جست‌وجوی استاد و پژوهشگر

Bin Wuمشاهده پروفایل

دانشیار

• Single Molecule Imaging
• RNA Biology
• Gene Expression
• +۷ مورد دیگر

Bin Wu is an Associate Professor in the Department of Biophysics at the Johns Hopkins University School of Medicine. His research focuses on visualizing and quantifying biological processes in real time using single-molecule imaging and spectroscopy technologies in live cells, combined with theoretical modeling. He leads an active lab studying gene expression regulation, particularly the dynamics of RNA molecules during transcription, translation, trafficking, and decay. Research Interests: Single-molecule imaging of RNA and protein dynamics Real-time visualization of translation using SINAPS (Single molecule imaging of nascent peptides) Regulation of gene expression in neurons, including dendritic and axonal translation Development of optical tools to manipulate gene expression spatially and temporally Understanding translational bursting, ribosome stalling, and mRNA decay mechanisms His recent publications reveal a strong trend in probing fundamental questions in gene expression using cutting-edge imaging techniques. Work spans from basic biophysical principles of translation to disease-relevant models such as ALS/FTD involving C9ORF72 repeat expansions. A key innovation is the development of SINAPS, enabling direct observation of translation dynamics at the single mRNA level. Scientific Awards: No formal awards listed in the provided text. Advising and Grants: Actively mentors multiple graduate students, master’s students, undergraduates, and research specialists. Lab members include Leslie Watkins, Blake Nelson, Mulin Li, and others working on RNA biology and imaging. Given the high-impact publications in journals like Science , Nature Communications , and Molecular Cell , it is likely that Dr. Wu holds external research funding, though specific grants are not mentioned. Labs and Teams: Dr. Wu leads a multidisciplinary team integrating physics, biology, and computational modeling. The lab is based at the Rangos Building, Room 454, and collaborates with experts in neuroscience, genomics, and biophysics. The team develops and applies novel optical methods to address previously intractable biological questions in live systems.

Stefan Semrauمشاهده پروفایل

دانشیار

• Cell-fate Decision-making
• Single-cell Transcriptomics
• Stem Cell Biology
• +۶ مورد دیگر

Dr. Stefan Semrau is an Associate Professor at the Leiden Institute of Physics (LION) within the Faculty of Science at Leiden University . His research focuses on quantitative single-cell biology, particularly studying cell-fate decision-making using embryonic stem cells as a model system. Develops single-cell RNA-seq and single-molecule FISH methods Applies machine learning and mathematical modeling to decode stem cell differentiation Investigates interplay of epigenetics, cell cycle, and signaling molecules His work addresses both fundamental biological dynamics and applications in regenerative medicine and cancer stem cell eradication . Recent publications emphasize single-cell transcriptomics and gene fusion quantification . The Semrau Lab maintains collaborations across disciplines and develops tools like fuseFISH for cancer research. Scientific Awards FOM-Projectruimte Grant (2016) for stem cell dynamics research Advising & Collaborations Current advisees include PhD students studying retinoic acid-induced differentiation and lineage priming. The lab integrates computational and experimental approaches through partnerships with biotech and physics teams.

• Chemical Biology
• Protein Engineering
• Non-natural Amino Acids
• +۴ مورد دیگر

Dr. Marina Rubini is a permanent Assistant Professor in Chemical Biology at University College Dublin's School of Chemistry since October 2016. Prior to this position, she served as a Senior Scientist at ETH Zurich (2016), an Independent Group Leader at the University of Konstanz (2012-2016), and held postdoctoral positions at both the University of Konstanz and Technical University of Munich. PhD from Technische Universität München, Germany Dr. Rubini's research focuses on innovative approaches to protein engineering through non-natural amino acids. Her work spans several interconnected areas: developing semisynthetic methods to engineer therapeutic proteins to study post-translational modifications; synthesizing and incorporating non-natural amino acids to investigate protein folding mechanisms; engineering enzymes for biocatalysis; and creating fluorinated antifungal peptides. She has made significant contributions to understanding how proline analogues can influence protein stability and folding kinetics, with numerous publications in high-impact journals. Analysis of Dr. Rubini's recent publications reveals a strong trend toward applying chemical biology approaches to solve biomedical problems, particularly in the areas of protein therapeutics, antimicrobial development, and structural analysis. Her work often combines synthetic chemistry with biological evaluation, demonstrating translational potential. Dr. Rubini actively contributes to academic service through multiple committee memberships including the School of Chemistry Equality Diversity and Inclusion Committee, Teaching and Learning Committee, and Research and Innovation Committee (which she chaired from 2018-2021). She serves as an editor for Scientific Reports and is a member of the Royal Society of Chemistry. Her research program is supported by significant grants including the BEACON Partnership with the University of Nottingham (2019-2027), the Synthesis and Solid State Pharmaceutical Centre (2019-2025), and a project on post-translational modifications of therapeutic cytokines (2018-2021). Dr. Rubini coordinates multiple advanced modules in medicinal chemistry and chemical biology and has supervised PhD students at University College Dublin.

Elizabeth Skellamمشاهده پروفایل

استادیار

• Bioorganic Chemistry
• Biochemistry & Biosynthesis
• Chemical Biology
• +۱۰ مورد دیگر

Dr. Elizabeth Skellam is an Assistant Professor in Organic Chemistry at the University of North Texas , affiliated with the Department of Chemistry and BioDiscovery Institute . Her research focuses on the intersection of chemistry and biology, particularly in fungal natural products and their biosynthesis. Office: SRB 130 Lab: Science Research Building 104 Email: elizabeth.skellam@unt.edu Twitter: @SkellamLab Instagram: @fantastic_fungi_unt Her work explores: Biosynthesis mechanisms of fungal polyketides and cytochalasans Combinatorial biosynthesis for novel compound generation Subcellular localization of specialized metabolites Engineering fungal systems for waste valorization Diels-Alder reactions in natural product formation Marine-derived fungal biotechnology Recent publications highlight trends in: Chemical and genetic analysis of bioactive fungal metabolites Engineering heterologous systems (Aspergillus, Trichoderma, Micromonospora) Structure-activity relationships of cytochalasans and pyrrolones Phylogenetic studies of NRPS domains Sustainable production methods using plant and microbial systems Elucidation of enzymatic mechanisms in polyketide cyclization Dr. Skellam actively seeks motivated students for research at the chemistry-biology interface via email applications.

Michael Lawsonمشاهده پروفایل

استادیار

• Structural Biology
• Computational Biology
• Systems Biology
• +۵ مورد دیگر

Michael Lawson is an Assistant Professor in the Department of Chemistry and Biochemistry at the University of California, Los Angeles (UCLA), where he leads the Lawson Lab focused on eukaryotic translational quality control mechanisms. His research integrates structural, biochemical, and computational approaches to investigate ribosome-mRNA interactions and mRNA decay pathways. Dr. Lawson's research centers on how ribosomes and decay factors distinguish between normal and defective mRNAs during translation, with particular emphasis on premature stop codon diseases affecting 11% of heritable human disorders. His lab employs biochemical reconstitution , structural techniques , and biophysical assays to dissect molecular mechanisms of translational termination and mRNA surveillance. Key interests include ribosome dynamics, release factor function, and the structural basis of quality control decisions. Recent publications reveal a consistent focus on translation termination fidelity and ribosome-associated decay pathways , with significant contributions to understanding eukaryotic termination mechanisms through structural and kinetic analyses. His work bridges bacterial and eukaryotic systems to uncover fundamental principles of mRNA quality control. The Lawson Lab maintains an active mentoring program with graduate students including Michelle Thaxton, Marcella Mirabelli, Jake Cozy, Aubrey Emmi, Adrian McFarland, Izaiah Cole, and Morgan Grimes. Student achievements include CMB and CBI awards recognizing research excellence in computational and biomedical sciences. Located within UCLA's Chemistry and Biochemistry department, the lab operates as a dynamic research hub utilizing cutting-edge biochemical and structural methodologies to advance understanding of translational quality control mechanisms and their therapeutic implications.

• Biochemistry
• Organic Chemistry
• Molecular Biology
• +۳ مورد دیگر

Mrinal K. Bhattacharjee serves as Associate Professor of Chemistry and Biochemistry at Long Island University's Brooklyn campus, where he conducts research spanning molecular mechanisms of bacterial pathogens and antibiotic discovery. Previously, he held positions as Associate Research Scientist at Columbia University and Adjunct Associate Professor roles at Fordham University and Yeshiva University, establishing a career trajectory focused on microbial biochemistry and therapeutic development. His academic foundation includes B.S. and M.S. degrees from the Indian Institute of Technology (Kharagpur, India) followed by Ph.D. studies at The Ohio State University, with post-doctoral training completed at the University of Texas at Austin. This educational background underpins his dual expertise in organic chemistry and molecular microbiology. Research interests center on Biochemistry, Organic Chemistry, Molecular Biology, and Microbiology with specialized focus on periodontal pathogens like Aggregatibacter actinomycetemcomitans. His work examines bacterial conjugation mechanisms, adhesion properties, and inhibition through natural compounds including Maillard reaction products and plant-derived antibiotics. Recent investigations explore preferential killing of slow-growing bacteria by rhubarb and myrrh compounds, addressing persistent infection challenges. Publication analysis (2025-2018) reveals systematic antibiotic research covering nucleic acid synthesis inhibitors, protein synthesis disruptors, and membrane-targeting agents. His natural product studies identify compounds with unique activity against non-growing bacteria, suggesting novel approaches for antibiotic-resistant infections. The 2018 vitamin D/IVF study indicates collaborative expansion into reproductive medicine.

Christine Chowمشاهده پروفایل

استاد

• Nucleic Acid Chemistry
• Bioorganic Chemistry
• Bioinorganic Chemistry
• +۶ مورد دیگر

Christine Chow is a Professor in the Department of Chemistry at Wayne State University's College of Liberal Arts and Sciences. Her research focuses on RNA modifications and their structural-functional relationships, utilizing bioorganic, bioinorganic, and biophysical methodologies. Education: A.B., Bowdoin College, 1987 M.A., Columbia University, 1988 Ph.D., Caltech, 1992 NIH Postdoctoral Fellow, M.I.T., 1992-94 Dr. Chow's work investigates site-specific RNA modifications, particularly pseudouridines in ribosomal RNA helix 69. Her group employs platinum complexes, fluorescence spectroscopy, and mass spectrometry to probe RNA structure and develop novel antibiotics targeting drug-resistant pathogens. Recent publications highlight innovations in RNA probing techniques, metal-drug interactions, and structural characterization of RNA-ligand complexes. Her research is supported by NIH grants including 4DP7OD018427-04 and T32GM139807 , along with NSF funding CHE 1904754 . Current projects examine RNA dynamics, antibiotic-RNA interactions, and computational modeling of modified nucleobases. Scientific Awards: NIH Postdoctoral Fellowship Dr. Chow teaches advanced courses in bioorganic chemistry and biological chemistry laboratory work, contributing to graduate and undergraduate education. Her lab maintains a focus on RNA structural biology and translational applications for antimicrobial development.

Norbert Polacekمشاهده پروفایل

استاد

• Non-protein-coding RNAs
• Ribosome biology
• Translation control
• +۴ مورد دیگر

Norbert Polacek is a Full Professor of Biochemistry at the Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) at the University of Bern, Switzerland. He has served as Director of the Department from 2021-2023 and previously as Deputy Director from 2018-2020. Since 2014, he has been head of the master program in "Molecular Life Sciences" and serves as NCCR RNA & Disease Delegate for Training & Education. His educational background includes studies in Biology/Genetics at the University of Vienna (1988-1996), followed by a diploma thesis and PhD thesis in the group of Andrea Barta at the Institute of Medical Biochemistry. He completed postdoctoral work at the University of Illinois at Chicago under Alexander S. Mankin. Polacek's research focuses on non-protein-coding RNAs (ncRNAs) within large cellular RNA/protein complexes like ribosomes and vault particles. His work examines the structural, catalytic and regulatory roles of ncRNAs during ribosome functioning, translation control, and apoptosis. His group applies biochemical, genomic, and bioinformatics tools across all three domains of life (archaea, bacteria and eukarya). His recent publications reveal a strong focus on tRNA-derived fragments, ribosomal RNA expansion segments, and vault RNAs. The work spans from fundamental ribosome mechanics to cancer biology applications, showing how ncRNAs modulate translation, regulate gene expression, and influence disease processes like hepatocellular carcinoma. His notable scientific achievements include: START award from the Austrian Science Foundation (FWF) Novartis research prize for Biology Research award of the Principality Liechtenstein Polacek leads a research group focusing on three main projects: Atomic mutagenesis of the ribosome, The regulatory non-coding RNA interactome of translating ribosomes, and The elusive molecular biology of the vault RNA. His group has made significant contributions to understanding how RNA fragments regulate translation and cellular processes, including the discovery that certain RNA fragments function as stimulants rather than inhibitors in cellular machinery. The Polacek laboratory maintains active collaborations within the Swiss National Focus in Research on RNA & Disease, jointly hosted by the University of Bern and ETH Zürich, and participates in numerous international research networks focused on RNA biology.

Donatella Pontiمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Cancer Research
• Nucleolar Metabolism
• +۶ مورد دیگر

Donatella Ponti is a Researcher (RU) in the Department of Medical-Surgical Sciences and Biotechnologies at the University of Rome "Sapienza," specializing in MEDS-02/A (MED04) General Pathology. She serves as President of the Course in Childhood Neuro and Psychomotricity and is responsible for courses in Molecular Oncology and Molecular Pathology at the Medical Faculty. Her academic career spans over two decades with a permanent research position since December 2010. Dr. Ponti earned her PhD in Biochemistry from University La Sapienza di Roma (1998-2001) under Prof. D. Barra. Prior to this, she completed a School in Biotechnology (summa cum laude) at University of Rome La Sapienza and a Biological Sciences Degree (summa cum laude) from University "La Sapienza" Rome. Her research focuses on molecular mechanisms of disease, particularly nuclear and nucleolar trafficking, protein expression, and DNA manipulation. She investigates the nucleolus as a central hub in cancer proliferation, with emphasis on receptors and transcriptional factors that modulate cell proliferation through nucleolar metabolism. Her work bridges molecular biology, cancer research, and cellular signaling pathways, with particular interest in ErbB3 receptor signaling and its nucleolar localization in glioblastoma. The thematic areas of her research include Biotechnology, Molecular Biology, Biochemistry, Cell Pathology, nucleolar metabolism, immunometabolism, and ribosome biogenesis. Her publication record demonstrates a clear trajectory from fundamental molecular biology toward translational cancer research. Early work focused on ribosomal RNA processing and antimicrobial peptides, while more recent publications center on nucleolar metabolism in cancer cells, macrophage cross-talk in tumor microenvironments, and therapeutic targeting of nucleolar dysfunction. A consistent theme across her 31 publications is the exploration of non-canonical pathways involved in cancer proliferation under nucleolar control. Dr. Ponti has received recognition for her scientific contributions: DAAD Fellowship (2017) for research at Heidelberg University Award for thesis in Biotechnology from University of Rome Sapienza (1997) Member of National Register of Biologist (since 2009) As an academic advisor, Dr. Ponti has supervised numerous graduate students including Federico Forzati, Aurora Mosetti, Selenia di Rosa, and Marzia Tagliaferro. Her research has been supported by multiple competitive grants including Sapienza University funding (2015-2024), MIUR funding, and a DAAD scholarship. She currently serves as Principal Investigator for projects including "Fibrillarin and the Nucleolus in Human Macrophage Polarization" and "Nucleolar ErbB3: A NEW TARGET IN GLIOBLASTOMA." Dr. Ponti leads research in the Instrumental Laboratory at the Department of Medical-Surgical Science and Biotechnologies and has previously supervised the animal laboratory at the same department. Her laboratory investigates cellular models including cell lines and mouse models to study molecular mechanisms of disease, with particular focus on nucleolar metabolism in cancer contexts.

• Neuroscience
• RNA Biology
• Molecular Biology
• +۳ مورد دیگر

Ezgi Hacisuleyman serves as an Assistant Professor at the University of Florida's Scripps Biomedical Research campus in Jupiter, FL, where she directs the Hacisuleyman Lab focused on RNA-centric mechanisms underlying neuronal communication and synaptic plasticity. Her academic credentials include: Ph.D. in Molecular Biology and Biochemistry from Harvard University (2010-2015) Bachelor of Engineering in Chemical Engineering from MIT (2006-2010) Bachelor of Science in Molecular Biology and Genetics from MIT (2006-2010) Dr. Hacisuleyman's research program investigates how RNA localization and activity-dependent translational reprogramming regulate neuronal function. Her lab employs proximity-based ribosome profiling and other cutting-edge techniques to dissect dendritic translation mechanisms, with implications for understanding neurological disorders and brain development. This work bridges molecular biology, neuroscience, and RNA biochemistry to uncover fundamental principles of cellular adaptation. Analysis of her 14 publications (2012-2025) reveals three dominant research trajectories: (1) RNA biology in neuroscience (particularly dendritic translation and lncRNA functions), (2) cancer mechanisms involving RNA regulatory networks, and (3) virology applications during the SARS-CoV-2 pandemic. Her most highly cited work focuses on non-coding RNA roles in brain development and viral infection dynamics. Her scientific excellence has been recognized through: Kavli Neuroscience Postdoctoral Fellowship (2021-2023) from the Kavli Neural Systems Institute Helen Hay Whitney Fellowship (2016-2019) supporting her postdoctoral training As Principal Investigator on the active NIH/NIGMS grant 'Decoding RNA Localization and Local Translation: Key Mechanisms of Cellular Adaption and Function' (awarded August 2025), she mentors graduate students Madison Jones (neurological disorders focus) and Ulas Kaplan (5'UTR peptide research), alongside technicians Alexander Valera and Alperen Baran. Her lab maintains strong industry and clinical collaborations for translational applications. The Hacisuleyman Lab operates within UF Scripps' state-of-the-art facilities, combining molecular, cellular, and computational approaches to advance understanding of RNA-mediated cellular regulation in health and disease.

Katharina Makowerمشاهده پروفایل

پژوهشگر ارشد

• Aquatic Ecology
• Plankton Ecology
• Microbial Ecology
• +۳ مورد دیگر

Dr. Katharina Makower serves as a Postdoctoral Researcher in the Department of Plankton and Microbial Ecology (Department 3) at the Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB Berlin), where she contributes to the Zooplankton Ecology research group. Her work integrates molecular biology with ecosystem-level aquatic research through participation in major European infrastructure projects. Her research focuses on plankton dynamics and microbial interactions in freshwater systems, with particular expertise in cyanobacterial physiology and toxin production. Current investigations examine nutrient cycling effects on phytoplankton growth, while earlier work established foundational knowledge about microcystin's role in oxidative stress defense. Dr. Makower employs interdisciplinary approaches combining mesocosm experimentation with genomic analysis to address complex questions in aquatic ecology. Analysis of her publication record reveals a clear trajectory from molecular studies of cyanobacterial toxins toward broader ecosystem investigations. Her recent work emphasizes research infrastructure development, particularly in data management practices for aquatic mesocosm experiments. The publications demonstrate consistent collaboration across European institutions with focus on experimental ecology infrastructure. Dr. Makower actively participates in EU-funded initiatives including AQUANAVI (2024-2026), which develops a navigation platform for aquatic mesocosm facilities, and previously contributed to AQUACOSM-plus (2020-2024) and the original AQUACOSM project (2017-2020). These projects establish critical connections between freshwater and marine experimental research infrastructures across Europe. Within IGB Berlin, she operates in Department 3 (Plankton and Microbial Ecology) with cross-departmental collaboration extending to Department 5 (Evolutionary and Integrative Ecology), reflecting the interdisciplinary nature of modern aquatic research. Her editorial contributions to project deliverables demonstrate growing leadership in coordinating international research efforts.

Michael Jewettمشاهده پروفایل

استاد مدعو

• Synthetic Biology
• Cell-Free Protein Synthesis
• Biomanufacturing
• +۳ مورد دیگر

Michael Jewett is an Adjunct Professor of Chemical and Biological Engineering at Northwestern University's McCormick School of Engineering. His research focuses on synthetic biology, cell-free systems, and glycosylation engineering. He leads the Jewett Lab, which develops novel biomanufacturing platforms and therapeutics. Dr. Jewett holds a Ph.D. from Stanford University and has pioneered methods in cell-free protein synthesis, ribosome engineering, and scalable biocatalyst design. Education: Ph.D. Chemical Engineering, Stanford University (2005) M.S. Chemical Engineering, Stanford University B.S. Chemical Engineering with Bioengineering specialization, UCLA (summa cum laude) Research Interests: Dr. Jewett's work spans synthetic biology applications in healthcare and environmental sustainability. Key areas include: - Cell-free systems for rapid prototyping of biological parts - Engineering ribosomes for novel functions - Glycoengineering for biopharmaceuticals - Development of diagnostic biosensors - Biomanufacturing innovations using modular platforms Grants & Labs: Director of the Jewett Lab at Stanford/NU Recipient of multiple NIH and DOE grants Collaborates with industry partners on scalable bioproduction Labs focus on translating fundamental discoveries into real-world applications like vaccines, diagnostics, and sustainable chemicals.

Matthew H. Sazinskyمشاهده پروفایل

استاد

• Biochemistry
• Structural Biology
• Bio-Inorganic Enzymology
• +۳ مورد دیگر

Matthew H. Sazinsky is a Professor of Chemistry at Pomona College , where he has served since 2007. His research integrates X-ray crystallography and biochemical techniques to investigate protein structure and function, with a focus on metalloenzymes and their roles in bacterial metabolism. Education: Ph.D. from Massachusetts Institute of Technology, B.S. from Haverford College His research spans three primary themes: (1) identifying determinants of metalloenzyme activity , (2) re-engineering proteins for novel functions, and (3) elucidating biochemical processes in pathogenic bacteria . Recent work explores NADH-dependent enzymes , FAD-transfer reactions , and sulfur respiration in Shewanella and Pyrococcus species. Publications reveal trends in metalloprotein structure-function relationships , redox enzyme mechanisms , and biometal interactions in disease contexts like diabetes. Collaborative projects often involve interdisciplinary approaches to enzyme engineering and bacterial physiology. Scientific Awards: Wig Distinguished Professorship Award for Excellence in Teaching (2010) Camille and Henry Dreyfus Faculty Start-Up Award (2007) Dr. Sazinsky has secured competitive grants and mentorship accolades, emphasizing hands-on undergraduate training in structural biology and biochemistry . His lab provides students with opportunities for structural and biochemical characterization of protein targets, fostering early-career research development.

• Mitochondrial Genetics
• Molecular Biology
• Human Disease Genetics
• +۳ مورد دیگر

Dr. Paul Smith is a Research Fellow at Newcastle University specializing in mitochondrial genetics and molecular biology. His work centers on mitochondrial DNA mutations, ribosomal function, and their role in human respiratory chain disorders, particularly reversible infantile conditions. Collaborating with leading researchers including Emeritus Professor Robert Lightowlers and Professor Rita Horvath, he has established a significant research trajectory within Newcastle's mitochondrial disease research group. Smith's primary research focuses on mitochondrial ribosome dysfunction, with emphasis on rRNA and tRNA mutations affecting translation. His work on 16S/12S rRNA mutations, tRNA thiolation defects, and reversible cytochrome c oxidase deficiency has revealed critical pathogenic mechanisms. Key contributions include identifying high-impact mitochondrial mutations, characterizing translation termination defects, and exploring therapeutic approaches for metabolic disorders. His molecular approaches bridge basic biochemistry with clinical applications in mitochondrial medicine. Analysis of Smith's 15 publications (2003-2015) reveals consistent focus on mitochondrial translation mechanisms and respiratory chain pathology. His work demonstrates evolving sophistication from foundational DNA targeting studies (2003) to complex molecular pathogenesis models (2015). Recurring themes include mutation impact prediction, reversible disease mechanisms, and ribosomal dysfunction in human disorders. The publications show strong institutional collaboration patterns, particularly with Newcastle's mitochondrial research cluster, and maintain technical rigor in biochemical and genetic methodologies throughout the publication period.

Neil L. Kelleherمشاهده پروفایل

استاد

• Top-Down Proteomics
• Natural Products Discovery
• Cancer Biology
• +۷ مورد دیگر

Neil L. Kelleher is the Walter and Mary E. Glass Professor of Molecular Biosciences at Weinberg College of Arts and Sciences and Professor of Medicine (Hematology & Oncology) at Feinberg School of Medicine, Northwestern University. He also serves as Director of the Chemistry of Life Processes Institute and Northwestern Proteomics . His research focuses on top-down proteomics , chromatin biology , and natural product discovery . He leads the global Human Proteoform Project (HPfP) to map 250,000 human proteoforms across 4,000 cell types. His lab developed the ProSight software suite , used by over 1,000 labs worldwide. His publications span computational proteomics, cancer epigenetics, and mass spectrometry applications. Recent articles address automated top-down proteomics , histone methylation dynamics , and non-ribosomal peptide synthesis in Molecular Biosystems , Journal of Biological Chemistry , and Chemistry & Biology . Biemann Medal (2009) Pittsburgh Conference Achievement Award (2008) Pfizer Award in Enzyme Chemistry (2006) Presidential Early Career Award for Scientists and Engineers (2005) Kelleher has mentored ~50 Ph.D. students and postdocs. He co-founded startups like Nativetdms.org and IntegratedProteinTechnologies.com . His lab combines Fourier-Transform Mass Spectrometry with intact protein analysis to study proteoforms and their role in disease.