جستجوی استاد راهنمای دانشگاهی

Katherine J. Franz is a Professor of Chemistry at Duke University, affiliated with the Trinity College of Arts & Sciences and the Duke Cancer Institute. She holds a Ph.D. from MIT (2000) and a B.A. from Wellesley College (1995). Her research focuses on bioinorganic chemistry, particularly metal ion coordination in biological systems, with applications in antimicrobial therapies, cancer metallomics, and neurodegenerative diseases. Key projects include developing prochelators targeting fungal and bacterial pathogens, studying copper's role in antifungal drug efficacy, and designing light-activated metal complexes for controlled drug release. Dr. Franz has received numerous awards including the Camille Dreyfus Teacher-Scholar Award (2009), Sloan Research Fellowship (2008), and the NSF CAREER Award (2005). She leads a lab with 6 current students/mentees and has secured grants from NIH, NSF, and the US-Israel Binational Science Foundation. Her lab's work spans from fundamental metalloprotein studies to translational drug development, emphasizing interdisciplinary approaches in chemistry and biology. Education: Ph.D. in Chemistry, MIT, 2000 B.A. in Chemistry, Wellesley College, 1995 Research Interests: Metal homeostasis in pathogens, copper's role in antifungal resistance, prodrug design for targeted therapy, and mechanistic studies of metalloproteins. Grants: Tri-Institutional Molecular Mycology Training Program (NIH, 2024–2029) Duke PREP Biomedical Sciences Program (NIGMS, 2022–2027) Copper-Mucin Interaction Study (BSF, 2022–2026) Her lab's publications (n=15+ since 2020) highlight breakthroughs in prodrug selectivity, copper-induced protein toxicity, and histatin antifungal mechanisms. The Franz Lab actively collaborates with clinicians and computational scientists to advance therapeutic strategies addressing unmet medical needs in infectious diseases and cancer.

• Bioinorganic Chemistry
• Metal Homeostasis
• Antimicrobial Agents
• +۴ مورد دیگر

Parisa Hosseinzadeh is an Assistant Professor in the Department of Bioengineering at the University of Oregon. Her research focuses on computational protein design and structure-guided rational protein/peptide engineering, with applications in enzyme design, biosensors, and biomedical solutions. She holds a B.Sc. from the University of Tehran, a Ph.D. from the University of Illinois (advisor: Yi Lu), and a postdoc at the University of Washington in David Baker's lab. Her lab emphasizes interdisciplinary approaches at the intersection of computer science, chemistry, and biology, prioritizing diversity and inclusion in STEM. Key projects include designing cyclic peptides as enzyme inhibitors, developing methods for tuning redox potentials in metalloproteins, and creating tools to combat biomedical challenges. Lab members include postdocs, graduate students (e.g., Noora Azadvari, Andrew Powers), and undergraduates. Notable achievements include NSF grants, the Baxter Foundation Award, and the Hans Horse Meyer Award. The lab also emphasizes mentorship, collaborative culture, and outreach initiatives.

• Protein Design
• Computational Biochemistry
• Biosensors
• +۳ مورد دیگر

Uwe Bergmann is the Martin L. Perl Endowed Professor in Ultrafast X-Ray Science at the University of Wisconsin-Madison's Department of Physics. His research leverages advanced X-ray techniques to study nonlinear phenomena, real-time chemical reactions, and structural changes in both biological and material systems, with a focus on photosynthesis and ancient cultural heritage. PhD in Physics from Stony Brook University Former affiliations: National Synchrotron Light Source, European Synchrotron Radiation Facility, Lawrence Berkeley National Laboratory, Stanford Synchrotron Radiation Lightsource, Linac Coherent Light Source, Stanford PULSE Institute His work spans ultrafast X-ray spectroscopy, synchrotron methods, and the development of novel instruments like the X-FAST tabletop spectrometer. Research themes include: Photosynthetic water oxidation mechanisms using femtosecond X-ray crystallography Electronic and structural dynamics in 2D materials and metalloenzymes Imaging ancient fossils and manuscripts with X-ray techniques Advancing X-ray laser and synchrotron instrumentation Recent publications highlight attosecond X-ray pulses, catalysis under extreme conditions, and structural intermediates in photosystem II. His work intersects physics, chemistry, and paleobiology. Scientific recognition includes the Martin L. Perl Endowed Professorship. He leads the Bergmann Research Group, mentoring graduate students and postdocs in ultrafast X-ray science.

• Ultrafast X-ray Science
• Synchrotron Radiation
• X-ray Free-Electron Lasers
• +۵ مورد دیگر

Jun.-Prof. Dr. Franziska Thomas is a Junior Professor at the Institute of Organic Chemistry, Heidelberg University, leading an active research group at the interface of organic chemistry, biochemistry, and biophysics. Her work centers on understanding protein folding mechanisms and their implications for biological function. Dr. Thomas established her independent research group at Georg-August-Universität Göttingen in June 2015 before moving to Heidelberg University in February 2020. She was offered her current tenure track position at Heidelberg on April 26, 2019. Her research program has two primary focuses: (1) designing peptide scaffolds with catalytic activity using de novo designed components that can be chemically synthesized and modified, and (2) studying protein aggregation mechanisms relevant to neurodegenerative diseases such as amyotrophic lateral sclerosis. She employs small, well-characterized self-assembling peptides to create novel materials and understand disease pathways. Analysis of her publication record reveals consistent advancement in peptide and protein engineering, with recent work emphasizing WW domains, β-sheet miniproteins, and innovative solid-phase synthesis techniques. Her research bridges fundamental protein science with applications in materials engineering and disease mechanism understanding. Her work has received significant funding including: The excellence cluster 3DMM2O for the project 'Design of Structured Adhesion Miniproteins for Tissue Engineering' The Deutsche Forschungsgemeinschaft for the research grant 'The WW-domain scaffold as a model system for the de novo design of miniaturized phosphate receptors, phosphatases and sulfatases' Dr. Thomas actively mentors a large research team including 11 PhD students and 2 Master's students, with numerous past students who have successfully completed their theses. She teaches courses including 'Chemische Biologie' and 'OC-Z6 Synthese und Retrosynthese' and participates in seminar series such as IMSEAM and 3DMM2O. The Thomas Lab maintains strong collaborative connections with multiple research groups including the Kivala, Kemerink, Blasco, Klein, Comba, and Gräter groups, reflecting an interdisciplinary approach to peptide and protein science.

• Protein Folding
• Peptide Design
• Protein Aggregation Mechanisms
• +۶ مورد دیگر

Professor Tobin J. Marks is the Vladimir N. Ipatieff Professor of Catalytic Chemistry, Professor of Materials Science and Engineering, Professor of Applied Physics, and Professor of Chemical and Biological Engineering at Northwestern University. He also serves as a Distinguished Adjunct Professor at Texas A&M Qatar University and is a Senior Fellow of the Hong Kong Institute for Advanced Study at City University of Hong Kong. Dr. Marks is a member of the US National Academy of Engineering, the US National Academy of Sciences, and a Fellow of the Royal Society of Chemistry, UK. Dr. Marks received his BSc in Chemistry from the University of Maryland in 1966 and his PhD in Inorganic Chemistry from MIT in 1970. His academic career at Northwestern began as an Assistant Professor of Chemistry in 1970, progressing to Associate Professor in 1974, Professor of Chemistry in 1978, Charles E. & Emma H. Morrison Professor of Chemistry from 1986-1999, Vladimir N. Ipatieff Professor of Catalytic Chemistry since 1999, Professor of Materials Science and Engineering since 1987, Professor of Applied Physics since 2009, and Professor of Chemical and Biological Engineering since 2017. Professor Marks' research spans numerous areas of chemistry and materials science. His work focuses on transition metal and f element organometallic chemistry, catalysis, vibrational spectroscopy, synthetic facsimiles of metalloprotein active sites, carcinostatic metal complexes, solid state chemistry and low-dimensional molecular metals, nonlinear optical materials, polymer chemistry, tetrahydroborate coordination chemistry, macrocycle coordination chemistry, molecular electro-optics, metal-organic chemical vapor deposition, polymerization catalysis, printed flexible electronics, solar energy, and transparent conductors. His research group consists of nearly 40 researchers working across four laboratories. Analysis of Professor Marks' recent publications reveals a strong focus on advanced materials for electronic and energy applications. His work spans organic electronics, flexible and stretchable devices, catalysis for sustainable chemistry, and novel materials characterization techniques. Key trends include the development of organic electrochemical transistors, high-efficiency organic solar cells, advanced catalysts for polymer recycling, and quantum materials for next-generation electronics. Professor Marks has received numerous prestigious awards throughout his career, including: US National Medal of Science American Chemical Society Joseph Priestley Medal Camille and Henry Dreyfus Prize in the Chemical Sciences Principe de Asturias Prize for Technical and Scientific Research US National Academy of Sciences Award in the Chemical Sciences Materials Research Society Von Hippel Award Harvey Prize in Science and Technology Karl Ziegler Prize from the German Chemical Society Professor Marks has mentored numerous students and postdoctoral researchers throughout his career, with his group currently consisting of nearly 40 researchers. He has received substantial research funding from multiple agencies including NSF, DOE, and DoD. His entrepreneurial spirit has led to the founding or co-founding of 15 startups, with technologies generating an estimated USD 100 billion in sales. Professor Marks leads several research teams focused on catalysis and organic electronic materials. His work has significant implications for sustainable chemistry, renewable energy, and next-generation electronic devices. He continues to be highly active in research, with numerous publications in 2025 demonstrating his ongoing scientific leadership.

• Transition Metal Organometallic Chemistry
• f Element Organometallic Chemistry
• Catalysis
• +۱۵ مورد دیگر

Giacomo Parigi is an Associate Professor of Chemistry at the University of Florence, affiliated with the Magnetic Resonance Center and the Department of Chemistry. His work focuses on paramagnetic effects in NMR, MRI contrast agents, and protein dynamics. He holds a Physics degree (1992) and a Chemistry PhD from the University of Florence, with postdoctoral and research roles at CERM since 1999. Research Interests: Parigi’s research explores paramagnetic effects in biological molecules, including protein structure determination, MRI contrast agent design, and relaxometry. He co-authored seminal books on NMR of paramagnetic molecules and pioneered methods for studying protein dynamics via field-cycling NMR. His lab integrates computational biology, bioinformatics, and experimental NMR to address biomedical challenges. Publications & Trends: Recent work emphasizes machine learning-enhanced NMR analysis, novel MRI probes (e.g., Mn-based nanogels), and structural studies of metalloproteins. His articles highlight innovations in paramagnetic NMR restraints, dynamic aggregation imaging, and low-field MRI applications. Awards & Grants: No explicit awards mentioned, but his extensive publications reflect significant contributions to NMR methodology. Active in securing grants for structural biology and biomedical imaging projects. Labs & Teams: Leads the Magnetic Resonance Center’s NMR group, collaborating on interdisciplinary projects involving biomaterials, drug design, and protein engineering. His team develops cutting-edge tools for in-cell NMR and metabolomics analysis.

• Nuclear Magnetic Resonance (NMR)
• Paramagnetism-Based Effects
• MRI Contrast Agents
• +۴ مورد دیگر

Professor Peter Z. Qin is a faculty member in the Department of Chemistry at the University of Southern California (USC), affiliated with the USC Dornsife College of Letters, Arts and Sciences. His research focuses on understanding nucleic acid recognition mechanisms, genome engineering, and CRISPR-Cas systems, employing advanced techniques like Site-Directed Spin Labeling (SDSL) and electron paramagnetic resonance (EPR) spectroscopy. Qin earned his Ph.D. from Columbia University (1999) and B.S. from Peking University (1991). Research interests include structural dynamics of nucleic acids, protein-nucleic acid interactions, and CRISPR-mediated DNA cleavage mechanisms. His work bridges physical chemistry and biochemistry, with applications in diagnostics, therapeutics, and gene editing. Notable contributions involve elucidating CRISPR-Cas9 and Cas12a mechanisms, DNA-unwinding checkpoints, and the role of bridge helices in target discrimination. Recent publications (2021–2025) emphasize CRISPR-Cas systems, DNA dynamics, EPR-based instrumentation, and molecular mechanisms of genome editing. His group develops tools like dual-mode EPR spectrometers and phosphorothioate-based RNA labeling techniques. The lab actively publishes in high-impact journals and collaborates on translational projects like CRISPR-engineered mouse models. Prof. Qin’s work is supported by grants and collaborations, though specific funding details are not listed. His lab maintains a dedicated website detailing ongoing research and methodologies.

• Physical Chemistry
• Biochemistry
• CRISPR Technology
• +۳ مورد دیگر

Alessandra Pesce is an Associate Professor at the Department of Physics (DIFI) of the University of Genoa, Italy. Her research focuses on structural biology of globins, protein aggregation, and cold-adapted enzymes, with applications in life sciences, environmental monitoring, and cultural heritage preservation. She teaches Applied Physics and Biophysics at both undergraduate and graduate levels in Physics and Biological Sciences. Her work spans from atomic-level characterization of protein crystals using Atomic Force Microscopy to large-scale ecological projects like the LIFE+ WHALESAFE initiative for sperm whale conservation through acoustic monitoring. Email: alessandra.pesce@unige.it Phone: +39 010 33 56243 Research Interests: Structural characterization of hexa-coordinated globins in marine organisms Thermodynamic and kinetic analysis of truncated hemoglobins in pathogenic bacteria Quaternary structure adaptations in Antarctic enzymes Development of acoustic monitoring systems for marine mammal conservation Protein aggregation mechanisms in amyloid-related diseases Publication Trends: Over 15 years, her research demonstrates expertise in combining X-ray crystallography with biophysical techniques to study globin family proteins across diverse species (from nematodes to whales). Key themes include heme reactivity modulation, ligand diffusion pathways, and structure-function relationships in extremophile proteins, with recent emphasis on marine conservation technology.

• Biochemistry
• Structural Biology
• Molecular Biophysics
• +۴ مورد دیگر

Dr. Lars Lauterbach is a University Professor at RWTH Aachen University , leading the Department of Synthetic Microbiology . His research focuses on molecular genetics, biochemistry, and gas-converting biocatalysts, particularly hydrogen-dependent enzymatic processes. Institution: RWTH Aachen University Role: Institute Head Contact: lars.lauterbach@rwth-aachen.de His work spans hydrogen metabolism , metalloenzymes , and electrobiochemistry , with recent publications emphasizing CO2 conversion, hydrogenase engineering, and enzymatic cofactor regeneration. Key research areas include: Hydrogen-driven biocatalytic cascades Oxygen-tolerant hydrogenases Carbon dioxide valorization Multi-step enzymatic synthesis Hydrogen storage and utilization Redox chemistry in metalloproteins The 2023-2025 article list reflects trends in CO2-based biotechnology , biocatalytic hydrogenation , and synthetic microbial systems , with applications in pharmaceuticals, fine chemicals, and sustainable energy.

• Molecular Genetics
• Biochemistry
• Biocatalysis
• +۶ مورد دیگر

Mark F Reynolds is an Associate Professor at the Department of Chemistry and Biochemistry, Saint Joseph’s University. He earned a BA in Chemistry from Grinnell College (1993) and a PhD in Inorganic Chemistry from the University of Wisconsin-Madison (1999), followed by postdoctoral work at the University of Minnesota. His research focuses on heme-based gas sensing proteins that regulate biological processes like blood pressure and nitrogen fixation. He pioneered studies on the oxygen-sensing FixL protein in alfalfa and soybean agriculture and discovered the heme-responsive ion channel in human Slo1 BK channels. Collaborations with Dr. Toshi Hoshi’s lab at the University of Pennsylvania advanced understanding of heme signaling. Recent publications highlight bioremediation of industrial dyes via heme protein catalysis (2024), conformational dynamics in FixL oxygen sensing (2024), and structural analysis of Mn(II) enzyme active sites (2005). Scientific awards include the 2022 ACS Excellence in College Teaching Award . He has directed the Office of Fellowships at Saint Joseph’s University, mentoring students to secure Fulbright , Goldwater , and NSF fellowships. His outreach includes urban nutrition education projects and media appearances on NPR and in Science Daily .

• Inorganic Biochemistry
• Heme-Based Gas Sensing Proteins
• Bioremediation
• +۳ مورد دیگر

David R Cooper serves as an Assistant Professor of Research in the Department of Molecular Physiology and Biological Physics at the University of Virginia School of Medicine. His work focuses on developing data management systems for structural biology research, particularly in the field of X-ray crystallography. Dr. Cooper earned his BS in Biochemistry from Old Dominion University followed by a PhD in Biochemistry and Molecular Biology from Purdue University. His educational background provides the foundation for his current research in structural biology data systems. His primary research interest centers on data management and analysis for scientific endeavors, with specialization in X-ray crystallography. Dr. Cooper is currently developing a next-generation Laboratory Information Management System (LIMS) designed to track experimental procedures and parameters throughout the entire structural biology pipeline - from initial cloning to final structure deposition in the Protein Data Bank. His work addresses critical challenges in scientific reproducibility by ensuring protocols, data, and necessary metadata are properly documented and accessible. Analysis of Dr. Cooper's publication history reveals consistent contributions to structural biology data management, with particular emphasis on database development, validation tools, and visualization systems. His research spans bioinformatics, structural biology, and data science, with applications in macromolecular characterization and scientific reproducibility frameworks. Dr. Cooper maintains active research collaborations within the structural biology community, particularly with Dr. Wladek Minor's research group as indicated by his website (https://minorlab.org/person/dcoop/). His work supports the broader structural biology research enterprise through development of essential data infrastructure tools. His laboratory focuses on creating flexible systems capable of managing experimental samples and workflows for all stages of structural biology research. The LIMS development project represents a significant contribution to standardizing and improving data management practices in macromolecular structural analysis.

• X-ray crystallography
• Data management
• Structural biology
• +۳ مورد دیگر

Dr. Olaf Rüdiger is a Group Leader at the Max Planck Institute for Chemical Energy Conversion (MPI CEC), leading the Spectroelectrochemistry group within the Department of Inorganic Spectroscopy. His research focuses on understanding and designing bio-inspired catalysts for hydrogen production/oxidation and energy conversion systems, particularly using hydrogenases and earth-abundant metal complexes. He earned his B.Sc. from the University of Valencia (2003), M.Sc. from Universidad Autónoma de Madrid (2006), and Ph.D. from Universidad Autónoma de Madrid and CSIC (2009). His work combines electrochemistry with advanced spectroscopic techniques to study catalyst dynamics under operational conditions. Key research areas include: Development of redox hydrogels to protect oxygen-sensitive hydrogenases Electrochemical and spectroscopic analysis of OER catalysts (e.g., cobalt oxides) Immobilization strategies for bio-inspired and enzymatic catalysts on electrodes His group has pioneered methods to stabilize hydrogenases in harsh environments using redox polymers, enabling their application in fuel cells. Recent studies emphasize operando characterization of catalysts during turnover, revealing insights into active site structures and reaction mechanisms. Laboratory collaborations include partnerships with Ruhr University Bochum (W. Schuhmann, N. Plumeré) and the Savitsky/Cox groups for in situ EPR/XAS studies. Current projects explore single-atom catalysts for water oxidation and light-responsive spin-state switches in iron complexes.

• Electrochemistry
• Catalysis
• Bio-inspired Materials
• +۵ مورد دیگر

Ivana Drienovska is an Assistant Professor in the Department of Chemistry and Pharmaceutical Sciences at the Faculty of Science, Vrije Universiteit Amsterdam . She also holds an affiliation with AIMMS (likely a research institute or program). Her research focuses on biocatalysis, protein engineering, and artificial enzyme design , with a particular emphasis on non-canonical amino acids, genetic code expansion, and functional group diversity in enzymes. She explores applications in sustainable chemistry, enzyme stabilization, and novel catalytic mechanisms. Recent work includes designing protein scaffolds for iminium biocatalysis, stabilizing protein complexes via covalent bicyclization, and incorporating functional secondary amines via genetic code expansion. Her studies often involve structural biology approaches (e.g., crystallography) and synthetic biology techniques. Affiliations : Faculty of Science (VU Amsterdam), AIMMS Courses Taught : Biocatalysis for a Sustainable Future, Bioorganic Chemistry, Concepts in Chemical Biology Key Research Themes : Engineering enzymes for novel functionalities (e.g., unnatural amino acids) Development of artificial metalloenzymes for asymmetric catalysis Structural and biochemical analysis of cold-adapted and extremophilic enzymes Lab/Team : Her group works at the interface of chemical biology, enzymology, and synthetic biology, focusing on creating next-generation biocatalysts for industrial and environmental applications.

• Biocatalysis
• Protein Engineering
• Non-Canonical Amino Acids
• +۵ مورد دیگر

Claudia Andreini is an Associate Professor at the University of Florence, affiliated with the Magnetic Resonance Center and the Department of Chemistry. Her research focuses on computational biology, particularly metalloproteins and bioinformatics. She pioneered the use of bioinformatics to study metalloproteins and developed the MetalPDB database. She collaborates internationally and has presented at major conferences. Education: PhD in Chemistry (2006), University of Florence; Laurea in Chemistry (2002, cum laude), University of Florence. Research interests include metalloprotein structure-function relationships, metal-coordination databases, and predictive computational tools. Her work integrates structural bioinformatics, machine learning, and database mining to analyze metal sites in proteins. Recent publications highlight advancements in zinc-binding site prediction, metal-induced structural variability, and applications of deep learning in metalloprotein analysis. She has contributed to drug design studies involving ruthenium complexes and antibacterial agents. No scientific awards or grants are explicitly listed in the provided texts. She leads the MetalPDB project and collaborates on structural biology initiatives.

• Metalloproteins
• Bioinformatics
• Biological Databases
• +۳ مورد دیگر

Miguel A. De la Rosa is a Full Professor of Biochemistry and Molecular Biology at the University of Seville since 1995. His academic career spans leadership roles including Director of cicCartuja Scientific Research Center (2009-18) and Secretary General of FEBS (2023-). He also served as Visiting Professor at the University of Arizona (1990-94). Education : M.Sc. (1st class honours, 1977) and Ph.D. (cum laude, 1981) in Biochemistry from the University of Seville. Research interests focus on structure-activity relationships of biological macromolecules, particularly protein-protein and protein-nucleic acid interactions. His work employs interdisciplinary approaches from molecular biology to computational chemistry, with major achievements in metalloprotein evolution, electron transfer mechanisms in photosynthesis/respiration, and cytochrome c's role in DNA damage and programmed cell death. Publication trends emphasize cytochrome c modifications (phosphorylation, acetylation), electron transfer dynamics, structural analysis of redox proteins, and mitochondrial dysfunction. His studies bridge structural biology, biophysics, and molecular mechanisms of cell death. 2025 FAMA Prize for scientific career 2019 Honorary Member of SEBBM 2019 Elected Member of Academia Europaea FEBS National Lecture Award (2010) He has supervised more than 20 PhD students and 20 postdocs, co-founded spin-off ManSciTech S.L. , and directed large-scale interdisciplinary projects at CSIC-University of Seville institutes.

• Structural biology
• Biophysics
• Bioinorganic chemistry
• +۲ مورد دیگر