جست‌وجوی استاد و پژوهشگر

• Molecular Biotechnology
• Cellular Senescence
• Aging and Gerontology
• +۱۰ مورد دیگر

Johannes Grillari is Associate Professor at the Institute of Molecular Biotechnology, Department of Biotechnology and Food Science, University of Natural Resources and Life Sciences, Vienna (BOKU), and Director of the Ludwig Boltzmann Institute for Traumatology in collaboration with AUVA. His research bridges molecular biotechnology, aging, and regenerative medicine, with a focus on extracellular vesicles (EVs) and microRNAs in cellular senescence and tissue regeneration. Research Interests: Molecular mechanisms of cellular and organismal aging Role of miRNAs and EVs in senescence and regeneration Targeted delivery of EVs for regenerative medicine Discovery of biomarkers for aging and age-related diseases Senolytic therapies and ribosomal heterogeneity in aging His work has pioneered the understanding that EVs from senescent cells inhibit regeneration, whereas those from mesenchymal stromal cells have therapeutic potential. He has authored over 230 SCI publications and holds 15 patents, with recent research focusing on engineered EVs, EV-based diagnostics, and senolytic drug development. Scientific Awards: Walter Doberauer Prize for Aging Research (2012) Best Presentation Award, telomerase: a crystal ball for the future? (2011) Poster Prize at ECONAG 2006 Poster Prize at EMBO/Harden Conference 2004 Advising, Grants, and Leadership: Johannes Grillari leads multiple research projects funded by the Christian Doppler Research Society and the Austrian Science Fund (FWF), including the CD Laboratory for Multimodal Analytical Imaging of Skin Aging and Senescence. He is a co-founder of biotech companies in the field of senescence and EVs, and actively mentors students and early-career researchers. Labs and Research Teams: His research is conducted at the Institute of Molecular Biotechnology at BOKU and the Ludwig Boltzmann Institute for Traumatology. His team focuses on EV biology, miRNA signaling, skin and bone aging, and the development of novel therapeutic and diagnostic tools.

• Genodermatoses
• Epidermolysis Bullosa
• Gene Editing
• +۵ مورد دیگر

Dr. Josefina Pinon Hofbauer is a dedicated researcher and group leader at the Research Program for Molecular Therapy in Genodermatoses within the University Clinic for Dermatology and Allergology at Medical University of Vienna. With over two decades of research activity, she focuses on genodermatoses , particularly epidermolysis bullosa , integrating gene editing , antisense oligonucleotides , and drug repositioning to develop innovative therapies. Research Themes : Her work bridges molecular therapy , scar formation , and collagen type VII biology, addressing critical challenges in rare skin disease clinical trials. Scientific Awards : Notable recognitions include the PMU Wissenschaftspreis Gold (2011) PMU Wissenschaftspreis Silver (2012) Sanofi Award (2011) Wilhelm Türk Preis (2010) Advising : She supervised Marie-Katharina Pichler's master's thesis on hyaluronic acid effects in epidermolysis bullosa keratinocytes. Leadership in Conferences : Actively organizing events like the ÖGDV Science Days (2023-2025) and participating in the EADV Congress 2024 as a guest speaker.

• Caenorhabditis elegans
• Meiosis
• Synapsis
• +۵ مورد دیگر

Verena Jantsch is a Professor in the Department of Chromosome Biology at Max Perutz Labs, University of Vienna. With a research career spanning over three decades from 1993 to present, she has established herself as a leading expert in chromosome dynamics during meiosis using Caenorhabditis elegans as a model organism. Her research focuses on several interconnected areas of chromosome biology: Meiosis and chromosome segregation mechanisms Nuclear pore and nuclear membrane functions in chromosome organization Synapsis and homologous recombination during meiotic prophase Chromosome movement and dynamics Homologous chromosome interactions and pairing Dr. Jantsch's recent publications reveal a continued emphasis on the molecular mechanisms governing meiotic chromosome behavior, particularly examining DNA repair pathways, telomere biology, and the regulation of meiotic entry. Her work elegantly bridges molecular genetics with cell biology to understand fundamental processes of chromosome maintenance and transmission. She is currently leading multiple significant research projects including "Genome Instability" (2024-2028), "The role of DNA damage kinase DDK in meiotic recombination" (2024-2027), and mentoring postdoctoral fellow Cristina QUESADA CANDELA through the Vienna International PostDoc Program (2023-2025). As an active member of the scientific community, Dr. Jantsch regularly presents her research findings at international conferences, with upcoming presentations scheduled through 2025 on cutting-edge topics in meiotic chromosome dynamics and movement.

Joao Matosمشاهده پروفایل

استاد

• Meiosis
• Homologous Recombination
• DNA Repair
• +۵ مورد دیگر

Joao Matos is a University Professor at the Department of Chromosome Biology, Max Perutz Labs, University of Vienna, specializing in molecular mechanisms of meiosis, homologous recombination, and genome instability. His research employs genetic, biochemical, and proteomic approaches in model organisms including budding yeast and C. elegans to elucidate DNA repair pathways critical for chromosome segregation. His primary research areas encompass Meiosis , Homologous Recombination , DNA Repair , and Genome Instability , with specific focus on crossover formation, regulation of helicases (Mer3/HFM1, BLM), resolvases (Yen1/GEN1), and phosphorylation-dependent control of DNA repair enzymes. Recent work explores proteome rewiring during gametogenesis and metabolic enzyme polymers. Analysis of his 2020-2025 publications reveals consistent emphasis on meiotic recombination mechanisms, particularly helicase/resolvase regulation, D-loop dynamics, and crossover control, alongside methodological innovations in cryo-ET and proteomics. Key trends include cell cycle kinase coordination of DNA repair and stress-induced proteome remodeling. Dr. Matos has received prestigious recognition including: EMBO Long-term Fellowship (2010) EMBO Young Investigator Award (2018) ERC Consolidator Grant (2020) He currently leads three major projects: Genome Instability (2024-2028, collaborative study of DNA repair mechanisms), Vienna International PostDoc Program VIP2 (2023-2025, postdoctoral support), and Meiosis (2022-2026, molecular basis of recombination). His group mentors PhD students and postdocs while collaborating internationally on genome stability research. Based at the Max Perutz Labs (joint venture of University of Vienna and Medical University of Vienna), his team utilizes advanced cryo-electron tomography, proteomics, and genetic screening, with upcoming leadership in the 2025 EMBO Workshop on Meiosis and active participation in grant panels.

Theres Friesacherمشاهده پروفایل

پژوهشگر

• Pharmacology
• Neuroscience
• Molecular Biology
• +۳ مورد دیگر

Theres Friesacher is a Researcher at the University of Vienna's Faculty of Life Sciences, affiliated with the Department of Pharmaceutical Sciences and the Division of Pharmacology and Toxicology. She holds a BSc and MSc in relevant fields. Her research focuses on pharmacology, neuroscience, and molecular mechanisms of ion channels and cellular processes. She is reachable at theres.friesacher@univie.ac.at. Her work bridges pharmacology and molecular biology, investigating ion channel regulation (e.g., GIRK channels, GABA_A receptors) and transcriptional mechanisms. Recent studies include allosteric modulation in neuropharmacology and structural insights into potassium channels. No scientific awards are noted. She has not listed formal advisees, and her contributions are centered on collaborative lab-based research within the Division's facilities at UZA II, Vienna.

• Structural Biology
• Computational Biology
• Molecular Biology
• +۳ مورد دیگر

Anton Polyansky is a researcher affiliated with the Dr. Max Perutz Labs , part of the University of Vienna , within the Department of Structural and Computational Biology . His research focuses on structural biology, computational modeling of biomolecules, and membrane interactions. Key areas include RNA-protein interactions, transmembrane signaling, and the mechanisms behind biomolecular condensates and phase separation. He contributed to the 2' vs. 3' Aminoacylation in Biological Translation project (2017–2021), funded by research grants. His work addresses UN Sustainable Development Goals related to health and innovation, particularly in understanding cellular processes and disease mechanisms. Recent studies include atomistic analyses of diatom-guided silica formation and driving forces behind RNA polymerase condensates. Collaborations span international institutions, emphasizing computational and experimental synergies. No scientific awards are listed, but his extensive publication record (28+ papers) highlights contributions to structural biology and membrane protein dynamics. Advising and grants involve participation in funded projects, though formal student advisement details are not provided. Labs and teams include the Max Perutz Labs, collaborating with groups in computational biology and virology.

• Developmental biology
• Regenerative medicine
• Transcription
• +۳ مورد دیگر

Thomas Perlmann is a Professor of Molecular Developmental Biology at Karolinska Institutet since 2001. He serves as Secretary-General of the Nobel Assembly and Nobel Committee (2016–present) and has held leadership roles, including Director of the Ludwig Institute for Cancer Research (2007–2017) and Chairman of the Department of Cell and Molecular Biology (2003–2006). Education : PhD in Medical Science (Dr. Med. Sci.), Karolinska Institutet (1986–1991). Research Interests : The lab investigates how dopamine neurons are generated and maintained in the central nervous system, focusing on transcriptional regulation and signaling pathways. They explore early neurogenesis, adult neuronal maintenance, and regenerative medicine applications for Parkinson’s disease and related disorders. Publications : Recent work includes transcriptomic atlases of dopamine neurons, studies on Sox and Otx transcription factors, and insights into Parkinsonism pathology. Their research spans developmental neuroscience, gene regulation, and neurodegenerative disease modeling. Scientific Awards : Torsten Söderberg Academy Professor in Medicine (2017), Hilda and Alfred Eriksson’s prize (2016), Rockefeller Nicholson Award (2011), and others. Advisory Roles : Thomas serves on the board of the Nobel Foundation (2016–present) and has participated in review panels for the European Research Council and German Cancer Research Center.

Giancarlo Ruoccoمشاهده پروفایل

استاد

• Condensed Matter Physics
• Disordered Systems
• Spectroscopy
• +۷ مورد دیگر

Giancarlo Ruocco is a Full Professor of Condensed Matter Physics at Sapienza University of Rome since 2000, concurrently serving as Director of the Center for Life NanoScience (CLNS) at the Italian Institute of Technology (IIT) since 2011. He previously held leadership roles as Director of Sapienza's Physics Department (2007-2013) and Vice Rector for Research Policy (2010-2014), demonstrating sustained academic leadership across four decades. He earned his Laurea in Physics, summa cum laude, from Sapienza University of Rome in 1981, progressing through academic ranks at L'Aquila University (Assistant Professor 1984-1992, Associate Professor 1992-2000) before his appointment at Sapienza. His career reflects deep institutional commitment with progressive responsibilities. Ruocco's research centers on disordered systems (glasses/liquids) using advanced spectroscopic techniques like Brillouin scattering and inelastic X-ray scattering. He pioneered novel microscopy methods for mechanical property analysis, recently expanding into biosystems with focus on protein aggregation in neurodegenerative diseases. His interdisciplinary work bridges condensed matter physics, biophysics, and computational biology, increasingly integrating physics with biomedical applications through nanotechnology. Recent publications (2017-2021) reveal strong interdisciplinary convergence, with key themes including Brillouin microscopy for cellular mechanobiology, spin glass dynamics modeling, protein aggregation mechanisms, and confined liquid physics. His work demonstrates growing integration of experimental physics with cancer biology (organelle partitioning) and virology (SARS-CoV-2 spike protein dynamics), highlighting leadership in translating physical techniques to biomedical challenges. Major recognitions include: Membership in the Ukraine National Academy of Sciences (2021) ERC Synergy Grant ASTRA (2019) for protein aggregation research in neurodegenerative diseases He mentors a large multidisciplinary team of approximately 30 postdoctoral researchers and 20 PhD students (biologists, chemists, engineers, physicians, physicists) at CLNS/IIT. His research is funded by competitive grants including the ERC Synergy Grant, and he founded the "SOFT" Research Center at INFM (2004-2008). His leadership spans national and international collaborative projects in nanotechnology and life sciences. As Director of CLNS at IIT, Ruocco oversees a state-of-the-art facility dedicated to nanotechnology applications in biomedicine. The center hosts his "Nanotechnology for Neuroscience" research line, integrating physics, biology, and engineering expertise to develop innovative tools for neuroscience research and therapeutic development, particularly in neurodegenerative disease mechanisms.

Mart Saarmaمشاهده پروفایل

استاد

• Molecular Neurobiology
• Neurotrophic Factors
• Neurotrophic Factor Receptors
• +۷ مورد دیگر

Mart Saarma is a Professor of Biotechnology and Director of the Laboratory of Molecular Neuroscience at the University of Helsinki, Finland. With a career spanning over four decades, he has held leadership roles including Director of Biocenter Finland and Chairmanship of the Finland Centre of Excellence in Molecular Neurobiology. His academic journey includes positions at Tartu University, Estonian Academy of Sciences, and part-time affiliation with Tallinn Technical University. Education: MSc in Molecular Biology, Tartu University (1972) PhD in Ribosomal RNA-Protein Interaction, Tartu University (1975) Mart Saarma's research focuses on neurotrophic factors and their receptors, particularly GDNF family proteins. His team discovered CDNF, which shows neurorestorative potential in Parkinson's disease models, and MANF, which protects pancreatic β-cells in diabetes research. His work spans molecular neuroscience, neuronal death mechanisms, and translational applications of neurotrophic factors. Recent publications highlight his contributions to understanding GDNF signaling pathways, neuroprotective mechanisms in degenerative diseases, and novel receptor interactions. These works appear in high-impact journals like Nature and Journal of Neuroscience , reflecting his significant influence in molecular neuroscience and neurodegenerative disease research. Scientific Honors: Nordic Science Prize (2009) EMBO Member (2005) Foreign Member, Finnish Academy of Science (2000) Helsinki Gold Medal (2002) European Research Council Vice President Dr. Saarma has founded two biotech companies and holds ~20 patent families. He serves on scientific advisory boards of research institutes and currently sits on the EMBO Council. His discoveries of CDNF and MANF proteins have entered clinical trials in neurology and diabetes research.

Shaw Christopher Edward Dennistounمشاهده پروفایل

استاد

• Amyotrophic lateral sclerosis
• Frontotemporal dementia
• Neurodegeneration
• +۴ مورد دیگر

Christopher Shaw is a Professor at the Institute of Psychiatry, Psychology and Neuroscience, King's College London, and Director of the Maurice Wohl Clinical Neuroscience Institute. He is also an Honorary Consultant Neurologist at King’s College Hospital. World-leading researcher in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) Pioneer in discovering ALS genetic etiology and developing gene therapies Founder of Aviadobio, a gene therapy company targeting FTD and ALS His research focuses on molecular neurobiology, neurogenetics, and RNA processing mechanisms in neurodegenerative diseases, with a strong emphasis on translational applications like AAV-based gene therapy. Scientific Awards: Kea World Class New Zealander Award (2019) Sheila Essey Prize for ALS Research (2012) Fellow of the Academy of Medical Sciences (2010) Forbes Norris Award (2009) King’s College London Best Research Project Prize (2009) Leadership & Grants: Spearheaded £50m funding for the Maurice Wohl Clinical Neuroscience Institute and secured an additional £20m for equipment and the UK Dementia Research Institute Centre at King’s. His lab provides open-access resources including >50 familial ALS iPSC lines and transgenic mouse models for TARDBP, FUS, C9orf72, and ANXA11.

Edith Heardمشاهده پروفایل

استاد

• Epigenetics
• Genetics
• Developmental Biology
• +۳ مورد دیگر

Edith Heard is a leading academic in epigenetics and developmental biology, currently serving as Director General of the European Molecular Biology Laboratory (EMBL) since January 2019. She holds the Chair of Epigenetics and Cellular Memory at the Collège de France (since April 2012) and previously directed the Genetics and Developmental Biology department at the Curie Institute (2010-2018). Her research focuses on mechanisms of epigenetic regulation, particularly X-chromosome inactivation, chromatin dynamics, and nuclear organization. BA Cantab in Natural Sciences (Genetics), Cambridge University (1986) PhD in Biochemistry, London University (1990) Her work bridges fundamental genetic processes with broader implications in cancer and disease. She has coordinated major EU research networks like EpiGeneSys and Epigenome, and her expertise spans non-coding RNA, chromatin structure, and developmental epigenetics. She has received numerous accolades including the 2024 Croonian Medal from the Royal Society, CNRS Silver Medal (2008), and ERC Advanced Investigator Award (2010). Her leadership roles include membership in the French Academy of Sciences (2022), Royal Society, and EMBO. Principal Investigator, Mammalian Developmental Epigenetics team, Curie Institute (2001-2008) Co-Director, Genetics and Developmental Biology Unit, Curie Institute (2008-2010) Director, Genetics and Developmental Biology department, Curie Institute (2010-2018) Heard actively participates in public science outreach, teaching, and editorial activities, including co-organizing international conferences and serving on scientific advisory boards for institutions like the Institut de Génétique Humaine and the French National Research Agency (ANR).

Wilhelm T. S. Huckمشاهده پروفایل

استاد

• Physical organic chemistry
• Out-of-equilibrium complex systems
• Physical biology of the cell
• +۱ مورد دیگر

Wilhelm T. S. Huck is Professor of Physical Organic Chemistry at Radboud University in Nijmegen, The Netherlands. He leads research at the Institute for Molecules and Materials, focusing on fundamental questions about life's chemical origins and cellular processes. Previously, he held professorships at the University of Cambridge (2007-2012) and directed the Melville Laboratory for Polymer Synthesis (2004-2010). Education includes a PhD from the University of Twente (1997, supervised by Prof. David Reinhoudt) and postdoctoral research with Prof. George Whitesides at Harvard University. His research explores out-of-equilibrium reaction networks in cellular environments, physical organic chemistry of living systems, and bottom-up construction of synthetic cells. The work integrates chemical biology, biophysics, and materials science to understand how molecular interactions create life-like behaviors in complex systems. Publications demonstrate consistent focus on interdisciplinary topics: 33% concern cellular mimicry and synthetic biology, 25% examine stem cell mechanobiology, 20% develop analytical methods for biological systems, 15% advance polymer nanotechnology, and 7% explore prebiotic chemistry. Recent work emphasizes quantitative approaches to protocell development and reaction dynamics. Major scientific awards include: Spinoza Prize (NWO, 2016) Royal Netherlands Academy of Arts and Sciences membership (2012) NWO-Vici award (2011) ERC Advanced Grant (2010) Friedrich Wilhelm Bessel Research Award (2009) DuPont Young Professor Award (2004) He leads a research group supported by multiple prestigious grants including ERC Advanced and NWO-Vici funding. As co-founder of Sphere Fluidics and Cytofind Diagnostics, he bridges academic research with biotechnology applications. His laboratory develops experimental platforms for studying complex biochemical networks and synthetic cell construction.

Balasubramanian Shankarمشاهده پروفایل

استاد

• Molecular Biophysics
• Chemical Biology of Nucleic Acids
• Alternative DNA/RNA Structures
• +۳ مورد دیگر

Shankar Balasubramanian is a Professor at the University of Cambridge, holding a joint faculty appointment in the Department of Chemistry and the School of Clinical Medicine. He is renowned for pioneering advancements in nucleic acid research, particularly in DNA sequencing technologies and the study of alternative DNA/RNA structures. His work bridges molecular biophysics and chemical biology, focusing on understanding how DNA structure and modifications influence gene regulation and cellular processes, with implications for cancer and degenerative diseases. His research employs interdisciplinary approaches, from biophysical methods to genomic techniques, targeting G-quadruplex structures and epigenetic modifications. He leads the Balasubramanian Lab at the Cancer Research UK Cambridge Institute, developing tools like next-generation sequencing and methods to analyze DNA modifications. Key contributions include the reversible terminator sequencing chemistry, foundational for modern genomic studies. Awards: Breakthrough Prize in Life Sciences, Royal Medal, Millennium Technology Prize, and knighthood for contributions to sequencing. Lab Focus: G-quadruplex dynamics, epigenetic regulation, and applications to oncology. Collaborations: Joint appointments and cross-disciplinary projects spanning chemistry, medicine, and biotechnology. His research has driven technological innovations, including DNA sequencing methodologies and tools for studying secondary structures, profoundly impacting biomedical research and clinical applications.

Wendy Bickmoreمشاهده پروفایل

استاد

• Genome organisation and function
• Chromatin dynamics
• Nuclear periphery and gene regulation
• +۳ مورد دیگر

Wendy Bickmore is a Professor and Head of the Chromosomes and Gene Expression Section at the MRC Human Genetics Unit, University of Edinburgh. She specializes in genome organization, chromatin dynamics, and nuclear structure's impact on gene regulation. Her roles include leadership in the IGMM and significant editorial roles at journals like Cell and PLoS Genetics. Bickmore holds major awards including the ERC Advanced Grant (2010) and Fellowship in the Royal Society of Edinburgh (2005). Education: B.A. Biochemistry (Oxford, 1983), PhD in Genetics (Edinburgh, 1986). Career progression includes postdoctoral work, Lister Institute Fellowship, and senior scientist roles at MRC units. She organizes major conferences on nuclear organization and epigenetics, and serves on advisory boards for institutions like the Weatherall Institute. Research focuses on 3D genome architecture, polycomb complex functions, and chromatin's role in development. Over 100 citations highlight her work's impact, including groundbreaking studies on chromatin compaction and nuclear positioning effects on gene expression. Major Grants: ERC Advanced Grant (2010) Awards: 10+ national and international honors Leadership: Organized EMBO Nuclear Organisation conferences (2009–2013)

Elena Contiمشاهده پروفایل

استاد

• Structural Biology
• Biochemistry
• RNA Metabolism
• +۱ مورد دیگر

Elena Conti is an Honorary Professor at Ludwig Maximilians University, Munich, and Director of the Max Planck Institute of Biochemistry since 2006. Her work focuses on structural biology, RNA metabolism, and protein-RNA interactions. PhD in Protein Crystallography at Imperial College London (1996) Postdoctoral Fellowship at The Rockefeller University (1999) Her research explores the structural and biochemical mechanisms of RNA processing and its interactions with proteins, contributing to molecular biology and computational biology. Louis Jeantet Prize for Medicine (2014) Hans Krebs Medal (FEBS, 2011) Gottfried Wilhelm Leibniz Prize (2008) ELSO Early Career Award (2005)