جست‌وجوی استاد و پژوهشگر

• Translational Pharmacology
• Drug Discovery
• Metabolomics/Lipidomics
• +۳ مورد دیگر

Dr. Stan Louie is a Professor of Clinical Pharmacy at the University of Southern California (USC) School of Pharmacy, affiliated with the Ginsburg Institute of Biomedical Therapeutics. His research focuses on translational pharmacology, leveraging metabolomics and lipidomics to identify drug targets for neurodegenerative diseases, inflammation, and regenerative therapies. Dr. Louie has advanced four therapeutic modalities from preclinical stages to clinical evaluation, with a particular emphasis on Alzheimer’s disease, retinal degeneration, and traumatic brain injury (TBI). His academic training and career are rooted in clinical pharmacy, with a strong emphasis on drug discovery and development. Key research interests include the role of bioactive lipids in neuroinflammation, the impact of APOE4 genotype on brain metabolism, and the development of targeted therapies using antibody-drug conjugates and nanoparticle systems. Dr. Louie’s recent work highlights innovations such as transcorneal electrical stimulation for retinal neuroprotection, hydroxypropyl-β-cyclodextrin barriers for antiviral delivery, and omega-3 fatty acid supplementation in TBI patients. His lab also explores the mechanistic links between lipid metabolism, inflammation, and disease progression in conditions like alcoholic hepatitis and liver cancer. His awards include Fellowships from the American and California Societies of Health System Pharmacists (2000 and 1998, respectively), the Rho Chi Honor Society (1985), and a March of Dimes Research Fellowship (1979–1982). His research has been published in high-impact journals such as *Nature Communications*, *ACS Chemical Neuroscience*, and *Molecular Cancer Therapeutics*. Dr. Louie’s translational efforts bridge basic science and clinical application, with a focus on preclinical and early-phase clinical trials. His lab collaborates on projects involving drug delivery systems, biomarker discovery, and the optimization of therapeutic strategies for chronic and acute conditions.

Ryan Schottمشاهده پروفایل

استادیار

• Vision Biology
• Molecular Evolution
• Comparative Genomics
• +۴ مورد دیگر

Ryan Schott is an Assistant Professor in the Department of Biology at York University, affiliated with the Centre for Vision Research and the Connected Minds initiative. His research focuses on understanding how vertebrate visual systems evolve and adapt to environmental pressures, combining comparative genomics, transcriptomics, and experimental approaches. He leads the Schott Lab, which explores topics such as photoreceptor evolution, fossorial adaptation, and developmental mechanisms in amphibians, squamates, and turtles. His work integrates ecological, genetic, and developmental perspectives to address questions about visual system diversification. Current projects include studying visual evolution in amphibians, the molecular basis of novel photoreceptor types, and convergent adaptations in fossorial vertebrates. Schott collaborates internationally with experts in evolutionary biology, genomics, and ecology. Publications highlight his contributions to understanding opsins, lens morphology, and retinal adaptations across species. He is active in training graduate and undergraduate students, offering opportunities in evolutionary and developmental research. His lab also develops bioinformatic tools for genomic analyses.

Alexander Borstمشاهده پروفایل

استاد

• Neuroscience
• Computational Neuroscience
• Neural Circuits
• +۵ مورد دیگر

Prof. Dr. Alexander Borst is Director of the Department "Circuits - Information - Models" at the Max Planck Institute for Biological Intelligence in Martinsried, Germany. His research focuses on understanding neural computation in the visual system of Drosophila, particularly how direction-selective motion detection circuits process visual information to guide behavior. Education: Diploma in Biology, University of Würzburg (1981) Doctoral thesis with Martin Heisenberg, University of Würzburg (1984) Habilitation and private lecturer, University of Tübingen (1989) Prof. Borst's research employs a multidisciplinary approach to investigate neural information processing at the level of individual neurons and small circuits. His department uses the fruit fly Drosophila as a model system due to its computationally tractable visual system, with circuits containing fewer than 100 neurons that can be genetically manipulated and observed. The research integrates anatomical reconstructions, physiological characterization, behavioral analysis, and computational modeling to build a comprehensive understanding of visual processing. Analysis of Prof. Borst's recent publications reveals a consistent focus on motion vision mechanisms in Drosophila, with particular emphasis on directional selectivity, neural circuit organization, and the molecular basis of visual processing. His work demonstrates how specific subpopulations of T4 and T5 cells are directionally tuned to cardinal directions and how ON and OFF pathways segregate motion processing. The publications highlight the integration of experimental techniques like 2-photon calcium imaging with computational modeling to understand circuit function. Scientific Awards: Valentino Braitenberg Award in Computational Neurobiology (2014) FENS Award (2014) Member of the HHMI Scientific Advisory Board (2018) Member of the Bavarian Academy of Sciences (2012) EMBO Member (2011) Member of the German Academy of Sciences Leopoldina (2011) Human Frontier Science Program (HFSP) Prize (2006) Prof. Borst has led his department since 2001, first at the Max Planck Institute of Neurobiology and now at the Max Planck Institute for Biological Intelligence. His research has been supported by numerous grants from German and international funding agencies. He has mentored many students and postdoctoral researchers who have established successful careers in neuroscience. His department includes multiple research groups focusing on different aspects of neural computation in the Drosophila visual system. His laboratory comprises several specialized teams working on neurogenetics, molecular characterization, electrophysiology, 2-photon functional imaging, tethered and free behavior analysis, and computational modeling. These teams collaborate closely to investigate how visual information is processed from photoreceptors to behavioral output, with particular focus on motion detection circuits and their developmental and molecular underpinnings.

• Structural Biology
• X-ray Crystallography
• Protein-Ligand Interactions
• +۳ مورد دیگر

Prof. Dr. Renu Batra-Safferling is a structural biology researcher at the Institute of Plant Biochemistry (IPB) within the Faculty of Mathematics and Natural Sciences at Heinrich Heine University Düsseldorf . Her work focuses on protein structure-function relationships through X-ray crystallography and biophysical analysis, particularly in signaling components of visual transduction pathways and LOV-family blue-light photoreceptors. Research Areas: Structural biology of signaling proteins, protein-ligand interactions, photoreceptor dynamics, and natively unfolded protein characterization. Techniques: X-ray crystallography, site-directed mutagenesis, transient/steady-state kinetics, dynamic light scattering, and CD spectroscopy. Her recent publications investigate phospholipase A mechanisms in Pseudomonas aeruginosa , LOV protein dark recovery kinetics, chemokine CCL16 dynamics, and arrestin activation via phosphorylated peptides. Collaborative work spans enzymology, photoreceptor biophysics, and protein aggregation studies. Students: Master student Lisa Jungbluth and Bachelor student Leon Hennecke Email: r.batra-safferling@fz-juelich.de

Takashi Ishikawaمشاهده پروفایل

استاد

• Structural Biology
• Cryo-electron Tomography
• Flagella/Cilia Research
• +۴ مورد دیگر

Professor Takashi Ishikawa is a distinguished researcher and Group Leader at the Paul Scherrer Institute (PSI) in Switzerland, where he heads the Laboratory for Multiscale Bioimaging within the PSI Center for Life Sciences. His work focuses on the structural biology of eukaryotic flagella and cilia using advanced electron cryo tomography and microscopy techniques. Dr. Ishikawa's research program centers on understanding the 3D molecular architecture and functional mechanisms of flagellar/ciliary components, particularly dynein motor proteins. His laboratory employs cutting-edge cryo-EM methodologies to visualize biological macromolecules and organelles in their native hydrated states, enabling three-dimensional reconstructions at increasingly higher resolutions. The team's work has revealed critical insights into the molecular arrangement of dyneins and other proteins on microtubule doublets, the structural basis of dynein power stroke, and the mechanisms underlying flagellar/ciliary bending motion. His research has significant implications for understanding ciliopathies—diseases caused by defects in flagella/cilia—which affect multiple organ systems including respiratory tracts, reproductive systems, and the brain. The fundamental insights gained from studying these natural nanomachines also inform the development of artificial nanoscale devices and systems. Dr. Ishikawa has established numerous collaborative research projects with groups across various disciplines, including biochemistry, biophysics, and medical research. His laboratory serves as a hub for structural biology research at the intersection of cell biology and nanotechnology, training the next generation of scientists in advanced imaging techniques.

Nancy J. Philpمشاهده پروفایل

استاد

• Retinal Metabolism
• Monocarboxylate Transporters
• Retinal Pigment Epithelium
• +۵ مورد دیگر

Nancy J. Philp, PhD, serves as Professor in the Department of Pathology & Genomic Medicine at Thomas Jefferson University and Associate Dean for PhD & MD/PhD Programs within the Jefferson College of Life Sciences. She earned her PhD from the University of Michigan in 1995. Dr. Philp's research investigates metabolic homeostasis in the retina, specializing in monocarboxylate transporters (MCTs) and CD147 within the retinal pigment epithelium (RPE). Her laboratory employs genetic, biochemical, and imaging techniques to study how MCTs facilitate lactate transport between Müller glial cells and photoreceptors, with discoveries including MCT3's basolateral expression in RPE. Current projects examine tissue-specific trafficking of transporter proteins, MCT12's role in cataract formation, SLC16A8 regulation in aging, and tissue factor's dual functions in oxidative stress and epiretinal membrane development. As Associate Dean, she oversees graduate education programs while leading a research laboratory focused on retinal metabolism and transporter biology.

• Ophthalmology
• Biomedical Engineering
• Stem Cell Biology
• +۵ مورد دیگر

Mark S. Humayun is a University Professor at the University of Southern California (USC), holding joint appointments in the Keck School of Medicine and the Viterbi School of Engineering. He serves as Director of the USC Ginsburg Institute for Biomedical Therapeutics and Co-Director of the USC Roski Eye Institute. His expertise lies at the intersection of ophthalmology, biomedical engineering, and stem cell biology. Humayun earned his MD from Duke University and PhD from the University of North Carolina, Chapel Hill. He pioneered the Argus II retinal implant, the first FDA-approved bionic eye for restoring vision in the blind, for which he received the National Medal of Technology and Innovation (2016). His research focuses on retinal prosthetics, stem cell therapies, and non-invasive neurostimulation techniques. Key contributions include advancements in ultrasound-based vision restoration and bioengineered retinal implants. Humayun has over 300 publications and 140 patents, with awards such as the IEEE Medal for Innovations in Healthcare Technology (2020) and ARVO Fellow (2022). His work bridges clinical practice and engineering, addressing retinal degeneration and macular diseases through innovative technologies. Notable achievements include leading the development of the Argus II, which has restored partial vision to patients with retinitis pigmentosa. Current research explores next-generation implants, stem cell-derived RPE therapies, and ultrasonic stimulation for broader vision restoration. His interdisciplinary teams collaborate across engineering, computer science, and medicine to tackle complex ophthalmic challenges.

• Neurobiology
• Ophthalmology
• Physiology
• +۴ مورد دیگر

Jimmy Zhou is a Professor at Yale University School of Medicine, with joint appointments in the Departments of Cellular and Molecular Physiology and Neuroscience. His research focuses on retinal neurobiology, investigating synaptic circuits, neurotransmitter systems, and developmental mechanisms in visual processing. PhD, University of Houston (1989) MSc, University of Houston (1984) BS, Fudan University (1982) Dr. Zhou's work spans retinal physiology, direction selectivity in starburst amacrine cells, contrast processing, and the role of vGluT3 amacrine cells in retinal circuits. He explores how spontaneous retinal activity shapes visual map development and contributes to retinal degeneration models. His recent publications (2015-2023) highlight vGluT3 amacrine cell circuits, retinal wave dynamics, optogenetic techniques, and cone-rich retinal organoids. Key themes include neurotransmitter co-release, synaptic integration, and retinal disease modeling. Dr. Zhou leads research supported by NIH grants (e.g., Vision Core Grant renewal in 2022) and mentors through Yale's academic programs. His lab investigates retinal networks at the intersection of neuroscience and biomedical data science.

Jeremiah Limمشاهده پروفایل

مدرس ارشد

• Biomarkers
• Ocular imaging
• Electroretinography
• +۷ مورد دیگر

Jeremiah Lim is a Senior Lecturer at the School of Allied Health within the Department of Optometry and Vision Science at The University of Western Australia. He holds a PhD in Neuroscience from the University of Melbourne, specializing in Alzheimer’s disease ocular phenotypes, and has additional qualifications in optometry and education. His research focuses on neurodegenerative diseases (Alzheimer’s/Parkinson’s), retinal imaging , and biomarkers , with particular emphasis on translating ocular findings to broader neurological insights. Key projects include retinal hyperspectral imaging in disease models and improving eye health literacy in disadvantaged communities. Recent work emphasizes mouse models for studying neurodegeneration, electrophysiology , and gene therapy applications. Lim has authored over 25 peer-reviewed articles, with notable contributions to retinal biomarker development and clinical optometry practices. Awards: Alexander-Guelma Clinical Fellow in Neuroscience (2019), Eberhard Dodt Memorial Award (2016) Grants: Perth Eye Foundation (2024–2027), Diabetes Research Foundation of WA (2024–2025) His interdisciplinary approach bridges optometry, neuroscience, and clinical practice, aiming to advance early disease detection and patient care strategies.

• Chronobiology
• Lighting Science
• Sleep Research
• +۳ مورد دیگر

Oliver Stefani is a Senior Research Associate at the Lucerne School of Engineering and Architecture (HSLU) within the Institute of Building Technology and Energy. His work focuses on the intersection of light exposure, circadian rhythms, and human health. He holds a Dr.-Ing. in Mechanical Engineering and has extensive experience in research roles spanning over two decades, including postdoctoral work at the University of Basel's Center for Chronobiology and leadership positions in visualization and lighting laboratories. Education: Dr.-Ing. (Maschinenbau), Lucerne School of Engineering and Architecture Studium Investitionsgüter-Design, Staatliche Akademie der Bildenden Künste Stuttgart Feinwerktechnik, GSO Fachhochschule Nürnberg Research Interests: Chronobiology, lighting science, melatonin regulation, circadian rhythm disruption, and the health impacts of light exposure in both natural and built environments. His work often explores wearable light-logging technology, daylight simulation, and evidence-based lighting standards. Recent Work Trends: Recent studies emphasize light's role in metabolic health, post-COVID-19 circadian hygiene, and the development of standardized lighting metrics. Collaborative projects include international efforts to improve light exposure reporting in sleep research. Awards & Affiliations: Member of the Swiss Light Society Executive Board, CIE JTC 20 Wearable Light Dosimetry committee, and jury member for Prix Lumiere and Lichtkulturrat. Active in the Good Light Group promoting health-conscious lighting practices. Advising & Grants: Leads research projects such as the IGE Innovationswettbewerb 2025/2024. His work is supported through institutional funding and collaborative grants with universities and industry partners. Labs & Teams: Formerly led the Visualization Lab at Basel's Center of Advanced Technologies and contributed to the Fraunhofer IAO's Light Fusion Lab. Currently oversees projects at HSLU's IGE Center for Integrated Building Technology.

Michelle A. Whaleyمشاهده پروفایل

استاد آموزشی

• Cellular & Molecular Biology
• Infectious & Vector-Borne Diseases
• Neuroscience & Behavior
• +۵ مورد دیگر

Michelle A. Whaley is a Teaching Professor in the Department of Biological Sciences at the University of Notre Dame, where she has been an influential educator and researcher since 1993. She holds a Ph.D. from the University of Notre Dame and a B.S. from Scripps College. Her roles include faculty coordinator of the Undergraduate Research program and the Alumni Mentor program, and she previously served as Assistant Department Chair (2014–2019) and REU Program Director (1999–present). Teaching Professor, University of Notre Dame (2011–Present) Associate Teaching Professor (2001–2011) Assistant Teaching Professor (1993–2000) Ph.D., University of Notre Dame B.S., Scripps College Her research centers on the cellular and molecular basis of vision in mosquitoes, particularly Aedes aegypti and Anopheles gambiae , focusing on rhodopsin regulation, gene expression, and light-evoked behaviors. She uses transgenic Drosophila models to study mosquito genes and collaborates extensively with Dr. Joseph O'Tousa. Her work bridges genetics, neuroscience, and infectious disease research, with strong emphasis on undergraduate involvement. The recent publications (2012–2022) reflect a sustained focus on visual gene function in mosquitoes, especially rhodopsin dynamics and light-mediated behavior. These studies combine molecular biology, genetics, and neuroethology, contributing to broader efforts in vector-borne disease control. Her educational scholarship includes curriculum reform in introductory biology, promoting inquiry-based and research-integrated learning. Her scientific honors include: Indiana Professor of the Year (2014) Edmund P. Joyce, CSC, Award for Excellence in Undergraduate Teaching (2014) Arthur Quigley, PhD Award for community service and education (2012) Michelle Whaley is deeply committed to student mentorship, having advised numerous undergraduate researchers and directed the REU program for over two decades. She teaches research-intensive courses such as the CRISPR Research Experience and Classical and Molecular Genetics Laboratory, and she leads the Graduate Student Teaching Apprenticeship Program. Her educational leadership extends to curriculum development, including co-chairing the committee to reimagine introductory biology and serving as Faculty Fellow at the Institute for Educational Initiatives. She is actively involved in several educational and research teams, including the Jordan Research Teams and the Molecules to Ecosystems introductory biology initiative, fostering collaborative, interdisciplinary learning environments.

Rajesh Raoمشاهده پروفایل

دانشیار

• Ophthalmology
• Oncology
• Stem Cell Research
• +۴ مورد دیگر

Rajesh Rao is an Associate Professor in the Department of Ophthalmology and Visual Sciences at the University of Michigan. His work spans ocular oncology, retinal diseases, and stem cell biology, with a focus on translational applications. Key Research Areas: Vitreoretinal lymphoma diagnostics using liquid biopsy Stem cell therapies for age-related macular degeneration (AMD) Role of MYD88 L265P mutation in ocular CLL diagnosis Quiescence mechanisms in embryonic stem cells Collaborations: Work with Qiang Li, Hakan Demirci, Noah Brown, Bryan Betz, and others Multidisciplinary teams in ophthalmology, oncology, and stem cell research Recent publications in Nature Communications , Ophthalmology Retina , and Stem Cell Reports highlight his contributions to ocular lymphoma detection and stem cell fate regulation. No scientific awards or student advisement details were explicitly mentioned in available data.

• Neuropharmacology
• Visual Neuroscience
• Synaptogenesis
• +۵ مورد دیگر

Jean-François Bouchard is a Professor at the School of Optometry , University of Montreal , where he serves as Director. His research focuses on the role of endocannabinoids in synaptogenesis and visual system plasticity, with applications to neurodegenerative diseases and retinal disorders. Education : B.Pharm. (1994) and Ph.D. in Biochemistry/Pharmacology (2000) from University of Montreal; Postdoctoral fellowship at Montreal Neurological Institute, McGill University (2004). Research interests include: Mechanisms of synaptogenesis in the central nervous system Endocannabinoid system in retinal and visual brain function Development of therapeutic agents for congenital/traumatic neurological damage 3D imaging platforms for visual system analysis Impact of cannabis exposure on neurodevelopment Advising and grants : Supervised 18 graduate theses (2009–2024) in areas like GPR55 receptor function, retinal degeneration, and intraocular drug delivery Principal investigator for major grants from CIHR , NSERC , FQRNT , and Stem Cell Network (2005–2027), including projects on: GPR91/99 roles in CNS development (2020–2027) Delta9-THC effects on fetal neurodevelopment (2022–2026) Photoreceptor transplantation for retinal diseases (2020–2022) Labs and teams : Executive Director of GRSV (Vision Research Group) Director of Laboratoire Neuropharmacologie Member of interdisciplinary networks: CIRCA , RRSV , SNC , and GRUM

• Visual Perception
• Color Vision
• Individual Differences
• +۷ مورد دیگر

Jenny Bosten is an Associate Professor in Psychology at the School of Psychology, University of Sussex . Her research focuses on visual perception, particularly color vision and individual differences, using neuroimaging (fMRI, EEG) and psychophysics. ERC-funded project COLOURCODE (2020-2025) on cortical color representation Studied genetics of visual trait variation and anomalous trichromacy Collaborated with institutions including UC San Diego and University of Cambridge Her work explores how color perception is shaped by natural scene statistics and genetic factors. Publications address cortical encoding mechanisms, visual enhancement technologies, and ecological approaches to perception. Current teaching includes advanced neuroscience courses and supervision of MSc research projects. Professional roles include membership in the International Colour Vision Society and former Secretary of the Colour Group (Great Britain).

• Retinal Disease
• Neuroscience
• Mouse Model
• +۷ مورد دیگر

Alicia Brunet is a Research Fellow at the UWA Medical School , affiliated with the Centre for Ophthalmology and Visual Science and the Lions Eye Institute at the University of Western Australia . Her work focuses on retinal diseases and gene therapy. Current role: Research Fellow (Multi-Discipline Adjunct) Affiliation: UWA Medical School, Centre for Ophthalmology and Visual Science Research Interests Retinal Disease : Developing therapeutic approaches using cell lines like 661W Neuroscience : Studying photoreceptor and cone cell dysfunction Nanotechnology : Designing nanoparticle-based delivery systems for retinal treatments Oxidative Stress : Exploring antioxidant therapies such as probucol Genetic Disorders : Targeting inherited retinal diseases through molecular interventions Publication Trends Recent work highlights interdisciplinary approaches combining nanoparticle engineering , gene therapy , and pharmacological strategies to address retinal degeneration, oxidative stress, and visual impairment. Labs & Collaborations Active in the Lions Eye Institute , collaborating with teams on retinal disease research and nanoparticle-based therapeutics.