معرفی
Rozbeh Jafari is an Associate Professor (Docent) in the Department of Oncology-Pathology at Karolinska Institutet, Sweden, and a Principal Researcher at SciLifeLab. Since 2024, he leads the Cancer Proteogenomics and Precision Medicine in Acute Lymphoblastic Leukemia (ALL) team, focusing on translating multi-omics insights into precision therapies for leukemia.
Education & Training:
- PhD in Biomedical Sciences, Department of Chemistry and Biomedical Sciences, Karlstad University (2010)
- Postdoctoral training, Department of Biochemistry and Biophysics, Karolinska Institutet
- Docent (Associate Professor), Department of Oncology-Pathology, Karolinska Institutet (2024)
Research Focus:
Dr. Jafari’s work integrates proteogenomics and thermal proteome profiling (TPP) to decode how genomic aberrations reshape the functional proteome in leukemia. His team interrogates drug-target interactions, maps therapeutic vulnerabilities, and develops predictive models for precision therapy in both pediatric and adult ALL and AML. Key methodological pillars include quantitative proteomics, chemical proteomics, and multi-omics data integration.
Scientific Recognition:
- Assistant Professor Award, Swedish Childhood Cancer Fund (2016)
- Starting Grant, Swedish Research Council (2017)
- Senior Investigator Award, Swedish Cancer Society (2024)
Research Environment:
He leads an independent team within the larger Cancer Proteogenomics – from Methods to Clinical Applications consortium headed by Professor Janne Lehtiö at SciLifeLab/Karolinska Institutet. The team actively collaborates with clinical centers to accelerate translation of proteogenomic findings into improved patient outcomes.
