جست‌وجوی استاد و پژوهشگر

• Proteomics
• Metabolomics
• Plant-Microbe Interactions
• +۳ مورد دیگر

Prof. Dr. Karsten Niehaus serves as Head of the Proteome and Metabolome Research Group at the Center for Biotechnology (CeBiTec) and Faculty of Biology, University of Bielefeld. His research focuses on proteomics and metabolomics applications in plant-microbe interactions, bacterial stress responses, and disease model systems. His laboratory employs advanced mass spectrometry imaging and cell phenotyping technologies to investigate molecular responses in crops like sugar beet and grapevines under abiotic stress conditions, as well as in cancer models where differentiation therapy impacts tumor malignancy. The group also explores microbial biotechnology through Xanthomonas campestris studies on xanthan production and stress adaptation. Selected publications highlight innovations in 3D microfluidics for biomarker detection and bioinformatics platforms like MetHoS for metabolomics data analysis. His work appears in journals covering Frontiers in Plant Science , Scientific Reports , and Journal of Experimental Botany . Contact: kniehaus@cebitec.uni-bielefeld.de | Office: UHG W7-117

Patrina Paraskevopoulouمشاهده پروفایل

استاد

• Inorganic Chemistry
• Catalysis
• Nanoporous Materials
• +۳ مورد دیگر

Patrina Paraskevopoulou is a Professor of Inorganic Chemistry at the National and Kapodistrian University of Athens , where she has been affiliated since 2009. Her academic journey at the same institution includes roles as Lecturer (2009), Assistant Professor (2015), Associate Professor (2019), and Full Professor (2023). PhD in Inorganic Chemistry/Catalysis (2003, NKUA) MSc in Inorganic Chemistry/Catalysis (2000, NKUA) BSc in Chemistry (1998, NKUA) Her research spans three core areas: Synthetic Inorganic Chemistry : Transition metal clusters, redox-active ligands, and nanostructured materials Homogeneous Catalysis : Oxidation reactions, atom-transfer processes, and polymerization mechanisms Nanoporous Materials : Metal-doped aerogels for environmental, biomedical, and energy applications Recent publications highlight her work on: Alginate-based aerogels for nuclear waste removal Biopolymer aerogels for sustainable packaging Carbon aerogels for electrochemical energy storage Metathesis polymerization mechanisms Biomedical implant monitoring via ultrasound Scientific Recognition : CAS REGISTRY Innovator (2023) DAAD Research Stay Scholarship (2017-2018) Multiple Greek State Scholarships (academic excellence) She has supervised numerous PhD, MSc, and undergraduate theses while serving as Guest Editor for Polymers and Frontiers in Chemistry . Her laboratory has received funding exceeding €1,000,000 through national and European projects.

Henri Tiedgeمشاهده پروفایل

استاد

• RNA Biology
• Neurobiology
• Translational Regulation
• +۵ مورد دیگر

Henri Tiedge, PhD , is a Professor at the Department of Physiology and Pharmacology within SUNY Downstate Medical Center . His research focuses on regulatory brain cytoplasmic (BC) RNAs , particularly their role in translational control mechanisms at neuronal synapses and their implications in neurological disorders and tumor biology . Institutional Affiliation: SUNY Downstate Medical Center (College of Medicine, Physiology and Pharmacology) Academic Rank: Professor Research Domains: RNA Biology, Synaptic Plasticity, Neurodegeneration, Oncology Dr. Tiedge investigates how BC1 and BC200 RNAs regulate local protein synthesis in dendrites through interactions with eukaryotic initiation factors (eIF4A/B) . His work demonstrates that BC RNA dysregulation leads to neuronal hyperexcitability , epileptogenesis , and cognitive dysfunction , with therapeutic applications in neuropsychiatric lupus using RNA decoys. He also explores BC RNA expression in germ cells and tumors , aiming to develop diagnostic/prognostic tools for cancer. Key publications include studies on RNA transport via hnRNP A2 and Purα , autoantibody-induced RNA displacement , and cross-talk between BC RNAs and FMRP in fragile X syndrome. His work has been supported by NIH grants NS046769 and DA026110 .

• Wine Science
• Viticulture
• Food Chemistry
• +۶ مورد دیگر

Dr. Joanna Gambetta serves as a Lecturer in Food Science at the University of Newcastle , affiliated with the School of Environmental and Life Sciences . With academic qualifications from Montpellier SupAgro (MSc in Oenology and Viticulture) and the University of Adelaide (PhD in Wine Science), her research focuses on grape and wine quality assessment , biotic/abiotic stress impacts on aroma composition , and practical solutions for vineyard challenges in Australian contexts. Education : MSc in Oenology and Viticulture, Montpellier SupAgro PhD in Wine Science, University of Adelaide Research Interests span three primary domains: Antifungal microbial volatile organic compounds (VOCs) for biocontrol applications, particularly against Botrytis cinerea and Alternaria alternata through novel analytical approaches Climate change adaptation strategies in viticulture, including modeling vine phenology and mitigating sunburn damage via secondary metabolite analysis Food chemistry innovations in plant-based protein gels and dairy alternatives, integrating fermentation and enzymatic crosslinking Publication Trends reveal a multidisciplinary approach combining analytical chemistry (SPME-GC-MS, LC-MS/MS), chemometrics , and industrial collaboration . Her work bridges agricultural science with food sensory analysis , while recent studies tackle plant-based cheese development using pea protein emulsions.

Mala Radhakrishnanمشاهده پروفایل

استادیار

• Computational Biophysical Chemistry
• Drug Design
• Molecular Modeling
• +۴ مورد دیگر

Mala Radhakrishnan is an Assistant Professor in the Department of Chemistry at Wellesley College. Her work bridges computational biophysical chemistry, drug design, and interdisciplinary education, with a focus on molecular recognition and electrostatic interactions in biological systems. Harvard BA in Chemistry/Physics, MIT PhD in Physical Chemistry Collaborates with Prof. Don Elmore on antimicrobial peptides and macromolecular crowding Develops case-based molecular modeling activities for high school students Her research spans computational modeling of: Drug-target interactions in chronic myeloid leukemia Promiscuous inhibitor design to combat HIV-1 drug resistance Electrostatics in crowded cellular environments Creative pedagogical approaches combining poetry and chemistry She leads the Radhakrishnan Lab, which develops computational tools for molecular design and studies fundamental principles of biomolecular recognition. Her work has been published in Biochemistry and Molecular Biology Education and Physical Chemistry Chemical Physics , with recent projects examining: Antimicrobial peptide variants using computational methods Effects of cellular crowding on binding energetics Integration of creative writing in STEM education Radhakrishnan teaches introductory chemistry, computational chemistry, and physical chemistry courses, emphasizing numeracy and computational literacy. She authored the educational poetry collection Atomic Romances, Molecular Dances , which creatively teaches chemical concepts.

Paul Millerمشاهده پروفایل

پژوهشگر

• Molecular Pharmacology
• Structural Biology
• Neuropharmacology
• +۷ مورد دیگر

Paul Miller is a researcher in the Department of Pharmacology at the University of Cambridge, part of the School of Biological Sciences. His work focuses on the structural and molecular pharmacology of ligand-gated ion channels, particularly GABAA and glycine receptors, with a strong emphasis on allosteric modulation and receptor activation mechanisms. His research interests lie at the intersection of structural biology, neuropharmacology, and molecular biophysics. He investigates how neurosteroids, zinc, and other modulators influence receptor function, using structural and biochemical approaches to uncover mechanisms of drug action. His work contributes to understanding inhibitory neurotransmission and developing targeted CNS therapeutics. The publication record shows a consistent focus on Cys-loop receptors, especially GABA and glycine receptors, with recent work advancing structural insights into receptor activation and drug selectivity. Themes include receptor subtype specificity, allosteric modulation, metal ion effects, and high-resolution structural determination via cryo-EM and crystallography. While no formal awards are listed in the provided text, his contributions to the field are evident through high-impact publications in structural pharmacology. Paul Miller advises postgraduate researchers and contributes to the academic mission of the Department of Pharmacology. His work is supported by research grants in molecular neuroscience and structural pharmacology, though specific funding sources are not detailed. He is an active member of the department’s research and postgraduate education committees. He is involved in research groups focusing on receptor biology and the Naked Mole-Rat Initiative, contributing to innovative models in pharmacological research.

• Coordination Chemistry
• Bioinorganic Chemistry
• Inorganic Chemistry
• +۲ مورد دیگر

Sanja R. Grgurić-Šipka is a Full Professor in the Department of General and Inorganic Chemistry at the University of Belgrade's Faculty of Chemistry, where she has served since 1995. She currently heads the Department of General and Inorganic Chemistry (since October 2023) and teaches core courses including General Chemistry, Chemistry of Bioelements, and Metals and Metal Complexes in Medicine. Her educational background includes: Undergraduate studies in Chemical Sciences (1990-1994) Master's degree in Chemical Sciences (1995-1998) Doctorate in Chemical Sciences (1999-2003) All obtained at the University of Belgrade Faculty of Chemistry. Grgurić-Šipka's research focuses on coordination chemistry and bioinorganic chemistry , specifically exploring metal-based anticancer agents, particularly ruthenium and platinum complexes. Her work integrates synthetic chemistry with biological evaluation to develop novel metallodrugs targeting cancer mechanisms. She employs spectroscopic methods to study metal-biomolecule interactions and investigates structure-activity relationships to optimize therapeutic potential. Current projects emphasize sustainable innovation and 'omics' research in food and environmental contexts. Analysis of her 15 most recent publications reveals a consistent emphasis on ruthenium(II)-arene complexes for cancer therapy, with growing exploration of heterometallic systems and NSAID conjugates. Her work bridges inorganic synthesis with biological testing, demonstrating strong translational potential in medicinal chemistry. Scientific recognition includes: Lisa Meitner Fellowship from the Austrian Science Fund (2005) She actively supervises research and secures competitive funding, currently leading the Horizon 2020 project 'FoodEnTwin' (2018-2021) on 'omics' research in food and environment, and the Serbian Innovation Fund project 'Pioneering Innovation of Baby Wet Wipes' (2020-2021). Previously, she coordinated national and EU-funded projects including 'Rational Design of Biologically Active Coordination Compounds' (2011) and 'Metal Complexes Binding to Biomolecules' (2012-2016). Grgurić-Šipka contributes to the Serbian Chemical Society (member since 1994) and leads departmental innovation initiatives through the Faculty of Chemistry's Innovation Center and Center for Molecular Food Sciences.

Katja Röperمشاهده پروفایل

استاد

• Cell Biology
• Developmental Biology
• Morphogenesis
• +۵ مورد دیگر

Professor Katja Röper is an Affiliated Professor in the Department of Physiology, Development and Neuroscience at the University of Cambridge and a Principal Investigator at the MRC Laboratory of Molecular Biology. She leads an active research laboratory investigating the cellular mechanisms that determine organ shape during embryonic development. Her research focuses on: Cell biology of dynamic epithelia during organ formation Cytoskeletal mechanisms (actomyosin cortex and microtubules) in morphogenesis Tubular organ formation through epithelial sheet transformation Drosophila salivary gland development as a model system Human renal organoids for understanding nephron morphogenesis Dr. Röper's work addresses how cell shape determination and coordination between neighboring cells creates complex three-dimensional organ structures from simple epithelial sheets. Her research has significant implications for understanding diseases related to defective tube formation such as Spina Bifida and Polycystic Kidney Disease, as many critical organ systems (intestinal tract, kidney, liver, lung, vasculature) maintain epithelial tubular structures. Her recent publications demonstrate a consistent focus on cytoskeletal organization, tissue patterning, and morphogenetic mechanisms across multiple model systems. She employs both Drosophila embryogenesis and human stem cell-derived organoids to investigate fundamental questions at different biological scales. Dr. Röper maintains active collaborations and publishes in leading journals including Development, eLife, and Nature Communications, demonstrating ongoing contributions to the field of developmental and cell biology.

Kelly Nguyenمشاهده پروفایل

پژوهشگر

• Structural Biology
• Molecular Biology
• Telomere Maintenance
• +۳ مورد دیگر

Kelly Nguyen is a Researcher at the Molecular Immunity Unit of the University of Cambridge , affiliated with the MRC Laboratory of Molecular Biology (LMB). Their work focuses on elucidating the molecular architecture and regulation of telomerase, a critical enzyme for maintaining chromosome stability, and related processes in telomere biology. Research Focus: Telomere maintenance mechanisms, human telomerase holoenzyme structure, and implications for diseases like cancer and premature aging syndromes. Methodology: Integrated structural biology approaches (biochemistry, cryo-EM) combined with in vivo studies in mammalian cells. Their recent publications highlight structural insights into telomerase dimerization, recruitment, and DNA interactions, as well as spliceosomal complexes. Key trends include: Deciphering telomerase assembly and regulation via high-resolution cryo-EM. Investigating RNA-mediated processes (e.g., LINE-1 retrotransposition) and protein-DNA interactions critical for genome integrity. Group members include researchers contributing to structural studies and functional analyses of telomere biology.

• Molecular Biology
• Biochemistry
• Neurodegenerative Diseases
• +۱۰ مورد دیگر

Dr. Andrey L. Karamyshev is an Associate Professor at the School of Medicine, Texas Tech University Health Sciences Center, in the Department of Cell Biology & Biochemistry. His research focuses on molecular mechanisms of human diseases, particularly neurodegenerative disorders and cancer, through the lens of protein synthesis regulation and quality control. Academic Rank: Associate Professor Research Affiliation: Institute for One Health Innovation Research Interests include: Molecular mechanisms of translational regulation RNA and protein quality control Protein interactions in health and disease Signal Recognition Particle (SRP) dysfunction in neurodegenerative diseases Role of AGO2 in mRNA degradation Co-translational protein folding and targeting Recent Publications highlight his work on the RAPP pathway, SRP interactions in Leishmania, and protein misfolding in Parkinson’s and Alzheimer’s diseases. His studies integrate in vivo and in vitro methodologies, including photo-crosslinking and iPINCH techniques. Scientific Awards & Recognition : Featured in Trends in Biochemical Sciences (2014) Highlighted in Nature Reviews Genetics (2014) Recommended by Faculty of 1000 (F1000Prime) for multiple publications Top 5.0% viewed/downloaded article in Frontiers (2018) Dr. Karamyshev welcomes graduate students to his lab, emphasizing collaboration and innovative research in molecular biology and biomedical sciences. His lab is affiliated with the Institute for One Health Innovation, fostering interdisciplinary approaches to human disease treatment.

• Molecular Dynamics Simulation
• Biomolecular Dynamics
• Protein-Protein Interactions
• +۵ مورد دیگر

Prof. Dr. Martin Zacharias serves as Chair of Theoretical Biophysics - Molecular Dynamics at the Technical University of Munich (TUM) within the TUM School of Natural Sciences. His research group employs advanced computational methods to investigate biomolecular structure, dynamics, and interactions at atomic resolution. His research focuses on molecular dynamics simulations of biomolecules, particularly examining protein-protein and protein-DNA interactions, protein folding mechanisms, amyloid structure formation, and thermodynamics of protein-ligand binding. His work integrates computational approaches with experimental validation to understand molecular recognition processes and develop predictive models for biomolecular association. Notable scientific contributions include pioneering work on biomolecular simulation methodologies, with significant publications in Nature Methods , Science , and Journal of the American Chemical Society . His recent research emphasizes implementing FAIR principles in computational biophysics and applying artificial intelligence to complex biomolecular problems. Member of the Faculty of 1000 (2009) Affiliate Member PNNL (1999) DFG habilitation scholarship holder (1996) DFG research fellow (1992) Prof. Zacharias actively supervises graduate students and leads collaborative research projects investigating fundamental biophysical processes. His laboratory develops and applies molecular simulation techniques to address critical questions in structural biology and drug discovery, with particular emphasis on methodological advancements in computational biophysics.

• Endocrinology
• Metabolism
• Neuroscience
• +۳ مورد دیگر

Martin Myers is a Professor at the University of Michigan Medical School, holding appointments in Internal Medicine (Metabolism, Endocrinology, and Diabetes) and Molecular and Integrative Physiology. He serves as Center Director of the Caswell Diabetes Institute and as a member of the Michigan Diabetes Research Center. Undergraduate: AB in Molecular Biology, Princeton University (1988) MD and PhD in Cell Biology, Harvard Medical School (1997) His research focuses on the central nervous system's role in regulating blood glucose and body weight, particularly through leptin receptor signaling and hypothalamic circuits. His work explores neural mediators of metabolic diseases, obesity, and diabetes mechanisms. Recent publications highlight neuroscience-endocrinology intersections, including hypothalamic regulation, GLP-1/leptin dual agonism, and ERAD pathway contributions to metabolic control. Keywords span neural circuits, signal transduction, and energy homeostasis. Scientific Awards: Michigan Biomedical Sciences Scholar Award (2004) ASCI Membership (2005) Jerome Conn Award for Excellence in Research (2006) American Diabetes Association’s Outstanding Scientific Achievement Award (2010) Dr. Myers has received numerous grants from NIH, Novo Nordisk, and foundations like the Warren Alpert Foundation, focusing on neural mechanisms in diabetes and obesity. He leads the Caswell Diabetes Institute and collaborates on multidisciplinary metabolic research.

• DNA Damage and Repair
• Molecular Oncology
• Cancer Biology
• +۳ مورد دیگر

Peter McHugh is Professor of Molecular Oncology at the University of Oxford, serving as Director of Oncology Laboratories at the Weatherall Institute of Molecular Medicine (WIMM) and Head of the DNA Damage and Repair Group within the Department of Oncology. His research focuses on understanding DNA damage and repair mechanisms to elucidate cancer causes and improve treatment strategies. McHugh completed his D.Phil in Biochemistry at the University of Oxford in 1996, following a BSc (Hons) in Biochemistry from UMIST in 1991. His postdoctoral training included positions as a Post-Doctoral Fellow at University College London (1997-2001) and as a Royal Society Research Fellow at UCL (2001-2002). His research program centers on molecular mechanisms of DNA repair pathways, particularly investigating nucleases like SNM1A and repair processes for complex DNA damage including interstrand crosslinks. McHugh's work spans structural biology, biochemical characterization of repair enzymes, and translational applications for cancer therapy. His laboratory employs approaches ranging from single-molecule analysis to cellular and animal models to understand how DNA repair deficiencies contribute to cancer development and how these pathways can be targeted therapeutically. Analysis of his recent publications reveals a consistent focus on DNA-protein crosslink repair, nuclease mechanisms, and the development of targeted cancer therapies. His work demonstrates strong interdisciplinary connections between basic DNA repair mechanisms and clinical oncology applications, with particular emphasis on identifying novel therapeutic targets within DNA repair pathways. Royal Society Research Fellow (2001-2002) As Director of Oncology Laboratories at WIMM and Head of the DNA Damage and Repair Group, Professor McHugh oversees significant research infrastructure and leads a team investigating fundamental mechanisms of genome maintenance. His work has implications for understanding cancer predisposition syndromes and developing targeted therapies that exploit DNA repair deficiencies in cancer cells. His laboratory maintains active collaborations across molecular oncology, structural biology, and translational medicine disciplines. The McHugh Group at the WIMM operates state-of-the-art facilities for DNA repair research, with expertise in biochemical reconstitution of repair pathways, cellular DNA damage response analysis, and development of chemical tools to probe repair mechanisms. The group maintains strong connections with clinical oncology researchers to bridge basic science discoveries with therapeutic applications.

• Immunology
• Virology
• Molecular Biology
• +۴ مورد دیگر

Jan Rehwinkel is a Professor of Innate Immunology at the University of Oxford, where he leads an independent research group within the MRC Human Immunology Unit and the MRC Weatherall Institute of Molecular Medicine. His academic journey began with undergraduate training in biology at the University of Heidelberg, Germany, followed by doctoral studies at the European Molecular Biology Laboratory (EMBL). Rehwinkel's research focuses on the molecular mechanisms of host-pathogen interactions, particularly how cells detect virus infection through nucleic acid sensing by innate immune receptors. His work sits at the intersection of immunology, virology, and molecular biology, with specific emphasis on RNA biology in innate immunity. His laboratory investigates the roles of sensors like RIG-I and ZBP1/DAI in viral recognition, inflammatory cell death pathways, and immune responses to pathogens. Analysis of his recent publications reveals a consistent focus on nucleic acid sensing mechanisms, particularly the cGAS-STING pathway, Z-nucleic acid recognition, and viral immune evasion strategies. His work spans fundamental molecular mechanisms to translational applications in viral infections, autoinflammatory diseases, and cancer immunology. The research demonstrates strong interdisciplinary connections between innate immunity, cell death pathways, and viral pathogenesis. Rehwinkel's research program is supported by prestigious funding from the Medical Research Council (MRC), Wellcome Trust, Lister Institute, and European Union grants, reflecting the significance and impact of his work in immunology and virology. His laboratory, known as the Rehwinkel Group: Nucleic Acid Sensing, operates within the MRC Human Immunology Unit at the MRC Weatherall Institute of Molecular Medicine, contributing to Oxford's strong research environment in immunology and infectious diseases. The group employs molecular, cellular, and virological approaches to dissect the complex mechanisms of innate immune recognition.

Anmar Khadraمشاهده پروفایل

استاد

• Mathematical Biology
• Computational Biology
• Complex Systems
• +۱۲ مورد دیگر

Anmar Khadra is a Full Professor in the Department of Physiology at McGill University's Faculty of Medicine. His research integrates mathematical and computational approaches to study complex biological systems across neuroscience, immunology, and cell biology, with a strong emphasis on developing predictive models that bridge multiple scales of biological organization. Dr. Khadra's research focuses on the interface of complex systems, nonlinear and stochastic dynamics, biophysics, numerical computations, and artificial intelligence. His work employs multiscale complex systems and computational AI-based models to study cellular and network dynamics in various physiological systems. Key research areas include: Neural rhythms and ion channel regulation of neural excitability System-level neural responses during rest and upon receiving stimuli Spontaneous and evoked calcium responses in neuronal and other cellular systems T cell activation mechanisms by pMHC-coated nanoparticles Cellular migration patterns and protein network regulation His recent publications (2024-2025) demonstrate a sophisticated integration of biophysical modeling with experimental validation across multiple physiological domains. The research spans from molecular-level investigations of ion channels to system-level analyses of neural populations and immune responses. A notable trend is the development of computational tools like ElecFeX for electrophysiological data analysis, alongside theoretical frameworks for understanding complex biological phenomena such as the sensitivity-specificity trade-offs in T cell responses and neural coding mechanisms. Dr. Khadra leads the Khadra Lab, which develops computational models that closely adhere to physiological properties of biological systems. These models bridge multiscale components and predict emergent behavior, generating testable predictions that guide experimental work conducted by collaborators. His research has significant implications for understanding fundamental biological processes as well as potential applications in neurological disorders, immune-related conditions, and cellular dysfunction.