جستجوی استاد راهنمای دانشگاهی

James C. Gumbartمشاهده پروفایل

استاد مدعو

• Computational Biochemistry and Biophysics
• Membrane proteins
• Free-energy calculations
• +۷ مورد دیگر

James C. Gumbart is an Adjunct Professor in the School of Physics at Georgia Institute of Technology, with additional affiliation to the School of Chemistry and the Institute for Bioengineering and Bioscience . His research leverages molecular dynamics simulations to decode the atomic-level mechanisms of bacterial proteins and cellular structures. B.S., Physics and Mathematics, Western Illinois University, 2003 Ph.D., Physics, University of Illinois at Urbana Champaign, 2009 Dr. Gumbart's work bridges computational biophysics and biochemistry to understand: Mechanisms of bacterial membrane protein insertion and nutrient import Structural dynamics of cell wall mechanics SARS-CoV-2 spike protein interactions with ACE2 Free-energy calculations for protein-ligand binding Applications of machine learning in biomolecular simulations His publications reflect trends in membrane protein biophysics , viral dynamics , and computational drug design , with a strong emphasis on interdisciplinary techniques. Awards include multiple fellowships and grants from NSF , DOE , and NIAID . He has mentored numerous PhD students, including Zijian Zhang , David Ryoo , and Andrew Pang , whose work has advanced understanding of bacterial systems and viral proteins. The Gumbart Lab integrates high-powered supercomputing and advanced software to model biomolecular processes, fostering collaborations with institutions like the National Institutes of Health and Argonne National Laboratory .

• Developmental Psychophysiology
• Temperament and Personality Development
• Neuroscience of Shyness and Social Anxiety
• +۴ مورد دیگر

Professor Louis Schmidt is a leading academic in the Department of Psychology, Neuroscience & Behaviour at McMaster University , with a research focus on developmental psychophysiology, temperament, and the long-term effects of early adversity. His work bridges neuroscience, psychology, and behavioral science, emphasizing the interplay between brain function and socio-emotional development across the lifespan. Key research themes: Shyness, social anxiety, autism spectrum disorder, schizophrenia, and outcomes of extremely low birth weight. Recognized for mentoring postdoctoral fellow Kristie Poole, who was celebrated as a role model in the Child Emotion Laboratory. Scientific Awards : Royal Society of Canada recognition for contributions to research and scholarship. Research Trends from 15 recent publications include: Neurophysiological mechanisms of shyness (EEG, ERP, RSA) Impact of antenatal corticosteroids on adult brain function Intergenerational effects of maternal mental health interventions Cross-cultural comparisons of temperamental shyness Developmental consequences of preterm birth Behavioral and neural correlates of social anxiety in diverse populations Grants & Collaborations : Led the SNACS randomized controlled trial on antenatal corticosteroids, with applications in obstetrics and developmental neuroscience. Collaborates extensively on topics like autism spectrum disorder, schizophrenia, and emotion regulation. Labs & Teams : Directs the Child Emotion Laboratory at McMaster University, fostering interdisciplinary research on developmental psychopathology and neural mechanisms of temperament.

Janusz Bujnickiمشاهده پروفایل

استاد

• Structural Biology
• Bioinformatics
• Computational Biology
• +۴ مورد دیگر

Janusz Bujnicki is a Professor and head of the Laboratory of Bioinformatics and Protein Engineering at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), Poland. He holds concurrent roles in science policy advisory bodies, including the European Commission's Group of Chief Scientific Advisors (2015-2020, then expert) and the Polish Academy of Sciences’ advisory panel (2024-). He is also a founding member of the Association of ERC Grantees (AERG) and serves on the Scientific Advisory Board of Life Science Center at Vilnius University. Academia Europaea Member (2018-) EMBO Member (2018-) Leadership Academy for Poland (2018) His research spans structural biology, RNA modification, computational biology, and molecular evolution. He has pioneered computational methods like ModeRNA, SimRNA, and ClaRNA for RNA structure prediction and analysis, and developed databases like MODOMICS for RNA modification pathways. His work has applications in understanding RNA function and drug design targeting RNA-processing enzymes. The 15 most recent publications focus on RNA structural modeling (e.g., ModeRNA, ClaRNA, SupeRNAlign), RNA-ligand interactions (LigandRNA), and RNA modification biology (MODOMICS database). These works bridge computational methods with experimental validation in RNA enzymology and structure-function relationships. Scientific Awards: ERC Starting Grant (2010), EMBO Member (2018), Crystal Brussels Sprout (2016), Prime Minister’s Award (2014), Knight’s Cross of Polonia Restituta (2014) Grants & Leadership: Founded RNA bioinformatics infrastructure at IIMCB, led EU science policy advisory groups, and organized international research competitions (RNA Puzzles)

Pengtao Xieمشاهده پروفایل

دانشیار

• Machine Learning
• Natural Language Processing
• Machine Learning for Healthcare
• +۴ مورد دیگر

Pengtao Xie is an Associate Professor (tenured) in the Department of Electrical and Computer Engineering at UC San Diego, with cross-appointments in the Division of Biomedical Informatics and affiliations across multiple schools and institutes including the Halıcıoğlu Data Science Institute, School of Biological Sciences, and Skaggs School of Pharmacy. His research bridges human-inspired machine learning and healthcare applications. Education: PhD in Machine Learning, Carnegie Mellon University (2018) MS from Tsinghua University BS from Sichuan University Research Interests: His work focuses on machine learning inspired by human learning strategies , including learning by testing, interleaving, self-explanation, and teaching. These techniques are applied to large language models , foundation models , healthcare , and biomedicine . Recent efforts emphasize generative AI for medical image segmentation and protein function prediction. Scientific Awards: NIH MIRA Award (2025) NSF Career Award (2024) Best Graduate Teacher Award, ECE UCSD (2023) ICLR Notable-Top-5% Paper (2023) Global Top-100 Chinese Young Scholars in AI (2022) Tencent Faculty Award (2021) AMIA Doctoral Dissertation Award Finalist (2020) Siebel Scholarship (2014) Teaching & Mentorship: He has developed and taught courses such as Deep Generative Models , Probabilistic Graphical Models , and Linear Algebra and Applications . He actively mentors PhD, master's, and undergraduate students, with alumni now at CMU, Stanford, Mila, and industry roles. Labs & Teams: He leads a research group within the Center for Machine-Intelligence, Computing and Security and collaborates with the Institute for Genomic Medicine and Institute of Engineering in Medicine at UC San Diego.

Arthur Leskمشاهده پروفایل

استاد

• Bioinformatics
• Genomics
• Protein Structure
• +۳ مورد دیگر

Arthur Lesk is a Professor of Biochemistry and Molecular Biology at Pennsylvania State University since 2003. Previously, he held roles including faculty member at the clinical school of the University of Cambridge (1990–2003), group leader at the European Molecular Biology Laboratory (1987–1990), and professor of chemistry at Fairleigh Dickinson University (1971–1987). He earned a B.A. from Harvard University (1961), Ph.D. from Princeton University (1966), and M.Sc. from the University of Cambridge (1999). His research focuses on bioinformatics, genomics, protein structure, and molecular biology. He has authored 189 scientific articles, 10 books, and has an h-index of 61. Notable works include Protein Science (2021) and Introduction to Bioinformatics (2019). Lesk chairs CODATA’s Biological Macromolecules Task Group and is a Fellow of the AAAS and Royal Society of Biology. He maintains active teaching and research roles, delivering lectures globally. His contributions include advancing protein structure databases and computational methods for molecular biology. Lesk is a Life Member of Clare Hall, Cambridge, and has held visiting positions at universities in New Zealand, Australia, and Europe.

Rafael Brüschweilerمشاهده پروفایل

استاد

• Biophysical Chemistry
• Analytical Chemistry
• Protein Dynamics
• +۳ مورد دیگر

Rafael Brüschweiler is a Professor and Ohio Research Scholar at The Ohio State University, holding joint appointments in the Department of Chemistry and Biochemistry and the Department of Biological Chemistry and Pharmacology. He serves as the NMR Executive Director for the Ohio State Campus Chemical Instrument Center and the NSF-funded National Gateway Ultrahigh Field NMR Center. His research focuses on biophysical chemistry, analytical chemistry, and computational modeling, emphasizing protein dynamics, metabolomics, and NMR method development. He received his Ph.D. from ETH Zurich and completed a postdoc at the Scripps Research Institute. His research integrates experimental NMR, molecular dynamics simulations, and machine learning to study protein structure-function relationships, metabolic pathways, and biomolecular interactions. Key areas include the dynamics of oncogenic K-Ras, glucokinase glucose sensing, and nanoparticle-assisted NMR techniques. His work is funded by the NIH and NSF, with applications in biomedical diagnostics and drug discovery. Dr. Brüschweiler leads a multidisciplinary lab training students and postdocs in NMR spectroscopy, computational methods, and metabolomics. His lab developed tools like DEEP picker and COLMAR for automated NMR data analysis, contributing to the SECIM metabolomics center. He actively recruits students interested in protein dynamics, computational modeling, or metabolomics.

Matthew Kimberمشاهده پروفایل

استاد

• Structural Biology
• Bacterial Systems
• Biochemistry
• +۳ مورد دیگر

Dr. Matthew Kimber is a Professor in the Department of Molecular and Cellular Biology at the University of Guelph. His research focuses on structural biology of bacterial systems, particularly bacterial polysaccharides and microcompartments. He employs x-ray crystallography to study molecular architectures, with current projects exploring mechanisms of bacterial surface polysaccharide assembly and bacterial microcompartment function. Education: B.Sc. (Hons) Molecular Genetics and Molecular Cell Biology from the University of Toronto (1993), Ph.D. in Molecular and Medical Genetics from the University of Toronto (2000). Research Interests: Structural basis of polysaccharide assembly and modification, bacterial microcompartment structure-function relationships, and enzyme mechanisms. Key projects include studies on glycosyltransferases, carboxysomes, and aminoacetone degradation pathways. Lab Members: Current graduate students include Laura Seidel, Liam Noseworthy, Manitabhai Govind, and Shaoqian Zong. Former members include Patrick Ryan, Evan Mallette, and Tom Keeling. Lab Focus: Probing structural details of biological molecules to understand function, with emphasis on bacteria’s strategies for polysaccharide modification and microcompartment assembly. Recent work includes characterization of enzymes involved in O-antigen biosynthesis and microcompartment shell proteins.

Nicole C. Riddleمشاهده پروفایل

استاد

• Epigenetics
• Chromatin Structure
• Drosophila melanogaster
• +۳ مورد دیگر

Nicole C. Riddle is a Professor and Associate Chair for Research and Facilities in the Department of Biology at the University of Alabama at Birmingham (UAB). She holds a B.S. in Biology from the University of Missouri Columbia and a Ph.D. in Evolutionary and Population Biology from Washington University in St. Louis. Her research focuses on epigenetics and chromatin dynamics, particularly in the context of aging and sex differences using Drosophila melanogaster as a model system. Dr. Riddle's work explores how epigenetic mechanisms influence lifespan, genome stability, and phenotypic variation. She has pioneered the use of Drosophila to study exercise-induced physiological changes and their genetic underpinnings. Her lab investigates the roles of HP1 proteins in transcriptional regulation and chromatin organization, with recent studies emphasizing cross-species comparisons of aging mechanisms. Her research has been supported by grants including the BII: IISAGE project on sex-specific aging mechanisms. Notable contributions include developing novel tools like the Rotating Exercise Quantification System (REQS) to measure Drosophila activity levels. Dr. Riddle actively mentors students and postdoctoral researchers, inviting inquiries via riddlenc@uab.edu to join her lab.

• Membrane Biophysics
• Bioengineering
• Nanotechnology
• +۷ مورد دیگر

Henry Liang, Ph.D., is a Professor in the Department of Cell Physiology and Molecular Biophysics at Texas Tech University Health Sciences Center (TTUHSC), with adjunct appointments in Chemical Engineering and Chemistry at Texas Tech University. His lab focuses on bridging biology with synthetic systems through membrane biophysics and bioengineering. Research Interests: Dr. Liang's work spans membrane protein reconstitution, nanodisc technology, antimicrobial nanoparticles, blood-brain barrier targeting, and immunotherapy platforms. Key areas include: Design of synthetic proteomembranes for protein function studies Development of environmentally responsive nanoantibiotics Nanoparticle-based theranostic systems for cancer Light-driven energy transduction in biohybrid materials Publication Trends: His 15 most recent articles (2011-2023) demonstrate consistent focus on nanotechnology solutions for biomedical challenges, with evolving emphasis on antimicrobial nanostructures (35%), membrane protein platforms (30%), cancer nanomedicine (20%), and sustainable nanomaterials (15%). Methodological strengths include polymer synthesis, X-ray scattering, and biomimetic system design. Training: The Liang Lab actively recruits graduate students and postdoctoral researchers for projects in membrane biophysics and bioengineering. Current research infrastructure includes capabilities for synchrotron small-angle X-ray scattering, molecular dynamics simulations, and nanomaterial characterization.

Katherine J. Franzمشاهده پروفایل

استاد

• Bioinorganic Chemistry
• Metal Homeostasis
• Antimicrobial Agents
• +۴ مورد دیگر

Katherine J. Franz is a Professor of Chemistry at Duke University, affiliated with the Trinity College of Arts & Sciences and the Duke Cancer Institute. She holds a Ph.D. from MIT (2000) and a B.A. from Wellesley College (1995). Her research focuses on bioinorganic chemistry, particularly metal ion coordination in biological systems, with applications in antimicrobial therapies, cancer metallomics, and neurodegenerative diseases. Key projects include developing prochelators targeting fungal and bacterial pathogens, studying copper's role in antifungal drug efficacy, and designing light-activated metal complexes for controlled drug release. Dr. Franz has received numerous awards including the Camille Dreyfus Teacher-Scholar Award (2009), Sloan Research Fellowship (2008), and the NSF CAREER Award (2005). She leads a lab with 6 current students/mentees and has secured grants from NIH, NSF, and the US-Israel Binational Science Foundation. Her lab's work spans from fundamental metalloprotein studies to translational drug development, emphasizing interdisciplinary approaches in chemistry and biology. Education: Ph.D. in Chemistry, MIT, 2000 B.A. in Chemistry, Wellesley College, 1995 Research Interests: Metal homeostasis in pathogens, copper's role in antifungal resistance, prodrug design for targeted therapy, and mechanistic studies of metalloproteins. Grants: Tri-Institutional Molecular Mycology Training Program (NIH, 2024–2029) Duke PREP Biomedical Sciences Program (NIGMS, 2022–2027) Copper-Mucin Interaction Study (BSF, 2022–2026) Her lab's publications (n=15+ since 2020) highlight breakthroughs in prodrug selectivity, copper-induced protein toxicity, and histatin antifungal mechanisms. The Franz Lab actively collaborates with clinicians and computational scientists to advance therapeutic strategies addressing unmet medical needs in infectious diseases and cancer.

Sharon Rozovskyمشاهده پروفایل

استاد

• Oxidative Stress
• Protein Quality Control
• ERAD Pathway
• +۵ مورد دیگر

Sharon Rozovsky is a Professor in the Department of Chemistry and Biochemistry at the University of Delaware's College of Arts & Sciences, where she leads research on oxidative stress response mechanisms and protein quality control pathways. Her work bridges biochemistry, chemical biology, and structural biology with direct implications for understanding neurodegenerative diseases and viral pathogenesis. Her academic foundation includes a B.S. from Tel Aviv University (1994) and a Ph.D. from Columbia University (2000), establishing her expertise in protein dynamics and redox biochemistry. These credentials underpin her innovative approaches to studying cellular stress responses. Rozovsky's research program centers on selenoproteins—proteins containing the rare amino acid selenocysteine—and their critical roles in endoplasmic reticulum (ER) stress resolution. She investigates how membrane-bound selenoproteins like Selenoprotein S and K regulate the ER-associated degradation (ERAD) pathway, with recent work revealing their surprising autoproteolytic activity and involvement in SARS-CoV-2 replication. Her lab pioneers chemical tools including expressed protein ligation and advanced 77Se NMR spectroscopy to characterize these systems at molecular resolution. Analysis of her 2021-2025 publications shows dominant themes in selenoprotein structure-function relationships, ER stress mechanisms, and viral interactions, alongside methodological innovations in cryo-EM grid technology and NMR. This body of work demonstrates consistent focus on redox biochemistry with expanding applications in virology and structural biology. No major scientific awards or fellowships were explicitly documented in the available materials, though her research impact is evident through high-impact publications and methodological contributions. She directs the active Rozovsky Research Group, mentoring graduate students and postdoctoral researchers in biochemical and biophysical techniques. Her laboratory operations are supported by competitive funding including an NSF CAREER award (2011) focused on selenoprotein reactivity, reflecting sustained recognition of her innovative research program.

Sajid Alaviمشاهده پروفایل

استاد

• Food Engineering
• Extrusion Processing
• Pet Food and Feed Applications
• +۴ مورد دیگر

Dr. Sajid Alavi is a Professor in the Department of Grain Science and Industry at Kansas State University. He joined the faculty in 2002 after earning his Ph.D. in Food Science/Food Engineering from Cornell University (2002), M.S. in Agricultural and Biological Engineering from Penn State (1997), and B.S. in Agricultural Engineering from IIT (1995). His research focuses on extrusion processing in food, pet food, and feed applications, with expertise in rheology, food microstructure imaging, and process sustainability. He leads global projects in Africa, Brazil, India, and beyond, emphasizing sustainable food technologies and AI-driven processing innovations. Dr. Alavi is a recipient of the 2010 Young Research Scientist Award from the Cereals & Grains Association. He teaches GRSC 620 (Intro to Extrusion Processing) and GRSC 820 (Advanced Extrusion Processing), and has trained over 1,000 industry leaders through his renowned 'Extrusion Processing: Technology and Commercialization' short course. His work bridges food science and engineering, addressing challenges in plant-based meat analogs, nutrient bioavailability, and food aid product development. Key facilities associated with his work include the BIVAP Feed Quality Assurance Lab and Hal Ross Flour Mill. His research spans sensory analysis of meat alternatives, fiber utilization in pet food, and sustainability assessments of novel crops like intermediate wheatgrass. Recent studies explore insect protein in pet food, AI-driven extrusion optimization, and iron bioavailability in fortified foods. Dr. Alavi’s contributions span academic, industrial, and global food security domains, reflecting a commitment to innovative, scalable food solutions.

Colin Jacksonمشاهده پروفایل

دانشیار

• Enzyme Biochemistry
• Protein Engineering
• Directed Evolution
• +۳ مورد دیگر

Associate Professor Colin Jackson is affiliated with the Research School of Chemistry at the Australian National University College of Physical & Mathematical Sciences . His research spans enzyme engineering, synthetic biology, and protein evolution, with a focus on directed evolution approaches for biocatalysis and molecular biophysics. Former CSIRO and Weizmann Institute researcher Key projects: plastic degradation enzymes, viral protease inhibitors, noncanonical amino acid incorporation His work leverages ancestral sequence reconstruction and machine learning to explore protein sequence spaces, with notable outputs in fitness landscape analysis and biocatalytic applications . Recent publications highlight advancements in: Plastic biodegradation enzyme engineering Antiviral peptide design targeting SARS-CoV-2 Fluorinated noncanonical amino acids for protein studies Marine bacterial transport proteins Organophosphate resistance mechanisms While no formal awards are listed in this data, his research portfolio demonstrates strong industry and biomedical applications through: ANU Researcher Portal publications Collaborative projects with international institutions 50+ funded projects including gene therapy platforms and food waste solutions

• Structural Bioinformatics
• Protein Structure Prediction
• Immunoinformatics
• +۳ مورد دیگر

Professor Charlotte Deane is a leading academic in structural bioinformatics, holding the position of Professor at the University of Oxford's Department of Statistics and Executive Chair of the Engineering and Physical Sciences Research Council (EPSRC). She leads the Oxford Protein Informatics Group (OPIG), focusing on protein structure prediction, immunoinformatics, and AI-driven drug discovery. Her research integrates computational methods with biological insights, developing tools widely used in academia and industry. Prior roles include Head of the Department of Statistics, Deputy Head of the Mathematical, Physical and Life Sciences (MPLS) Division at Oxford, and Chief Scientist of Biologics AI at Exscientia. During the COVID-19 pandemic, she served on SAGE and as UKRI's COVID-19 Response Director. In 2022, she was awarded an MBE for her contributions to pandemic research. Her research group's work spans antibody design, T-cell receptor analysis, and small molecule discovery, with a focus on open-source software development. Current projects include advancing AI methods for protein structure prediction and therapeutic antibody engineering. Recent publications highlight innovations in computational drug design, antibody developability, and machine learning applications in structural biology.

Xi Chenمشاهده پروفایل

استاد

• Carbohydrate Chemistry
• Glycobiology
• Enzymology
• +۷ مورد دیگر

Dr. Xi Chen is a Professor in the Department of Chemistry at the University of California, Davis, where he has been a faculty member since 2003. His research spans carbohydrate chemistry, glycobiology, and cancer biology, with notable contributions to chemoenzymatic methods for glycoconjugate synthesis. Dr. Chen's work focuses on developing hybrid chemical-enzymatic approaches to synthesize complex carbohydrates and glycoconjugates, characterizing glycosyltransferase mechanisms, and designing enzyme mutants for improved catalysis. He also investigates carbohydrate-based diagnostics and therapeutics, particularly in cancer and inflammatory diseases. His recent publications highlight interdisciplinary studies linking carbohydrate metabolism to p53 tumor suppression pathways and RNA-binding protein regulation in cancer. Awards include AAAS Fellow (2015), ACS Isbell Award (2012), and NSF CAREER Award (2006). He earned his Ph.D. at Wayne State University (2000) and B.S. at Xiamen University (1994). Scientific Awards American Association for the Advancement of Science Fellow (2015) Dean's Team Award for Excellence (2013) Carbohydrate Research Award for Creativity (2013) ACS CARB Horace S. Isbell Award (2012)