering for polymer degradation. His research demonstrates a consistent emphasis on both fundamental process understanding and practical applications for industrial biotechnology. As an academic leader, Professor Striedner supervises a diverse team including PhD students, postdocs, and senior scientists. His research group maintains active collaborations with academic partners across Europe, including institutions in Austria, Portugal, and Germany, reflecting the international scope of his work. His laboratory operates within BOKU's Institute of Bioprocess Science and Engineering, which features advanced pilot plant facilities for training and research purposes, providing an integrated environment for both fundamental research and practical application development in bioprocess engineering.

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Ovidiu Paunمشاهده پروفایل

دانشیار

University of ViennaAustria

Assoc. Prof. Ovidiu Paun is an Associate Professor at the Department of Botany and Biodiversity Research within the Faculty of Life Sciences at the University of Vienna, Austria, where he has served since 2019 following a tenure-track Assistant Professor position (2015-2019). He leads the Plant Ecological Genomics research group, focusing on understanding why and how organisms diversify through fundamental evolutionary processes of adaptation and divergence. Paun earned his PhD in Evolutionary Biology from the University of Vienna (2005), with a dissertation on "Evolution of apomixis in the Ranunculus cassubicus group," supervised by Elvira Hörandl and Tod Stuessy. Prior to this, he completed a degree in Horticulture from the University of Agronomical Sciences in Bucharest, Romania (2000). His postdoctoral training included prestigious Marie Curie and Erwin Schrödinger Fellowships at Royal Botanic Gardens Kew (2006-2010). His research integrates molecular data with environmental context to investigate natural populations of both model and non-model organisms, exploring the origin of biodiversity and its dynamics. With particular interest in understanding the role of the environment in evolutionary processes, Paun has made significant contributions to the exploration of epigenetic variation in evolution. His integrative approaches, built upon a genomics core, aim to understand how lineages speciate and spread across niches, including novel environments. Analysis of Paun's recent publications reveals a strong focus on polyploidy, adaptation mechanisms, and speciation processes across diverse plant systems. His work spans from orchids (Dactylorhiza) to bromeliads (Tillandsia), examining parallel adaptation, epigenetic contributions to evolution, and the genomic basis of ecological divergence. A recurring theme is the investigation of how environmental factors shape evolutionary trajectories through both genetic and epigenetic mechanisms. 2013 START Prize from the Austrian Science Fund (FWF) 2009 Elected fellow of the Linnean Society, London 2007 Marie Curie Fellowship from the EU Commission 2006 Erwin Schrödinger Fellowship from the Austrian Science Fund (FWF) 2006 Best Presentation Award from the Systematics Association 2002 IAPT Award for young investigators in Plant Systematics Paun has secured substantial research funding including an FWF Stand-alone grant (P35275-B, 2022-2026, €600K), multiple Marie Curie Intra-European Grants (2022-2024, €359K total), and a prestigious START grant (Y661, 2013-2022, €1.2M). He serves as a reviewer for numerous funding agencies including ERC, NSF, and DFG, and has organized international symposia on evolutionary epigenetics and speciation genomics. His laboratory employs integrative genomic approaches to investigate adaptation mechanisms and speciation processes, with particular emphasis on how organisms respond to environmental challenges and how this shapes biodiversity patterns.

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Manuela Baccariniمشاهده پروفایل

استاد

University of ViennaAustria

Manuela Baccarini is a Professor at the University of Vienna and serves as Vice Rector within the Rectorate. She is affiliated with the Department of Microbiology, Immunobiology and Genetics, where her research focuses on RAF kinase signaling, cell proliferation, and molecular mechanisms in cancer and inflammatory responses. Her recent work explores autophagy, lysosomal trafficking, and signal transduction dynamics. Email: manuela.baccarini@univie.ac.at Research Areas: RAF kinase, cell signaling, cancer biology, autophagy, inflammation Recent Research Trends: Her publications from 2018–2025 highlight RAF kinase's role in autophagic lysosome reformation, inflammatory gene regulation via RNA decay, endothelial cell mechanics, and metabolic targeting in tumors. The work spans cancer biology, immunology, and molecular genetics. Teaching: She supervises seminars in the Vienna Biocenter PhD Program and courses on cellular architecture and maintenance.

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Laura de Rooijمشاهده پروفایل

پژوهشگر

University of ViennaAustria

Laura de Rooij is a Principal Investigator at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences since September 2022. Her research combines single-cell omics with functional vascular assays to characterize endothelial cell heterogeneity in health, aging, and disease contexts. University of Amsterdam - Biomedical Sciences graduate McMaster University - RNA-binding protein research in leukemia VIB-KU Leuven - Postdoctoral work in angiogenesis and vascular metabolism CeMM - Lab leader since 2022 Research focus areas: Endothelial cell aging mechanisms across organs Disease-associated vascular rewiring in conditions like COVID-19 and cancer Development of 3D culture systems including vessel-on-chip platforms CRISPR-based functional interrogation of molecular circuitries in endothelial dysfunction Key publications highlight: Characterization of lipid-processing endothelial subtypes in breast cancer Identification of profibrotic endothelial phenotypes in pulmonary fibrosis Advances in single-cell transcriptome atlases across tissues Development of organotypic human endothelial models using iPSCs Laboratory resources: Lab website maintaining research continuity 3D culture platforms for EC functional analysis Collaborative networks across European research institutes

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Stefan Kubicekمشاهده پروفایل

پژوهشگر

University of ViennaAustria

Stefan Kubicek is a Principal Investigator and Head of the Molecular Discovery Platform at CeMM (Center for Molecular Medicine of the Austrian Academy of Sciences). His research bridges Chemical Biology and Epigenetics , focusing on small molecules that alter cellular identity through chromatin pathways and nuclear metabolism. Previously, he led the Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, a public-private partnership with Boehringer Ingelheim and Haplogen. MSc in Synthetic Organic Chemistry (Vienna University of Technology) PhD in Molecular Biology (Thomas Jenuwein Lab, IMP Vienna) Postdoc in Chemical Biology (Stuart Schreiber, Broad Institute) His work explores ATP-dependent chromatin remodeling in cancer and diabetes, developing chemical tools against epigenetic modifiers. Recent publications highlight nuclear metabolic targets , protein phase separation , and pancreatic cell transdifferentiation . Collaborations with pharmaceutical companies have yielded high-impact studies, including Nature Genetics (2019) on synthetic lethal cancer targets. Research Funding includes: ERC Proof of Concept Grant (ONCO-SPLICE, 2024-2026) FWF Stand-Alone Program (2024-2027) WWTF Life Sciences Grant (2022-2025) Breakthrough T1D Award (2024-2025) Lab members include Predoctoral Fellows (Sandra Goll, Andreas Reicher, Jamie Reilly, Jiri Reinis, Jonathan Shklarek), Postdoctoral Fellows (Tuan-Anh Nguyen), and technicians (Maria Ciobanu, Diana Daum). His team deploys high-throughput screening , genetic code expansion , and stochastic protein tagging to uncover nuclear metabolic-epigenetic connections.

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Christoph Bockمشاهده پروفایل

استاد

University of ViennaAustria

Christoph Bock is a Principal Investigator at CeMM Research Center for Molecular Medicine and Professor/Head of the Institute of Artificial Intelligence at Medical University of Vienna. He leads the Biomedical Sequencing Facility and contributes to the Human Cell Atlas and ELLIS initiatives. Key research areas: Single-cell biology , Epigenetics , CRISPR screening , Machine learning , Cell therapy , Multi-omics Major contributions: CellWhisperer (natural language single-cell analysis), JAK-STAT signaling in immune homeostasis, LIQUORICE for liquid biopsies, and RnBeads software Scientific Awards include: ERC Starting Grant (2016) ERC Consolidator Grant (2021) Overton Prize (2017) Erwin Schrödinger Prize (2022) Clarivate Highly Cited Researcher (2019-2024) His lab develops bioinformatics tools (e.g., RnBeads, LIQUORICE) and applies systems immunology to understand disease mechanisms. Startup leadership : Co-founder of Myllia Biotechnology. Collaborations include clinical translations and tech development with the Biomedical Sequencing Facility.

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Florian Grebienمشاهده پروفایل

استاد

University of ViennaAustria

Florian Grebien is a Professor at the Department for Biological Sciences and Pathobiology, University of Veterinary Medicine Vienna, and Principal Investigator at the St. Anna Children’s Cancer Research Institute (CCRI) and Adjunct PI at CeMM. His research focuses on molecular mechanisms of pediatric leukemia driven by oncoproteins. Research Interests: Pediatric leukemia Fusion oncoproteins Transcriptional/epigenetic networks CRISPR/Cas9 screening Targeted degradation of oncoproteins Proteomic/transcriptomic analysis Scientific Awards: ERC Starting Grant His lab combines cellular models, animal models, and primary human samples to validate molecular mechanisms, collaborating with institutions like Ludwig Boltzmann Institute and CeMM. Funding sources include the European Research Council.

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