جستجوی استاد راهنمای دانشگاهی

• Drug Delivery
• Nanomedicine
• Biopharmaceutics
• +۷ مورد دیگر

Dr. Shyh-Dar Li is a Professor and Tong Louie Chair in Pharmaceutical Sciences at the University of British Columbia's Faculty of Pharmaceutical Sciences, where he also serves as Chair of Nanomedicine and Chemical Biology. With a BSc in pharmacy from National Taiwan University (1998) and PhD in pharmaceutical sciences from UNC Chapel Hill (2008), followed by postdoctoral training at UC San Diego's Moores Cancer Center (2009), Dr. Li has established himself as a leading researcher in advanced drug delivery systems. His research focuses on developing innovative nanomedicine platforms for targeted delivery of biological therapeutics including peptides, proteins, antibodies, and nucleic acids. Dr. Li's laboratory has pioneered several novel drug delivery approaches, particularly in lipid-based nanoparticles, phospholipid-free vesicles, and polymer systems for cancer immunotherapy, pain management, and protein delivery. His work bridges fundamental nanotechnology with translational applications for difficult-to-treat diseases. Analysis of his recent publications reveals a strong emphasis on tumor microenvironment modulation, endosomal escape mechanisms for nucleic acid delivery, and non-invasive delivery routes for protein therapeutics. His research demonstrates increasing sophistication in nanocarrier engineering, with recent work incorporating machine learning approaches to optimize nanoparticle design and expanding into immunomodulatory therapies that harness the body's immune system to fight cancer. Scientific Recognition: 2014 AFPC New Investigator Award 2013 AAPS New Investigator Award in Pharmaceutics and Pharmaceutical Technologies 2013 CIHR New Investigator Award 2013 CSPS Early Career Award 2012 Prostate Cancer Foundation Young Investigator Award Dr. Li's research program has been consistently supported by major Canadian funding agencies including CIHR, NSERC, and MITACS. He actively collaborates across disciplines and accepts graduate students into his research program, focusing on cutting-edge approaches to overcome biological barriers in drug delivery. His laboratory, the Laboratory of Targeted Drug Delivery and Nanomedicine, serves as a hub for innovation in pharmaceutical nanotechnology.

Vadim Cherezovمشاهده پروفایل

استاد

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +۳ مورد دیگر

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

• Computational Neuroscience
• Computational Psychiatry
• Neuroimaging
• +۳ مورد دیگر

John D. Murray is the Gregg L. Engles Associate Professor of Psychological and Brain Sciences at Dartmouth College and an Adjunct Associate Professor of Psychiatry at Yale School of Medicine. He holds a PhD in Physics from Yale University (2013) and a BS in Physics and Mathematics from Yale (2006). His research focuses on computational neuroscience and computational psychiatry, with secondary appointments in Physics and Neuroscience at Yale until 2023. His work integrates computational modeling, neuroimaging, and systems neuroscience to study decision-making processes, cortical organization, and psychiatric disorders. Collaborators include prominent researchers like Dr. John Krystal and Dr. Anticevic. Research interests include hierarchical brain organization, neuroimaging analysis techniques, and pharmacological effects on neural circuits. His lab (Murray Lab) develops computational tools like PsychRNN for cognitive task modeling. Notable contributions include linking transcriptomic data to neuroimaging patterns and modeling LSD’s effects on brain topography. He has been featured in YaleNews and Nature Communications for innovations in mapping mental illness variability and neural circuit dynamics. Grants and collaborations span translational neuroscience, addiction, and PTSD research through partnerships with Yale’s Center for Biomedical Data Science and VA National Center for PTSD. His interdisciplinary approach bridges physics, computer science, and clinical psychiatry to advance understanding of brain function and dysfunction.

Aditi Dasمشاهده پروفایل

استاد

• Biochemistry and Chemical biology of Lipids
• Mechanism of Membrane proteins in Nanodiscs
• Enzymology of metalloproteins
• +۵ مورد دیگر

Aditi Das is a Full Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, College of Sciences. She leads the Das Laboratory, which focuses on the biochemistry and chemical biology of lipids, particularly studying cytochrome P450 enzymes and their role in lipid metabolism, endocannabinoid systems, and inflammatory pathways. Her educational background includes: B.Sc. in Chemistry from St. Stephen's College M.Sc. in Chemistry from Indian Institute of Technology, Kanpur (I.I.T) Ph.D. in Chemistry from Princeton University Postdoctoral research at Northwestern University (NSF-NSEC fellow) and Beckman Institute for Advanced Science and Technology, University of Illinois UC Professor Das's research interests center around understanding the physiological role of lipids in sustaining homeostasis and their implications in disease states such as neurodegenerative disorders, cancer, and cardiovascular diseases. Her laboratory specializes in: Enzymology of cytochrome P450s, particularly CYP2J2 epoxygenase Metabolism of ω-3 and ω-6 fatty acids and their derivatives Minor cannabinoid metabolism by cytochrome P450 enzymes Discovery of novel anti-inflammatory lipid metabolites and endocannabinoids Mechanistic studies of membrane proteins using nanodisc technology Her work bridges biochemistry, chemical biology, and pharmacology to uncover novel therapeutic targets related to lipid signaling pathways. Analysis of Professor Das's recent publications (2023-2025) reveals a strong focus on cannabinoid metabolism by cytochrome P450 enzymes, with particular emphasis on how these metabolic processes generate bioactive compounds that interact with the endocannabinoid system. Her research increasingly explores the therapeutic potential of omega-3 derived endocannabinoid epoxides in inflammatory and neurodegenerative conditions. The use of nanodisc technology for studying membrane proteins in near-native environments remains a consistent methodological thread throughout her work, enabling detailed mechanistic insights into enzyme function. Professor Das has received numerous prestigious awards recognizing her research excellence and teaching: 2024 NIH Outstanding Researcher Award (MIRA R35) for established investigators 2024 Vasser Woolley Faculty Fellowship 2023 Plenary Lecture at the International Society of the Study of Xenobiotics (ISSX) 2021 E.L.R. Stokstad Award 2019-2021 List of Teachers Ranked as Excellent 2019 Eicosanoid Research Foundation Young Investigator Award 2019 Zoetis Research Excellence Award 2019 Mary Swartz Rose Young Investigator Award 2015 National Scientist Development Award from the American Heart Association 2022 El Sohly Award from the American Chemical Society Professor Das actively mentors a diverse group of students and postdoctoral researchers, with several former lab members now holding faculty positions or working at prestigious institutions. Her laboratory has secured significant funding from NIH, NSF, and other sources to support research on lipid metabolism, cannabinoid pharmacology, and membrane protein biochemistry. Notable grants include an NIH R35 Outstanding Investigator Award (MIRA), an NIH R21 grant from NIDA, and multiple collaborative grants with other research groups. The Das Laboratory operates within the Petit Institute of Bioengineering and Biosciences (IBB) at Georgia Tech, utilizing state-of-the-art facilities for biochemical and biophysical studies. The lab specializes in nanodisc technology to study membrane proteins in near-native environments, with particular expertise in cytochrome P450 enzymes and their interactions with lipid substrates. Recent work has expanded into collaborative projects involving lipidomics, structural biology, and translational applications of lipid signaling research.

Istvan Modyمشاهده پروفایل

استاد

• Neuroscience
• Neurology
• Pharmacology
• +۱۲ مورد دیگر

Istvan Mody is a Professor at the University of California, Los Angeles (UCLA) with appointments in the Department of Neurology and Department of Physiology . His research focuses on synaptic signaling in health and disease, including mechanisms of GABAergic transmission, calcium homeostasis, and their roles in neurological disorders such as epilepsy, Alzheimer's disease, Huntington's disease, stress, alcoholism, and postpartum depression. He utilizes advanced techniques like patch-clamp electrophysiology, neuroanatomical and immunohistochemical methods, and molecular biology in animal models and human brain tissue . Research Interests: Dr. Mody investigates the physiology, pharmacology, and pathology of synaptic transmission and extrasynaptic receptor activation , with a particular emphasis on GABA(A) receptors and their subunit-specific modulation. His work explores how disruptions in excitation-inhibition balance contribute to neurological diseases, including mechanisms of tonic inhibition , calcium signaling , and neurosteroid interactions . He also studies the effects of chronic stress and hormonal fluctuations on neural excitability and behavior. Publications Trends: Recent studies highlight his work on gamma oscillations in Alzheimer's models, microglial dynamics , and rehabilitation strategies for stroke. His lab develops optical tools like dqGEVI for neuronal activity monitoring and investigates human brain organoids to model network dysfunction in epilepsy and intellectual disability. Laboratory Location: 635 Charles Young Dr S, Los Angeles, CA 90095, United States.

Markus Heiligمشاهده پروفایل

استاد

• Addiction Neuroscience
• Alcohol Dependence
• Neuropharmacology
• +۴ مورد دیگر

Markus Heilig is a Professor of Psychiatry and Head of the Department of Biomedical and Clinical Sciences (BKV) at Linköping University. He serves as Director of the Center for Social and Affective Neuroscience (CSAN), integrating basic and clinical neuroscience to address addictive and affective disorders. His work bridges neuropharmacology, molecular psychiatry, and clinical trials. Linköping University (Current) Center for Social and Affective Neuroscience (CSAN) (Director) Wallenberg Center for Molecular Medicine (Collaborator) His research focuses on alcohol dependence mechanisms, stress-neurotransmitter interactions (e.g., CRF, substance P, endocannabinoids), and personalized medicine approaches. Using animal models and human neuroimaging (fMRI), his lab explores epigenetic changes in frontal lobe and amygdala neurons that drive compulsive alcohol use. Recent publications highlight his work on endocannabinoid modulation for PTSD treatment, neural correlates of reward choices, and pharmacological interventions targeting GABA and opioid receptors. His studies often combine brain imaging, behavioral analysis, and pharmacology. Scientific awards include the 2019 Wallenberg Clinical Scholar grant and 2017 CAN/Nordic Drugs prizes. Heilig's research is supported by Vetenskapsrådet (SEK 57 million center funding) and international donations like the Andrew J. Bock Memorial Fund.

Ilse Dewachterمشاهده پروفایل

استاد

• Alzheimer's Disease
• Neurodegenerative Diseases
• Therapeutic Development
• +۶ مورد دیگر

Prof. Ilse Dewachter is the head of the Biomed Neuroscience research group at Hasselt University (UHasselt), specializing in Alzheimer’s therapy and prevention for over 25 years. Her work focuses on multi-targeted therapies targeting tau, inflammation, and ApoE, alongside pioneering research into disease prevention via blood-based biomarkers. Recent studies explore a protective APOE3ch mutation that halted Alzheimer’s progression in a patient, offering hope for new treatments. Research Interests: - Alzheimer’s disease mechanisms (Abeta, tau, inflammation) - Multi-target therapies and biomarker development - Neurodegenerative disease prevention strategies - Genetic mutations impacting disease progression Articles Overview: Her most recent work (2025-2022) addresses neuroinflammation, tau propagation models, and AI-driven neuroimaging. Key themes include APOE genetics, blood-brain barrier dynamics, and exercise impacts on cognition. Funding & Grants: Current projects require significant investment for advanced biomarker equipment and clinical trials. A notable €300,000 grant funded research on brain lipid metabolism’s role in Alzheimer’s. Labs & Teams: Leads the BIOMED Neuroscience group at UHasselt, collaborating internationally on preclinical models and drug development.

Rodolfo J. Floresمشاهده پروفایل

استادیار

• Behavioral Neuroscience
• Neuromodulators
• Prefrontal Cortex Function
• +۳ مورد دیگر

Dr. Rodolfo J. Flores serves as an Assistant Professor in the Department of Psychology within the College of Liberal Arts at the University of Texas at El Paso (UTEP). His primary research investigates neuromodulator function in the prefrontal cortex, with emphasis on acetylcholine and dynorphin systems during motivational conflict, stress responses, and addiction pathways. He employs advanced optogenetic and biosensor technologies to dissect neural circuitry underlying psychiatric conditions. Dr. Flores earned his Ph.D. in Social Cognitive and Neuroscience from UTEP in 2019, followed by postdoctoral training at the National Institute of Mental Health (NIMH). His work bridges molecular neuroscience with behavioral outcomes, focusing on how stress and substance exposure alter prefrontal cortical function. His research portfolio demonstrates consistent high-impact publication in top neuroscience journals including Nature Neuroscience , Neuron , and Psychoneuroendocrinology . Current work examines opioid neuropeptide dynamics, nicotine-alcohol interactions, and sex-specific hormonal influences on addiction behaviors. Methodologically, he specializes in genetically encoded biosensors and circuit-level manipulations to study threat processing and reward pathways. Dr. Flores teaches graduate and undergraduate courses including PSYC 4341 (Motivation & Emotion), thesis/dissertation supervision (PSYC 5395/6395), and research applications courses. His lab actively trains students through undergraduate research (RSRC 4033) and independent study opportunities (PSYC 4352).

Tyler Johnsonمشاهده پروفایل

دانشیار

• Natural Products Chemistry
• Bioorganic Chemistry
• Medicinal Chemistry
• +۲ مورد دیگر

Tyler Johnson, PhD, is an Associate Professor in the Department of Natural Sciences and Mathematics at Dominican University of California's School of Health and Natural Sciences. His expertise lies in Natural Products Chemistry , Bioorganic Chemistry , and Medicinal Chemistry , with a focus on biomedical applications. Johnson's research emphasizes discovering therapeutic lead compounds and molecular probes from marine and terrestrial natural products. His research team investigates chemotypes like mycothiazole , zampanolide , fijianolide , and latrunculin from Indo-Pacific marine sponges. These compounds exhibit potent cytotoxicity (IC50 1~5 nM) against cancer cell lines through mechanisms including microfilament disruption , mitochondrial complex I inhibition , and microtubule stabilization . Current work explores mycothiazole as a molecular probe for mitochondrial aging. Key publications span 2024-2002, covering topics from sponge-derived anticancer agents to inflammation modulation and environmental toxicology. Johnson's laboratory engages in large-scale natural product isolation, spectroscopic validation, and semi-synthetic medicinal chemistry to optimize therapeutic leads. His work integrates undergraduate and graduate students into interdisciplinary biomedical research.

Teresa Puthusseryمشاهده پروفایل

دانشیار

• Retinal Neurobiology
• Neurophysiology
• Retinal Degeneration
• +۳ مورد دیگر

Dr. Teresa Puthussery is an Associate Professor in the School of Optometry & Vision Science at the University of California, Berkeley. Her research focuses on retinal neurobiology and neurophysiology, investigating how visual signals are encoded in healthy retinas and disrupted during degeneration. She uses advanced techniques like patch-clamp electrophysiology, immunohistochemistry, and microscopy to study retinal circuits, neurotransmitter receptors, and ion channels. Dr. Puthussery teaches courses on vision science anatomy, physiology, and problem-based learning, including VISION SCIENCE 206B/C and 260C. Her research explores questions such as how retinal neurons extract motion/spatial details, how photoreceptor mutations cause degeneration, and how inner retinal circuits adapt post-photoreceptor loss. Recent work includes studies on ON-type direction-selective ganglion cells, optogenetic therapy for vision restoration, and calcium dynamics in foveal ganglion cells post-degeneration. She collaborates on projects involving primate and rodent models, contributing to understanding retinal disease mechanisms and therapeutic targets. Dr. Puthussery’s lab (retinalab.berkeley.edu) emphasizes translational research, bridging basic science and clinical applications. Her work has been published in journals like Nature and Cell Reports , with a focus on retinal degeneration, synaptic plasticity, and optogenetic interventions. She actively participates in training future vision scientists through Berkeley’s Optometry program and oversees GSI affairs as a faculty advisor.

• Neurobiology
• Synaptic Plasticity
• Molecular Genetics
• +۷ مورد دیگر

Prof. Stephan J. Sigrist is a Full Professor of Genetics at the Institute of Biology, Free University of Berlin. His lab focuses on synaptic active zone architecture, neuroplasticity, and aging-related neurodegeneration. He leads the Collaborative Research Center 958 on Membrane Scaffolding and co-directs NeuroCure, a DFG Cluster of Excellence at Charité. Education: PhD in Molecular Genetics (1997) and Habilitation (2005) from the University of Göttingen. Positions: Einstein Professor (2014–present), Spokesperson CRC 958 (2012–present), and Co-Director NeuroCure (2009–present). Research explores presynaptic mechanisms using Drosophila and mouse models, combined with STED microscopy. Key contributions include discoveries of Bruchpilot's role in active zones and spermidine's protective effects against age-related synapse decline. Grants: Over €6 million in funding, including DFG CRCs, Einstein Foundation, and ERC Advanced Grant (2025). Awards: Einstein Professorship, Best Habilitation Award, EMBO/HFSP Fellowships. Collaborations span structural biology (e.g., Stefan Hell), neurophysiology (David DiGregorio), and aging research (Frank Madeo).

Anna Mathia Klawonnمشاهده پروفایل

دانشیار

• Neuroscience
• Neuroimmunology
• Affective Disorders
• +۶ مورد دیگر

Anna Mathia Klawonn is an Associate Professor affiliated with three units at Aarhus University: the Danish Research Institute of Translational Neuroscience (DANDRITE), the Department of Biomedicine, and the Department of Molecular Biology and Genetics - Neurobiology. As a group leader at DANDRITE, she explores neural circuits and immune-to-brain signaling mechanisms regulating affective states through transgenic strategies and neurocircuitry techniques. Neuroscience Neuroimmunology Immune-to-Brain Signaling Affective Disorders Her research focuses on understanding how brain circuits and glial cells (microglia and astrocytes) contribute to affective states in both health and disease. Current projects investigate mechanisms in major depressive disorder and Parkinson's disease, emphasizing prostaglandin signaling, nicotinic receptor function, and striatal neuron modulation. Recent publications highlight her work in molecular neuroscience, neuropharmacology, and behavioral neuroscience. Key themes include cholinergic transmission in motivation, neuroimmune interactions in aversion, and reward/aversion circuitry. Her studies employ advanced neurocircuitry methods and transgenic models. In teaching, Klawonn is course responsible for the 3rd-semester Neuroscience course (10 ECTS) in the medical bachelor program. She actively engages in didactic development, frequently speaking about student motivation, flipped learning, and challenge-based learning. Klawonn leads the Klawonn Group at DANDRITE, with lab and office spaces in the Skou Building (Høegh-Guldbergs Gade 10, Aarhus C). Her work involves collaborations across neuroscience, neuroimmunology, and affective disease research.

Michelle CD Bridiمشاهده پروفایل

استادیار

• Neuroscience
• Synaptic Plasticity
• Sleep Research
• +۷ مورد دیگر

Michelle CD Bridi is an Assistant Professor in the Department of Neuroscience at West Virginia University School of Medicine , with a joint affiliation at the Rockefeller Neuroscience Institute . Her research integrates synaptic plasticity , sleep physiology , and neurological conditions to investigate dynamic synaptic regulation under typical and atypical states. Education: BS , McGill University, 2006 PhD , University of Pennsylvania, 2013 Research Focus: The Bridi Lab explores how daily oscillations in excitation/inhibition (E/I) balance are disrupted in Autism Spectrum Disorder (ASD) , aging , and post-stroke states . Current projects address: 1) synaptic adaptation to sleep/wake cycles, 2) E/I imbalance in neurodevelopmental disorders, and 3) molecular mechanisms maintaining neuronal firing rate homeostasis. Publication Trends: Recent work spans REM sleep plasticity , autism models , and neurodegenerative interventions , emphasizing synaptic oscillations , NMDA receptor pathways , and gene therapy applications. Collaborative efforts with Morgan Bridi's lab extend findings to stress and stroke contexts. Grants & Collaborations: Research is funded by NIH/NIGMS , BBRF , and NSF . The lab actively collaborates with cross-institutional teams and is recruiting postdocs and students for ongoing studies.

Rosalyn Moranمشاهده پروفایل

استاد

• Computational Neuroscience
• Computational Psychiatry
• Neurodegenerative Diseases
• +۵ مورد دیگر

Professor Rosalyn Moran is a Professor of Computational Neuroscience and Deputy Director of King's Institute for Artificial Intelligence at King's College London. She holds roles in the Department of Neuroimaging and School of Neuroscience within the Institute of Psychiatry, Psychology & Neuroscience. Her research focuses on computational neuroscience, computational psychiatry, and neurology, particularly integrating brain connectivity with algorithmic principles like the free energy principle. She explores neurotransmitter roles in decision-making and disease modeling, with applications in artificial intelligence and neurodegenerative disorders. Moran serves as an editor for Neuroimage and collaborates with leading institutions. Key projects include global neuroimaging initiatives (UNITY) and low-field MRI advancements in low-resource settings. Her work bridges Bayesian inference, AI, and neurobiology, with recent emphasis on pediatric neuroimaging and treatment-resistant psychosis. Education & Research Interests Rosalyn Moran's research spans computational psychiatry, neuroimaging techniques, and AI applications in healthcare. Her lab investigates serotonin and dopamine signaling, brain connectivity patterns, and predictive coding frameworks. Notable contributions include modeling NMDA receptor dysfunction in encephalitis and developing super-resolution MRI methods for global health contexts. Grants & Collaborations Funded projects include MRC Human Functional Genomics (2024-2028), NIHR Maudsley BRC (2022-2027), and Gates Foundation initiatives for low-field MRI enhancement. Collaborators include Karl Friston (UCL), Read Montague (Virginia Tech), and Klaas Enno Stephan (University of Zurich). Recent events include presenting the Free Energy Principle's role in generative AI (May 2023). Labs & Teams Her lab focuses on computational psychiatry and AI-driven neuroimaging solutions, collaborating with the King’s Global Health Institute to advance medical imaging accessibility in low-income regions.

Anna G Orrمشاهده پروفایل

استادیار

• Neuroscience
• Neurodegenerative Diseases
• Astrocyte Biology
• +۵ مورد دیگر

Anna G Orr serves as Nan and Stephen Swid Assistant Professor of Frontotemporal Dementia Research and Assistant Professor of Neuroscience at Weill Cornell Medical College's Brain and Mind Research Institute since 2016, leading pioneering research on astrocyte biology in dementia pathogenesis. Her educational background includes: Ph.D. from Emory University (2008) B.S. from Allegheny College (2002) Dr. Orr's research program centers on astrocytic-neuronal interactions , mitochondrial signaling , and neuroimmune mechanisms through three interconnected pathways: neuroimmune , oxidative , and G protein-coupled signaling . Her lab investigates how these mechanisms influence neuroinflammation, protein aggregation, synaptic function, and behavioral outcomes in dementia, with parallel therapeutic discovery efforts targeting astrocytic pathways for novel dementia treatments. Analysis of her 15 most recent publications (2025-2010) reveals escalating focus on astrocyte-specific dementia mechanisms , particularly mitochondrial ROS signaling, sex-dimorphic memory effects, TDP-43 pathology interactions with antiviral pathways, and lipid dysregulation in neurodegeneration. Her work consistently bridges molecular discoveries with therapeutic applications, demonstrating increasing NIH funding support for translational approaches. Key scientific recognitions include: NIH K99/R00 Pathway to Independence Award (2017) Leon Levy Fellowship in Neuroscience (2021) Nan and Stephen Swid Endowed Professorship (2021) Outstanding Neuroscience Teaching Award (2021) Dr. Orr actively mentors eight trainees across career stages, including Ph.D. candidates Evelyn Hardin and Constance Zhou, while securing major NIH grants as Principal Investigator for projects like Uncovering Dementia-Related Lipid Alterations in Astrocytes (NIA 2024-2026) and Mitochondrial Complex III Free Radicals in Dementia Pathology (NIA 2020-2026), alongside collaborative awards from the Alzheimer's Association. Her Orr Lab maintains a dual focus on mechanistic astrocyte biology and therapeutic translation, with current projects examining astrocytic TDP-43 dysregulation, mitochondrial complex III signaling, and sex-specific memory mechanisms using advanced in vivo techniques and disease models.