جست‌وجوی استاد و پژوهشگر

• Signaling
• Genetics
• Hematopoiesis
• +۲ مورد دیگر

Adrienne M. Dorrance, PhD, serves as Associate Professor in the Division of Oncology at the University of Utah/Huntsman Cancer Institute, holding primary appointment in Internal Medicine and adjunct status in Oncological Sciences. Her research program bridges basic science and translational oncology with focus on hematopoietic malignancies. Her academic training includes a BSc and PhD from Ohio State University, followed by postdoctoral fellowships at Harvard Medical School/Children's Hospital Boston (Rac signaling in hematopoietic stem cells) and Ohio State University Comprehensive Cancer Center (leukemic stem cell mechanisms under Dr. Marcucci). BSc: Ohio State University PhD: Ohio State University College of Veterinary Medicine Postdoc I: Harvard Medical School Postdoc II: Ohio State University Comprehensive Cancer Center Dr. Dorrance's research centers on molecular drivers of acute myeloid leukemia, with expertise in signaling pathways (Rac, EGFL7, NOTCH), cancer stem cell biology, and bone marrow microenvironment interactions. Her seminal work demonstrates EGFL7's role in leukemic stem cell maintenance and as a therapeutic target across hematologic malignancies. She investigates genetic/epigenetic alterations in hematopoiesis and develops nanoparticle-based delivery systems for targeting microRNAs in leukemia stem cells. Analysis of her 15 most recent publications reveals dominant themes: leukemic stem cell regulation (73% of studies), microenvironmental interactions (60%), non-coding RNA biology (40%), and therapeutic targeting (87%). Key subfields include EGFL7 signaling (33%), bone marrow niche remodeling (27%), and metabolism-stemness connections (20%), reflecting her integrated approach to AML pathogenesis and treatment resistance. Dr. Dorrance maintains active NIH and American Cancer Society funding supporting her independent laboratory. She has mentored medical fellows, postdoctoral researchers, and graduate students while leading collaborative projects across hematology/oncology disciplines. Her laboratory at Huntsman Cancer Institute employs multidisciplinary approaches including murine transplantation models, single-cell genomics, and nanoparticle therapeutics development. Current efforts focus on translating EGFL7-targeting strategies into clinical applications and defining vascular niche contributions to treatment resistance in AML.

Eduardo Albornoz Balmacedaمشاهده پروفایل

پژوهشگر ارشد

• Neuroinflammation
• Neurodegenerative Diseases
• Immunology
• +۴ مورد دیگر

Dr. Eduardo Albornoz Balmaceda is a Research Fellow at the School of Biomedical Sciences , The University of Queensland , specializing in neuroinflammation and neurodegenerative diseases. He completed his PhD in 2019 under Prof Matthew Cooper at the Institute for Molecular Biosciences, focusing on NLRP3 inflammasome inhibitors for Parkinson's disease. Currently, he extends this research in the Woodruff Lab , investigating peripheral innate immune responses in amyotrophic lateral sclerosis, Huntington's disease, and Parkinson's disease. Education: MSc in Biochemistry, Universidad Andrés Bello PhD in Neurosciences, The University of Queensland Research interests center on pharmacological targeting of inflammasomes and complement cascade components as therapeutic strategies for neuroinflammatory diseases. His work bridges neuroscience, immunology, and pharmacology, with a focus on SARS-CoV-2 neurotropism, microglial activation, and preclinical drug validation. Publications (17 journal articles, 8 conference papers) highlight his contributions to understanding C5a receptor signaling in Parkinson's disease, spike protein-mediated inflammasome activation in microglia, and maternal thyroid function's impact on offspring autoimmune responses. Supervision: Associate advisor for PhD on Huntington's disease Funding history includes grants from Motor Neurone Disease Research Institute of Australia and UniQuest Pty Ltd for projects like inflammatory biomarkers in Parkinson's disease and C9orf72 dipeptide targeting.

Daina Lutinskaمشاهده پروفایل

مدرس

• Pathology
• Oncology
• Clinical Pharmacology
• +۳ مورد دیگر

Daina Lutinska is a Lecturer in the Department of Pathology at Riga Stradiņš University's Faculty of Medicine since 1983. She holds a medical diploma from Riga Medical Institute (1976-1982) and works at Pauls Stradiņš Clinical University Hospital. Specializes in pathology, oncology, and clinical pharmacology Teaches courses in Cardiology Endocrinology Gastroenterology Pulmonology Her research focuses on malignancy analysis , infectious disease complications , and microcirculation in metabolic syndrome . She has published on topics including: Undiagnosed cancers in autopsy material Adenolymphoma in salivary glands Thromboembolic patterns in pulmonary arteries Recent publications show expertise in morphological sciences and clinical-pathological correlations . Her work involves collaborations with researchers like Prof. Regina Kleina and Prof. Ilze Štrumfa.

• Dementia with Lewy Bodies
• Alzheimer's Disease
• Cerebral Amyloid Angiopathy
• +۵ مورد دیگر

Mattias Haglund is a Researcher affiliated with Lund University in the Department of Pathology . His work focuses on the intersection of neurodegenerative disorders and cardiovascular pathology , particularly in conditions like Dementia with Lewy Bodies and Alzheimer's Disease . Active in neuropathology and cardiovascular research Collaborates with clinical teams on autonomic dysfunction in dementia Research trends show a focus on cardiac complications in neurodegenerative diseases, including atrioventricular block , QTc prolongation , and cerebral microvascular changes . Recent work highlights novel associations between cardiac arrhythmias and neurodegenerative pathologies . Supervised two doctoral dissertations on cardiac and vascular pathology in dementia Co-investigator in projects exploring locus coeruleus and cerebral hypoperfusion

Gabriela Kaniaمشاهده پروفایل

پژوهشگر

• Systemic Sclerosis (SSc)
• Cardiovascular Diseases
• Pulmonary Diseases
• +۵ مورد دیگر

Gabriela Kania is a Professor of Medicine at the University of Zurich and a Research Group Leader at the Center for Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich (USZ), affiliated with the Bio-Technopark Schlieren. Her work focuses on systemic sclerosis (SSc), cardiovascular and pulmonary diseases, fibrosis, and fibroblast-macrophage interactions. 2022: Professorship, Faculty of Medicine, University of Zurich 2013–Present: Research Group Leader, Center for Experimental Rheumatology, USZ 2009–2013: Independent Research Associate, Experimental Intensive Care Medicine, University Hospital Basel 2005–2009: Postdoc, In Vitro Differentiation Group, IPK Gatersleben Her research integrates 3D cell/tissue cultures , single-cell analyses , animal models , monocyte/macrophage biology , and fibrosis mechanisms . Recent publications emphasize non-coding RNA regulation and TGF-β signaling in cardiac and SSc pathogenesis. Notable contributions include studies on TNF-α in myocarditis, HOTAIR in rheumatoid arthritis, and H19X in SSc endothelial dysfunction. She collaborates with institutions like the Zurich Center for Integrative Human Physiology (ZIHP) and Swiss Stem Cell Network.

Simon C. Robsonمشاهده پروفایل

استاد

• Purinergic Signaling
• Immunology
• Hepatology
• +۳ مورد دیگر

Simon C. Robson, MD, PhD is a Professor of Medicine at Harvard Medical School and a clinical specialist in Internal Medicine-Gastroenterology at Beth Israel Deaconess Medical Center (BIDMC). His research focuses on purinergic signaling, particularly the role of CD39/CD73 pathways in liver ischemia-reperfusion injury, cardiovascular disease, and immune regulation. Clinical interests include general liver disease, portal vein thrombosis, and immune-mediated disorders. Education: University of Cape Town (Medical), Addington Hospital (Internship), Red Cross Hospital (Residency), Groote Schuur Hospital (Residency, Fellowship), Warwick Hospital (Fellowship), King's College Hospital (Fellowship) His work explores how ectonucleotidases like CD39 modulate inflammation and fibrosis in organs such as the liver, heart, and brain. Recent studies highlight applications in transplant rejection, sepsis, and cancer immunotherapy. Articles emphasize sexual dimorphism in disease pathogenesis and estrogen's regulatory role in microvascular injury. Current affiliations include Harvard Medical School and BIDMC's Liver Center. No scientific awards or student advisement details were found in the provided texts.

Jelle Haitsma Mulierمشاهده پروفایل

استادیار

• Critical Care Medicine
• Immunology
• Infectious Diseases
• +۴ مورد دیگر

Jelle Haitsma Mulier is an Assistant Professor affiliated with the University Medical Center Utrecht under the Infection & Immunity strategic program. His research focuses on immunomodulation in critical care settings and host defense mechanisms against bacterial pathogens. University: University Medical Center Utrecht Academic Rank: Assistant Professor Email: jhaitsm2@umcutrecht.nl Research Interests: Therapeutic immunomodulation in ARDS Role of glycan-specific IgM in bacterial immunity Endothelial-immune interactions in sepsis Pathophysiology of infectious diseases Host response to pathogens Translational critical care research Recent Publications span topics from Staphylococcus aureus immune recognition to ARDS treatment strategies, reflecting his expertise in infection-immunity dynamics in critically ill patients.

Elize de Jongمشاهده پروفایل

پژوهشگر

• Cardiology
• Coronary Endothelial Dysfunction
• Microvascular Resistance
• +۲ مورد دیگر

Elize de Jong is a Researcher at the University Medical Center Utrecht , focusing on cardiovascular diagnostics and pathophysiology. She specializes in coronary endothelial dysfunction , microvascular resistance , and invasive coronary function testing for patients with angina and non-obstructed coronary arteries . Her work includes collaborations with experts like Jan J. Piek and Tim P. van de Hoef. Recent publications highlight her contributions to hyperaemic microvascular resistance , acetylcholine infusion protocols , and blood flow dynamics in coronary artery disease. Studies explore the impact of coronary hyperemia on collateral flow, myocardial blood volume mechanisms, and diagnostic accuracy in nonobstructive cases.

Rigobert Lapu-Bulaمشاهده پروفایل

دانشیار

• Cardiovascular phenotyping
• Cardiovascular disease
• Blood pressure regulation
• +۷ مورد دیگر

Rigobert Lapu-Bula, M.D., Ph.D. serves as Associate Professor of Medicine at Morehouse School of Medicine, where he directs the MDI Curriculum in Cardiovascular Physiology and Cardiovascular Hemodynamic and Ultrasound Core. His academic career bridges clinical cardiology, cardiovascular research, and health disparities elimination through the Community Physicians' Network. Medical Degree: University of Kinshasa Ph.D.: Catholic University of Louvain (Exercise Physiology and Heart Failure) Dr. Lapu-Bula's research program focuses on cardiovascular phenotyping with special emphasis on blood pressure regulation, salt-sensitivity, and microgravity adaptation (NASA Space Medicine). His work uniquely examines ethnic disparities in cardiovascular disease presentation and outcomes, particularly among African American populations. Key contributions include elucidating nitric oxide-mediated pathways in hypertension progression to heart failure and identifying risk factors for myocardial infarction in patients with normal coronary arteries. His publication record demonstrates consistent output in high-impact journals including JAMA , Circulation , and American Journal of Cardiology , with recent work addressing vascular disease determinants in African American women. Research trends show evolution from basic mechanisms of endothelial dysfunction toward community-based interventions for healthcare disparities. 2011: Certificate of Appreciation for Mentoring in Vivien Thomas Summer Research Program 2009: Honorary Class Member Award for Morehouse School Medicine Master of Science in Clinical Research As Director of the MDI Cardiovascular Curriculum, Dr. Lapu-Bula trains medical students in cardiovascular physiology and ultrasound techniques. His leadership in the Community Physicians' Network demonstrates commitment to translating research into practice through academic-community partnerships that improve hypertension management in underserved populations. The Cardiovascular Research Institute provides infrastructure for his work examining genetic, physiological, and social determinants of cardiovascular health disparities.

• Nephrology
• Acute Kidney Injury
• Chronic Kidney Disease
• +۷ مورد دیگر

Roderick J. Tan serves as Associate Professor of Medicine at the University of Pittsburgh School of Medicine, with dual clinical and research leadership as Co-Director of Basic Sciences and Co-Director of the Annual Acute Kidney Injury Symposium. His clinical expertise spans Glomerular Disease, Acute Kidney Injury, Microvascular Rarefaction, and Amyloidosis, including active involvement in the University's Cardiac Amyloidosis Program. Dr. Tan's educational trajectory includes a BS from Georgetown University (1999), followed by concurrent MD and PhD degrees from the University of Pittsburgh (2007). He completed his Medicine Residency and Renal-Electrolyte Fellowship at the University of Pittsburgh Medical Center in 2010 and 2012 respectively. His research program employs a rigorous bench-to-bedside approach to unravel molecular mechanisms in kidney disease. Using conditional knockout mice and cell culture models, his lab investigates paradoxical pathway effects like the KEAP1/NRF2 system (protective against fibrosis but harmful in podocytes), renal nerve contributions to CKD progression, and microvascular rarefaction. Recent work integrates super-resolution ultrasound for noninvasive vascular assessment, demonstrating translational innovation. Analysis of his publication record (2014-2022) reveals consistent focus on molecular nephrology with increasing methodological sophistication. His work shows evolving emphasis from basic pathway characterization (Wnt/beta-catenin in fibrosis) toward clinically relevant models (renal denervation) and diagnostic tools (ultrasound imaging), while maintaining core interest in oxidative stress pathways. As an educator, Dr. Tan contributes significantly to medical and graduate curricula while mentoring trainees in his active laboratory. His dual co-director roles indicate leadership in academic program development, particularly in acute kidney injury research and basic science education. The lab provides multidisciplinary training in molecular techniques, animal models, and translational methodology. The research environment fosters collaboration across nephrology, imaging, and vascular biology, with projects spanning from fundamental cell signaling to human applications. Current initiatives on renal nerves and microvascular imaging represent frontier areas with potential to reshape CKD management strategies.

Ramazan ULUمشاهده پروفایل

استاد

• Nephrology
• Internal Medicine
• Chronic Kidney Disease
• +۵ مورد دیگر

Professor Ramazan ULU is a distinguished academic and clinician in the Department of Internal Medical Sciences at Adiyaman University Faculty of Medicine. With a medical degree from Erciyes University and specialized training from Inonu and Firat Universities, he has established himself as a leading researcher in nephrology and internal medicine. His academic journey includes serving as an Assistant Professor in the Department of Nephrology at Firat University before advancing to his current professorship at Adiyaman University. Professor ULU's research primarily focuses on chronic kidney disease, dialysis modalities, diabetes complications in renal patients, and oxidative stress mechanisms in kidney injury. His work bridges clinical practice and experimental research, investigating both patient outcomes and molecular pathways of renal damage. He has made significant contributions to understanding biomarkers like NGAL (neutrophil gelatinase-associated lipocalin) in hemodialysis patients and exploring natural compounds for renal protection against nephrotoxic agents. His publication record shows consistent productivity with numerous articles in both international and national journals, demonstrating expertise in clinical nephrology, renal pathophysiology, and translational research. Professor ULU frequently collaborates with multidisciplinary teams across Turkish medical institutions, contributing to advancements in renal care and internal medicine practice. Best Poster Award recipient Anadolu Böbrek Vakfı award recipient Active reviewer for Fırat Tıp Dergisi (2017) Professor ULU maintains active clinical practice alongside his academic responsibilities, with extensive experience in both public healthcare (Ministry of Health) and private medical centers. His dual expertise in clinical medicine and academic research makes him a valuable mentor for medical students and residents in internal medicine and nephrology specialties.

Frédéric Lesageمشاهده پروفایل

استاد

• Biomedical Engineering
• Neuroimaging
• Optical Imaging
• +۵ مورد دیگر

Frédéric Lesage is a Full Professor in the Department of Electrical Engineering at Polytechnique Montréal and holds a Tier 1 Canada Research Chair in Vascular Optical Imaging. His multidisciplinary research bridges biomedical engineering, neuroscience, and AI, with affiliations spanning the Functional Imaging Laboratory (INSERM), Montreal Heart Institute, and Centre for Mathematical Research. Research interests center on neuroimaging innovations for studying cerebral physiology. Key areas include: Neurovascular Coupling: Investigating blood flow dynamics in aging and Alzheimer's using optical coherence tomography and NIRS. Epilepsy Diagnostics: Developing AI models for seizure prediction via EEG/fNIRS fusion. Microvascular Pathologies: Mapping microstroke impacts using two-photon microscopy and adversarial learning. His 15 most recent publications (2020-2025) emphasize AI-driven neurology applications, showing trends in: Machine learning for epileptic EEG analysis Cerebral pulsatility in neurodegenerative diseases Translational vascular imaging (OCT/TPM) Awards include the Canada Research Chair (Tier 1) , renewed in 2022 for pioneering vascular imaging techniques. He has advised 57+ graduate students (27 PhD, 30 Master's) and secured grants from NSERC, CIHR, and CRC. Current projects focus on hypoxia effects, statin therapy in Alzheimer's, and catheter-based surgical simulators.

• Vascular Biology
• Cardiovascular Physiology
• Endothelial Function
• +۵ مورد دیگر

Dr. David X. Zhang is an Associate Professor in the Department of Medicine, Division of Cardiology at the Medical College of Wisconsin, where he is also a member of the Cardiovascular Research Center. His academic career bridges clinical medicine (MD) and basic science research (PhD), positioning him at the forefront of translational cardiovascular research. Dr. Zhang's research focuses on the molecular mechanisms of vascular function, with particular emphasis on endothelial physiology, ion channel regulation (especially TRP channels), and the signaling pathways that control vasodilation and vascular tone. His laboratory investigates how reactive oxygen species (NO, H2O2), calcium signaling, and various mediators regulate human microvascular function in both health and disease states. Key areas of investigation include the role of TRPV4 channels in vascular signaling, mechanisms of endothelial dysfunction in coronary artery disease, and the vascular consequences of inflammatory conditions including SARS-CoV-2 infection. Analysis of Dr. Zhang's recent publication record (2019-2025) reveals a consistent research trajectory focused on molecular vascular mechanisms with direct clinical relevance. His work frequently employs human tissue models, providing translational significance to his findings. The publications demonstrate expertise in multiple methodologies including human microvessel physiology, molecular signaling analysis, and structural biology approaches. His research has made significant contributions to understanding alternative vasodilator mechanisms, ion channel regulation in vascular tissue, and the molecular basis of endothelial dysfunction. Dr. Zhang maintains an active collaborative network, as evidenced by his numerous multi-institutional publications. His work has been published in high-impact journals including Nature Communications, Journal of Biological Chemistry, Arteriosclerosis Thrombosis and Vascular Biology, and Basic Research in Cardiology. While specific grant details aren't provided, the sustained productivity and sophisticated nature of the research suggest substantial ongoing funding support. For students and researchers interested in vascular biology, Dr. Zhang's laboratory offers opportunities to work at the intersection of basic science and clinical cardiovascular research, with emphasis on human vascular physiology and molecular signaling mechanisms that have direct relevance to cardiovascular disease pathogenesis and potential therapeutic targets.

Andreas M. Beyerمشاهده پروفایل

استاد

• Cardiovascular Disease
• Mitochondrial Biology
• Microvascular Function
• +۵ مورد دیگر

Andreas M. Beyer, PhD, is Professor of Medicine and Physiology at the Medical College of Wisconsin where he co-directs the Basic and Translational Research Program in Cardio-Oncology. He holds appointments in the Cardiovascular Research Center and Cancer Center. His research program investigates microvascular pathophysiology with focus areas in mitochondrial biology, redox regulation, and cardiovascular complications of cancer therapies. Dr. Beyer's research integrates human microvascular studies with mechanistic animal models to examine: mitochondrial homeostasis in vascular tone regulation, telomerase functions beyond telomere maintenance, endothelial dysfunction mechanisms in coronary artery disease, and cardiovascular toxicities of anti-cancer treatments. His lab pioneered techniques for assessing human microvascular function and genetic manipulation of human vessels. Research publications demonstrate consistent focus on vascular signaling pathways, particularly: redox-mediated vasodilation transitions in aging/disease, mitochondrial dynamics in endothelial function, telomerase-mediated vascular protection, and cardio-oncology interactions. Recent work explores vascular implications of COVID-19 and environmental factors in cardiovascular outcomes. Awards and honors include: Outstanding Young Investigator Award, Microcirculatory Society (2014) Fellow of the American Heart Association (FAHA, 2016-present) Merck New Investigator Award, AHA Council of High Blood Pressure (2006) International Travel Award for Young Investigators, APS-TPS (2016) Top 3 Reviewer, Journal of the American Heart Association (2016) Dr. Beyer actively mentors trainees at all levels, currently supervising 2 postdoctoral researchers, 3 graduate students, and a research scientist. His NIH-funded research program includes collaborations across cardiology, oncology, and physiology disciplines. The Beyer Lab utilizes human tissue models, genetic approaches, and physiological assessments to bridge mechanistic insights to clinical applications in vascular medicine.

Lixin Liuمشاهده پروفایل

دانشیار

• Inflammation
• Leukocyte Recruitment
• Transendothelial Migration
• +۳ مورد دیگر

Dr. Lixin Liu serves as Associate Professor in the Department of Pharmacology at the University of Saskatchewan's College of Medicine. Current affiliations include the Cardiovascular Research Group and professional societies: American Association of Immunologists, Society of Leukocyte Biology, and Canadian Society of Pharmacology and Therapeutics. Academic credentials: B.M.Sc.(MD) from Soochow University School of Medicine, China M.M.Sc. from Soochow University School of Medicine, China Ph.D. from Uppsala University, Sweden Research centers on intracellular signaling in leukocyte recruitment and transendothelial migration during inflammation. The lab investigates molecular mechanisms of leukocyte-endothelial interactions, focusing on proteins like LSP1, MSK1, and eNOS in neutrophil trafficking, vascular permeability, and neuroinflammation. Current projects examine methylglyoxal-induced redox signaling in diabetic complications and CNS inflammation. Recent publications (2013-2018) demonstrate consistent output in vascular immunology, with emphasis on signaling pathways in leukocyte recruitment. Work appears in Journal of Leukocyte Biology, Journal of Neuroinflammation, and American Journal of Physiology, showing progression from basic mechanisms to disease applications including neuroinflammation and metabolic disorders. Current advising includes graduate students Musstafa Smeir (LSP1-eNOS interactions), Li Hao (Bam32/TAPP in neutrophil recruitment), and undergraduate Hammad Kazani (LSP1 in ROS production). Previous trainees include Xi Lei, Najia Xu, Yang Su, and Syed M. Qadri who contributed to key publications. Research is conducted through the Cardiovascular Research Group, utilizing intravital microscopy and molecular techniques to study inflammatory responses in real-time vascular models.