- Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS)
- Diagnostic Endocrinology
- Vitamin D Testing and Analysis
- +۴ مورد دیگر
Ravinder J. Singh, Ph.D. is a Professor of Laboratory Medicine and Pathology at Mayo Clinic, serving as Director of the Mayo Clinic Endocrine Laboratory with dual appointments in the Department of Laboratory Medicine and Pathology and the Division of Endocrinology within the Department of Internal Medicine. His work bridges clinical laboratory science and endocrinology through the development and implementation of advanced analytical methods for hormone measurement. Dr. Singh's educational background includes: PhD from Guru Nanak Dev University MS from Guru Nanak Dev University Bachelor of Education from Guru Nanak Dev University BS from Panjab University Postdoctoral Fellowship in Biochemistry from Medical College of Wisconsin Residency in Clinical Chemistry from Mayo School of Graduate Medical Education Dr. Singh's research program centers on applying liquid chromatography-tandem mass spectrometry (LC-MS/MS) to clinical laboratory analysis. He has pioneered numerous reference methods now widely adopted in clinical practice, with particular expertise in measuring cortisol, synthetic corticosteroids, metanephrines, estradiol, vitamin D, and urine albumin. The Endocrine Laboratory under his direction performs over 3,500 vitamin D tests daily using online extraction and LC-MS/MS methods. His work has directly improved diagnostic methods for Cushing's disease, pheochromocytoma, and congenital adrenal hyperplasia through conversion of various diagnostic endocrinology assays to gold standard LC-MS/MS reference methods. Analysis of Dr. Singh's extensive publication record reveals consistent focus on advancing clinical laboratory methods, particularly in endocrinology and mass spectrometry applications. His work spans analytical chemistry methodology development, clinical applications of novel testing approaches, and studies of hormone metabolism, with significant contributions to vitamin D metabolism and testing. Dr. Singh has received numerous prestigious awards throughout his career: Clinical Chemist Recognition Award from The American Association For Clinical Chemistry (2017) Leadership Award from The Association for Mass Spectrometry Applications to the Clinical Lab (2013) Clinical Chemist Recognition Award from American Academy of Forensic Sciences (2012) Multiple Clinical Chemist Recognition Awards from Association for Diagnostics & Laboratory Medicine Travel and Henry Christian Award from American Federation for Medical Research (2000) Van Slyke Society and Marshall Award from Association for Diagnostics & Laboratory Medicine (1999) As Director of the Mayo Clinic Endocrine Laboratory, Dr. Singh has served as Co-primary investigator on one industry-funded and two NIH-funded grants. He previously directed the Clinical Chemistry Postdoctoral Fellowship at Mayo Clinic and has held leadership positions including Former chair of the Midwest section of the American Association for Clinical Chemistry (AACC) and Treasurer of the proteomics division of AACC. Dr. Singh is certified in Clinical Chemistry by the American Board of Clinical Chemistry (2004). Dr. Singh leads the Mayo Clinic Endocrine Laboratory, which has been instrumental in converting various steroid, biogenic amine, and peptide hormone immunoassays to gold standard LC-MS/MS reference methods. His team's work on vitamin D testing has set new standards in the field, with significant implications for diagnosing and managing vitamin D deficiency. He maintains clinical appointments at Mayo Clinic locations in both Rochester, Minnesota and Jacksonville, Florida.









