جستجوی استاد راهنمای دانشگاهی

Steffen Klamtمشاهده پروفایل

پژوهشگر ارشد

• Metabolic Engineering
• Systems Biology
• Computational Modeling
• +۲ مورد دیگر

Dr.-Ing. Steffen Klamt leads the Research Group 'Analysis and Redesign of Biological Networks' at the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg, Germany, where he has been employed since 1998. He received his Diplom-Systemwissenschaftler degree from the University of Osnabrück in 1998 and his Dr.-Ing. from the University of Stuttgart in 2005. His research focuses on computational systems biology with emphasis on metabolic engineering, biochemical networks analysis, and bioprocess optimization. He develops computational tools like CellNetAnalyzer for network analysis and StrainDesign for metabolic engineering applications. Key research areas include constraint-based modeling, minimal cut sets analysis, and dynamic optimization of metabolic processes. His recent publications demonstrate strong focus on multi-stage bioprocess optimization, enzyme cascade engineering, and novel strain development strategies for chemical production. Common themes include ATP manipulation strategies, thermodynamic constraints in metabolism, and integration of experimental data with computational models. Scientific Awards: Ernst Dieter Gilles Lecture Award Ernst Dieter Gilles Fellowship He leads a research group developing computational methods for metabolic network analysis and maintains collaborations with experimental groups for model validation and application. The group develops open-source software tools widely used in systems biology research.

Helma Wennemersمشاهده پروفایل

استاد

• Organic Chemistry
• Chemical Biology
• Peptide Chemistry
• +۵ مورد دیگر

Prof. Dr. Helma Wennemers serves as a Full Professor at ETH Zurich's Department of Chemistry and Applied Biosciences, leading the Laboratory for Organic Chemistry. Her research group operates from HCI H 313 at Vladimir Prelog Way 1-5/10 in Zurich, Switzerland, with active teaching responsibilities including Organic Chemistry I and Chemical Biology - Peptides for the Fall 2025 semester. Her research program centers on the intersection of organic chemistry and chemical biology , with particular emphasis on collagen triple helix engineering , peptide-catalyzed asymmetric synthesis , and development of chemical tools for tissue remodeling diagnostics . Key focus areas include designing hyperstable collagen heterotrimers for fibrosis monitoring, creating fluorophore-based probes for collagen cross-linking visualization, and pioneering organocatalytic methodologies for complex heterocycle synthesis. Her group actively explores how hydrophobic modifications and proline derivatives influence collagen stability and cellular uptake mechanisms. Analysis of her 15 most recent publications (2024-2025) reveals three dominant research trajectories: (1) collagen structural engineering for biomedical applications, (2) innovative peptide/organocatalysis enabling stereoselective transformations, and (3) chemical probe development targeting tissue remodeling processes. These works consistently integrate synthetic chemistry with biological validation, demonstrating translational potential in fibrosis diagnostics and regenerative medicine. While specific grant details aren't provided in available sources, her research program clearly supports advanced laboratory infrastructure including peptide synthesis facilities and photochemical reaction systems like the ETHos photoreactor. Her group maintains strong industry and clinical collaborations evident in applications targeting liver cancer cells and prostate cancer diagnostics. The Laboratory for Organic Chemistry functions as an interdisciplinary hub where synthetic organic chemists collaborate with biologists to develop collagen-based diagnostic platforms and catalytic systems. Current projects focus on lysyl oxidase-responsive probes for real-time tissue monitoring and engineered peptide catalysts for sustainable chemical synthesis under environmentally relevant conditions.

Michael Feigمشاهده پروفایل

استاد

• Molecular Dynamics
• Computational Biophysics
• Protein Structure and Dynamics
• +۳ مورد دیگر

Michael Feig serves as Professor in the Department of Biochemistry & Molecular Biology at Michigan State University, leading the Feig Lab within the BioMolecular Science Gateway initiative. His research bridges computational modeling and molecular biology to investigate protein behavior in cellular contexts, with particular emphasis on molecular dynamics simulations and machine learning applications. His academic background includes: Ph.D. (1999) from the University of Houston M.S. (1994) from Technical University of Berlin Feig's research program focuses on computational biophysics of protein systems, specializing in molecular dynamics simulations of crowded cellular environments, bacterial microcompartments, and intrinsically disordered proteins. His lab develops advanced modeling techniques including coarse-grained approaches (COCOMO2) and machine learning frameworks to predict protein properties and conformational landscapes. Current work explores temperature-dependent structural ensembles, enzyme cargo loading mechanisms in engineered microcompartments, and biomolecular condensate physics under shear flow. Analysis of his 15 most recent publications (2024-2025) reveals three dominant research thrusts: (1) integration of deep learning with molecular dynamics for protein structure prediction, (2) engineering of bacterial microcompartments for synthetic biology applications, and (3) fundamental studies of macromolecular crowding effects on diffusion and phase separation. His work consistently emphasizes methodological innovation with biological relevance, notably through enhancements to the CHARMM simulation platform. His scientific recognition includes: Alfred P. Sloan Fellowship (2005) As principal investigator of the Feig Lab, he directs research teams in computational biophysics projects supported by active funding mechanisms. While specific grant details aren't provided, his continuous publication pipeline and lab infrastructure indicate sustained research support. His mentorship spans graduate students in the Cell & Molecular Biology Program, with recent work involving multi-institutional collaborations on bacterial microcompartment engineering and protein phase separation. The Feig Lab operates at the intersection of high-performance computing and molecular biology, maintaining strong connections with experimental groups for method validation. Current initiatives include developing generative models for temperature-dependent protein conformations and investigating cytoplasmic protein capture mechanisms in microcompartments, with potential applications in metabolic engineering and nanobiotechnology.

Susie Daiمشاهده پروفایل

استاد

• PFAS Remediation
• CO2 Conversion
• Synthetic Biology
• +۶ مورد دیگر

Susie Dai is a Professor in the Department of Chemical and Biomedical Engineering at the University of Missouri, with a laboratory located at the Bond Life Sciences Center. Her research bridges chemistry, biology, and engineering to address critical environmental and sustainability challenges. Education: PhD in Chemistry from Duke University; Certificate in Biomedical Engineering from Duke University; Certificate in Regulatory Science from Texas A&M University; BS in Chemistry from Fudan University Dr. Dai specializes in biological and material engineering, carbon waste conversion, contaminant remediation, and synthetic biology. She is developing RAPIMER, a lignin-based fungal scaffold for PFAS removal, and pioneering electro-microbial systems to convert CO2 into bioplastics and biofuels. Her work focuses on scalable, sustainable solutions for environmental pollutants and carbon utilization. Recent research trends include creating biomimetic materials for sustainable packaging, optimizing lignocellulosic biorefineries, and designing lignin-derived photocatalysts. She leads projects funded by Tito's Handmade Vodka's philanthropic arm for PFAS remediation and collaborates with the NSF Engineering Research Center CURB at Washington University in St. Louis. At Mizzou, Dai integrates engineering and life sciences, leveraging both Mizzou Engineering and Bond Life Sciences Center's resources. Her interdisciplinary approach combines electrochemistry, microbial engineering, and social impact analysis to advance circular bioeconomy solutions.

Kunihiko Kanekoمشاهده پروفایل

استاد

• Theoretical Biophysics
• Complex Systems
• Chaos
• +۶ مورد دیگر

Kunihiko Kaneko is a Professor at the Niels Bohr Institute, University of Copenhagen, with a distinguished career in theoretical biophysics and complex systems. He received his PhD and MSc in Physics from the University of Tokyo, and has held leadership roles at the Universal Biology Institute and Center for Complex Systems Biology. PhD Physics, 1984 - University of Tokyo MSc Physics, 1981 - University of Tokyo His research spans five primary areas: Universal Biology, Evolutionary Constraints, Ecosystem Dynamics, Neural Cognition, and Universal Anthropology. He has published extensively on multi-level consistency principles, dimensional reduction in biological systems, and reciprocity between robustness and plasticity across scales. Recent publications show strong focus on microbial ecosystems (2025), evolutionary game theory (2025), neural modular architectures (2024), and dimensional reduction in cellular systems (2024). His work bridges physics and biology through dynamical systems theory applied to diverse phenomena from protocells to human societies.

Parisa Hosseinzadehمشاهده پروفایل

استادیار

• Protein Design
• Computational Biochemistry
• Biosensors
• +۳ مورد دیگر

Parisa Hosseinzadeh is an Assistant Professor in the Department of Bioengineering at the University of Oregon. Her research focuses on computational protein design and structure-guided rational protein/peptide engineering, with applications in enzyme design, biosensors, and biomedical solutions. She holds a B.Sc. from the University of Tehran, a Ph.D. from the University of Illinois (advisor: Yi Lu), and a postdoc at the University of Washington in David Baker's lab. Her lab emphasizes interdisciplinary approaches at the intersection of computer science, chemistry, and biology, prioritizing diversity and inclusion in STEM. Key projects include designing cyclic peptides as enzyme inhibitors, developing methods for tuning redox potentials in metalloproteins, and creating tools to combat biomedical challenges. Lab members include postdocs, graduate students (e.g., Noora Azadvari, Andrew Powers), and undergraduates. Notable achievements include NSF grants, the Baxter Foundation Award, and the Hans Horse Meyer Award. The lab also emphasizes mentorship, collaborative culture, and outreach initiatives.

Prashant Maliمشاهده پروفایل

استاد

• Genome Engineering
• RNA Editing
• Stem Cell Research
• +۴ مورد دیگر

Prashant Mali is a Professor in the Department of Bioengineering at the University of California, San Diego . His research bridges genome engineering, RNA biology, and biomedical applications, with a focus on CRISPR-Cas systems and ADAR-mediated RNA editing. Education : Ph.D. in Bioengineering Key Affiliations : UC San Diego, Altman Clinical and Translational Research Institute Dr. Mali's work centers on CRISPR-Cas9 technology , RNA editing , and human pluripotent stem cells . His lab develops tools for programmable gene regulation, synthetic lethal screens, and metabolic pathway analysis in disease contexts. Recent publications highlight innovations in circular RNA engineering , ADAR activity mapping , and metabolic reprogramming in cancer . His team employs multi-omics approaches and in vivo models to translate genome editing into clinical applications. Students and Collaborators Current Lab Members : Sami Nourreddine (Postdoc), Amir Dailamy (Graduate), Andrew Portell (Graduate), Michael Tong (Graduate) Alumni : Kyle Ford (PhD 2022), Nathan Palmer (PhD 2022), Udit Parekh (PhD 2021) Research Themes CRISPR Screens : Synthetic lethal interactions, oncogenic pathways, metabolic vulnerabilities RNA Editing : ADAR engineering, circular guide RNAs, clinical translation Tissue Engineering : Vascularized organoids, cardiac maturation, ex vivo models

Forest M. Whiteمشاهده پروفایل

استاد

• Metastasis
• Precision Medicine
• Immunology & Immunotherapy
• +۷ مورد دیگر

Professor Forest M. White is a faculty member at MIT's Department of Biological Engineering , where he holds the Ned C. and Janet Bemis Rice Professorship . He is affiliated with the Koch Institute for Integrative Cancer Research and the MIT Center for Precision Cancer Medicine . His research focuses on systems biology and computational modeling of signaling networks in cancer, particularly at the tumor-immune interface . Education: B.S. in Chemistry (Framingham State College, 1993), Ph.D. in Analytical Chemistry (Florida State University, 1997) Professional Journey: Postdoc at University of Virginia, Research Scientist at MDS Proteomics, Assistant Professor at MIT (2003), Mitsui Career Development Professor (2005-2008) White employs high-resolution mass spectrometry to analyze protein phosphorylation and antigen presentation in cancer models, complementing genomic/transcriptomic approaches. His lab has identified chronic stress response enzymes linking high-fat diets to metabolic dysfunction and discovered resistance mechanisms in cancer therapies through phosphoproteomics . Scientific Awards: Mitsui Career Development Professorship (2005-2008) Ruth and Joel Spira Award for Excellence in Teaching (2010) Fellowship from the Ludwig Center at MIT The White Lab actively recruits trainees (undergraduates, graduates, postdocs) through programs like MSRP , CSB , and HST . His work is supported by grants from Break Through Cancer and Ludwig Center , with collaborations spanning Cima Lab , Swanson Biotechnology Center , and MIT Koch Institute .

Judy Hartمشاهده پروفایل

دانشیار

• Renewable Energy Materials
• Photocatalysis
• Solar Cells
• +۵ مورد دیگر

Associate Professor Judy Hart is a materials scientist at the School of Materials Science & Engineering, UNSW Sydney , specializing in the development of semiconducting materials for renewable energy applications. Her work integrates computational (DFT) and experimental approaches to understand composition-property relationships in systems like solid solutions , heterostructures , and doped materials for photocatalysis and solar cells . She leads projects funded by ARC Discovery and Linkage grants , including work on photo-electro-catalysis systems and stabilizing ceramic materials . Education: PhD in Materials Engineering (Monash University, 2007), BEng (Materials) (Monash, 2002) Professional Experience: Senior Lecturer (UNSW, 2017–), Lecturer (UNSW, 2013–2017), University of Bristol (2007–2012) Research Interests Her research focuses on designing materials for renewable energy , particularly photoelectrochemical water splitting and organic oxidation reactions . Key areas include Density Functional Theory (DFT) , defect engineering , band gap tuning , and nanostructured materials . She investigates ferroelectric polarization effects , metal oxide heterostructures , and stability of battery components , with applications in hydrogen production , CO2 conversion , and advanced battery materials . Scientific Awards Ramsay Memorial Fellowship (University of Bristol, 2007–2009) Teaching Contributions She is co-author of the 1st Australian & New Zealand edition of "Materials Science and Engineering: An Introduction" , and teaches courses on computational materials science , corrosion-resistant surfaces , mechanical behavior of metals , and materials design .

Christos Tapeinosمشاهده پروفایل

مدرس

• Pharmaceutical Nanotechnology
• Drug Delivery Systems
• Brain Diseases (Glioblastoma, Neuroinflammation)
• +۵ مورد دیگر

Christos Tapeinos is a Lecturer in Pharmaceutical Sciences at the University of Manchester, specializing in pharmaceutical nanotechnology for treating brain diseases (e.g., glioblastoma, neuroinflammation) and pancreatic cancer. His research focuses on developing smart nanomedicines, advanced in vitro models (e.g., fluidic systems mimicking brain environments), and stimuli-responsive nanomaterials to overcome biological barriers like the blood-brain barrier. He leads the development of skin-mimicking models for subcutaneous drug delivery as a Co-Investigator in the HALo program. Education: Docent in Pharmaceutical Nanotechnology (2022) PhD in Materials Science (2013) MSc in Materials Science (2010) BSc in Materials Science (2006) Research Interests: Drug delivery systems, nanoparticle engineering, in vitro disease models, biomimetic materials, and translational nanomedicine. He integrates nanotechnology with precision medicine to address complex diseases. Recent Articles Trends: Focus on nanoparticle-cell interactions, phototherapy systems, graphene-cerium oxide hydrogels, and targeted theranostics. Highlights include ROS-scavenging systems and multi-stage nanovectors for CNS pathologies. Awards: Marie Skłodowska-Curie Actions Fellowship. Grants/Projects: Supported by EPSRC, The Royal Society, and Translation Manchester. Active in the Hub for Long-Acting Technologies (2024–2030). Labs/Teams: Leads research groups developing fluidic BBB models, skin-mimicking drug diffusion systems, and nanomaterial-based therapies.

• Biotechnology
• Biocatalysis
• Enzyme Engineering
• +۴ مورد دیگر

Pedro Carlos De Barros Fernandes is an Associate Professor at Universidade Lusófona , Deputy Director of the 1st cycle in Biotechnology, and an integrated researcher at the Institute of Bioengineering and Biosciences (iBB-IST). He holds a PhD in Biotechnology (1999) and a Master in Biotechnology/Biochemical Engineering (1994) from Universidade Técnica de Lisboa (IST), along with a Chemical Engineering degree from IST (1989). A member of the Order of Engineers (ID 24667), he co-founded Biotrend, a Portuguese bioprocess development company. Education PhD in Biotechnology (1999), Universidade Técnica de Lisboa MSc in Biotechnology (1994), Instituto Superior Técnico BSc in Chemical Engineering (1989), Instituto Superior Técnico Research Interests span biocatalysis, enzyme immobilization for food and pharmaceutical applications, marine biotechnology, microfluidic device development for biosensing, and steroid bioconversions using mycobacterial systems. His work integrates process engineering principles with sustainable bioprocessing techniques. Publication Trends show a focus on microreactor technology, enzyme stabilization in non-conventional media, marine-derived biocatalysts, and food waste valorization. Key themes include biocatalytic process intensification, aqueous two-phase systems for biomolecule purification, and sustainable carbon sources for biopolymer production. Scientific Awards UTL/Santander Totta Scientific Award in Biological Engineering (2011) Advising has included supervision of 5 doctoral theses and over 32 master’s theses. His expertise extends to peer-reviewing scientific articles and evaluating R&D projects. Labs & Teams are associated with iBB-IST (Institute of Bioengineering and Biosciences) and BioRG (Universidade Lusófona), with contributions to the Ciência Viva program for science dissemination.

Kyu Y. Rheeمشاهده پروفایل

استاد

• Tuberculosis
• Antibiotic Resistance
• Metabolomics
• +۳ مورد دیگر

Kyu Y. Rhee is a Professor of Medicine and Professor of Microbiology and Immunology at Weill Cornell Medical College . His research focuses on Mycobacterium tuberculosis , with emphasis on metabolic pathways , antibiotic resistance mechanisms , and drug development . Research highlights include: Multi-omic approaches to TB drug discovery Mechanistic studies of antibiotic action Deciphering TB transmission genetics Metabolomics-driven target identification Current funding includes: Bill & Melinda Gates Foundation : AI/ML-assisted bacterial permeability platform National Institute of Allergy & Infectious Diseases : UM1 TB drug regimen design consortium National Heart, Lung, & Blood Institute : Studies on M. tuberculosis PE/PPE proteins and fructose-induced cancer He has authored over 50 publications on TB metabolomics, drug development, and pathogen persistence. His work bridges systems biology , chemical biology , and clinical research to address antimicrobial resistance.

Youngchan Kimمشاهده پروفایل

مدرس

• Quantum Biology
• Biophotonics
• Bioimaging
• +۳ مورد دیگر

Dr. Youngchan Kim is a Lecturer in Quantum Biology at the University of Surrey , serving as Director of the Quantum Biology Doctoral Training Centre (QB-DTC). He is affiliated with multiple departments including the School of Biosciences, Advanced Technology Institute, and Quantum Sciences Group. PhD in Physics (2011), Korea Advanced Institute of Science and Technology MSc in Physics (2008), KAIST BSc in Physics (2006), Chung-Ang University Graduate Certificate in Learning and Teaching (2022), Advance HE His research focuses on quantum phenomena in biological systems at physiological temperatures, particularly using femtosecond optical spectroscopy and genetically engineered fluorescent proteins to explore evolutionary adaptations and develop quantum-bio-inspired technologies like room-temperature single-photon sources. The 15 most recent publications span quantum biology, biophotonics, and optical spectroscopy, with particular emphasis on quantum coherence in biological systems , terahertz birefringence , fluorescent protein dynamics , and biomedical imaging innovations . These works demonstrate his interdisciplinary approach bridging physics, biology, and medical applications. As QB-DTC Director, he leads transdisciplinary initiatives fostering collaboration between quantum physics and biosciences. His technical expertise includes time-correlated single-photon counting , common-path interferometry , and ultrafast fluorescence depolarization techniques.

Elaine O'Reillyمشاهده پروفایل

دانشیار

• Biocatalysis
• Organic Chemistry
• Enzyme Engineering
• +۳ مورد دیگر

Elaine O'Reilly is an Associate Professor and Vice-Principal for Research & Innovation at the School of Chemistry, University College Dublin . She holds a PhD in organic chemistry from UCD (2010) and has held academic positions at the University of Manchester (Postdoctoral 2010-2014), Manchester Metropolitan University (Lecturer 2014-2015), and University of Nottingham (Assistant Professor 2015-2019, promoted to Associate Professor 2018). Expertise in biocatalyst development and application Specialization in transaminase and cytochrome P450 engineering Focus on sustainable pharmaceutical and fine chemical synthesis Research Interests center on creating biocatalytic cascades for synthesizing complex molecules like chiral amines and iminosugars. She pioneered transaminase-triggered aza-Michael reactions for alkaloid synthesis and developed smart amine donors to overcome equilibrium limitations in biotransformations. Scientific Awards include the RSC Harrison-Meldola Prize (2017) Grants from EPSRC, BBSRC, and SFI support her work on continuous transaminase processes, heterogeneous biocatalysts, and sustainable chemistry collaborations with the University of Nottingham. Teaching Activities include coordinating the Aspects of MedChem and ChemBio module since 2019 and supervising PhD/BSc theses on biocatalysis and chemical biology.

Ramanujan Hegdeمشاهده پروفایل

استاد

• Cell Biology
• Molecular Biology
• Membrane Proteins
• +۳ مورد دیگر

Ramanujan Hegde serves as a Professor and Group Leader at the MRC Laboratory of Molecular Biology (LMB), University of Cambridge, where he directs research on membrane protein biosynthesis and cellular quality control mechanisms. His work examines how membrane proteins are accurately targeted to organelles, inserted into lipid bilayers, folded, and assembled into functional complexes, with emphasis on the cellular pathways that eliminate defective proteins to prevent disease. Professor Hegde's research program focuses on fundamental questions in cell biology: How do cells ensure precise membrane protein localization? What molecular machinery governs protein insertion and folding? How do quality control systems detect and degrade misfolded proteins? His investigations reveal that biosynthetic failures are common, triggering degradation pathways linked to diseases like neurodegeneration. Key research areas include: Intramembrane chaperone mechanisms for multipass membrane proteins Orphan subunit recognition during complex assembly Ribosome-associated mRNA degradation in autoregulation Proteasome assembly quality control ER membrane protein complex functions Molecular basis of protein aggregation diseases His 2017-2023 publications in Cell, Nature, and Science demonstrate consistent innovation in protein quality control, with landmark discoveries including UBE2O's role in orphan subunit degradation, the EMC as a transmembrane domain insertase, and TTC5-mediated tubulin autoregulation. These works bridge basic cell biology with disease mechanisms through rigorous biochemical and structural approaches. Professor Hegde mentors a research team of 11 scientists: Christine Desroches Altamirano Zhong Yan Gan Dino Janssen Ryan Judy Jennifer Miao Elizabeth Miller Tim Stevens Julia Toplak Huping Wang Haoxi Wu Eszter Zavodszky His laboratory operates within the MRC LMB's world-class infrastructure, utilizing advanced techniques in biochemistry, structural biology, and cell imaging. Supported by Medical Research Council funding, the group maintains strong collaborations across Cambridge and internationally to dissect protein biogenesis pathways with implications for therapeutic development in protein-misfolding disorders.