Horst A. von Recum

Horst A. von Recum, PhD, is the Executive Vice Chair of the Case School of Engineering and a Professor in the Department of Biomedical Engineering at Case Western Reserve University. He is also a member of the Cancer Imaging Program at the Case Comprehensive Cancer Center. His research focuses on developing novel platforms for molecular and cellular delivery, including affinity-based systems for controlled drug release and directed stem cell differentiation. Key applications include HIV therapies, wound healing, ocular disease treatments, and tissue engineering. His work emphasizes improving drug delivery precision through molecular interactions and enhancing stem cell viability for therapeutic use.

Dr. von Recum’s research interests span drug delivery systems, biomaterials science, and regenerative medicine. His lab explores cyclodextrin polymers for sustained antibiotic release, affinity-driven drug refilling mechanisms, and engineering biocompatible materials to combat implant-related infections. Recently, his team has investigated microbiome interactions with neural implants and developed polymer-based solutions for localized chemotherapy.

Notable contributions include advancements in PMMA bone cement composites for drug refillable depots, cyclodextrin hydrogels for controlled release, and affinity-based systems for anti-fibrotic treatments. His work bridges materials science with clinical applications, addressing challenges in orthopedic infections, neural interfaces, and cardiovascular regeneration.

Scientific achievements include over 100 peer-reviewed publications. Research funding has supported projects on antimicrobial coatings, drug delivery mechanics, and stem cell differentiation. Dr. von Recum collaborates across disciplines to translate biomaterial innovations into clinical solutions.