استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشیتان را پیدا کنید و با او ارتباط بگیرید.
نمایش ۱۶-۳۰ از ۶۶۴ استاد راهنما
اطلاعات این پروفایلها از صفحات عمومی دانشگاهها جمعآوری شده و ممکن است بهروز نباشد.
عضو هیئت علمی
Pavel P. Kuksa is a Research Assistant Professor in the Department of Pathology and Laboratory Medicine, specializing in bioinformatics, computer science, and functional genomics. His work focuses on high-throughput sequencing analysis, chromatin interaction data, and developing scalable software platforms for genomics research.
پژوهشگر ارشد
Chris Spencer is a Wellcome Trust Career Development Fellow at the Nuffield Department of Medicine, University of Oxford. His research focuses on statistical genetics, with emphasis on African population genetics, malaria susceptibility (via the MalariaGEN consortium), and stratified medicine applications in hepatitis C (STOP-HCV consortium). He develops methodologies to analyze genetic determinants of host-parasite interactions and their role in disease prevention and treatment. His work explores infectious disease impacts on human immune physiology through natural selection, aiming to translate genetic insights into clinical strategies. Recent studies include structural variation in malaria resistance genes and polymorphisms linked to pneumococcal bacteremia in Kenyan children. His computational tools, such as FINEMAP, advance variable selection in genome-wide association studies. Publications span malaria genetics, viral resistance, and population admixture, reflecting a multidisciplinary approach to genomic medicine. Collaborations with global consortia highlight his commitment to addressing global health challenges through genetics.
Jason Matthews is a Professor in the Department of Nutritional Sciences at the Faculty of Medicine, University of Oslo. He also holds a status-only professorship at the Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Canada. His research focuses on the aryl hydrocarbon receptor (AHR) and its target gene PARP7/TIPARP in the context of cancer, inflammation, and metabolic diseases. Current positions: University of Oslo (since 2015), University of Toronto (status-only since 2016) Education: PhD (2001, Michigan State University), BSc (1997, University of Western Ontario) Matthews' research investigates how AHR and PARP7 enable cancer cells to evade immune detection and promote tumor growth. His work explores therapeutic strategies combining AHR/PARP7 inhibition with immunotherapy to combat cancer progression. Additional studies examine the AHR-PARP7 axis in chronic inflammatory conditions like obesity and atherosclerosis. Recent publications highlight his team's work on AHR inhibition in pancreatic cancer, PARP7's role in interferon signaling, environmental pollutant impacts on immune gene expression, and novel chemical compounds targeting the AHR pathway. These studies employ cell biology, gene editing, genomics, and preclinical cancer models. Collaborations span institutions including University of Toronto, Karolinska Institute, and University of Leeds, focusing on cancer immunology, nutritional sciences, and drug development.
Dr. Steven Jacobsen is a Professor in the Molecular, Cell, and Developmental Biology Department at the University of California, Los Angeles (UCLA), where he leads the Jacobsen Lab. His work focuses on epigenetic inheritance and gene regulation in Arabidopsis thaliana and mammalian stem cells, utilizing genetic screens, genomics, epigenomics, and biochemical approaches. The lab also pioneers CRISPR-mediated genome editing techniques. University: University of California, Los Angeles Department: Molecular, Cell, and Developmental Biology Research Interests: Jacobsen's research spans multiple interconnected domains in epigenetics, including DNA methylation patterning, histone modification interplay, and transposable element silencing. His team investigates how chromatin structure influences gene expression and epigenetic inheritance, with applications from plant development to human health. Key areas include: CRISPR-based epigenetic modifications RNA-directed DNA methylation (RdDM) mechanisms Chromatin compaction via MORC proteins Histone variant functions in methylation Transposon control in plant genomes Comparative epigenomics across species Advising Legacy: Over two decades, Dr. Jacobsen has mentored 21 former lab members who now hold academic and industry positions globally, including professors at Chinese Academy of Sciences, University of Georgia, and Southern University of Science & Technology. His lab's publications reveal a consistent focus on DNA methylation dynamics, chromatin remodeling, and small RNA pathways, with recent work emphasizing CRISPR innovations and structural insights into epigenetic regulators.
Guillaume Bourque is a Professor in the Department of Human Genetics at McGill University's Faculty of Medicine. He serves as an Investigator at the Victor Phillip Dahdaleh Institute of Genomic Medicine and as the Scientific Director of the Canadian Centre for Computational Genomics (C3G). His laboratory is based at 740 Dr Penfield Ave, Room 6103, Montréal, Québec, Canada, H3A 1A4, where he leads research in computational genomics and bioinformatics. Professor Bourque's research focuses on understanding mammalian genomes using comparative genomic and epigenomic analyses. His lab investigates the evolution of regulatory sequences , the role of transposable elements in gene regulation , and the impact of genome rearrangements in evolution and cancer . His team develops computational methods and resources for the functional annotation of genomes with special emphasis on sequencing-based assays including ChIP-seq, RNA-Seq, exome- and whole-genome sequencing, and single-cell analysis. The lab's work involves examining billions of DNA base pairs to interpret how variation impacts basic biology and disease. Recent publications (2024-2025) demonstrate Bourque's leadership in pangenome graph construction , transposable element analysis , epigenomic profiling , and cancer genomics . His work spans multiple disciplines from basic genome evolution to clinical applications in cancer and infectious disease. Notable projects include the development of tools like DeepPolisher for genome assembly polishing and contributions to understanding the genomic basis of long COVID. Bourque's laboratory is actively recruiting postdocs and graduate students with backgrounds in programming or statistics. The lab emphasizes quantitative approaches to biology, requiring applicants to have experience in quantitative biology as a plus. His collaborative work extends across multiple institutions and international consortia, reflecting the interdisciplinary nature of modern genomic research.
دانشیار
Zhipeng Lu is currently an Associate Professor of Pharmacology and Pharmaceutical Sciences at the University of Southern California (USC) School of Pharmacy. His research focuses on understanding RNA molecules and their structural complexity as a second layer of genetic instructions beyond protein encoding. He directs the Lu Lab at USC, which develops and applies novel technologies to investigate RNA structures, interactions, chemical modifications, and functions in cellular processes and animal development. Dr. Lu's research interests center on "RNA machines" in living cells, with particular emphasis on how RNA molecules fold into structures and form intermolecular interactions to execute genetic instructions. His work spans multiple dimensions of RNA biology, including RNA structure-function relationships, RNA-protein interactions, RNA modifications, and the role of RNA in human diseases such as genetic disorders and viral infections. The lab combines computational, chemical, and biological approaches to elucidate fundamental mechanisms of RNA machines, with the ultimate goal of developing new understanding and therapies targeting human diseases. Analysis of Dr. Lu's publication history reveals a strong trajectory in RNA structure and interaction mapping technologies. His work has evolved from foundational studies on RNA processing and modification to developing innovative high-throughput methods like PARIS and RISE for analyzing RNA interactomes. Recent publications focus on specific RNA systems like XIST and snoRNAs, demonstrating how his lab has moved from method development to applying these tools to solve longstanding biological questions in epigenetics and RNA therapeutics. Dr. Lu has received numerous prestigious awards recognizing his contributions to RNA research: NHGRI K99/R00 NIH Pathway to Independence Award (2017-2022) RNA Society Scaringe Award (2017) Stanford University Jump Start Award for Excellence in Research (2016-2017) Damon Runyon-Sohn Fellowship (2015-2017) His research is supported by multiple funding sources from organizations including the National Institutes of Health and other foundations. The Lu Lab is actively recruiting PhD students and postdoctoral researchers to work on several cutting-edge directions including RNA structures, interaction networks, RNA modification mechanisms, and their roles in development and disease. The lab integrates biological, chemical, and computational approaches to advance RNA biology and push forward RNA medicine. The Lu Lab at USC is a dynamic research environment focused on "RNA machines" with recent highlights including solving aspects of the orphan snoRNA problem and discovering snoRNAs that control eMet tRNA activity. The lab's vision emphasizes creative exploration of RNA biology, with researchers encouraged to pursue innovative ideas much like "wild animals running in the African savannah." Current research directions include analysis of RNA structures, interaction networks, RNA modification mechanisms, and their roles in development and disease, with applications to genetic disorders, cancers, and viral infections.
Rachel O'Neill serves as a Board of Trustees Distinguished Professor in the Department of Molecular and Cell Biology at the University of Connecticut's College of Liberal Arts and Sciences. Her research bridges molecular genetics, cytogenetics, and computational genomics to investigate fundamental mechanisms of genome stability and evolution across diverse eukaryotic species. Her primary research interests focus on retroelement transcription, centromere function, chromosome evolution, and species-specific genomic adaptations. O'Neill's lab pioneers telomere-to-telomere (T2T) genome assembly methodologies using next-generation sequencing technologies, establishing non-traditional model organisms including marsupials, monotremes, birds, marine species, plants, and insects for comparative genome biology studies. Human Telomere-to-Telomere Consortium Primate T2T Consortium Gibbon T2T Consortium Earth Biogenomes Project Ruminant T2T Consortium Fly T2T Consortium Deep Ocean Genomes Project Antarctic Genomes Consortium Colossal Foundation UConn’s Biodiversity and Conservation Genomics program O'Neill's recent publications (2021-2025) demonstrate leadership in large-scale genomics initiatives, with significant contributions to understanding centromere biology, sex chromosome evolution, and conservation genomics. Her work spans marsupial mole genomics, ruminant chromosome evolution, and epigenetic regulation of X-chromosome inactivation, reflecting her lab's broad impact across evolutionary biology, conservation, and fundamental genome science. Her laboratory actively trains students through cohort-based programs including the RaMP Cohort and Biodiversity and Conservation Genomics Program, securing substantial collaborative funding through multi-institutional consortia. The lab maintains strong infrastructure for advanced genome assembly and epigenomic analysis, with particular expertise in challenging repetitive regions and non-model organism genomics.
Prof. Heike Krebber is a Professor for Molecular Genetics at Georg-August University Göttingen, Germany. Her research focuses on mRNA quality control and non-coding RNA functions, using the model organism Saccharomyces cerevisiae. She has held positions at the DKFZ (Heidelberg), Harvard Medical School, and Philipps-Universität Marburg. Her work addresses how mRNA processing defects contribute to diseases like cancer and neurodegeneration. Education & Positions: PhD (1996), Deutsches Krebsforschungszentrum Heisenberg Fellow (2006) Habilitation in Molecular Biology (2005) Professor since 2010 at Georg-August University Research Interests: Her lab investigates: RNA quality control mechanisms ensuring proper mRNA maturation and export Functions of non-coding RNAs (e.g., lncRNAs in iron metabolism and telomerase) Ribosome assembly and translation termination pathways Stress-induced bypass of mRNA quality control Awards: Heisenberg Fellowship (2006) Grants & Teams: Leads the Molecular Genetics group at the Institute for Microbiology and Genetics. Collaborates with the IMPRS Molecular Biology and GZMB (Molecular Biology of Cells) programs. Labs & Affiliations: Her group is part of the GGNB network, focusing on Microbiology and Biochemistry. The lab’s work spans fundamental molecular mechanisms with translational disease relevance.
Barış Ethem Süzek is an Associate Professor in the Department of Computer Engineering at the Faculty of Engineering, Muğla Sitki Koçman University. His academic career spans institutions including Middle East Technical University (BS), Johns Hopkins University (MS), and George Mason University (PhD) in Computational Biology. He specializes in bioinformatics and computational biology, focusing on protein informatics, genetic analysis, and machine learning applications in medical research. Education BS: Middle East Technical University - Computer Engineering (1997) MS: Johns Hopkins University - Computer Science (2000) PhD: George Mason University - Computational Biology (2012) His research integrates bioinformatics with molecular dynamics, particularly in host-pathogen interactions, regenerative medicine, and genomic data analysis. He has developed machine learning tools for viral interaction prediction and variant analysis systems. His work with UniProt and cancer Biomedical Informatics Grid projects demonstrates expertise in large-scale biological data integration. Scientific awards include Collaboration, Outstanding Achievement, and Change Agent Awards from the cancer Biomedical Informatics Grid, plus multiple patent recognitions for biomedical systems. He has supervised numerous graduate students in bioinformatics, computational genetics, and forensic biology projects.
Andreas Matouschek is a Professor in the Department of Molecular Biosciences at the University of Texas at Austin, where he served as Associate Dean for Research and Facilities from 2020-2024. He oversees research support for the College of Natural Sciences, managing over 1 million square feet of research space across multiple campuses. Prior to joining UT Austin in 2012, he spent 15 years at Northwestern University where he held leadership roles including Program Leader for Cancer Cell Biology in the Robert H. Lurie Comprehensive Cancer Center. Matouschek received his education at prestigious institutions: Diplom in Biology from Ludwig-Maximilians-University in Munich (1990), Ph.D. in Chemistry from Cambridge University (1992), and was an EMBO Fellow at the Biocenter of the University of Basel. His research focuses on the mechanisms of protein machines, particularly protein folding, unfolding, and degradation. The Matouschek Lab investigates the biochemical mechanisms of the Ubiquitin Proteasome System (UPS) in physiologically relevant contexts, with the goal of understanding how cellular processes are regulated through protein degradation. The lab employs diverse experimental techniques including protein engineering, quantitative biochemical assays, cell biology, genome-scale screens, and single molecule biophysics. Analysis of his recent publications reveals a consistent focus on proteasome structure and function, substrate recognition mechanisms, and the regulation of protein degradation. His work has significant implications for understanding cellular regulation and developing therapeutic approaches targeting the ubiquitin-proteasome system. As Associate Dean, he managed a team of 17 full-time staff supporting research across the College of Natural Sciences, including facilities spanning from the McDonald Observatory in West Texas to the Marine Science Institute on the Gulf Coast. His laboratory continues to make significant contributions to understanding the fundamental mechanisms of protein degradation and its implications for cellular function and disease.
Professor Adele Murrell is a Professor of Epigenetics in the Department of Life Sciences at the University of Bath's Faculty of Science. She serves as Co-Director of the Centre for Therapeutic Innovation and is affiliated with both the Centre for Mathematical Biology and the Centre for Bioengineering & Biomedical Technologies (CBio). She is currently accepting doctoral students and maintains an active research program with multiple ongoing projects. Her research focuses on understanding how cells establish and maintain their specific identities through epigenetic mechanisms. Her work centers on epigenetic barriers and cell identity, genomic imprinting as a model epigenetic system, long-range epigenetic silencing in cancer, and epigenetic reprogramming during metastasis. She investigates how higher-order chromatin structure and epigenetic modifications shape the genome within the nucleus to constitute cell identity and provide memory of developmental origins. Her current work examines colon cancer and liver metastasis, focusing on changes in DNA methylation and its demethylation intermediates such as 5-hydroxymethylcytosine. Analysis of Professor Murrell's recent publications reveals a strong focus on DNA hydroxymethylation patterns in cancer progression, particularly in colorectal cancer metastasis. Her work bridges molecular epigenetics with clinical applications, exploring how epigenetic changes during metastasis could be targeted to prevent cancer spread. She has developed novel techniques for detecting epigenetic modifications and has made significant contributions to understanding allele-specific chromatin domains and genomic imprinting mechanisms. Professor Murrell leads multiple research projects including 'Two stages of genome wide 5-hydroxymethylcytosine (5hmC) reprogramming during colorectal carcinogenesis and liver metastasis' funded by the MRC until February 2024, and 'Modelling the fits and starts of how genes burst into expression' funded by The Leverhulme Trust until June 2024. She was also a Co-Investigator on the 'Multi User High-Content Confocal Microscope' project funded by the Biotechnology and Biological Sciences Research Council. Her laboratory work connects with UN Sustainable Development Goals, particularly those related to health and well-being. Her fingerprint analysis shows strong activity in Epigenetics (100%), DNA Methylation (94%), Allele research (73%), Methylation studies (69%), Genomic Imprinting (60%), CTCF research (56%), Promoter Region analysis (44%), and Differentially Methylated Regions (34%).
مدرس ارشد
Dr. Irene Nobeli is a Senior Lecturer and Education Lead (PG taught courses) at the School of Natural Sciences, Birkbeck, University of London. She specializes in computational biology and chemoinformatics, focusing on regulatory RNAs, transcriptomics in health/disease, brain disorders, and small molecule roles in biology. Her work bridges bioinformatics tools development and translational research. Administrative roles include directing the MSc Bioinformatics program and organizing the Sequence Analysis and Omics module. She collaborates with research centers like the Birkbeck Institute for Data Analytics (BIDA) and the Institute of Structural Molecular Biology (ISMB). Research interests span bioinformatics methodologies, Mycobacterium genomics, neurodevelopmental disorders, and computational drug design. Notable contributions include developing flexiMAP (alternative polyadenylation analysis) and baerhunter (bacterial non-coding RNA detection). Publications highlight her expertise in transcriptomics, bacterial pathogenesis, and neurobiological mechanisms. She actively engages in advancing computational methods for genomic data interpretation and translational medicine.
مدرس ارشد
Dr. Satrya Fajri Pratama is a Senior Lecturer in Computer Science at the University of Hertfordshire , affiliated with the School of Physics, Engineering & Computer Science and the Department of Computer Science . With professional certifications from Oracle, Microsoft, Google, AWS, Cisco, and other industry leaders, he combines academic expertise with practical industry recognition. His research focuses on software development, internet of things (IoT), cloud computing, and computational approaches to drug classification. Doctor of Philosophy (ICT) – Universiti Teknikal Malaysia Melaka Master of Science in ICT – Universiti Teknikal Malaysia Melaka Bachelor of Computer Science (Software Development) – Universiti Teknikal Malaysia Melaka His research involves descriptor selection for drug classification using advanced algorithms like the Whale Optimization Algorithm and Particle Swarm Optimization , particularly in combating Amphetamine-Type Stimulants (ATS) . Collaborative work includes ncRNA identification and QSAR modeling for biodegradation studies. Key scientific awards include certification as a Professional Technologist with the Malaysia Board of Technologists (MBOT) and recognition as an Apple Teacher with Swift Playgrounds Recognition . He holds numerous industry certifications and is a certified educator/trainer for Microsoft, Google, AWS, Oracle, and other major tech companies.
CHEN Wei is a Chair Professor at the Department of Biology, School of Life Sciences, Southern University of Science and Technology (SUSTech), Shenzhen, China. He holds a Ph.D. from the Max Planck Institute for Molecular Genetics (2006) and previously served as a Full Professor (W3) at the Max-Delbrück Center for Molecular Medicine and Charité – Universitätsmedizin Berlin (2015-2016). Prior to joining SUSTech, he led research groups at prestigious German institutions, contributing to large-scale genome centers and the Berlin Institute of Health. Education : Ph.D. (2006, Max Planck Institute), M.S. (2002, Sichuan University), B.S. (1993, Xiamen University) His research focuses on systems biology and genomics, particularly post-transcriptional gene regulation mechanisms and their roles in human diseases. His lab integrates next-generation sequencing technologies with computational approaches to study non-coding RNA functions, alternative splicing, and chromatin dynamics. Key projects include CRISPR-based functional studies, 3D genome analysis, and RNA editing in neurological and metabolic disorders. Recent publications highlight his work in Drosophila developmental genomics, chloroplast translation control, and cancer biology. The 2025 study on spatiotemporal multi-omics in Drosophila and 2024 articles on MatK's role in tRNA splicing and CRISPR-activated transcriptional regulation exemplify his interdisciplinary approach. Earlier works (2023-2022) address immune cell trafficking, alternative polyadenylation, and chromatin remodeling in cancer metastasis. At SUSTech, he leads a team with 4 research assistant professors, 2 postdoctoral fellows, 3 research assistants, and 7 graduate students. His lab has secured significant funding from EU and German agencies (€7M+), though specific awards are not detailed in the provided text. Teaching responsibilities include General Biology and Principles of Cell Biology.
Jef D. Boeke is the Sol and Judith Bergstein Director of the Institute of Systems Genetics and a Professor in the Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine. He holds a PhD from Rockefeller University and has pioneered research in synthetic biology, retrotransposition mechanisms, and yeast genetics. His work includes leading the international Sc2.0 project to synthesize the first eukaryotic genome and the 'Dark Matter Project' exploring non-coding DNA functions. Research interests focus on genome engineering, synthetic genomics, epigenetics, and applications to cancer biology. His lab develops CRISPR tools and synthetic regulatory systems, with notable contributions to understanding LINE-1 retrotransposons and chromatin structure. Over 489 publications highlight his work in Nature Communications, Molecular Cell, and Science. Awards: While specific prizes aren't listed, his leadership in groundbreaking projects like Sc2.0 and contributions to synthetic biology underscore his influential career. Grants and funding details are implied through active research programs. Advising: Supervises a multidisciplinary team of postdocs and graduate students working on projects ranging from antibiotic engineering to de-extinction approaches. Lab collaborations include international partnerships and industry-driven biotech applications. Labs/Teams: Directs the Boeke Lab, a hub for synthetic genome engineering and systems genetics. The lab’s interdisciplinary team bridges molecular biology, computational biology, and engineering to solve complex biological problems.
