جست‌وجوی استاد و پژوهشگر

Tillman U. Gerngrossمشاهده پروفایل

استاد

• Protein Engineering
• Glycoprotein Engineering
• Biotechnology
• +۳ مورد دیگر

Professor Tillman U. Gerngross is a faculty member at the Thayer School of Engineering at Dartmouth College, where he holds the rank of Professor of Engineering. His research focuses on protein engineering, glycoprotein engineering, and metabolic engineering, with significant contributions to yeast-based production systems for therapeutic proteins. He has pioneered technologies for humanizing glycosylation pathways in yeast, enabling the production of complex glycoproteins for biomedical applications. Education: BS/MS in Chemical Engineering (1989) and PhD in Molecular Biology (1991), both from the Technical University of Vienna, Austria. Research Interests: Professor Gerngross’s work bridges biotechnology and engineering, emphasizing scalable production methods for biologics. His lab has developed novel fermentation and protein expression systems, with applications in antibody engineering and metabolic pathway optimization. Awards: Member of the National Academy of Engineering (2017), 2013 National Academy of Inventors Fellow, and recipient of the 2020 Dartmouth Entrepreneurs Forum Technology Innovation Award. Entrepreneurial Ventures: Co-founder of multiple biotech companies, including GlycoFi (acquired by Merck for $400M), Adimab, Alector, Avitide (acquired by Repligen), and Adagio Therapeutics. These ventures focus on antibody discovery, cancer therapeutics, and pandemic response technologies. Grants & Funding: His startups have secured substantial funding through venture capital and strategic partnerships, reflecting their commercial viability and scientific impact. Notable milestones include Avitide’s $150M acquisition and Alector’s $2.2B valuation post-IPO. Labs & Teams: Leads a multidisciplinary research group at Thayer, collaborating with industry partners to translate academic discoveries into industrial applications. His companies employ advanced R&D teams to develop therapies and biomanufacturing solutions.

Eugene Feinbergمشاهده پروفایل

استاد

• Markov Decision Processes
• Stochastic Optimization
• Inventory Control
• +۳ مورد دیگر

Eugene Feinberg is a Distinguished Professor in the Department of Applied Mathematics and Statistics at Stony Brook University's College of Engineering and Applied Sciences. He is renowned for his extensive contributions to Markov Decision Processes (MDPs), stochastic optimization, and inventory control. Research Interests: His work spans theoretical and applied aspects of Markov Decision Processes , stochastic optimization , inventory control , healthcare decision-making , and machine learning . He has particularly focused on solving complex decision-making problems under uncertainty, with applications ranging from operations research to medical decision-making. Scientific Awards: He has been honored with the title of Distinguished Professor , recognizing his outstanding contributions to his field. Advising and Grants: While specific details on students and grants are not provided, his prolific publication record and faculty status suggest active involvement in advising and securing research funding. Contact and Resources: His university webpage can be accessed at http://www.ams.sunysb.edu/~feinberg/ , and his Google Scholar profile is available at https://scholar.google.com/citations?user=LLt--pgAAAAJ&hl=en .

• Homomorphic Encryption
• Big Data Analysis
• Database Systems
• +۶ مورد دیگر

Hayato Yamana serves as Professor at Waseda University's Faculty of Science and Engineering and concurrently holds the position of Vice President for IT Promotion and Chief Information Officer since October 2020. His academic journey began with a Dr. Eng. degree from Waseda University in 1993, followed by positions at the Electrotechnical Laboratory of MITI, before joining Waseda University as Associate Professor in 2000 and becoming full Professor in 2005. He has held significant leadership roles including Director of the Database Society of Japan and the Information Processing Society of Japan, as well as Vice Chair of IEICE's Information and Communication Society. Waseda University, Faculty of Science and Engineering (2005-Present) National Institute of Informatics, Visiting Professor (2005-Present) Waseda University, Vice President for IT Promotion (2020-Present) Deputy Chief Information Officer (2015-2020) His research spans homomorphic encryption, big data analysis, and computer architecture, with notable contributions in privacy-preserving computation, recommender systems, and secure data processing. His work bridges theoretical cryptography with practical applications in smart cities, healthcare, and e-commerce security. Recent publications demonstrate strong focus on accelerating homomorphic encryption operations, improving recommendation system diversity, and developing novel authentication mechanisms. Analysis of his 15 most recent publications reveals consistent emphasis on privacy-preserving technologies (particularly homomorphic encryption applications), innovative recommender system architectures, and biometric security solutions. His research group produces highly cited work at the intersection of cryptography, machine learning, and systems security, with practical implementations in real-world scenarios including smart grids, e-commerce, and healthcare. Fellow, Information Processing Society of Japan (IPSJ), 2020 Golden Core Award, IEEE Computer Society, 2018 Fellow, Institute of Electronics, Information and Communication Engineers (IEICE), 2018 IBM Faculty Award, 2009 Multiple Best Paper Awards from IEICE, IPSJ, and ITE Yamana has secured substantial research funding for projects in homomorphic encryption, smart city infrastructure, and privacy-preserving systems. His leadership extends to advising numerous doctoral students and directing major research initiatives including the Smart Systems and Services Innovative Professional Education Program. He maintains active collaborations with industry partners through projects involving secure computation and data analytics. His research group operates at the forefront of secure computing, with specialized laboratories focused on homomorphic encryption acceleration, privacy-preserving machine learning, and secure mobile authentication. The team actively develops practical implementations of cryptographic protocols for real-world applications in healthcare, finance, and smart city infrastructure, bridging theoretical cryptography with deployable security solutions.

• Data Mining
• Clustering
• Outlier Detection
• +۴ مورد دیگر

Joerg Sander is a Professor and Chair of the Department of Computing Science at the University of Alberta's Faculty of Science. His research focuses on knowledge discovery in databases, particularly density-based clustering (e.g., DBSCAN, OPTICS, HDBSCAN*) and outlier detection (e.g., LOF). He is a leading contributor to foundational algorithms in data mining, including the DBSCAN paper which received the 2014 SIGKDD Test-of-Time Award. Education: M.A., Philosophy of Science (University of Munich, 1989) Diploma in Computer Science (University of Munich, 1996) Ph.D., Computer Science (University of Munich, 1998) Research Interests: Design and theoretical analysis of clustering algorithms Outlier detection methodologies Spatial and high-dimensional data mining Algorithm scalability and visualization Key Contributions: DBSCAN (density-based spatial clustering of applications with noise) OPTICS (ordering points to identify the clustering structure) LOF (local outlier factor) Awards: SIGKDD Test-of-Time Award (2014)

Antti Posoمشاهده پروفایل

استاد

• Drug Design
• Molecular Modeling
• Anti-Cancer Drugs
• +۳ مورد دیگر

Antti Poso is a Professor of Drug Design at the University of Eastern Finland (Kuopio), affiliated with the School of Pharmacy under the Faculty of Health Sciences. His research focuses on computer-aided molecular design, particularly targeting anti-cancer drugs and anti-microbials. Key projects include the EDCMET project (2019–2024) and the GeneCellNano Flagship (2020–2028). He leads the Molecular Modeling and Drug Design Research Group, specializing in QSAR analysis, kinase inhibition profiling, and systems-level drug response modeling. Recent work includes studies on SARS-CoV-2 inhibitors, endocrine disruptors, and bacterial pathogenesis. His findings bridge chemical structure with biological outcomes, leveraging computational tools like CCA and molecular dynamics simulations. Collaborations span medicinal chemistry, pharmacology, and systems biology, contributing to both academic and applied drug discovery efforts. Education: Not explicitly stated in texts; assumed to hold advanced degrees in pharmacy or chemistry. Research Themes: Drug design, molecular modeling, QSAR, computational biology, and anti-infective agents. Key Contributions: Over 150+ publications, including influential works on chemoinformatics-driven drug response analysis and structure-based inhibitor design. Publications highlight advancements in kinase inhibitors, anti-microbial strategies, and viral hijacking mechanisms. His work emphasizes translating computational insights into therapeutic solutions for cancer, infectious diseases, and metabolic disorders.

Lan Guanمشاهده پروفایل

استاد

• Membrane transport
• Membrane proteins
• Solute transport mechanisms
• +۶ مورد دیگر

Lan Guan is a Professor at Texas Tech University Health Sciences Center in the Department of Cell Physiology and Molecular Biophysics within the School of Medicine. He also serves as Co-Director of the Center for Membrane Protein Research. His research focuses on membrane proteins, which constitute approximately 30% of all eukaryotic proteins and play crucial roles in many aspects of cell function. Dr. Guan's research seeks to understand the mechanisms of solute transport and lay the foundation for advances in disease treatment and human health. He employs an integrated approach including cryo-EM single-particle analysis, X-ray crystallography, ligand binding, molecular dynamics simulations, thermodynamics, genetic engineering, novel amphiphiles, and many other biochemical & biophysical analyses. His current research focuses on cation-coupled bacterial and human transporters. Dr. Guan is currently supported by an NIGMS MIRA R35 Award (2024). His publication record demonstrates expertise in membrane protein structure and function, particularly with melibiose transporters (MelB) and their mechanisms. His work spans structural biology, biochemistry, and biophysics, with significant contributions to understanding membrane transport mechanisms. His research has led to important insights into membrane protein structure-function relationships, particularly in sugar transporters. Dr. Guan's work has implications for understanding fundamental biological processes and potential therapeutic applications related to membrane transport. NIGMS MIRA R35 Award 2024 Dr. Guan actively collaborates with researchers across disciplines and institutions, as evidenced by his extensive publication record with numerous co-authors. His work bridges structural biology, biochemistry, and biophysics to advance our understanding of membrane protein function. He is affiliated with the Center for Membrane Protein Research, where he contributes to advancing methodologies for studying these challenging but critically important biological molecules. His work on novel amphiphiles and detergent design has helped overcome technical barriers in membrane protein research.

David Ackerleyمشاهده پروفایل

استاد

• Enzymes
• Synthetic biology
• Microbiology
• +۴ مورد دیگر

Professor David Ackerley (Victoria University of Wellington) is a leading microbiologist and enzyme engineer specializing in directed evolution of bacterial enzymes for biotechnological applications. As Biotechnology Programme Director since 2006, he lectures in foundational courses like BTEC101 and BTEC201. Academic rank: Professor of Biotechnology Institutional affiliation: Victoria University of Wellington Research focus areas: Microbial Biotechnology, Drug Discovery, Synthetic Biology His research employs Darwinian evolutionary principles to engineer enzymes with enhanced activities, particularly targeting non-ribosomal peptide synthetases and nitroreductases for antibiotic development and cancer therapy. Recent work explores metagenomic domain substitution in pyoverdine biosynthesis and Purpuramine R from marine sponges. Key publications demonstrate innovations in metagenomic library construction , CRISPR screening for regeneration genes, and structural characterization of engineered enzymes. His team has developed NTR 2.0 , a high-efficacy nitroreductase for targeted cell ablation. Current research projects include: Clean solutions from dirty genes: Plastic-degrading enzyme discovery Engineering enzymes for CAR T-cell-chemotherapy synergy Repurposing niclosamide against Gram-negative superbugs Grants from the Health Research Council of New Zealand, Royal Society of New Zealand, and Cancer Society of NZ support his work. Collaborations span biomedical research, synthetic biology, and environmental applications.

Silvia Cavagneroمشاهده پروفایل

استاد

• Protein Folding
• Biomolecular Spectroscopy
• Neurodegenerative Diseases
• +۴ مورد دیگر

Silvia Cavagnero is a Professor in the Department of Chemistry at the University of Wisconsin–Madison, with a research focus on protein folding and misfolding in cellular contexts. Her work integrates biomolecular spectroscopy, chemical biology, and computational methods to address fundamental questions in structural biology. B.S., First University of Rome ‘La Sapienza’ (1988) M.S., University of Arizona (1990) Ph.D., California Institute of Technology (1996) Her research explores the role of molecular chaperones like Hsp70 in protein biogenesis, the development of laser-driven NMR techniques for enhanced sensitivity, and the implications of protein aggregation in neurodegenerative diseases. Key projects include cotranslational folding studies at ribosomal exit tunnels and hyperpolarization methods for low-concentration NMR analysis. The 15 most recent publications highlight interdisciplinary advances in NMR spectroscopy optimization Protein folding kinetics Cryo-EM structural analysis Chaperone-client interactions Hsp70 antimicrobial design Hydration dynamics in folding Scientific contributions include A Prize for Going in Vivo (2017) Recognition for Diversity and Inclusion Efforts Students from the Cavagnero Group have pursued careers in academia, pharmaceutical industries, and national laboratories. Her lab emphasizes interdisciplinary training, blending physical chemistry, biology, and computational analysis.

Petra Schwilleمشاهده پروفایل

استاد

• Molecular Biophysics
• Cellular Biophysics
• Synthetic Biology
• +۵ مورد دیگر

Prof. Dr. Petra Schwille is a Director at the Max Planck Institute of Biochemistry and former C4 Professor of Biophysics at Dresden University of Technology . Her work spans molecular and cellular biophysics, synthetic biology, and single-molecule techniques. Academic disciplines: Natural sciences, biological sciences, physical sciences Key roles: Editorial Board member (Nature Methods, Biophysical Journal), Governing Council of Biophysical Society Research Focus includes membrane biophysics, protein interactions, and microfluidic systems. Her publications emphasize Fluorescence Correlation Spectroscopy (FCS) , receptor-ligand dynamics, and self-organization in bacterial cell division. Developed in vitro models for spatial regulation in cells Explored calmodulin availability and morphogen gradient formation Scientific Recognition includes prestigious awards like the Gottfried Wilhelm Leibniz Prize (2010) and the Biofuture grant (1998) . Max Planck Fellow (2005) Young Investigator Award (2003) Leadership & Service involves roles such as Dean of Studies for Nanobiophysics at TU Dresden and Vice Dean of the Dresden International Graduate School for Biomedicine and Bioengineering (DIGS-BB) . She also contributes to editorial and advisory boards in biophysics and science policy.

Luca Varaniمشاهده پروفایل

استاد

• Structural Biology
• Antibody Engineering
• Viral Pathogenesis
• +۴ مورد دیگر

Luca Varani is a Professor and Group Leader of the Structural Biology group at the Institute for Research in Biomedicine (IRB), affiliated with the Università della Svizzera italiana in Bellinzona, Switzerland. His research focuses on understanding the molecular mechanisms of antibody-pathogen interactions and engineering novel therapeutic antibodies. Education: Chemistry degree from University of Milan, PhD from MRC-Laboratory of Molecular Biology (University of Cambridge) Former postdoc at Stanford with EMBO fellowship Founder of CLBiotech (2022), a nanobody discovery and engineering startup Varani's research spans structural biology, immunology, and biophysics with emphasis on viral pathogenesis and antibody engineering. His work combines experimental and computational approaches to study antibody-antigen interactions, particularly against emerging pathogens like SARS-CoV-2, Zika, and Dengue viruses. His group has pioneered structure-guided antibody engineering techniques that have led to multiple high-impact publications in journals like Nature, Cell, and Science. Analysis of Varani's recent publications reveals a strong focus on SARS-CoV-2 antibody responses, with significant contributions to understanding neutralizing mechanisms, viral escape, and therapeutic antibody development. His work also extends to prion diseases, cancer immunology, and flaviviruses, demonstrating a multidisciplinary approach that bridges structural biology with translational medicine. As a reviewer for high-impact journals and international granting agencies, Varani contributes significantly to the scientific community. He also serves as an evaluator for European startup accelerator programs and consults for antibody biotechnology companies, translating academic research into practical applications. Varani leads a highly multidisciplinary research team that employs techniques ranging from NMR spectroscopy and X-ray crystallography to cellular assays and computational modeling. His laboratory has been instrumental in developing bispecific antibodies against SARS-CoV-2 and other pathogens, with several candidates advancing toward clinical trials.

Anne Berit C. Samuelsenمشاهده پروفایل

دانشیار

• Polysaccharide Chemistry
• Pharmacognosy
• Carbohydrate Polymers
• +۴ مورد دیگر

Anne Berit C. Samuelsen serves as Associate Professor at the Department of Pharmacy, University of Oslo, where she also holds the position of Head of Education. Her academic foundation includes a Cand.pharm. degree and Dr.scient. doctorate, establishing her expertise in pharmaceutical sciences. Her research centers on polysaccharides from natural sources—particularly higher plants, cereals, and fungi (Basidiomycota)—with specialized focus on β-glucans. Key interests include carbohydrate chemistry, pharmacognosy, and the development of biopolymer-based pharmaceutical applications. Her work bridges fundamental structural characterization with practical drug delivery solutions, notably through liposome coating technologies and immunomodulatory compound development. Recent publications reveal a strong trajectory in fungal polysaccharide research, particularly with Pleurotus eryngii and Albatrellus ovinus species. Her team employs advanced techniques like diffusion-ordered NMR spectroscopy to analyze polysaccharide structures while investigating biological activities related to immune receptor binding (Dectin-1, Toll-like receptors) and therapeutic applications. This work demonstrates consistent output in high-impact journals including Carbohydrate Polymers and ACS Applied Bio Materials . She actively contributes to academic instruction through courses such as FARM1150 (Pharmaceutically Oriented Biochemistry), FARM3100 (Pharmacognosy), and FARM5200 (Use of Biopolymers in Pharmaceuticals). Her leadership extends to the Bioactive Natural Substances and Health Effects (BioNatH) research group and the Glyconor Consortium, where she investigates natural product applications for health improvement.

Horst A. von Recumمشاهده پروفایل

استاد

• Drug Delivery Systems
• Biomedical Engineering
• Stem Cell Differentiation
• +۴ مورد دیگر

Horst A. von Recum, PhD, is the Executive Vice Chair of the Case School of Engineering and a Professor in the Department of Biomedical Engineering at Case Western Reserve University. He is also a member of the Cancer Imaging Program at the Case Comprehensive Cancer Center. His research focuses on developing novel platforms for molecular and cellular delivery, including affinity-based systems for controlled drug release and directed stem cell differentiation. Key applications include HIV therapies, wound healing, ocular disease treatments, and tissue engineering. His work emphasizes improving drug delivery precision through molecular interactions and enhancing stem cell viability for therapeutic use. Dr. von Recum’s research interests span drug delivery systems, biomaterials science, and regenerative medicine. His lab explores cyclodextrin polymers for sustained antibiotic release, affinity-driven drug refilling mechanisms, and engineering biocompatible materials to combat implant-related infections. Recently, his team has investigated microbiome interactions with neural implants and developed polymer-based solutions for localized chemotherapy. Notable contributions include advancements in PMMA bone cement composites for drug refillable depots, cyclodextrin hydrogels for controlled release, and affinity-based systems for anti-fibrotic treatments. His work bridges materials science with clinical applications, addressing challenges in orthopedic infections, neural interfaces, and cardiovascular regeneration. Scientific achievements include over 100 peer-reviewed publications. Research funding has supported projects on antimicrobial coatings, drug delivery mechanics, and stem cell differentiation. Dr. von Recum collaborates across disciplines to translate biomaterial innovations into clinical solutions.

Andrew Schulerمشاهده پروفایل

دانشیار

• Environmental Engineering
• Microbial Ecology
• Biological Wastewater Treatment
• +۴ مورد دیگر

Andrew J. Schuler is an Associate Professor in the Department of Civil Engineering at the University of New Mexico, where he has been since 2007. His research focuses on microbial processes in wastewater treatment and bioremediation, with particular emphasis on modeling distributed bacterial states, biofilm dynamics, and integrating molecular methods with environmental engineering. He teaches courses in water/wastewater treatment (CE 335) and biological wastewater treatment (CE 536). Ph.D., Civil and Environmental Engineering, University of California at Berkeley (1998) M.S., Civil and Environmental Engineering, UC Berkeley (1993) B.S., Civil Engineering, University of Colorado at Boulder (1987) Dr. Schuler's research addresses critical challenges in biological wastewater treatment , including: Microbial storage products and density effects on solids separation Agent-based modeling of bacterial state distributions Integrated fixed-film activated sludge (IFAS) systems Photolytic and microbial degradation of Superfund chemicals His recent publications explore biofilm surface chemistry , algae-based wastewater treatment , and computational modeling of microbial communities . Notable funded projects include NSF CAREER grants, NIEHS Superfund subprojects, and North Carolina Biotechnology Center collaborations. National Science Foundation CAREER Award (2004) Paul L. Busch Award (2008) AEESP/CH2M HILL Outstanding Doctoral Dissertation Award (1999) Japan Society for the Promotion of Science Postdoctoral Fellowship (1999) Dr. Schuler leads the Schuler Laboratory , which investigates microbial dynamics in wastewater treatment systems, develops the DisSimulator agent-based modeling tool, and provides practical solutions for activated sludge settling problems through density analysis. Current funding supports advanced research in biofilm optimization and sustainable water reuse technologies.

• Materials Science
• Condensed Matter Physics
• Nanotechnology
• +۳ مورد دیگر

Alexey Vorobiev is a Researcher at Uppsala University's Materials Physics department, focusing on neutron reflectometry and magnetic materials. His work spans thin films, superlattices, and nanoparticle interfaces. Education : Not explicitly mentioned in the text. Research Interests Vorobiev's research explores magnetic properties of materials, surface interactions, and neutron optics. Key areas include spintronics, nanoscale assembly, and thin film characterization. His work often integrates experimental methods like neutron scattering with materials engineering. Article Trends Recent publications emphasize neutron-based techniques for studying magnetic multilayers, graphene oxide behavior, and nanoparticle self-assembly, reflecting a strong focus on interfacial physics and advanced material synthesis.

Koenraad Muylaertمشاهده پروفایل

استاد

• Microalgae Ecology
• Phytoplankton Physiology
• Eutrophication
• +۷ مورد دیگر

Koenraad Muylaert is a Full Professor at the Faculty of Science, KU Leuven, and head of the Biology department at KU Leuven Kulak. His research focuses on microalgae ecology and phytoplankton physiology , with applications in eutrophication studies , wastewater treatment , and biofuel production . Based in Kortrijk, Belgium, he works with international teams in Ecuador, Qatar, and Belgium. Current projects on mountain lake eutrophication and urban aquatic systems Specializes in nano-material flocculation and omega-3 fatty acid production from microalgae Research Trends from his recent articles show emphasis on: Microalgae harvesting innovations (cellulose nanocrystals, PDMAEMA polymers) Comparative processing techniques (DAF vs sedimentation, drying methods) Biotechnological applications in flavor chemistry and microbiome interactions Laboratory operates at KU Leuven's Kortrijk campus, with strong collaborations in environmental engineering and food science . His work bridges fundamental ecological research with industrial biotechnology for sustainable solutions.