جست‌وجوی استاد و پژوهشگر

• Exercise Physiology
• Sports Medicine
• Cardiovascular Health
• +۳ مورد دیگر

PD Dr. Julia Maria Kröpfl is an Associate Professor at the University of Basel, holding multiple concurrent academic appointments across the Faculty of Medicine and Department of Sport, Exercise and Health (DSBG). She serves as a Lecturer in the Faculty of Medicine, Research Associate in the Department of Preventive Sports Medicine and Systems Physiology, Research Assistant (Admin) in the Department of Sport, Exercise and Health, Research Associate in the Department of Rehabilitative and Regenerative Sports Medicine, and Visiting Researcher in the Department of Biomedicine (FG Brink). Her research program centers on the molecular mechanisms of exercise physiology, with particular emphasis on stem and progenitor cell mobilization, microRNA pathways, and cardiovascular adaptations. Dr. Kröpfl has made significant contributions to understanding exercise-induced responses in heart failure patients, especially those with preserved ejection fraction (HFpEF), and has developed specialized exercise protocols for various patient populations. Her habilitation lecture in October 2024, titled 'Make your stem cells move: regeneration and disease management through physical exercise,' highlights her expertise in leveraging exercise for regenerative medicine approaches. Analysis of her 15 most recent publications reveals a strong focus on molecular exercise biology, particularly examining microRNA expression patterns (especially miR-21 and miR-126) and their role in mediating exercise benefits. Her research spans from basic molecular investigations to clinical trials, including the VascuFit studies examining vascular adaptations and the HIT-GLAUCOMA trial investigating exercise interventions for glaucoma patients. A recurring theme is identifying how specific exercise modalities can be optimized for different clinical conditions to maximize therapeutic benefits. Dr. Kröpfl appears to be actively involved in supervising doctoral candidates and participating in academic governance within her departments, though specific students are not named in the available information. Her research program bridges basic science and clinical application, with publications ranging from molecular studies of cellular mechanisms to randomized controlled trials of exercise interventions.

Inas F. Aboobakarمشاهده پروفایل

مدرس

• Ophthalmology
• Genetics
• Molecular Biology
• +۳ مورد دیگر

Inas F. Aboobakar is an Instructor in Ophthalmology at Harvard Medical School and an Investigator at Massachusetts Eye and Ear. Her research focuses on the genetic and molecular mechanisms of ocular diseases such as glaucoma, strabismus, and amblyopia, with an emphasis on multi-ethnic populations and mitochondrial biology. Harvard Medical School Instructor in Ophthalmology Massachusetts Eye and Ear Investigator Research Interests Dr. Aboobakar’s work explores the intersection of genetics, molecular biology, and ophthalmology. She investigates: Genetic risk factors for glaucoma and strabismus Mitochondrial gene expression in retinal dysfunction Non-invasive imaging techniques for early diagnosis Ancestral differences in polygenic risk prediction Publications Overview Her recent studies span genome-wide association analyses, zebrafish models of glaucoma, and biomechanical stress responses in ocular tissues. Key themes include: Hereditary and environmental interactions in eye disease Translational applications of genetic risk scores Linking systemic vascular markers to ocular pathologies Psychosomatic comorbidities of strabismus

Lih Kuoمشاهده پروفایل

استاد

• Microcirculation Physiology
• Cardiovascular Physiology
• Ophthalmic Vascular Biology
• +۳ مورد دیگر

Lih Kuo, PhD is a Regents Professor of Medical Physiology at the Texas A&M University School of Medicine. He also serves as Associate Department Head and Director of the Ophthalmic Vascular Research Program. His research focuses on microvascular regulation in coronary and retinal systems, investigating mechanisms like hemodynamic, metabolic, and neural factors. Key techniques include cell culture, molecular analysis, and mathematical modeling. Education: Bachelor of Science, Tunghai University, Taiwan (1979) Master of Science, National Taiwan University (1983) PhD in Medical Physiology, Medical College of Virginia (1987) Postdoctoral Training, Texas A&M University (1989) Research Interests: Mechanisms of vascular tone regulation in microvessels, particularly under pathophysiological conditions such as diabetes, hypertension, and ischemia-reperfusion injury. Current studies explore integrative regulation of coronary and retinal microcirculation using advanced experimental and computational approaches. Recent Research Trends: Recent work emphasizes diabetes-induced vascular dysfunction in ocular and cardiac systems. Key themes include stanniocalcin-1’s role in photoreceptor rescue, oxidative stress pathways in endothelial dysfunction, and novel peptides impacting angiogenesis. Collaborative projects combine molecular biology, pharmacology, and imaging to address clinical challenges in retinal degeneration and cardiovascular disease. Labs/Teams: Leads the Ophthalmic Vascular Research Program, focusing on translational research in ocular and cardiovascular microvascular disorders.

• Retinal Imaging
• Ocular Hemodynamics
• Diabetic Retinopathy
• +۲ مورد دیگر

Mahnaz Shahidi is Professor of Ophthalmology and Biomedical Engineering and Vice Chair for Translational Research at the University of Southern California, holding the Ralph and Angelyn Riffenburgh Professorship in Glaucoma Research. She chairs the Faculty Appointments and Promotion Tenure Committee Panel A. Her research develops optical imaging technologies to study ocular and systemic diseases, with ongoing projects including: Retinal oxygen delivery/metabolism in disease models Microvascular hemodynamics characterization Image-based biomarkers for diabetic retinopathy Retinal neurovascular coupling in glaucoma and sickle cell retinopathy She has received significant recognition including: UIC Faculty of the Year (2014) UIC Inventor of the Year (2012) Research to Prevent Blindness Senior Scientific Investigator Award (2009) Her recent publications focus on retinal oxygenation quantification, vascular physiology biomarkers, and metabolic imaging innovations, with applications to diabetic retinopathy, glaucoma, and Alzheimer's disease models.

• Cell Biology
• Virology
• Liver Pathology
• +۳ مورد دیگر

Ruomei Li is a Chief Engineer and Researcher in the Department of Medical Biology at UiT The Arctic University of Norway. Her work focuses on liver sinusoidal endothelial cell biology, viral infection mechanisms, and lipid metabolism. She actively contributes to lab maintenance, radiation safety, and training initiatives. Her research investigates cellular responses to glucocorticoids, oxidative stress, and viral pathogens. Key areas include stabilin receptor function in LDL clearance, BKPyV infection dynamics, and hepatic microvascular pathology. Li collaborates extensively with teams studying muridbetavirus entry pathways and liver fibrosis models. She has published widely in journals like Frontiers in Pharmacology , npj Gut and Liver , and PLOS ONE , with recent work addressing dexamethasone effects on endothelial cells and dynamin inhibitors' antiviral potential. Her studies bridge cellular biology, proteomics, and translational medicine. Member of Vascular Biology research group Expert in microscopy and proteomics/transcriptomics techniques Key contributor to lab safety protocols and staff training

• Microvascular Physiology
• Cerebral Blood Flow Regulation
• Neurodegenerative Diseases
• +۳ مورد دیگر

Albert Gonzales is an Assistant Professor in the Department of Physiology and Cell Biology at the University of Nevada, Reno School of Medicine. His research focuses on microvascular physiology, particularly the regulation of cerebral blood flow in Alzheimer's disease and light-sensitive mechanisms in choroid vasculature related to macular degeneration. Education: B.S. in Biology, California State Polytechnic University, Pomona M.S. in Biological Sciences, California State Polytechnic University, Pomona Ph.D. in Biomedical Science, Colorado State University, Fort Collins His work investigates how capillary microcirculation dynamically responds to tissue demands and environmental changes through calcium signaling, TRP channels, and pericyte contractility. Research spans neurovascular coupling , ocular physiology , and vascular dysfunction in neurodegenerative diseases . Publications demonstrate expertise in TRPM4 channel activity , STIM1 signaling , pericyte-mediated blood flow control , and neurodegenerative disease mechanisms . Studies range from Alzheimer's models to retinal circulation dynamics , with methodological innovations in vascular imaging and electrophysiology. The lab employs ex vivo ocular perfusion systems and calcium imaging to explore vascular responses, maintaining a focus on translational applications for neurodegenerative and ocular diseases.

Xiaohua Gongمشاهده پروفایل

استاد

• Molecular Biology
• Cell Biology
• Eye Development
• +۵ مورد دیگر

Xiaohua Gong is a Professor of Optometry and Vision Science at the University of California, Berkeley's School of Optometry. Her research focuses on molecular and cellular mechanisms underlying vertebrate eye development and diseases, particularly cataracts, retinal degeneration, and vascular disorders. She leads the Gong Lab, which employs genetic, biochemical, and imaging techniques to study lens biology, gap junction signaling, and connexin proteins' roles in ocular health. Key projects include analyzing ENU-induced mouse mutations, MAP kinase pathways in lens differentiation, and developing diagnostic tools for ocular diseases. Her teaching includes Vision Science courses 206A (Anatomy/Physiology of the Eye) and 212G (Molecular Genetics of Eye Development). Notable contributions include identifying novel genetic factors in eye development, characterizing connexin mutations' effects on cataract formation, and elucidating interactions between Eph receptors and lens morphogenesis. The lab also pioneers 3D lens cell culture systems and advanced imaging technologies like adaptive optical microscopy for in vivo studies. Awards and recognitions are not explicitly listed in the text, but her extensive publication record reflects sustained research impact. The Gong Lab fosters collaboration across disciplines, integrating molecular biology, genetics, and clinical insights to advance translational ophthalmology.

Christina Brockمشاهده پروفایل

استاد

• Autonomic Nervous System
• Diabetic Neuropathy
• Gastroenterology
• +۴ مورد دیگر

Christina Brock is a Professor at Aalborg University and Aalborg University Hospital, affiliated with The Faculty of Medicine's Department of Gastroenterology and Hepatology. She bridges clinical, academic, and life-science environments through her veterinary surgeon background and PhD in human biology. Her research focuses on the autonomic nervous system at the intersection of neurophysiology, diabetes, and gastroenterology. She established a state-of-the-art autonomic laboratory for mechanistic studies and clinical trials. Her work includes vagal nerve stimulation, GLP-1, and diabetic microvascular complications, particularly with finerenon's anti-fibrotic potential. She teaches medical students at Bachelor's and Master's levels, supervising 18 PhD and 19 Master's students. Her leadership roles include securing €3.7 million in funding, serving on NEUROdiab's executive board, and advising Harvard Medical School's Office of Global Education. Recent publications highlight her expertise in diabetic gastroenteropathy , autonomic neuropathy , and vagus nerve stimulation , with clinical trials published in Diabetes Research and Clinical Practice , Diabetologia , and Diabetes Technology & Therapeutics .

Gareth Dunseathمشاهده پروفایل

پژوهشگر

• Diabetes
• Glucose Intolerance
• Insulin Resistance
• +۴ مورد دیگر

Dr. Gareth Dunseath is a Senior Research Officer at Swansea University's School of Medicine, specializing in diabetes research. He manages the Clinical Practice and Good Laboratory facility in the Grove Building and holds a PhD in diabetes pathophysiology from Swansea University (2017). His work focuses on clinical trials in diabetes, biomarker development, and quality control of laboratory equipment. He teaches the Basics of Diabetes module for the MSc in Diabetes Practice. Education: PhD in Diabetes Pathophysiology (Swansea University, 2017). Research Interests: Glucose intolerance mechanisms, insulin resistance, beta cell dysfunction, and the validation of new diabetes diagnostics/therapies. He has led projects on closed-loop insulin systems, wearable glucose monitors, and non-invasive testing methods. Publications & Projects: Over 80 publications in journals like Diabetes Care and Nature Medicine . Grants include developing proinsulin assays and glucagon-based diagnostics. His lab evaluates medical devices like benchtop analyzers and glucose monitors. Awards: None explicitly listed, though his work has received support from Health and Care Research Wales and Welsh Government. Grants & Teams: Collaborates on clinical trials (e.g., USTEK1D trial for type 1 diabetes immunotherapy). Manages the Diabetes Research Group's lab facilities and oversees quality control standards.

Goran Petrovskiمشاهده پروفایل

استاد

• Ophthalmology
• Retinal Surgery
• Diabetic Retinopathy
• +۵ مورد دیگر

Goran Petrovski is a Professor at the Department of Ophthalmology within the Faculty of Medicine at the University of Oslo. His clinical and research activities focus on vitreoretinal surgery, diabetic retinopathy, corneal stem cell research, and glaucoma management. He maintains active collaborations across European institutions and leads research initiatives including the PerDIRe project for personalized diabetic retinopathy screening. His research spans multiple critical areas in ophthalmology including retinal disease mechanisms, surgical innovations, and health economic analyses of eye care delivery. Recent work demonstrates particular emphasis on diabetic retinopathy screening optimization, novel surgical instrumentation, corneal regeneration techniques, and epigenetic factors in ocular disease. His laboratory investigations frequently employ advanced imaging modalities, tissue engineering approaches, and translational models. Analysis of his recent publications reveals strong thematic focus on improving outcomes in retinal detachment surgery, developing less invasive glaucoma treatments, and applying AI to diabetic retinopathy screening. His work bridges basic science discoveries with clinical implementation, particularly in resource optimization for eye care services and personalized treatment approaches for complex retinal conditions. Petrovski actively contributes to multicenter European research collaborations and maintains strong clinical research ties with the Clinical Retina Research group at OUS Ullevål. His work demonstrates consistent translational focus from bench to bedside, with particular attention to practical innovations that can be implemented in routine clinical practice.

• Ophthalmology
• Retinal and Choroidal Pathology
• Optical Coherence Tomography (OCT)
• +۳ مورد دیگر

Solmaz Abdolrahimzadeh is an Associate Professor at the Department of Neuroscience, Mental Health and Sensory Organs (NESMOS) at Sapienza University of Rome, with concurrent roles as a Consultant Ophthalmologist and Tenure Track Researcher at Sant'Andrea Hospital. Her clinical and research expertise focuses on retinal and choroidal pathologies , particularly in neurodegenerative diseases and ocular manifestations of rare systemic conditions like neurofibromatosis type 1 and Sturge-Weber syndrome. Education: Medical Doctor (1989, summa cum laude ), Ophthalmology Specialty (1994, cum laude ), PhD in Cell Biology (2016, University of Kent) Key research areas: Optical Coherence Tomography (OCT) imaging, anti-VEGF therapy, choroidal vascularity, and microvascular changes in AMD, Alzheimer's, and diabetic retinopathy Her recent publications analyze choroidal vascularity indices , retinal biomarkers in neurodegenerative diseases, and predictive AI models for AMD. She serves as Associate Editor for BMC Ophthalmology and Topic Editor for the International Journal of Molecular Sciences. Scientific awards include competitive fellowships from Istituto Superiore di Sanità and Editor's Choice recognition in the British Journal of Ophthalmology . She leads multicenter trials on ocular vascular alterations and collaborates internationally, including with University Hospital Zurich.

Shahina Pardhanمشاهده پروفایل

استاد

• Diabetic Retinopathy
• Low Vision Rehabilitation
• Age-related Visual Impairment
• +۴ مورد دیگر

Professor Shahina Pardhan is a pioneering academic and clinician in optometry and vision science at Anglia Ruskin University (ARU), serving as the first female Professor of Optometry in the UK. She leads the Vision and Eye Research Institute (VERI), which has achieved 'world-leading' status in clinical and public health research. Her roles include Director of VERI, membership in the Faculty of Health, Medicine and Social Care, and School of Medicine affiliations. Her academic journey includes a First-Class Honours BSc in Optometry from the University of Bradford, a PhD on 'Summation and inhibition in binocular contrast detection' supported by the College of Optometrists, and postdoctoral research scholarships. She has supervised 17 Research Fellows and 14 PhD students, examining topics ranging from visual short-term memory to global diabetes burden analysis. Research interests focus on diabetic retinopathy, low vision rehabilitation, and age-related visual changes. Her work bridges clinical practice and public health, addressing global challenges like diabetic eye disease and health inequities. VERI collaborates with international bodies including WHO and the International Agency for the Prevention of Blindness, contributing to Global Burden of Disease studies. Key achievements include REF2014/2021 submissions with 'world-leading' scores, impactful research reaching over 110,000 people globally, and awards such as the Asian Women of Achievement Award and Ophthalmologist Power List recognition. Her media engagement includes BBC/ITV appearances and high-impact publications like BMJ articles with 347 million views. Grants: EU Horizon 2020, NIHR, Global Challenge Research Fund Editorial Boards: Ophthalmic and Physiological Optics, Journal of Personalised Medicine Leadership: Women in Vision UK network, International Agency for Prevention of Blindness working groups Labs/Teams: Directs VERI's multinational team and collaborates with institutions worldwide, including Harvard, Cambridge, and Indian research centers.

• Nitric oxide signaling
• Cardiovascular physiology
• Molecular medicine
• +۷ مورد دیگر

Professor James Leiper is an Honorary Professor in the School of Cardiovascular & Metabolic Health at the University of Glasgow, where he leads research at the Institute of Cardiovascular and Medical Sciences and the BHF Glasgow Cardiovascular Research Centre. His work focuses on translating basic science findings into applications for human health and disease, with particular emphasis on nitric oxide signaling pathways. Originally trained in molecular biology at the MRC Clinical Research Centre, Professor Leiper developed his interest in cardiovascular physiology while working with Professor Patrick Vallance in the Centre for Clinical Pharmacology at UCL. He continued this research as a Programme Leader at the MRC Laboratory for Medical Sciences before joining the University of Glasgow in 2017. Professor Leiper's research centers on understanding the mechanisms that regulate nitric oxide (NO) signaling in health and disease. His laboratory investigates how endogenously produced inhibitors of NO synthesis, particularly through the ADMA/DDAH pathway, might be harnessed therapeutically. His work spans cardiovascular, immune, and central nervous systems, with applications to conditions including hypertension, atherosclerosis, and the cardiovascular collapse seen in septic shock. Rather than directly targeting NO (which has had limited therapeutic success), his research focuses on endogenous regulatory pathways that might facilitate more appropriate regulation of NO production. His recent publications demonstrate a continued focus on nitric oxide signaling pathways, with particular attention to asymmetric dimethylarginine (ADMA) and dimethylarginine dimethylaminohydrolase (DDAH). His work spans multiple disciplines including vascular biology, cardiovascular physiology, and translational medicine, with applications to conditions such as septic shock, hypertension, metabolic disorders, and vascular contributions to dementia. Professor Leiper has secured significant research funding from major organizations including the Medical Research Council (MRC), British Heart Foundation (BHF), and Wellcome Trust, totaling millions of pounds for his research on nitric oxide signaling pathways. His research group has been supported by substantial grants including an MRC Intramural Research Programme Funding award of £2.8 million and multiple British Heart Foundation project grants. Professor Leiper has supervised numerous PhD students and postdoctoral researchers through various funding mechanisms including BHF PhD studentships, MRC Chain Florey Fellowships, and the BHF ICTEM 4-year PhD training scheme. To facilitate translation of his understanding of nitric oxide signaling for healthcare benefit, he established a biotech company backed by venture capital funding to perform clinical trials of new drugs for the treatment of septic shock. His research group collaborates extensively with clinical researchers across multiple disciplines to advance understanding of cardiovascular diseases and their treatment.

Gábor Csányiمشاهده پروفایل

استاد

• Vascular Biology
• Atherosclerosis
• Inflammation and Immunity
• +۴ مورد دیگر

Gábor Csányi, PhD, is a Professor at the Vascular Biology Center within Augusta University's Medical College of Georgia. His research focuses on understanding the molecular mechanisms underlying vascular inflammation, atherosclerosis, and oxidative stress-driven pathologies. He leads a laboratory investigating how NADPH oxidase isoforms (particularly NOX1 and NOX2), CD47-SIRPα signaling, and cellular metabolic reprogramming contribute to cardiovascular diseases. Key interests include: Macrophage foam cell formation in atherosclerosis Role of ENaC channels in lung microvascular protection Copper transport in vascular inflammation Neurofibromin-mediated regulation of retinal neovascularization SARS-CoV-2 spike protein-induced endothelial dysfunction Recent work highlights the therapeutic potential of targeting macropinocytosis pathways and CD47-SIRPα interactions to suppress atherogenesis. His group employs advanced in vivo models, pharmacological inhibitors, and genetic tools to dissect these mechanisms. Research encompasses collaborations on: COVID-19-associated vascular complications Pancreatic stellate cell activation in cancer progression Renal ischemia-reperfusion injury He oversees the Vascular Biology Center's core facilities and participates in translational studies bridging basic science and clinical cardiology. Ongoing projects aim to develop novel biomarkers and inhibitors for vascular diseases.

Tim Curtisمشاهده پروفایل

استاد

• Diabetic Retinopathy
• Vascular Physiology
• Ocular Therapeutics
• +۳ مورد دیگر

Tim Curtis is a Professor at Queen's University Belfast's School of Medicine, Dentistry and Biomedical Sciences, where he leads research on diabetic retinopathy mechanisms and novel therapeutics. His work focuses on mitochondrial dynamics, vascular physiology, and neuroprotection in ocular diseases. He serves as Academic Lead for the Advanced Imaging Core Technology Unit and has directed multiple projects on retinal endothelial dysfunction funded by organizations including Diabetes UK and Wellcome Trust. Research spans molecular pathways in diabetic retinopathy, TRP channel pharmacology, and mitochondrial quality control. Recent work investigates therapeutic targets like TRPV4 channels and mitophagy activators. Articles demonstrate consistent focus on retinal neurovascular unit protection through metabolic modulation and ion channel regulation. Professor Curtis mentors graduate students in vascular physiology, diabetic retinopathy, and ocular therapeutics. His laboratory employs interdisciplinary approaches including live-cell imaging, electrophysiology, and 3D electron microscopy to study retinal pathophysiology.