معرفی
Janne Lehtiö is a Professor in Medical Proteomics at Karolinska Institutet's Department of Oncology-Pathology in Stockholm, Sweden. He has held continuous positions at Karolinska Institutet since 2004, progressing from Senior Scientist to Associate Professor and currently Professor. His research focuses on proteomics and proteogenomics applications in cancer research and precision medicine.
Lehtiö earned his PhD in School of Biotechnology from Kungliga Tekniska Högskolan (Royal Institute of Technology) in Stockholm (1997-2001) and his Master of Science in Department of Biochemistry from Helsingin Yliopisto (University of Helsinki) in Finland (1991-1997). Prior to his academic career at Karolinska, he worked as a Field Scientist at Ciphergen Biosystems Inc. in Fremont, California (2001-2003).
His research interests center on proteomics, proteogenomics, cancer biology, and precision medicine. Lehtiö's work bridges molecular biology with clinical applications, particularly in cancer diagnostics and treatment selection. His laboratory develops advanced proteomic technologies for in-depth molecular phenotyping of cancer.
Analysis of his recent publications reveals a strong trend toward clinical proteogenomics with emphasis on spatial proteomics, immune-oncology, and biomarker discovery. His research increasingly integrates machine learning approaches for early cancer detection and treatment response prediction, with significant focus on lung cancer, ovarian cancer, and lymphoma.
Lehtiö serves as Principal Investigator on numerous research grants and has extensive experience as a peer reviewer for high-impact journals including Nature Communications, Cell, and Nature Genetics.
His research is supported by substantial grant funding from major Swedish research organizations including the Swedish Research Council (VR), Swedish Cancer Society, and VINNOVA. Current projects focus on proteogenomics for cancer immunotherapy, precision medicine infrastructure, and early lung cancer diagnosis.
