جست‌وجوی استاد و پژوهشگر

Lu Chengمشاهده پروفایل

استاد مهمان

• Genomics
• Bioinformatics
• Microbial Genetics
• +۳ مورد دیگر

Lu Cheng is a Visiting Professor in the Department of Computer Science at the University of Helsinki, affiliated with the Vehtari Aki Professorship. He holds a Doctor of Philosophy in Natural Sciences from the University of Helsinki (2013). His research focuses on computational genomics, bioinformatics, and microbial genetics, with emphasis on DNA sequence analysis, nanopore sequencing technologies, and systems biology. He leads projects on alternative splicing in cancer and the impact of microbiota on human health. Notable contributions include the NanoBaseLib benchmark dataset and methods for RNA modification analysis. His work addresses UN Sustainable Development Goals related to good health and innovations in data science. Education: Doctor of Philosophy in Natural Sciences (2013), University of Helsinki; Doctoral degree in Natural Sciences (2013), University of Helsinki. Research Interests: Genomics, computational biology, microbial ecology, RNA sequencing technologies, and bioinformatics tool development. His projects explore bacterial population dynamics, host-pathogen interactions, and applications of machine learning in genomics. Advising: Supervises doctoral researchers including Guangzhao Cheng and Chengbo Fu. Active in grants such as the Academy of Finland Research Fellowship (2023-2025). Labs/Teams: Leads research groups focused on single-cell genomics and computational methods for biological systems.

• Epigenetic Mechanisms
• Cancer Therapy
• Cell Signaling
• +۴ مورد دیگر

Elenae Vazquez Ulloa is a Project Researcher at the Faculty of Science and Engineering, Åbo Akademi University, specializing in Biochemistry and Cell Biology within the InFLAMES Flagship initiative focused on immune system innovations. Her work centers on epigenetic mechanisms and their applications in cancer therapy. Research Interests Epigenetic drug development Notch signaling pathways Regulated intramembrane proteolysis Bidirectional signaling dynamics Cancer therapy resistance reversal Publication Trends 2023 review article on epigenetic modifications for cancer treatment 2022 critical analysis of Notch ligand signaling reversibility Collaborative work with experts in pharmacology and molecular biology

• Molecular Biology
• Virology
• Biochemistry
• +۷ مورد دیگر

Leif Peter Sarin is an Adjunct Professor and University Lecturer in Molecular Biology at the University of Helsinki , affiliated with the Faculty of Biological and Environmental Sciences and Molecular and Integrative Biosciences Research Programme . He leads the RNAcious laboratory and supervises doctoral and Master’s students. Doctor of Philosophy in Molecular Virology (University of Helsinki, 2005-2010) Master of Science in General Microbiology (University of Helsinki, 2005) Title of Docent (Adjunct Professor) in Molecular Biology (University of Helsinki, 2014) His research focuses on post-transcriptional RNA modifications , transfer RNA , translation regulation , and host-pathogen interactions , with applications in synthetic biology and industrial biotechnology . Recent publications explore RNA sequencing methods, tRNA dynamics in marine bacteria, and roles of noncoding RNA in cancer. Scientific awards include the Sigrid Jusélius Fellowship 2012-2014 . Key projects: PROMOTE (2023-) and ProteRNA (2019-2025), funded by the Academy of Finland and Research Council of Finland. He has supervised doctoral and Master’s students, including Matea Radešić and Lampi, M. , and hosted international researchers like Jocelyne DiRuggiero . His work spans virology, biochemistry, and RNA biology, with over 33 publications and 72 collaborative activities.

• Bioinformatics
• Computational Biology
• Epigenetics
• +۳ مورد دیگر

Maia Aisha Malonzo is a Researcher at the Computational Biology Research Group in the Department of Computer Science at Aalto University . She specializes in Bioinformatics and Epigenetics , with a focus on DNA methylation analysis, transcriptome profiling, and computational modeling of biological systems. Key collaborations with Harri Lähdesmäki 's research team Active in Statistical Genetics and Genomic Data Analysis Her research involves: Developing computational methods for epigenetic profiling (LuxHMM, LuxRep) Investigating DNA methylation changes in disease contexts like Alzheimer's and asthma Elucidating regulatory mechanisms in human pluripotent stem cells

• Biochemistry
• Cell and Molecular Biology
• Industrial Biotechnology
• +۴ مورد دیگر

Peter Sarin is a University Lecturer and Group Leader at the University of Helsinki's Faculty of Biological and Environmental Sciences within the Molecular and Integrative Biosciences Research Programme . His research focuses on the intersection of Biochemistry, Cell and Molecular Biology with applications in Industrial Biotechnology and Microbiology/Virology . Education: Doctor of Philosophy (Molecular Virology), Docent in Molecular Biology Peter's work explores post-transcriptional RNA modifications as critical regulators of translation and infection dynamics. His recent publications highlight innovative approaches to RNA sequencing, tRNA modification analysis, and applications in cancer biology and extremophile research. Scientific awards include the Sigrid Jusélius Fellowship (2012-2014) , supporting his groundbreaking research in RNA biology. He actively supervises doctoral and Master's students, participates in grant reviews (e.g., Research Council of Finland projects), and contributes to scientific discourse through editorial roles and conference organization.

Pavlina Gregorovaمشاهده پروفایل

پژوهشگر

• Biochemistry, cell and molecular biology
• Biomedicine
• Microbiology and virology

Pavlina Gregorova is a Doctoral Researcher at the University of Helsinki , affiliated with the Faculty of Biological and Environmental Sciences and the Molecular and Integrative Biosciences Research Programme . Her work bridges biochemistry, molecular biology, and microbiology. Biochemistry, cell and molecular biology Biomedicine Microbiology and virology Research Interests focus on post-transcriptional RNA modifications, particularly their role in translation regulation and infection dynamics. Recent studies explore tRNA cleavage in extremophiles, RNA modifications in prostate cancer, and aging-related protein structural changes. Scientific Contributions include developing novel methods for RNA virus quantification, analyzing RNA modification landscapes, and characterizing enzyme-polymerization-based longevity controls. Her work spans Microorganisms , Nucleic Acids Research , and Molecular Cell . Fulbright Finland Foundation Travel Grant for Research Collaboration (2020) She actively supervises Master's theses and participates in international collaborations, including a research visit at Johns Hopkins University . Gregorova contributes to organizations like the RNA Society and Societas biochemica, biophysica et microbiologica Fenniae .

Muhammad Qasimمشاهده پروفایل

پژوهشگر

• Biochemistry, cell and molecular biology
• Microbiology and virology

Muhammad Qasim is a Doctoral Researcher at the University of Helsinki, affiliated with the Faculty of Biological and Environmental Sciences and the Molecular and Integrative Biosciences Research Programme. His research focuses on RNA biology, microbiology, and molecular adaptations in extremophilic organisms. Research Interests: RNA sequencing in non-model organisms Dynamic tRNA modifications under stress Marine bacterial physiology Plant developmental RNA metabolism Scientific Awards: FEMS JOURNALS ORAL PRESENTATION PRIZE (2020) Project Highlights: ProteRNA (2019–2025): Enhancing heterologous protein production via RNA modification

• Proteomics
• Proteogenomics
• Cancer Research
• +۴ مورد دیگر

Janne Lehtiö is a Professor in Medical Proteomics at Karolinska Institutet's Department of Oncology-Pathology in Stockholm, Sweden. He has held continuous positions at Karolinska Institutet since 2004, progressing from Senior Scientist to Associate Professor and currently Professor. His research focuses on proteomics and proteogenomics applications in cancer research and precision medicine. Lehtiö earned his PhD in School of Biotechnology from Kungliga Tekniska Högskolan (Royal Institute of Technology) in Stockholm (1997-2001) and his Master of Science in Department of Biochemistry from Helsingin Yliopisto (University of Helsinki) in Finland (1991-1997). Prior to his academic career at Karolinska, he worked as a Field Scientist at Ciphergen Biosystems Inc. in Fremont, California (2001-2003). His research interests center on proteomics, proteogenomics, cancer biology, and precision medicine . Lehtiö's work bridges molecular biology with clinical applications, particularly in cancer diagnostics and treatment selection. His laboratory develops advanced proteomic technologies for in-depth molecular phenotyping of cancer. Analysis of his recent publications reveals a strong trend toward clinical proteogenomics with emphasis on spatial proteomics, immune-oncology, and biomarker discovery. His research increasingly integrates machine learning approaches for early cancer detection and treatment response prediction, with significant focus on lung cancer, ovarian cancer, and lymphoma. Lehtiö serves as Principal Investigator on numerous research grants and has extensive experience as a peer reviewer for high-impact journals including Nature Communications, Cell, and Nature Genetics. His research is supported by substantial grant funding from major Swedish research organizations including the Swedish Research Council (VR), Swedish Cancer Society, and VINNOVA. Current projects focus on proteogenomics for cancer immunotherapy, precision medicine infrastructure, and early lung cancer diagnosis.

• Biochemistry
• Cell and Molecular Biology
• Transcription
• +۶ مورد دیگر

Harri Mikael Itkonen is a Researcher at the Department of Biochemistry and Developmental Biology within the Faculty of Medicine at the University of Helsinki . He supervises the Doctoral Programme in Biomedicine and leads multiple research projects focused on hormone-dependent cancers, prostate cancer, and transcriptional regulation. Current Projects: Sigrid Jusélius Foundation (2025–2026), Biomedicum Helsinki Foundation (2024–2025), Cancer Foundation (2024–2025), Academy of Finland (2023–2025). Research Areas: Biochemistry, cancer biology, glycosylation, transcription, metabolism, and kinase inhibition. Recent research trends highlight his work on CDK12/SRPK1 dependencies , O-GlcNAcylation , and CDK9-mediated immune activation in prostate cancer. These studies intersect with hormone-dependent cancer mechanisms and RNA polymerase II regulation. Grants include funding from the Sigrid Jusélius Foundation , Biomedicum Helsinki Foundation , Cancer Foundation , and Academy of Finland , supporting investigations into transcriptional and metabolic regulation in cancer biology.

• Biochemistry
• Cell Biology
• Molecular Biology
• +۴ مورد دیگر

Aishwarya Sanjeev Gondane is a visiting researcher at Medicum , University of Helsinki, with research focusing on biochemical and molecular mechanisms in aggressive prostate cancer. Her email address is aishwarya.gondane@helsinki.fi . She is actively involved in the O-GlcNAc transferase-dependent regulation of RNA Polymerase II project funded by the Academy of Finland (2023–2025). Her research spans Biochemistry, Molecular Biology, and Cancer Research , with specific emphasis on O-GlcNAcylation, kinase signaling, and RNA polymerase regulation. Recent work explores how post-translational modifications affect mRNA maturation and tumor progression, as well as immune responses in genetic models. Key publications (2021–2025) analyze CDK12 and CDK9 inhibition in prostate cancer, O-GlcNAc transferase dependencies, and NHLRC2 variants affecting immunity. Collaborations include researchers like HM Itkonen, J Liang, and S Yalala. The O-GlcNAc transferase-dependent regulation of RNA Polymerase II project (Academy of Finland) involves her as a participant, aiming to uncover metabolic-epigenetic crosstalk in aggressive prostate cancer.

Jukka Westermarckمشاهده پروفایل

استاد

• Cancer Biology
• Signal Transduction
• Tumor Suppression
• +۲ مورد دیگر

Jukka Westermarck is a Professor of Cancer Biology and Research Director at the Turku Bioscience Centre, University of Turku. His career spans postdoctoral work at EMBL Heidelberg (1999-2001), leadership roles at Turku Centre for Biotechnology (2002-2006, 2009-present), a tenure as group leader at the Institute of Medical Technology (University of Tampere, 2006-2009), and a visiting professorship at Dana-Farber Cancer Institute (2012). His research centers on the role of protein phosphatase 2A (PP2A) in cancer progression. Key contributions include discovering PP2A's tumor-suppressive mechanisms, therapeutic targeting of phosphatase regulators, and demonstrating how CIP2A and IER5L influence therapy resistance in breast and prostate cancers. Recent work explores NRF2 adaptation in HER2-inhibited oesophageal adenocarcinoma and DDX4's oncogenic roles. Scientific Awards : Young researcher prize from Finnish Medical Association Duodecim (2007) Anders Jahre young investigator prize (2009) Elected member of the Finnish Academy of Science and Letters (2017) Westermarck's laboratory (Westermarck Lab) operates within the Turku Bioscience Centre, focusing on phosphatase-based cancer mechanisms and translational applications. His work has generated novel diagnostic biomarkers and therapy targets, while his 2024 commentaries in Kauppalehti and Helsingin Sanomat highlight his engagement in national science policy debates.

• Bioinformatics
• Cancer Genomics
• Molecular Biology
• +۳ مورد دیگر

Matti Nykter is a Professor of Bioinformatics at the Faculty of Medicine and Health Technology within the Department of Biomedicine at Tampere University. His research focuses on computational biology, cancer genomics, and systems medicine with an emphasis on prostate cancer, gliomas, and epigenetic mechanisms. Key areas of investigation include: Cancer evolution and therapeutic resistance using liquid biopsy approaches Integration of multi-omics data (genomics, epigenomics, transcriptomics) Bioinformatic methods for analyzing tumor heterogeneity and clonal evolution Zebrafish models for studying host-pathogen interactions His work bridges basic science and clinical applications, developing biomarkers and computational tools for precision oncology. Recent studies explore immunogenomics of cancer, single-cell profiling of tumor microenvironments, and molecular characterization of metastatic progression. Major contributions include: Epigenetic profiling of endocrine-resistant prostate cancer Genomic analysis of Lynch syndrome-associated cancers Development of UCLIB diagnostic panel for non-invasive cancer detection Identification of therapeutic targets via single-cell and spatial transcriptomics

Riikka Lundمشاهده پروفایل

استاد مدعو

• Epigenomics
• Genomics
• Transcriptomics
• +۱۰ مورد دیگر

Riikka Lund is an Adjunct Professor in Molecular Biology and a Research Director (10%) at the Turku Bioscience Centre, Institute of Biomedicine, University of Turku. She also works as a Senior Scientist in Bioinformatics at Orion. She leads the Biomedical Epigenomics research group and has held leadership roles in national research platforms. Education: M.Sc. in Genetics, Department of Biology, University of Turku (2001) Ph.D. in Molecular Immunology and Medical Genetics, Faculty of Medicine, University of Turku (2004) Postdoctoral training, Centre for Stem Cell Biology, University of Sheffield (2007–2008) Her research focuses on epigenomics and genomics, particularly using next-generation sequencing to study molecular mechanisms in development, aging, and diseases such as type 1 diabetes and cancer. She integrates bioinformatics and functional genomics to uncover disease markers and therapeutic targets. Her work emphasizes epigenetic regulation , pluripotent stem cells , and genome-wide methods . The recent publications (2020–2023) reflect a strong focus on DNA methylation dynamics in developmental and disease contexts, including maternal health, autoimmunity, and cancer. The studies employ advanced bisulfite sequencing, single-cell analysis, and computational modeling, highlighting her expertise in bioinformatics and epigenetic data analysis. Scientific Awards: Millennium Distinct Technology Award (2013) for contributions to stem cell research She has been actively involved in research leadership, including as Head of the Finnish Functional Genomics Centre (2013–2022), co-PI of the Biocenter Finland Genome-wide Methods Platform, and co-director of the CompLifeSci Research Programme. She has also served on the editorial board of Scientific Reports . Although no students are listed, she has engaged in teaching in epigenomics, genomics, and stem cell biology. Her research is supported through national and international collaborations and infrastructure platforms. She leads the Biomedical Epigenomics Group and has conducted short research visits to institutions including the Broad Institute (USA), Diagenode (Belgium), and the University of Southern Denmark, reflecting her international engagement in cutting-edge genomics technologies.

Ehsan Pashay Ahiمشاهده پروفایل

پژوهشگر

• Genetics
• Developmental biology
• Physiology
• +۹ مورد دیگر

Ehsan Pashay Ahi is a Postdoctoral Researcher at the University of Helsinki within the Faculty of Biological and Environmental Sciences and Organismal and Evolutionary Biology Research Programme . Holding a PhD in Biology from the University of Iceland, his research bridges Genetics, Developmental Biology, Physiology, Ecology, and Evolutionary Biology . PhD, Biology, University of Iceland, Reykjavik His work focuses on: Evolutionary developmental biology (Evo-Devo) Epigenetic regulation (m6A RNA modification) Gene co-expression networks in fish Hippo signaling pathway evolution Environmental adaptation mechanisms Phenotypic diversity in cichlids Recent publications (2023-2025) examine: Sex-specific maturation timing in Atlantic salmon Carotenoid-based color evolution Environmental RNA research beyond mRNA Leptin signaling in zebrafish reproduction Scientific contributions include: European Research Council (ERC) funded project (2023-2027) on life-history genes in fishes Collaborative studies with teams across Finland, Austria, and Iceland Research trends highlight cross-disciplinary integration of: Transcriptomics Epigenetics Gene regulatory networks Comparative physiology Ecological adaptation Developmental pathway evolution

Minna Poranenمشاهده پروفایل

مدرس ارشد

• Molecular Virology
• Plant Biology
• Microbiology
• +۵ مورد دیگر

Minna Poranen is a Senior University Lecturer at the University of Helsinki within the Faculty of Biological and Environmental Sciences and the Molecular and Integrative Biosciences Research Programme . She holds an adjunct professorship in Molecular Virology and serves as Group Leader of the Molecular and Translational Virology research group, while also directing the Biomolecular Complex Purification Core Facility (Biocomplex) under the Instruct-HiLIFE research infrastructure. Her research focuses on molecular virology , particularly the biology of prokaryotic dsRNA viruses , virus assembly , and RNA replication . She develops in vitro self-assembly systems and explores viral processes for synthetic biology applications , with emphasis on RNA interference and molecular evolution of nucleic acid processing enzymes across domains of life. Recent publications highlight dsRNA-based plant protection strategies , antiviral RNAi therapies , and virus taxonomy updates . Her work spans structural biology (e.g., RNA polymerase structure), innovative RNA delivery systems , and viral genome packaging mechanisms . Excellence in Master Thesis Supervision Award (2006) China Scholarship Council Supervision Recognition (2014) Viikki Biocenter Dissertation Prize (2000) Poranen supervises doctoral and Master's theses, reviews manuscripts for journals like Nature and PLoS , and participates in national/international scientific committees. She co-leads the Instruct-ERIC structural biology infrastructure and contributes to EU-funded projects such as SusCrop for sustainable agriculture.