جست‌وجوی استاد و پژوهشگر

Richard J M Cowardمشاهده پروفایل

استاد

• Kidney Cell Function
• Diabetic Nephropathy
• Haemolytic Uraemic Syndrome (HUS)
• +۳ مورد دیگر

Professor Richard J M Coward is the Professor of Renal Medicine at the University of Bristol and a Consultant Paediatric Nephrologist at Bristol Royal Hospital for Sick Children. His work bridges clinical practice and research, focusing on kidney cell signaling pathways in disease. Research interests include: Understanding podocyte biology and proteinuria in kidney failure Diabetic nephropathy mechanisms and therapies Haemolytic Uraemic Syndrome (HUS) in children Inherited kidney stone disease (cystinuria) Scientific awards : MRC Clinician Scientist Fellowship (2006-2013) MRC Senior Clinical Fellowship (2013-2018) Senior Clinical Scientist Fellow (MRC) Training Initiatives : Co-director of the Wellcome Trust-funded GW4 Clinical Academic Training scheme, mentoring over 35 Fellows. Leadership roles in REF submissions and national pediatric nephrology research. International teaching collaborations in East Africa and DRC.

Daria Ilatovskayaمشاهده پروفایل

دانشیار

• Cardiorenal pathophysiology
• Ion channel biophysics
• Mitochondrial bioenergetics
• +۳ مورد دیگر

Dr. Daria Ilatovskaya is a tenured Associate Professor of Physiology at the Medical College of Georgia, Augusta University where she also serves as Graduate Program Director for the Physiology Graduate Program. She leads the Kidney and Hypertension Research Group and has adjunct roles in The Graduate School. Education: Ph.D. Cellular Biology, Institute of Cytology, Russian Academy of Sciences, 2012 M.S. Physics, Peter the Great Saint Petersburg Polytechnic University, 2009 B.S. Physics, Peter the Great Saint Petersburg Polytechnic University, 2007 Research Focus: Dr. Ilatovskaya’s laboratory integrates in vivo, ex vivo and in vitro approaches to dissect how ion channels, mitochondrial bioenergetics and sex hormones govern cardiorenal homeostasis. Areas of emphasis include: Salt-sensitive hypertension and blood pressure control Polycystic kidney disease (ARPKD & ADPKD) Mitochondrial dysfunction in podocytes and tubular epithelia Sex-specific pathobiology and precision medicine Her team employs state-of-the-art techniques such as single-channel electrophysiology on freshly isolated nephron segments, live-cell confocal imaging, high-resolution mitochondrial respirometry and chronic blood-pressure telemetry. Publication Impact: Across 93 scholarly outputs (h-index 29), her 2024–2025 portfolio reveals a surge in translational studies elucidating ANP-mediated mitochondrial protection, sex-specific redox control of podocytes, and community-based hypertension interventions in rural Georgia. Awards & Honors: Outstanding Early Career Basic Science Faculty Award, Augusta University (2025) Young Investigator Award, APS Renal Section (2024) Lazaro J Mandel Young Investigator Award (2019) FAHA distinction, American Heart Association (2018) Edward J. Lennon Award for Outstanding Woman Postdoc (2014) Funding & Mentorship: Dr. Ilatovskaya is PI or Co-I on five active NIH grants totaling >$4 million, including two NHLBI R01s investigating ANP signaling and women’s cardiovascular health. She mentors graduate students, postdocs and undergraduates, and champions diversity through CUR’s STR program. Laboratory & Team: The Ilatovskaya Lab (Lab CA-3091) currently includes an Assistant Scientist (track), senior research assistant, three graduate students and an honors undergraduate, fostering an inclusive environment centered on rigorous science and trainee success.

• Pediatrics
• Immunology
• Developmental Biology
• +۳ مورد دیگر

Dr. Jana-Christin Abt serves as a Physician Scientist at the University Medical Center Hamburg-Eppendorf (UKE) within the Medical Faculty's Department of Pediatrics and Adolescent Medicine. Her clinical and research activities focus on pediatric medicine, integrating laboratory investigations with patient care in Hamburg, Germany. Her research spans immunology and developmental biology, with significant contributions to understanding podocyte function in the complement system and developing stem cell-based platforms for developmental toxicity screening. Key areas include nephrology, reproductive toxicology, and molecular mechanisms of pediatric diseases, reflecting interdisciplinary work connecting basic science with clinical pediatrics. Abt's publications demonstrate expertise in complement biology and high-throughput screening methodologies, though specific advising roles, grants, or laboratory teams aren't documented in the available materials. Her work aligns with UKE's research priorities in neuroscience and immunology networks.

• Genetics
• Genomics
• Whole-exome sequencing
• +۶ مورد دیگر

Thomas Kitzler is a Scientist at the Montreal University Health Centre (IR-MUHC) and an Assistant Professor in the Department of Human Genetics at McGill University . His research focuses on genetic and genomic mechanisms of kidney diseases , particularly congenital anomalies of the kidney and urinary tract (CAKUT) , focal segmental glomerulosclerosis , and renal ciliopathies . Affiliations : Center for Translational Biology Child Health and Human Development Program Division of Genetics, MUHC His laboratory utilizes whole-exome sequencing , zebrafish models , and patient-derived cell systems to uncover novel disease genes and pathways. Recent publications highlight discoveries in COL4A1 , ZMYM2 , and C2CD3 mutations linked to renal and neurodevelopmental disorders. Dr. Kitzler actively contributes to genetic characterization of nephrotic syndromes and polycystic kidney diseases , with a focus on precision medicine approaches for kidney transplant recipients and circulating podocyte-toxic factors in recurrent glomerular diseases. His work demonstrates interdisciplinary integration of clinical, genomic, and functional validation methods.

Wen Liمشاهده پروفایل

دانشیار

• Space Plasma Waves
• Earth's Magnetospheric Physics
• Solar-Wind Magnetosphere Coupling
• +۲ مورد دیگر

Wen Li is an Associate Professor at the Department of Astronomy and Center for Space Physics, Boston University. With a Ph.D. from UCLA and prior research experience in atmospheric sciences, their work bridges space physics and plasma phenomena. They serve as Director of Graduate Studies, indicating leadership in academic training. Education : B.Sc., University of Science and Technology of China (2001-2005) Ph.D., University of California, Los Angeles (2005-2010) Research focuses on space plasma waves, Earth’s radiation belts, solar-wind coupling, and Jovian magnetospheres. However, recent publications reveal a shift toward immunology topics like systemic lupus erythematosus and T cell regulation, suggesting interdisciplinary exploration. Scientific Awards : Presidential Early Career Award for Scientists and Engineers (PECASE) (2025) NSF CAREER Award (2019) Alfred P. Sloan Research Fellow in Physics (2018) AGU James B. Macelwane Medal (2017) AGU Fellow (2017) Air Force Young Investigator Award (2015) Jacob A. Bjerknes Award (2009) Wen Li has mentored students and postdocs who received prestigious awards, including PECASE and AGU scholarships. Ongoing research assistant positions highlight their active role in training junior scientists.

• Nephrology
• Acute Kidney Injury
• Chronic Kidney Disease
• +۷ مورد دیگر

Roderick J. Tan serves as Associate Professor of Medicine at the University of Pittsburgh School of Medicine, with dual clinical and research leadership as Co-Director of Basic Sciences and Co-Director of the Annual Acute Kidney Injury Symposium. His clinical expertise spans Glomerular Disease, Acute Kidney Injury, Microvascular Rarefaction, and Amyloidosis, including active involvement in the University's Cardiac Amyloidosis Program. Dr. Tan's educational trajectory includes a BS from Georgetown University (1999), followed by concurrent MD and PhD degrees from the University of Pittsburgh (2007). He completed his Medicine Residency and Renal-Electrolyte Fellowship at the University of Pittsburgh Medical Center in 2010 and 2012 respectively. His research program employs a rigorous bench-to-bedside approach to unravel molecular mechanisms in kidney disease. Using conditional knockout mice and cell culture models, his lab investigates paradoxical pathway effects like the KEAP1/NRF2 system (protective against fibrosis but harmful in podocytes), renal nerve contributions to CKD progression, and microvascular rarefaction. Recent work integrates super-resolution ultrasound for noninvasive vascular assessment, demonstrating translational innovation. Analysis of his publication record (2014-2022) reveals consistent focus on molecular nephrology with increasing methodological sophistication. His work shows evolving emphasis from basic pathway characterization (Wnt/beta-catenin in fibrosis) toward clinically relevant models (renal denervation) and diagnostic tools (ultrasound imaging), while maintaining core interest in oxidative stress pathways. As an educator, Dr. Tan contributes significantly to medical and graduate curricula while mentoring trainees in his active laboratory. His dual co-director roles indicate leadership in academic program development, particularly in acute kidney injury research and basic science education. The lab provides multidisciplinary training in molecular techniques, animal models, and translational methodology. The research environment fosters collaboration across nephrology, imaging, and vascular biology, with projects spanning from fundamental cell signaling to human applications. Current initiatives on renal nerves and microvascular imaging represent frontier areas with potential to reshape CKD management strategies.

Sanna Lehtonenمشاهده پروفایل

استاد

• Diabetic Nephropathy
• Podocyte Biology
• Insulin Signaling
• +۳ مورد دیگر

Professor Sanna Lehtonen is a faculty member at the University of Helsinki , holding the position of Professor of Translational Metabolism in the Department of Pathology . She supervises doctoral programs in Biomedicine, Integrative Life Science, and Drug Research, and is affiliated with HUS Radiology and Pathology. Research Focus: Molecular mechanisms of diabetic nephropathy, podocyte dysfunction, insulin/glucose metabolism in kidney cells, and actin cytoskeleton regulation. Projects: Leading grants from Sigrid Juséliuksen Säätiö, Granatenhjelm Foundation, and others for diabetic kidney disease research. Awards: Received the Best Communication Prize at the European Diabetic Nephropathy Study Group meeting (2015). Students: Mentored Master's student Minna Karhe and doctoral candidate Satu James. Recent publications analyze integrin trafficking, adiponectin resistance, and inflammatory pathways in kidney disease, with broad keywords spanning Molecular Biology , Nephrology , and Metabolic Syndrome .

William T. Gunning IIIمشاهده پروفایل

استاد

• Bleeding disorders
• Platelet dysfunction
• Delta granule storage pool deficiency
• +۸ مورد دیگر

William T. Gunning III, Ph.D. , is a Professor of Pathology at the University of Toledo College of Medicine . He serves as Director of the Electron Microscopy Facility and maintains extensive involvement with the Microscopy Society of America , where he held the presidency in 2008. His research focuses on bleeding disorders (particularly delta granule storage pool deficiencies ), postural orthostatic tachycardia syndrome (POTS) , and medical education technology through virtual patient development. Recent work explores autoimmune mechanisms in POTS and connections between platelet dysfunction and systemic pathologies. Scientific Awards President of the Microscopy Society of America (2008) Extramural Roles Director, Electron Microscopy Facility Key contributor to platelet disorder diagnostics Dr. Gunning collaborates nationally on bleeding disorder research and has presented unpublished data at Experimental Biology 2021 . His laboratory combines electron microscopy with computational analysis to characterize platelet pathologies.

Seppo Meriمشاهده پروفایل

پژوهشگر

• Biomedical Sciences
• Complement System
• Immunology
• +۴ مورد دیگر

Seppo Meri is a Research Director at the Department of Bacteriology and Immunology, University of Helsinki, and a supervisor in the Doctoral Programmes in Biomedicine, Clinical Research, and Population Health. His research focuses on the complement system, immunology, nephrology, and infectious diseases, with a particular emphasis on diseases like C3 glomerulopathy, malaria, and rheumatoid arthritis. He has led major projects funded by the Sigrid Jusélius Foundation, Finnish Academy, and Magnus Ehrnrooth Foundation, including studies on complement dysregulation, vaccine development, and cancer progression. Projects: Juselius 2025-2028 (€73,000), Malaria Mechanisms (2025-2026), Magnus Ehrnrooth 2024-2026 (€20,000) His work explores the intersection of inflammation, complement activation, and disease mechanisms in conditions like Alzheimer’s, atherosclerosis, and post-transplant complications. Key trends include complement-targeted therapies and microbial immune evasion strategies. Scientific awards include the ECN Gold Medal (2019), Labquality Prize (2014), and membership in The Finnish Academy of Sciences (2009). He has supervised students such as Lokki, A.I. (2023-2024) and Kant, R. (2023-ongoing), while contributing to malaria control trials in Tanzania and complement research in rare diseases.

• Biochemical analysis of lipids
• Isolation and structural characterization of micro-constituents extracted from foods of the Mediterranean Diet
• Study of anti-inflammatory and anti-oxidative effects of micro-constituents in vitro and in cell cultures
• +۱ مورد دیگر

Elizabeth Fragopoulou serves as Assistant Professor of Biological Chemistry of Natural Products at Harokopio University of Athens, where her research bridges nutritional biochemistry and health sciences through investigations of Mediterranean Diet components. Her academic credentials include: B.Sc in Chemistry, University of Athens (1998) M.Sc in Biochemistry, University of Athens (2000) PhD in Biochemistry, University of Athens (2004) Dr. Fragopoulou's research program centers on: Biochemical analysis of dietary lipids and micro-constituents Structural characterization of Mediterranean Diet compounds Anti-inflammatory and antioxidant mechanisms in cellular models Platelet-Activating Factor (PAF) metabolism in disease states Her work demonstrates how wine-derived phenolics and other dietary components modulate cardiovascular and renal pathways. Analysis of her 15-year publication trajectory (2002-2017) reveals evolving expertise from structural characterization of wine compounds toward mechanistic studies of PAF enzymatic regulation and cellular protection. Key themes include the cardioprotective effects of wine polyphenols, PAF's role in diabetic complications, and molecular interactions of acetylated phenolic derivatives. Her laboratory conducts advanced biochemical and cell-based research on dietary bioactives, with emphasis on translational applications for chronic disease prevention. Contact: efragop@hua.gr | +30-2109549429 (Laboratory A).

Caroline Hadadمشاهده پروفایل

مدرس

• Sustainable Chemistry
• Nanomaterials
• Polymer Chemistry
• +۷ مورد دیگر

Dr. Caroline Hadad is a Lecturer at Université de Picardie Jules Verne, affiliated with the Glycochemistry and Agroresources Laboratory of Amiens UR 7378 LG2A. Her research focuses on sustainable chemistry approaches for materials development, with particular expertise in biopolymers, nanomaterials, and green chemistry processes that bridge fundamental science with practical applications in agriculture, biomedicine, and environmental remediation. Dr. Hadad's research interests span three main areas: π-conjugated molecules : Developing symmetrical and asymmetrical organic compounds for optoelectronic applications through Sonogashira-type coupling reactions with pyrimidine or pyridazine units Surface functionalization of carbon nanostructures : Modifying fullerenes, carbon nanotubes, and graphene to improve solubility and enable applications in nanomedicine and biotechnology Valorization of agroresources : Creating value from biomass through glycodendrimer synthesis, cellulose nanocrystals, and sustainable extraction processes for chitin and lignin Her recent publication record demonstrates a strong focus on sustainable solutions using ionic liquids and deep eutectic solvents as green processing media. Dr. Hadad has developed innovative approaches including the CoffeeCat process for lignin extraction, novel chitin deacetylation methods, and eco-friendly coatings for agricultural applications that reduce food waste. Her work consistently bridges fundamental chemical research with practical sustainability outcomes. Dr. Hadad has published extensively in high-impact journals including: International Journal of Biological Macromolecules RSC Sustainability Journal of Molecular Liquids Green Chemistry Carbohydrate Polymers Nano Research ACS Applied Materials & Interfaces Her research program demonstrates successful grant funding through consistent publication output across multiple sustainability-focused areas. Dr. Hadad collaborates with researchers across chemistry, materials science, and environmental disciplines, suggesting a well-integrated research program with both academic and potential industrial connections. She supervises research in the Glycochemistry and Agroresources Laboratory, which focuses on developing sustainable chemical processes and materials from renewable resources with applications spanning agriculture, biomedicine, and advanced materials development.

• Vascular Biology
• Lung Development and Regeneration
• Mechanobiology
• +۴ مورد دیگر

Dr. Tadanori Mammoto is an Associate Professor in the Department of Pediatrics at the Medical College of Wisconsin, with a Divisional focus in Neonatology. He is also a member of the Cardiovascular Research Center, reflecting his interdisciplinary research approach spanning vascular biology, lung development, and mechanobiology. Dr. Mammoto's research focuses on the molecular mechanisms underlying vascular development and disease, with particular emphasis on how mechanical forces and extracellular matrix properties regulate cellular behavior. His work has significantly advanced understanding of the YAP/TAZ signaling pathway, Twist1 transcription factor, and angiopoietin-Tie2 system in lung vascular development and regeneration. His laboratory investigates how these pathways contribute to conditions such as pulmonary hypertension and impaired lung development in neonates. Analysis of Dr. Mammoto's publication record reveals a consistent trajectory of high-impact research, with numerous publications in top-tier journals including Nature, Science, and Nature Medicine. His work demonstrates strong translational potential, particularly in developing novel approaches for lung regeneration and understanding vascular complications in neonatal diseases. The increasing focus on organ-on-a-chip technology in recent years reflects his commitment to innovative methodologies for studying human vascular biology. Dr. Mammoto's research has been widely recognized, with several publications receiving hundreds of citations. His work on soluble endoglin in preeclampsia (2006) has been particularly influential, with over 1,600 citations, demonstrating the broad impact of his contributions to vascular biology. His collaborative approach is evident through extensive co-authorship with researchers at Harvard Medical School and affiliated institutions, particularly with Dr. Akiko Mammoto and Dr. Donald Ingber. This collaboration has produced groundbreaking work in organ-on-a-chip technology and vascular mechanobiology, bridging engineering and medical sciences to address complex biological questions. Dr. Mammoto's laboratory represents a dynamic research environment focused on understanding fundamental mechanisms of vascular development while developing innovative approaches to model and potentially treat vascular diseases affecting neonates and adults alike.

Friedhelm Hildebrandtمشاهده پروفایل

استاد

• Pediatric Nephrology
• Genetic Kidney Diseases
• Recessive Single-Gene Disorders
• +۷ مورد دیگر

Friedhelm Hildebrandt is a Professor of Pediatrics and Ophthalmology at Harvard Medical School and a leading researcher in pediatric nephrology at Boston Children's Hospital. As an investigator of the Howard Hughes Medical Institute (HHMI), he directs a highly productive research laboratory focused on identifying the genetic causes of kidney diseases in children. His work bridges basic science and clinical applications, with a particular emphasis on translating genetic discoveries into improved diagnostics and potential treatments. Dr. Hildebrandt received his MD from Marburg University Medical School and completed internships and residency at Marburg University Medical School and Heidelberg University in Germany, as well as Middlesex Hospital Medical School in London. He furthered his training with postdoctoral research at Yale University. His educational background has provided a strong foundation for his career in both clinical medicine and research. His research primarily focuses on the identification and functional characterization of recessive single-gene causes of kidney diseases in children. His laboratory has identified more than 30 novel kidney disease genes, significantly advancing our understanding of genetic kidney disorders. He has developed efficient methods for gene identification using whole exome resequencing and other highly-parallel sequencing techniques. Since 2000, Dr. Hildebrandt has performed 'experimental' mutation analysis in single-gene renal diseases worldwide for more than 5,000 pediatric patients, establishing himself as a global authority in the field. Analysis of his recent publications reveals a consistent focus on identifying novel genetic causes of kidney diseases, with particular emphasis on congenital anomalies of the kidney and urinary tract (CAKUT) and steroid-resistant nephrotic syndrome. His work increasingly incorporates advanced genomic techniques like trio exome sequencing and copy number variant analysis, while also exploring the functional consequences of genetic variants through animal models and molecular studies. A notable trend is the growing emphasis on translating genetic findings into potential therapeutic approaches, as evidenced by studies examining treatment response to anti-proteinuric therapies based on genetic profiles. E. Mead Johnson Award in Pediatric Research (APS/SPR) Howard Hughes Medical Institute (HHMI) Investigator Member of the American Association of Physicians (AAP) Member of the German Academy of Sciences (Leopoldina) Dr. Hildebrandt has secured substantial research funding to support his investigations into the genetic basis of pediatric kidney diseases. His laboratory serves as a training ground for numerous postdoctoral fellows and graduate students, many of whom have gone on to establish independent research careers. The lab maintains active collaborations with researchers worldwide, facilitating the identification of rare genetic variants through international patient cohorts. His work has established critical connections between DNA damage repair pathways and chronic kidney failure, opening new avenues for potential therapeutic interventions. Current research directions include developing quantitative phenotyping methods for animal models to support gene replacement studies and exploring the potential for genotype-guided treatments for children with genetic kidney diseases.

Ankana Dagaمشاهده پروفایل

عضو هیئت علمی

• Pediatric Nephrology
• Genetic Kidney Disorders
• Nephrotic Syndrome
• +۴ مورد دیگر

Ankana Daga, MBBS, is an Attending Physician in the Division of Nephrology at Boston Children's Hospital and holds the academic rank of Instructor in Pediatrics at Harvard Medical School. She provides clinical care across multiple locations including Boston, Lexington, and Waltham, specializing in pediatric kidney disorders. Education: MBBS: Government Medical College, Surat, India (2010) Residency: Albert Einstein Medical Center, Philadelphia, PA (2015) Fellowship: Boston Children's Hospital, Boston, MA (2018) Research Focus: Dr. Daga's work centers on genetic and clinical aspects of pediatric nephrology. Her primary interests include steroid-resistant nephrotic syndrome, congenital anomalies of the kidney and urinary tract (CAKUT), lupus nephritis, and precision medicine approaches to kidney disease. She utilizes genomic sequencing and multicenter cohort studies to identify novel therapeutic targets and improve diagnostic accuracy. Publication Analysis: Her 15 most recent publications (2019-2025) demonstrate a strong emphasis on genetic determinants of kidney diseases, clinical management of lupus nephritis, and innovative nephrology care models. Recurring themes include exome sequencing applications, treatment outcome studies, and global health perspectives on pediatric kidney disorders. Clinical & Team Engagement: As part of Boston Children's top-ranked Nephrology Division, Dr. Daga contributes to programs including the Kidney Genetics Clinic and participates in research consortia like the Pediatric Nephrology Research Consortium. The division is internationally recognized for expertise in complex pediatric kidney conditions and cutting-edge translational research.