جست‌وجوی استاد و پژوهشگر

Lubo Zhangمشاهده پروفایل

استاد

• Perinatal Biology
• Hypoxia Research
• Vascular Pharmacology
• +۴ مورد دیگر

Lubo Zhang, PhD, is a Professor in the Pharmacology Division at Loma Linda University School of Medicine, serving as Director of the Center for Perinatal Biology. With over 386 publications and 13 NIH-funded projects, his work focuses on hypoxia adaptation, epigenetic programming, and maternal-fetal cardiovascular interactions. Education: PhD in Biology from Iowa State University (1990) Research Interests: Zhang's research investigates hypoxia-induced vascular dysfunction, microRNA regulatory mechanisms in pulmonary hypertension, and epigenetic modifications from prenatal exposures. His team explores calcium signaling pathways in uterine artery adaptation and mitochondrial oxidative stress in pregnancy complications. Recent Publications: 2024-2025 work highlights hypoxia's role in maternal vascular tone, microRNA-210's regulation of mtROS in pulmonary hypertension, and epigenetic consequences of maternal e-cigarette exposure. Key findings connect prenatal nicotine to adult cardiovascular vulnerability and identify TET2 as a critical mediator of hypoxia responses. Awards: Recipient of the Loma Linda University Adventist Health Sciences Center Centennial Vanguard Award (2006) Funding: Research funded by NIH (NICHD, NHLBI), National Science Foundation (MRI acquisition), and institutional grants. Projects include multi-omics approaches to fetal hypoxia adaptation and development of advanced imaging techniques for neonatal brain injury.

David Patersonمشاهده پروفایل

استاد

• Cardiorespiratory Control
• Autonomic Neuroscience
• Cardiac Neurobiology
• +۱ مورد دیگر

David Paterson is Professor of Physiology and Head of the Department of Physiology, Anatomy & Genetics at the University of Oxford, a role he has held since 2016. He is also a Fellow of Merton College, Oxford, and has served in key administrative positions including Deputy Head (Vice Dean) of the Division of Medical Sciences (2008–2016). His leadership spans strategic planning and education policy, contributing to Oxford’s global ranking in Anatomy & Physiology. Paterson’s research focuses on cardiorespiratory control , autonomic neuroscience , and cardiac neurobiology . His Cardiac Neurobiology Research Group investigates neural regulation of the heart in health and disease, with emphasis on hypertension, arrhythmias, and neurocardiac signaling. Key themes include sympathetic neurotransmission, cyclic nucleotide pathways, and bioelectronic interventions for cardiovascular disorders. His recent publications (2020–2025) emphasize translational neurocardiology, exploring molecular mechanisms of sympathetic hyperactivity, stem cell-based disease models, and bioelectronic therapies. Articles consistently address autonomic dysregulation in hypertension, arrhythmia pathophysiology, and innovative diagnostic tools, reflecting interdisciplinary collaboration across physiology, neuroscience, and engineering. Major Awards & Honors: Honorary Doctorates (Otago, UWA), Fellowships (FRSB, FAPS, FPhysiol) Presidency of The Physiological Society (2020–2022) Carl Ludwig Distinguished Award, Brookhart Award Lecture Editorships: Journal of Physiology (2011–2016), Experimental Physiology (2006–2011) Paterson has supervised 27 doctoral students and secured ~£17M in funding, including a British Heart Foundation Centre of Excellence (£8.4M co-PI) and infrastructural grants for the Burdon Sanderson Cardiac Centre. His group leverages molecular, cellular, and whole-organ approaches to advance neurocardiac therapeutics.

Edor Kabashiمشاهده پروفایل

پژوهشگر

• Neurological Disorders
• Neurodevelopmental Diseases
• Neurodegenerative Diseases
• +۵ مورد دیگر

Edor Kabashi is a leading researcher in translational neuroscience, specializing in genetic causes of neurological disorders such as Developmental and Epileptic Encephalopathy (DEE), Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD). His team at the Imagine Institute (Necker Hospital site) develops advanced cellular and zebrafish models to elucidate disease mechanisms and accelerate therapeutic validation. Key research areas include iPSC-derived neurons, drug screening platforms, and genomic sequencing analysis. Collaborations span national/international networks with institutions like ANR and pharmaceutical partners. Expertise: Genetic epilepsy, neurodegeneration, translational drug development Techniques: CRISPR gene editing, induced pluripotent stem cells, high-throughput screening Current projects focus on fast-tracking neuroprotective compounds into clinical trials, leveraging state-of-the-art platforms such as transcriptomic/proteomic analysis and advanced imaging. Actively recruiting postdocs and PhD candidates with expertise in zebrafish models, molecular genetics, and bioinformatics.

• Molecular Biology
• Biochemistry
• Neurodegenerative Diseases
• +۱۰ مورد دیگر

Dr. Andrey L. Karamyshev is an Associate Professor at the School of Medicine, Texas Tech University Health Sciences Center, in the Department of Cell Biology & Biochemistry. His research focuses on molecular mechanisms of human diseases, particularly neurodegenerative disorders and cancer, through the lens of protein synthesis regulation and quality control. Academic Rank: Associate Professor Research Affiliation: Institute for One Health Innovation Research Interests include: Molecular mechanisms of translational regulation RNA and protein quality control Protein interactions in health and disease Signal Recognition Particle (SRP) dysfunction in neurodegenerative diseases Role of AGO2 in mRNA degradation Co-translational protein folding and targeting Recent Publications highlight his work on the RAPP pathway, SRP interactions in Leishmania, and protein misfolding in Parkinson’s and Alzheimer’s diseases. His studies integrate in vivo and in vitro methodologies, including photo-crosslinking and iPINCH techniques. Scientific Awards & Recognition : Featured in Trends in Biochemical Sciences (2014) Highlighted in Nature Reviews Genetics (2014) Recommended by Faculty of 1000 (F1000Prime) for multiple publications Top 5.0% viewed/downloaded article in Frontiers (2018) Dr. Karamyshev welcomes graduate students to his lab, emphasizing collaboration and innovative research in molecular biology and biomedical sciences. His lab is affiliated with the Institute for One Health Innovation, fostering interdisciplinary approaches to human disease treatment.

Michael Laneمشاهده پروفایل

دانشیار

• Spinal Cord Injury
• Neural Plasticity
• Cell Therapy
• +۴ مورد دیگر

Michael Lane, PhD, is an Associate Professor in the Department of Neurobiology & Anatomy at Drexel University College of Medicine. He leads a research team focused on spinal cord injury (SCI), particularly cervical SCI and its impact on respiratory and motor functions. His work emphasizes neural plasticity, cell transplantation therapies, and rehabilitative strategies to enhance functional recovery. Prior to Drexel, he held positions at the University of Florida and served as a lecturer at The Ohio State University. Education: PhD in Pharmacology (University of Melbourne, 2004); BSc in Anatomy and Physiology (University of Tasmania, 1999, summa cum laude). Research Interests: Spinal cord injury recovery, neural plasticity mechanisms, cell-based therapies (e.g., neural progenitor transplants), respiratory function restoration, and activity-based rehabilitation. Key projects include NIH-funded studies on respiratory training and neural transplants. Awards: Includes the Molly and Bernard Sandberg Award (2019), Best Mentor Award (2017), and election as President of the American Society for Neural Therapy and Repair (2022). Grants: Current funding includes projects on respiratory training (Pennsylvania Department of Health, 2021-2023), neural transplants (NIH NINDS R01, 2018-2023), and stem cell-derived neural progenitors (Moseley Foundation, 2019-2022). Lane Lab: Focuses on preclinical research to bridge discovery and clinical application, emphasizing strategies like cell transplantation and activity-based therapies to improve post-SCI outcomes.

• Translational Regulation
• RNA/Protein Quality Control
• Protein Misfolding
• +۵ مورد دیگر

Dr. Andrey L. Karamyshev is an Associate Professor in the Department of Cell Biology and Biochemistry at Texas Tech University Health Sciences Center's School of Medicine. His research focuses on molecular mechanisms of translational regulation and protein quality control, with significant contributions to understanding co-translational protein folding and targeting processes. He leads an active laboratory investigating fundamental cellular pathways with direct implications for human diseases. His primary research interests center on translational regulation mechanisms , particularly the RAPP (Regulation of Aberrant Protein Production) pathway discovered by his team, which monitors nascent chain interactions during translation to prevent defective protein synthesis. His work explores protein misfolding in neurodegenerative diseases like Alzheimer's and Parkinson's, investigating how loss of co-translational interactions leads to pathological aggregation. Additional research areas include ribosome specialization, mRNA quality control, and translational adaptations in parasitic organisms like Leishmania. Analysis of his recent publications (2020-2023) reveals consistent focus on protein quality control pathways , with particular emphasis on the Signal Recognition Particle (SRP) system and its intersections with neurodegenerative disease mechanisms. His work increasingly bridges fundamental molecular biology with therapeutic applications, especially in parasitic diseases and neurodegeneration. Faculty of 1000 recommendation (2014) Faculty of 1000 recommendation (2005) Faculty of 1000 recommendation (2003) Editors' Highlights in Microbiology and Infectious Diseases (Nature Communications, 2023) Dr. Karamyshev actively recruits graduate students to his laboratory, where researchers employ advanced techniques including site-specific photo-crosslinking, iPINCH (identification of Proteins Interacting with Nascent Chains), unnatural amino acid incorporation, and ribosome profiling. His lab has secured research funding supporting investigations into translational regulation mechanisms with potential pharmaceutical applications for neurodegenerative and parasitic diseases. Current projects include elucidating the complete RAPP pathway mechanism and exploring co-translational protein interactions in neurodegenerative disease models. His laboratory maintains active collaborations across Texas Tech University and Texas Tech University Health Sciences Center, particularly with parasitology and neuroscience research groups. The team utilizes specialized methodologies for studying nascent chain interactions both in vitro and in human cell culture systems, with growing focus on translational applications for disease treatment.

Benjamin Wolozinمشاهده پروفایل

استاد

• Neurodegenerative Diseases
• Alzheimer's Disease
• Parkinson's Disease
• +۷ مورد دیگر

Benjamin Wolozin is a Professor at the Boston University Chobanian & Avedisian School of Medicine in the Department of Pharmacology , with an adjunct position in Neurology. He specializes in neurodegenerative diseases, particularly Alzheimer's , Parkinson's , and ALS . MD/PhD, Albert Einstein College of Medicine Past Associate Professor at Loyola University Medical Center (1996-2004) Current affiliations: Alzheimer's Disease Center, Boston University Graduate Program for Neuroscience His research investigates RNA binding proteins (RBPs) , stress granules , and liquid-liquid phase separation in neurodegenerative disease. Key projects include the role of TIA1 and HNRNPA2B1 in tauopathy, m6A RNA methylation in Alzheimer's pathology, and development of 3D iPS-neuron/astrocyte assembloids to model dementia. His lab has identified disease-linked circRNA changes and explores nanobodies targeting stress granule components. Recent awards include the Donald B. Lindsley Prize (Society for Neuroscience) and A. E. Bennett Award . He serves on NIH CDIN study sections and editorial boards for Journal of Biological Chemistry and Neurodegenerative Diseases . Grants include multiple NIH R01 and U01 awards for AD/tauopathy research.

Qunzhou Zhangمشاهده پروفایل

عضو هیئت علمی

• Regenerative medicine
• Mesenchymal stem cell biology
• Immunomodulation and anti-inflammation
• +۴ مورد دیگر

Dr. Qunzhou Zhang, PhD, is a Research Assistant Professor in the Department of Oral and Maxillofacial Surgery / Pharmacology at the University of Pennsylvania School of Dental Medicine , Philadelphia, USA, where he has held successive appointments since 2012. He also maintains adjunct/visiting professor affiliations with Guangdong Medical University in China (2008–2016). He earned his doctoral degree in Biochemistry & Molecular Biology from West China University of Medical Sciences (now Sichuan University) in 2000, preceded by an M.Sc. from Guangdong Medical University (1997) and a B.A. in Preventive Medical Sciences from Chongqing Medical College (1990). Dr. Zhang’s research program sits at the intersection of regenerative medicine, stem cell biology, immunomodulation, and cancer . His laboratory focuses on: Immunomodulatory and anti-inflammatory functions of gingiva-derived mesenchymal stem cells (GMSCs) in rodent models of colitis, skin/oral wounds, and allergic dermatitis. Non-genetic induction of neural crest stem-like cells (NCSC) from GMSCs for peripheral nerve regeneration, including 3D bioprinted, scaffold-free nerve grafts . Paracrine mechanisms involving extracellular vesicles (exosomes) secreted by GMSCs that modulate host tissue microenvironments and promote tongue muscle/taste-bud regeneration. Tumor microenvironment studies exploring how mesenchymal stromal cells influence the pathogenesis of ameloblastoma and head & neck squamous cell carcinoma (HNSCC) . Across 50+ peer-reviewed publications since 2004, his work demonstrates a consistent trajectory from basic mechanistic studies to translation-oriented tissue engineering , with particular emphasis on exosome-based therapies and 3D bioprinting technologies . Scientific Awards & Honors Research Support Grant (RSG) , Oral and Maxillofacial Surgery Foundation (2008, 2011, 2014, 2017) Pilot Research Grant , University of Pennsylvania Diabetes Research Center Peter Geistlich Research Award , OsteoScience Foundation (2016) Honored/Adjunct Professor , Guangdong Medical University (2008–2016) Dr. Zhang has served as ad-hoc peer reviewer for more than 25 high-impact journals, including J Invest Dermatol, Stem Cells & Development, Tissue Engineering, PLOS ONE, J Dental Res, Oncotarget and others. While the provided text does not list specific PhD or Master’s students, his role as senior investigator and lab manager implies active mentoring within the university’s research programs. His laboratory is located within the Department of Oral & Maxillofacial Surgery & Pharmacology at Penn Dental Medicine, equipped for in vivo rodent surgery, stem cell culture, 3D bioprinting, and molecular profiling . Future directions include first-in-human trials of GMSC-derived exosome therapeutics and scale-up manufacturing of 3D bioprinted nerve constructs.

Mark Albersمشاهده پروفایل

استادیار

• Alzheimer's Disease
• Amyotrophic Lateral Sclerosis (ALS)
• Olfactory Disorders
• +۹ مورد دیگر

Mark Albers is an Assistant Professor of Neurology at Harvard Medical School and a clinician-investigator at Massachusetts General Hospital (MGH), where he directs the Albers Laboratory at the MassGeneral Institute for Neurodegenerative Disease (MIND). His research bridges clinical and basic science, focusing on early detection and therapeutic development for neurodegenerative diseases like Alzheimer’s, ALS, Parkinson’s, and traumatic brain injury through olfactory system studies. Education: PhD in Organic Chemistry from Harvard Graduate School of Arts and Sciences (1995), MD from Harvard Medical School (1995). Clinical Expertise: Memory and olfactory disorders; practices in the Memory Disorders Unit at MGH. His lab investigates pathogenic mechanisms of neurodegenerative disease genes using transgenic mouse models, CRISPR screens, multiphoton imaging, and in silico drug trials. Key projects include identifying olfactory deficits as early biomarkers and repurposing FDA-approved drugs for neurodegenerative diseases via the NADALS basket trial. Publications span Alzheimer’s disease , olfactory dysfunction , neuroinflammation , systems pharmacology , and CRISPR technology . Collaborations with the Laboratory of Systems Pharmacology and Harvard Program in Therapeutic Science further his translational goals.

Lorraine Iacovittiمشاهده پروفایل

استاد

• Neurodegenerative Diseases
• Stem Cells
• Parkinson's Disease
• +۲ مورد دیگر

Lorraine Iacovitti is a Professor in the Department of Neuroscience at Thomas Jefferson University, affiliated with the Vickie and Jack Farber Institute for Neuroscience and the Jefferson Stem Cell & Regenerative Neuroscience Center. Her research focuses on developing cell-based therapies for neurodegenerative disorders through stem cell differentiation studies. Her educational background includes: Post-Doctoral, Washington University-St. Louis, Anatomy & Neurobiology (1981) PhD in Neurobiology from Cornell University Medical College (1979) BS in Biology from Monmouth College (1973) Dr. Iacovitti's laboratory investigates dopamine neuron development to create molecular blueprints for treating Parkinson's disease. Using human embryonic stem cells and precursor cells, her team employs a multidisciplinary approach combining tissue culture, molecular engineering (qPCR, microarray, transfection), anatomical analysis (immunocytochemistry, confocal microscopy), biochemical assays (HPLC), stereotaxic surgery, and behavioral testing in rodent models. Current work focuses on inducing dopaminergic traits in stem cells and optimizing transplantation protocols for Parkinson's disease models. Recent publications demonstrate consistent translational focus on stem cell applications for neurological conditions, particularly stroke recovery and Parkinson's disease. Key themes include extracellular vesicle therapeutics, molecular pathways protecting dopaminergic neurons, and motor function restoration in animal models of ischemic injury. Dr. Iacovitti leads an active research laboratory within the Vickie and Jack Farber Institute for Neuroscience, utilizing advanced techniques including PET/SPECT imaging, arterial occlusion surgery, and comprehensive behavioral assessment. Her work bridges basic developmental neuroscience with preclinical cell therapy development for neurodegenerative conditions.

• Zebrafish Biology
• Neural Regeneration
• Spinal Cord Injury
• +۶ مورد دیگر

Jan Kaslin is a researcher at Life Sciences University specializing in zebrafish models to investigate neural regeneration, spinal cord injury recovery, and related biological processes. With a publication record spanning from 2016 to 2021, Dr. Kaslin's work focuses on understanding the mechanisms of neuronal circuit regeneration and functional recovery following injury. Dr. Kaslin's research interests center around zebrafish biology as a model system for studying human neurological conditions. Key areas include neural regeneration mechanisms, inflammation responses in neural repair, precursor neuron migration, spinal cord injury recovery, and molecular pathobiology of genetic disorders like Sanfilippo syndrome. The research employs advanced molecular and cellular techniques to unravel the complex processes underlying neural circuit formation and repair. Analysis of Dr. Kaslin's publications reveals a clear research trajectory focused on leveraging zebrafish's remarkable regenerative capabilities to understand neural repair mechanisms. The work spans developmental biology, neural regeneration, and disease modeling, with particular emphasis on how inflammation triggers precursor neuron migration to facilitate circuit regeneration. This research has significant implications for developing therapeutic approaches for spinal cord injuries and neurodegenerative conditions. Dr. Kaslin actively collaborates with researchers across multiple institutions, as evidenced by the co-authorship patterns in publications. The research has garnered substantial attention in the scientific community, with multiple papers receiving significant citation counts and media coverage. Current work appears focused on translating findings from zebrafish models to potential applications in human neural repair and regeneration. Dr. Kaslin's laboratory likely focuses on zebrafish neurobiology and regeneration, utilizing this powerful model organism to investigate fundamental questions about neural circuit formation, injury response, and repair mechanisms. The research program integrates molecular biology, genetics, and behavioral analysis to provide comprehensive insights into neural regeneration processes.

Nikhil Ursمشاهده پروفایل

دانشیار

• Neuroscience
• Dopamine Neurotransmission
• Neurodegenerative Diseases
• +۳ مورد دیگر

Nikhil Urs is an Associate Professor at the University of Florida, focusing on dopamine neurotransmission and its role in neurological and psychiatric disorders. His research explores signaling pathways, neuronal circuits, and behavioral outcomes in models of Parkinson's disease, schizophrenia, and ADHD. The Urs Lab integrates molecular, cellular, and behavioral approaches to develop novel therapies targeting dopamine-related disorders. Key areas include β-arrestin signaling in dopamine receptors, gut-brain axis interactions, and drug discovery for addiction and psychostimulant effects. Urs has published extensively on topics like dopamine dynamics, metabolic regulation, and GPCR pharmacology, with notable contributions in Cell Metab , Biol Psychiatry , and PNAS . His work highlights translational research bridging basic neuroscience and clinical applications. Labs/Teams: Urs Lab at the University of Florida, collaborating on projects studying dopamine pathways and therapeutic development.

• Organic Chemistry
• Synthetic Methodology
• Green Chemistry
• +۵ مورد دیگر

James Mcnulty is a Professor in the Department of Chemistry & Chemical Biology at McMaster University, Canada. He holds a B.Sc., M.Sc., and Ph.D. from the University of Toronto, followed by postdoctoral research at the University of Geneva and the Cancer Research Institute at Arizona State University. His research focuses on synthetic organic chemistry, green chemistry, organocatalysis, and the development of methodologies for natural product synthesis, particularly anticancer and antiviral agents. Dr. Mcnulty's work emphasizes the total synthesis of complex natural products, including alkaloids, and their applications in drug discovery. His group has published over 150 peer-reviewed articles, with recent studies addressing antiviral mechanisms, cannabinoid synthesis, and plant metabolomics. He teaches courses such as Natural Products Chemistry and Organic Structure/Synthesis at both undergraduate and graduate levels. Key research areas include: (1) Design of asymmetric organocatalytic methods, (2) Green chemistry approaches to reduce environmental impact, (3) Discovery of antiviral and anticancer pharmacophores from natural products, and (4) Structural elucidation of bioactive compounds.

• Molecular Genetics
• Neurobiology
• Genomics
• +۳ مورد دیگر

Jacob Berry is an Assistant Professor in the Department of Biological Sciences at the University of Alberta. His research focuses on molecular genetics, neurobiology, and Drosophila model systems. He teaches courses such as BIOL 207 (Molecular Genetics and Heredity) and laboratory modules including GENET 375/575 (Molecular Genetics Techniques), emphasizing CRISPR/Cas9 editing, DNA sequencing, and gene expression analysis. His research interests span memory mechanisms, dopamine signaling in forgetting, and cancer biology involving COX-2 pathways. Recent work explores neuroplasticity in Drosophila, sleep-motivated forgetting, and genomic instability in breast cancer models. Berry’s studies often bridge molecular genetics with neurobehavioral outcomes, using Drosophila as a key experimental model. He is affiliated with the Genetics Wing at the University of Alberta and actively contributes to undergraduate and graduate training in molecular biology techniques. No awards or grants are explicitly listed in the provided materials, though his publications reflect sustained research activity since 2004.

Marcus Grimmمشاهده پروفایل

استاد

• Alzheimer's Disease Research
• Lipid Metabolism
• Nutritional Therapy
• +۵ مورد دیگر

Professor Marcus Grimm serves as Academic Head of Centre of Research and Funding and Professor and Programme Director for the Bachelor's Programme in Nutritional Therapy and Counselling at the Cologne Campus of SRH University of Health since October 1, 2021. With a distinguished career spanning over two decades in Alzheimer's disease research, Prof. Grimm has established himself as a leading expert in the intersection of lipid metabolism and neurodegenerative disorders. Prof. Grimm completed his biochemistry studies at the Johann Wolfgang Goethe University in Frankfurt with support from the German Academic Scholarship Foundation. He earned his PhD summa cum laude from the Center for Molecular Biology (ZMBH) at Heidelberg University, where he demonstrated the bidirectional interaction between Alzheimer's disease and lipid homeostasis, publishing findings in high-impact journals including Nature Cell Biology. During his doctoral studies, he concurrently completed an MBA through distance learning. He later habilitated at Saarland University in the field of Alzheimer's disease prevention, receiving a research prize in 2010. Prof. Grimm's research program has consistently focused on understanding the molecular mechanisms linking lipid metabolism to Alzheimer's disease pathogenesis. His work has established critical connections between dietary components, lipid homeostasis, and amyloid-beta processing. With an h-index of 36 and over 3,500 total citations, his research has significantly advanced understanding of how nutritional interventions might prevent or mitigate Alzheimer's disease progression. Key areas of investigation include fatty acid metabolism, vitamin effects on neurodegeneration, and lipidomics approaches to understanding Alzheimer's disease mechanisms. His most recent publications demonstrate a continued focus on lipidomics, fatty acid metabolism, and nutritional interventions in Alzheimer's disease. The research shows promising connections between specific dietary components and amyloid-beta degradation pathways, with potential implications for therapeutic development. His work on the LipiDiDiet clinical trial represents a significant contribution to understanding how multinutrient formulations might affect cognitive decline in prodromal Alzheimer's disease. Research prize in 2010 Summa cum laude for PhD Multiple patents related to Alzheimer's disease treatment Extensive publication record with over 3500 citations Beyond his research and teaching responsibilities, Prof. Grimm provides advisory services in nutritional counseling and therapy and is involved in establishing a nutritional counseling center. He maintains an active research laboratory that operates as part of the German Institute for Dementia Prevention, providing opportunities for student involvement and continuing his groundbreaking work at the intersection of nutrition and neurodegenerative disease.