جستجوی استاد راهنمای دانشگاهی

Xiaoyong Bao is an Associate Professor of Pediatrics in the Division of Clinic and Experimental Immunology and Infectious Disease at the University of Texas Medical Branch (UTMB) School of Medicine. Her research bridges virology, immunology, and molecular biology with a focus on viral pathogenesis and host responses. Dr. Bao received her PhD in Cellular Physiology and Molecular Biophysics from UTMB and completed postdoctoral training as a J.Kempner scholar (2003-2004) followed by a NIAID-supported T32 fellowship in emerging infectious diseases at UTMB. Her primary research interests include: Biological roles of small non-coding RNAs (sncRNAs), particularly tRNA-derived fragments, in viral infection responses Mechanisms of immune evasion by respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) Developing therapeutic molecules and attenuated vaccine candidates against respiratory viruses Investigating connections between viral infections and neurodegenerative diseases like Alzheimer's Analysis of her recent publications reveals a strong trend toward interdisciplinary research connecting virology with RNA biology and neurodegenerative disease mechanisms. Her work has increasingly focused on tRNA-derived RNA fragments across multiple disease contexts including respiratory viral infections and Alzheimer's disease, demonstrating a sophisticated approach to understanding fundamental molecular mechanisms that span traditional disciplinary boundaries. Dr. Bao serves as Principal Investigator on multiple active research projects including: EPAC1 as a Crucial Host Factor and Therapeutic Target of SARS-CoV-2 (American Lung Association, 2024-2026) tRNA-derived RNA Fragments research related to Alzheimer's Disease (National Institute on Aging, 2023-2026) tRNA-derived RNA Fragments in Nasal SARS-CoV-2 Infection (NIAID, 2022-2026) These projects demonstrate substantial funding support from major national institutions including the National Institutes of Health and the American Lung Association. Her laboratory work focuses on molecular mechanisms underlying pathogenesis and host immune responses to RSV and hMPV infections, aiming to identify antiviral pathways, viral evasion mechanisms, and roles of sncRNAs. The ultimate goal of her research is to develop effective preventive and therapeutic strategies against respiratory virus-associated viral replication and inflammation.

• Virology
• Immunology
• Molecular Biology
• +۷ مورد دیگر

Dr. Ilgin Cagnan Cakkol serves as an Associate Professor in the Department of Biological Sciences at Eastern Mediterranean University's Faculty of Arts and Sciences. She maintains her office in AS112 and can be reached at +90 392 630 2675 or via email at ilgin.cagnan@emu.edu.tr. Her educational background includes a PhD in Stem Cell research from Hacettepe University (2018), an MS in Life Sciences from the University of Edinburgh (2009), and a BS in Biological Sciences from the University of Edinburgh (2008). Dr. Cakkol's research spans multiple critical areas in molecular biology and medicine, with particular emphasis on stem cell biology, Fanconi anemia, cancer mechanisms, and genetic regulation. Her work demonstrates significant contributions to understanding mesenchymal stem cell behavior in Fanconi anemia patients , breast cancer molecular pathways , and miRNA expression patterns in various disease contexts. Through her research, she has established important connections between genetic factors and disease progression, particularly in hematological disorders and oncology. Analysis of her publication record from 2011-2023 reveals a strong research trajectory focused on molecular mechanisms in stem cells and cancer. Her work shows increasing specialization in Fanconi anemia and mesenchymal stem cell biology after 2015, with several publications examining HOX/TALE gene networks and their implications for bone marrow failure. The most recent publications (2021-2023) demonstrate expansion into women's health research and host genetics related to infectious diseases. Publication Award by EMU (2023) Publication Award by EMU (2022) Publication Award by EMU (2021) (three instances) Meliha Terzioğlu Science Award (2018) 2nd Prize for Poster Presentation (2014) Short Term Scientific Missions (2013) COST Training School (2011) Dr. Cakkol has secured multiple research grants from prestigious funding bodies including TUBITAK and European Union programs. Her current projects include the Cyprus Dysmenorrhea (CypDy) Project and Period Poverty initiative, alongside continued research on HOX/TALE transcription factors in Fanconi Anemia. She has demonstrated success in building international collaborations through projects examining stem cell therapies for lung cancer and breast cancer diagnostics. Her research group likely focuses on molecular characterization of stem cells in disease contexts, with particular attention to genetic and epigenetic regulatory mechanisms.

• Stem Cell Research
• Molecular Biology
• Cancer Research
• +۵ مورد دیگر

Andrea J. Berman is an Associate Professor in the Department of Biological Sciences at the University of Pittsburgh's Dietrich School of Arts and Sciences, where she has led an active research program since joining the faculty in 2012. Her work centers on RNA biology, specifically investigating how non-coding RNA and ribonucleoprotein complexes regulate gene expression through conformational changes in translation mechanisms. Education: Ph.D. in Molecular Biophysics and Biochemistry, Yale University (2007) under Nobel laureate Thomas Steitz Postdoctoral Research, University of Colorado, Boulder with Nobel laureate Thomas Cech Dr. Berman's laboratory employs an integrated approach combining biochemical assays, structural analysis, and computational modeling to dissect RNA-mediated translation control. Her research has revealed critical roles for proteins like LARP1 in ribosome biogenesis and TOP mRNA regulation, with significant implications for understanding genetic disorders. Recent work has expanded into reproductive genetics, where her team identifies and characterizes pathogenic variants underlying infertility conditions. Analysis of her 2021-2025 publications shows a cohesive research trajectory focused on reproductive medicine, with 70% of recent work dedicated to male infertility (azoospermia) and ovarian insufficiency. Key contributions include genomic identification of DMC1, Tcte1, and ZSWIM7 variants, establishing novel genetic pathways in human reproduction. Contact Information: Email: ajb190@pitt.edu Office: A323 Langley Hall, 4249 Fifth Avenue, Pittsburgh, PA 15260 Phone: (412) 624-2200

• RNA Biology
• Gene Expression Regulation
• Non-coding RNA
• +۴ مورد دیگر

Andrew Modzelewski, Ph.D., is an Assistant Professor of Molecular Biology at the University of Pennsylvania School of Veterinary Medicine. His research focuses on retrotransposon reactivation in mammalian development and disease, particularly during preimplantation embryogenesis and in pathological states like cancer. University: University of Pennsylvania School: School of Veterinary Medicine Department: Department of Molecular Biology Contact: amodz@upenn.edu The Modz Lab develops technologies such as CRISPR-EZ for efficient mouse genome engineering and Tri-Blot for single-cell triple measurements. His work bridges transposon biology with epigenetic regulation, exploring their roles in aging, disease, and developmental innovation. Recent publications highlight his contributions to understanding retrotransposon-driven developmental mechanisms, CRISPR-EZ optimization, and transposon domestication in genomic evolution. The lab emphasizes both fundamental research and practical tool development for the broader scientific community. Located at 380 S. University Ave, Philadelphia, the Modz Lab operates 24/7 and collaborates across disciplines to address challenges in human health and reproduction.

• Retrotransposon Reactivation
• Transposon Domestication
• CRISPR Technology
• +۶ مورد دیگر

Tigran A. Harutyunyan is an Associate Professor at Yerevan State University in the Faculty of Biology, Department of Genetics and Cytology. Since 2025, he has served as Head of the Genomic Instability and Molecular Mutagenesis Group at the university's Institute of Biological Sciences. He holds a Candidate of Sciences degree (2015) and an Associate Professor title (2021) in Biological Sciences, having completed his postgraduate (2012-2015), Master's (2010-2012), and Bachelor's (2006-2010) education at the same institution under scientific advisor Ruben M. Harutyunyan. His research focuses on: Molecular mechanisms of mutagenesis and DNA damage Mitochondrial genome dynamics and intercellular transfer Genomic instability in cancer, aging, and viral infections Development of molecular cytogenetic approaches for genotoxicity assessment He maintains active international collaborations, particularly with Friedrich Schiller University in Germany. Harutyunyan's recent publications (2022-2025) demonstrate strong emphasis on: Mitochondrial DNA alterations in disease contexts DNA damage responses to chemotherapy, radiation, and viral infections Cancer biology mechanisms and therapeutic targeting Application of genome editing (CRISPR/Cas9) in disease models He leads the Genomic Instability and Molecular Mutagenesis Group, where his team investigates molecular carcinogenesis, genotoxic stress responses, and develops novel diagnostic approaches using cell-free DNA biomarkers.

• Molecular Mutagenesis
• Genome Editing
• Mitochondrial DNA
• +۵ مورد دیگر

Laura Landweber is a Professor at Columbia University, affiliated with the Departments of Biochemistry and Molecular Biophysics, Biological Sciences, and Systems Biology in the Colleges of Physicians & Surgeons and Arts & Sciences. She previously served as faculty at Princeton University (1994-2016) and was a Junior Fellow at Harvard University (1993). Her research focuses on microbial eukaryotes with complex genome architectures, particularly the ciliate Oxytricha, investigating RNA-mediated epigenetic inheritance, genome rearrangement, and the co-evolution of transposons with genomic systems. Her work has been recognized through prestigious awards such as the Guggenheim Fellowship (2012), Blavatnik Award (2008), and fellowship in the American Association for the Advancement of Science (AAAS, 2005). She served as President of the Society for Molecular Biology and Evolution (2017) and contributed to advisory panels for the NSF, NIH, and NASA. Recent publications emphasize genome evolution, RNA-guided DNA reorganization, and computational tools for analyzing complex genomes. Her lab employs functional and comparative genomic experiments to study RNA’s role in programming genome architecture across generations, leveraging Oxytricha’s dual-nucleus system to dissect mechanisms of DNA rearrangement and epigenetic memory. Guggenheim Fellowship (2012) Blavatnik Award for Young Scientists (2008) AAAS Fellow (2005) President, Society for Molecular Biology and Evolution (2017) Her educational background includes an AB in Molecular Biology from Princeton University (1989) and a PhD from Harvard University (1993). She has edited three books and authored over 150 publications spanning genetics, evolution, and biological computation.

• Genome Evolution
• Genome Rearrangement
• Molecular Evolution
• +۳ مورد دیگر

Fahd Al-Mulla is a Professor of Molecular Pathology and Genomic Medicine at Kuwait University, with a dual role as Chief Scientific Officer at Dasman Diabetes Institute. He established two research laboratories at Kuwait University, including a large core facility serving over 600 academics and students. His work bridges molecular pathology and genomic medicine to address metabolic diseases. Research Interests focus on: Metabolic paradigms in cancer and diabetes Inflammatory signaling pathways (e.g., NF-κB, TNFα) Adipose tissue dysfunction in obesity Molecular mechanisms of diabesity SARS-CoV-2 spike protein interactions Caveolin-1 polymorphisms and metabolic diseases Publications highlight his expertise in inflammation, obesity, and molecular disease models. He collaborates extensively, with recent work on ANGPTL8 variants and cardio-metabolic disease relationships. Editorial Contributions include a review editor role for Clinical Diabetes and Frontiers in Endocrinology .

• Molecular Pathology
• Genomic Medicine
• Cancer Metabolism
• +۵ مورد دیگر

Jeffrey Mason is an Associate Professor at the College of Veterinary Medicine, Utah State University . His research focuses on reproductive aging , the ovarian microenvironment , and orthopedic disease in post-reproductive female mammals. Education: PhD in Physiology (Reproductive Biology, UC Davis, 2007) MS in Transgenics (UC Davis, 2001) BS in Animal Science (UC Davis, 1999) MBA in Business Administration (Utah State University, 2025) His research interests include: Reproductive Physiology Molecular mechanisms of ovarian aging Orthopedic disease in aging females Gene therapy for laminitis and osteoarthritis Epigenetic changes during menopause Publications span molecular biology, aging, and veterinary science, with recent work on: Exosome transcriptome modulation in aging Senolytic drug efficacy in menopausal models Calorie restriction and redox status Wnt/Dkk gene therapy for bone architecture Scientific awards include NIH study section reviewer (2020-2021) Ellison Medical Foundation Fellowship (2011) APS Porter Physiology Development Award (2007) Multiple teaching and research fellowships (1999-2021) Teaching includes Veterinary Physiology I & II (2014-2025) and Endocrinology (2019). He has mentored graduate students in Animal, Dairy & Vet Sciences since 2002.

• Reproductive Physiology
• Aging
• Orthopedic Disease
• +۲ مورد دیگر

Dr. Marcel Friedrichs is a Researcher at the Faculty of Engineering , Bielefeld University , Germany. He is affiliated with both the Algorithmic Cheminformatics Group and the Center for Biotechnology (CeBiTec) , contributing to interdisciplinary research at the intersection of computational methods and biomedical systems. Researcher in Algorithmic Cheminformatics Group Center for Biotechnology (CeBiTec) member Focus on graph-based data integration and biomedical networks Research Interests : Computational biology, systems biology, bioinformatics tool development, and medical biochemistry. His work emphasizes automated data integration, modeling of regulatory networks, and analysis of gene-disease comorbidities. Article Trends : Publications span 2018–2025, highlighting graph-based data integration, stem cell differentiation (cardiomyocytes), miRNA databases, clinical trial analysis, and pharmacological network modeling. Key keywords include Computational Biology , Medical Biochemistry , and Graph Theory . Labs & Teams : Algorithmic Cheminformatics Group (Faculty of Engineering) Center for Biotechnology (CeBiTec) Contributor to projects like BioDWH2 and GenCoNet

• Computational Biology
• Systems Biology
• Medical Biochemistry
• +۳ مورد دیگر

Dr. Raheleh Rahbari is a Cancer Research UK Career Development Fellow and Group Leader at the Wellcome Sanger Institute, where she leads the Rahbari Group within the Cancer, Ageing and Somatic Mutation Programme. Her research focuses on understanding mutations acquired during ageing and how they can predispose to disease across generations. Dr. Rahbari's research interests span several key areas: Studying variation in germline mutation rates across families Investigating mutational processes operative in the germline Examining the impact of germline genetic mosaicism in offspring Using somatic mutations to infer the clonal dynamics of germline tissues Understanding how mutations acquired during ageing contribute to cancer predisposition Her recent publications demonstrate a strong focus on mutational landscapes in both somatic and germline cells, with particular emphasis on how these mutations relate to cancer development and predisposition. Her work often employs cutting-edge genomic and computational approaches to analyze mutation patterns across different tissues and disease states, revealing insights into clonal dynamics, mutation rates, and the impact of environmental and genetic factors. Dr. Rahbari has been recognized with a Cancer Research UK Career Development Fellowship, supporting her independent research program. She currently supervises several PhD students including Isaac Garcia-Salinas and Maria Torra I Benach, and has previously supervised Sean Laidlaw, Thomas RW Oliver, and Andrew J C Russell. Her research is supported by Cancer Research UK and involves collaborations with multiple research groups at the Sanger Institute. Dr. Rahbari leads the Rahbari Group, which focuses on cancer predisposition and ageing, using both wet lab and computational approaches to study mutational processes in normal and precancerous tissues.

• Cancer genetics
• Ageing
• Germline mutations
• +۵ مورد دیگر

Carolyn Sangokoya, MD, PhD, is a physician-scientist and board-certified pathologist at the University of California, San Francisco (UCSF) School of Medicine. She serves as an Assistant Professor in the Department of Pathology, focusing on post-transcriptional regulation, stem cell biology, and liver pathobiology. Stanford University (AB in Human Biology, Molecular Genetics concentration) Duke University (MD/PhD in Medical Scientist Training Program) UCSF (Anatomic & Gastrointestinal Pathology fellowships, postdoctoral training) Her research integrates genome engineering and single-cell cytometry to decode molecular networks in cell fate reprogramming. She investigates iron homeostasis, endocytosis, and signaling pathways in regenerative medicine, particularly for metabolic dysfunction-associated steatohepatitis (MASH). Recent work includes biosensor development for iron regulation and endocytic pathway analysis in stem cell transitions. Key publication themes include: Iron regulatory protein dynamics (2025) Single-cell endocytosis quantification (2022) MicroRNA control of pluripotency via PFN2 inhibition (2020) Stress-response microRNAs in liver and hematological diseases (2013-2010) Major awards span career development grants (NIH K08, Burroughs Wellcome), leadership recognitions (ISSCR Public Service Award), and innovative research honors (Gordon Research Conferences Travel & Session Chair). She leads NIH-funded projects on embryonic stem cell fate regulation and contributes to precision diagnostics for chronic liver disease.

• Molecular Biology
• Genetics
• Stem Cell Research
• +۵ مورد دیگر

Jonathan Chou is a physician-scientist at the University of California, San Francisco (UCSF) School of Medicine, actively contributing to both clinical practice and translational research in genitourinary oncology. As an attending physician in the Genitourinary Medical Oncology Clinic and member of the Division of Hematology/Oncology, he bridges patient care with innovative investigations into cancer biology. MD and PhD in Biomedical Sciences, UCSF A.P. Giannini Postdoctoral Fellow, 2018 Research focus on prostate and bladder cancer mechanisms Chou's research explores cancer biology with emphasis on transcription-replication conflicts and CDK12 regulation . His lab develops novel CAR T and radioimmunotherapies for genitourinary malignancies, utilizing transcriptomic and proteomic approaches to identify therapeutic targets. Current projects investigate resistance mechanisms to antibody-drug conjugates , synthetic lethality , and immunotherapeutic targets in aggressive cancer subtypes. His article analysis reveals expertise in prostate cancer (CDK12 biology, radioimmunotherapy), bladder cancer (TM4SF1, CA125+ cell states), and cross-cutting themes in genomic instability , translational imaging , and precision medicine . Research trends show integration of functional genomics (CRISPR screens), clinical trials (IMPACT trial), and health equity initiatives. Scientific recognition includes: Young Investigator Awards (BCAN 2023, Prostate Cancer Foundation 2020) DoD Physician Research Award (2019) Multiple UCSF fellowships (2017-2018) Goldwater Scholar (2003) Chou's clinical training under Eric Small, Terence Friedlander, and Chuck Ryan, combined with postdoctoral work with Felix Feng and Alan Ashworth, positions him at the intersection of clinical oncology and cutting-edge cancer research . His educational background from Stanford University and mentorship under Zena Werb further strengthens his foundation in tumor microenvironment and metastasis regulation studies.

• Translational Oncology
• Prostate Cancer Biology
• Bladder Cancer Research
• +۶ مورد دیگر

Dr. Alexandra Dumitrescu is an Associate Professor in the Department of Medicine-Endocrinology at the University of Chicago. Her NIH-funded research program focuses on genetic disorders of thyroid hormone metabolism, including defects in hormone transport (MCT8), receptor function, and selenoprotein synthesis (SECISBP2). She leads multiple research grants including R01DK110322 investigating SBP2 deficiency syndromes and serves as Co-PI on R01DK015070 studying inherited thyroid disorders. Research Focus Dr. Dumitrescu's research examines: Thyroid hormone transport mechanisms across biological barriers Genetic basis of congenital hypothyroidism and thyroid hormone resistance Selenoprotein biology in thyroid function Therapeutic strategies for transport defects including gene therapy approaches Fetal thyroid physiology and placental transport mechanisms Publication Trends Her recent work demonstrates strong focus on: Novel therapies for MCT8 deficiency including combined drug treatments and AAV gene delivery Genetic characterization of thyroid disorders across diverse populations Role of non-coding mutations in thyroid regulation Advanced models including cerebral organoids for disease mechanism studies Prenatal interventions for inherited transport defects Research Funding R01DK110322 (PI): Mouse Sbp2 deficiency models (2016-2021) F32DK091016 (PI): Pathophysiology of SBP2 abnormalities (2011-2012) R01DK015070 (Co-I): Thyroid Physiology Studies (1979-2027)

• Thyroid Hormone Metabolism
• Genetic Disorders
• Selenoprotein Biology
• +۳ مورد دیگر

Laurent Thomas is a Researcher at the Department of Clinical and Molecular Medicine within the Faculty of Medicine and Health Sciences at the Norwegian University of Science and Technology (NTNU). He maintains dual affiliations with the Unit for Molecular Biology's Bioinformatics and Gene Regulation group and the K.G. Jebsen Center for Genetic Epidemiology. Education: Ph.D. in Bioinformatics, Norwegian University of Science and Technology (NTNU) Postdoctoral training at NTNU Dr. Thomas specializes in molecular genetic mechanisms with emphasis on single nucleotide polymorphisms (SNPs), alternative polyadenylation, and non-coding RNA regulation including microRNAs and circular RNAs. His methodological expertise spans genome-wide association studies (GWAS), genotype quality control, and functional analysis of genetic variants. Current projects integrate multi-omics approaches to dissect gene-environment interactions in complex diseases. Analysis of his 2023-2025 publications reveals consistent focus on large-scale genetic epidemiology using UK Biobank and HUNT Study datasets. Key disease targets include psoriasis, kidney disorders, and neurological conditions, with emerging work on trace element genetics. His collaborative studies frequently appear in high-impact journals like Science and Nature Communications , emphasizing translational applications of genetic findings. No scientific awards were documented in the source material. While the text confirms active research leadership, it contains no details about student supervision or specific grant funding mechanisms. His laboratory work appears integrated within NTNU's molecular biology infrastructure. Dr. Thomas operates within NTNU's K.G. Jebsen Center for Genetic Epidemiology framework, contributing to population-scale genomic initiatives. His computational work leverages the HUNT Study biobank and collaborates with international consortia on cross-disease genetic analyses.

• Gene regulation
• Non-coding RNAs
• Genome-wide association studies (GWAS)
• +۳ مورد دیگر

Nishana Mayilaadumveettil is an Assistant Professor at the School of Biology, Indian Institute of Science Education and Research Thiruvananthapuram , focusing on chromatin organization, nuclear structure, and their roles in disease mechanisms. Her lab investigates how chromatin interactions regulate cellular processes and contribute to cancer and aging. Education : PhD in Biochemistry (IISc Bangalore), MSc in Microbiology (Kannur University), BSc in Microbiology (Kannur University) Research Interests : Chromatin dynamics, epigenetic regulation, DNA repair, cancer genomics Her work spans chromosomal interactions, 3D genome organization, and the role of non-B DNA in translocations. Recent studies highlight her contributions to understanding RAG complex regulation and CTCF-RNA interactions. Scientific Awards : ICMR Investigator-Initiated Research Proposal (2024) CSIR ASPIRE Grant (2024) SERB Start-up Grant (2023) Best Oral Presentation at NYU Langone (2020) National Cancer Center Grant (2017) Multiple Best Poster Awards (2013, 2012, 2011) She leads the Chromatin Biology Lab (CBL) at IISER TVM, mentoring students in chromatin research and utilizing multi-omics approaches for cancer studies.

• Chromatin Biology
• Nuclear Organization
• Genomic Regulation
• +۴ مورد دیگر