جستجوی استاد راهنمای دانشگاهی

Ting Duمشاهده پروفایل

استادیار

• Neuroscience
• Neurology
• Brain Fluid Homeostasis
• +۷ مورد دیگر

Ting Du, M.D., Ph.D., is an Assistant Professor in the Department of Neurology at the University of Rochester Medical Center's School of Medicine and Dentistry. She leads the Du Lab, focusing on brain fluid homeostasis and its role in neurological diseases. Faculty: Assistant Professor, Department of Neurology Institution: University of Rochester Medical Center Lab: Du Lab Collaborations: Nedergaard Lab, Center for Translational Neuromedicine Research Interests: The Du Lab investigates cerebrospinal fluid (CSF) dynamics, glymphatic system function, and cervical lymphatic vessels in Alzheimer's disease, hydrocephalus, and traumatic brain injury. Key projects include: Restoring cervical lymphatic function to improve CSF drainage in aging Characterizing the subarachnoid lymphatic-like membrane (SLYM) in trauma Probing choroid plexus regulation in hydrocephalus Publication Trends: Recent work spans Neuroscience , Neurodegeneration , and Biophysics , with emphasis on: Glymphatic dysfunction in Alzheimer's Arterial pulsation-driven CSF flow Aquaporin-4's role in interstitial fluid Machine learning-based flow quantification Lab Affiliations: The Du Lab is part of the Neuroscience Ph.D. Program and Pathology - Cell Biology of Disease program, collaborating with experts in neuroimaging , fluid dynamics , and neurotherapeutics .

Greg Adamsonمشاهده پروفایل

استادیار بالینی

• Pediatric Cardiology
• Interventional Cardiology
• Pulmonary Arterial Hypertension
• +۳ مورد دیگر

Greg Adamson is a Clinical Assistant Professor in the Department of Pediatrics - Cardiology at Stanford University School of Medicine and a member of the Maternal & Child Health Research Institute (MCHRI) . He specializes in Interventional Cardiology and Lymphatic Diseases , with clinical expertise in managing conditions like chylothorax and pulmonary arterial hypertension. Medical Education : St. Louis University School of Medicine (2014) Residency : University of California San Francisco (2017) Fellowship : Stanford University Pediatric Cardiology Fellowship (2020) Board Certifications : Pediatrics (2017) and Pediatric Cardiology (2024) Dr. Adamson's research focuses on pediatric pulmonary hypertension , cardiac catheterization protocols , and postoperative chylothorax management . His work includes developing prediction models for early chylothorax detection and evaluating vasopressin's hemodynamic effects in Fontan circulation patients. He has contributed to clinical practice guidelines for progressive pulmonary hypertension in children. His recent publications emphasize procedural efficiency in outpatient cardiac catheterization, valve repair durability in congenital heart disease, and standardized chylothorax algorithms . He utilizes multicenter collaborative frameworks and retrospective cohort analyses , with methodological approaches including logistic regression , Cox proportional hazards modeling , and consensus-building surveys . Key technical areas include lymphatic interventions , hemodynamic monitoring , and predictive analytics in pediatric cardiology. In clinical operations, he investigates same-day discharge criteria for pulmonary hypertension patients and optimal timing for advanced therapies . His work addresses practice variations in chylothorax treatment through quality improvement initiatives , including multidisciplinary algorithm development and ex vivo simulation testing for clinical implementation.

• Neuroscience
• Anesthesiology
• Brain Imaging
• +۳ مورد دیگر

Dr. Helene Benveniste is a Professor of Anesthesiology at Yale School of Medicine, specializing in neuroimaging and neurodegenerative diseases. She holds a dual background in Mathematics/Physics (BSc, Katedralskolen) and Medicine (MD and PhD in Neurobiology from University of Copenhagen). Her research focuses on the glymphatic system, cerebrospinal fluid dynamics, and brain waste clearance in aging and neurodegenerative diseases like Alzheimer’s. She has pioneered MRI/PET techniques for studying these processes and contributed to understanding cerebral amyloid angiopathy. Affiliations include the Anesthesiology Department, Yale Biomedical Imaging Institute, and the Center for Brain & Mind Health. Collaborators include Douglas Rothman, D. S. Fahmeed Hyder, and Kevin Behar. Her work spans clinical trials (e.g., SEMALCO trial for alcohol use disorder) and translational research, with over 100 publications. Notable 2025 studies address brain aging, CSF pathways, and glymphatic transport mechanisms. Education: • PhD in Neurobiology, University of Copenhagen (1991) • MD, University of Copenhagen (1986) Research Interests: • Glymphatic system function and dysfunction • Cerebrospinal fluid dynamics in health/disease • Neuroimaging techniques (MRI/PET) • Alzheimer’s and other neurodegenerative diseases • Brain clearance pathways in aging Publications Trends: Recent work emphasizes brain aging, CSF transport, and translational applications like clinical trials for alcohol use disorder. Key themes include glymphatic system dysfunction in neurodegeneration, fluid dynamics modeling, and biomarker discovery. Labs/Teams: Leads a research lab at Yale investigating glymphatic pathways and their role in disease. Collaborates with engineering and mathematics teams to model fluid flows using optimal mass transport algorithms.

Paul W Burridgeمشاهده پروفایل

دانشیار

• Pharmacogenomics
• Cardio-Oncology
• Induced Pluripotent Stem Cell Modeling
• +۵ مورد دیگر

Paul W Burridge, PhD is an Associate Professor in the Department of Pharmacology at Northwestern University's Feinberg School of Medicine and a founding faculty member of the Center for Pharmacogenomics. His laboratory specializes in human induced pluripotent stem cell (hiPSC) modeling for pharmacogenomics and cardio-oncology research. Dr. Burridge's research focuses on understanding how genomic variation influences drug efficacy and toxicity, particularly in cancer therapy-induced cardiovascular complications. His lab pioneered several key methodologies including the first directed cardiac differentiation protocol, non-integrating blood-to-iPSC reprogramming, and chemically defined differentiation protocols. Current projects span cardio-oncology, arrhythmia mechanisms, regenerative medicine, hiPSC models of breast cancer, and cultivated meat applications. Analysis of his 15 most recent publications reveals a strong emphasis on pharmacogenomics of anthracycline cardiotoxicity, with significant focus on genomic risk prediction in childhood cancer survivors, molecular mechanisms of cardiotoxicity, and development of cardioprotective strategies. His work increasingly integrates large-scale genomic analysis with hiPSC modeling to establish causal relationships between genetic variants and clinical outcomes. Fellow of American Heart Association (2016) Recipient of NCI R01 grant for Nilotinib Induced Artery Disease research NIH NHLBI Pathway to Independence Award recipient Editorial Board Member, Journal of Molecular and Cellular Cardiology (2020-present) Associate Editor, JACC CardioOncology (2018-present) Dr. Burridge advises multiple postdoctoral fellows including Ning Ge (cardiac arrhythmia modeling), Praeploy Pongpamorn (chemically defined differentiation), Nnamdi Uche (population-specific doxorubicin susceptibility), and George Gibbons. His lab has secured substantial grant funding for projects including large-scale hiPSC production, cardiotoxicity screening platforms, and novel drug discovery initiatives. The Burridge lab maintains extensive resources including high-throughput screening systems, CRISPR editing platforms, and bioreactor-based differentiation systems, all developed with a focus on eliminating animal-derived products from research.

Ngan F. Huangمشاهده پروفایل

دانشیار

• Tissue Engineering
• Cardiovascular Regeneration
• Stem Cell Therapy
• +۶ مورد دیگر

Ngan F. Huang, PhD is an Associate Professor of Cardiothoracic Surgery at Stanford University and a Courtesy Associate Professor of Chemical Engineering . She serves as a Research Career Scientist at the Department of Veterans Affairs and leads the Huang Research Lab at the Center for Tissue Regeneration, Repair and Restoration (VA Palo Alto Health Care System). Key roles: Principal Investigator, Stanford Cardiovascular Institute Research focus: Tissue Engineering , Cardiovascular Regeneration , Stem Cell Therapy , and Biomaterials Her work leverages extracellular matrix (ECM) cues, nanofibrillar scaffolds , and organ-on-a-chip platforms to address conditions like peripheral artery disease , muscle injury , and cardiovascular dysfunction . Recent publications emphasize combinatorial ECM designs , microgravity muscle modeling , and aligned fibrillar structures for cell orientation. Notable awards include the Peripheral Vascular Disease Travel Award (2014) and Robert W Hobson II Early Career Investigator Award (2012). Her lab actively recruits postdoctoral fellows and animal technicians for studies involving vascular disease models and tissue regeneration .

Roger Dale Kammمشاهده پروفایل

استاد

• Microfluidics
• Cell mechanics
• Biological systems
• +۶ مورد دیگر

Roger Dale Kamm is the Cecil and Ida Green Distinguished Professor at the Massachusetts Institute of Technology (MIT) in the departments of Mechanical Engineering and Biological Engineering . As a leading figure in mechanobiology, he directs the NSF Center on Emergent Behaviors of Integrated Cellular Systems and co-chairs the MIT faculty. His research focuses on microfluidic models for diseases such as metastatic cancer , Alzheimer’s , and ALS , with an emphasis on integrated cellular systems and living machines . His work bridges cell mechanics , biological systems , and vascular engineering , producing organ-on-a-chip and vascularized organoids for drug screening and disease modeling. Recent publications highlight innovations in neurovascular barriers , mechanical memory in cancer metastasis , and glymphatic system studies for neurodegenerative diseases. His lab develops 3D microfluidic platforms to simulate cardiovascular dynamics , neurological disease , and immune cell trafficking . Scientific Awards : National Academy of Engineering Fellow (2020) Shu Chien Achievement Award (2020) Nerem Medal (2018) Huiskes Medal (2015) Everett Moore Baker Award (2001) He has mentored numerous researchers and graduate students, including Ellen Kan and Marie Floryan . His Mechanobiology Lab at MIT pioneers microphysiological systems for vascular, neurological, and oncological applications, partnering with biotech/pharma for translational research.

• Microfluidics
• Bioengineering
• Biomedical Engineering
• +۴ مورد دیگر

Dr. Isaac Lee is an Assistant Professor and Nancy and Peter Meinig Family Investigator in the Life Sciences at Cornell University's Meinig School of Biomedical Engineering. He leads the Lee Lab, focusing on interdisciplinary research at the intersection of engineering, biology, and medicine to advance human health. Education : B.S. (Summa Cum Laude) in Chemical Engineering from Seoul National University (2006), M.S. in Pharmacy (2008), Ph.D. in Bioengineering from Johns Hopkins University (2014), and postdoctoral training at Harvard University's Wyss Institute and Boston University (2019). Research Interests include microfluidics, tissue engineering, lymphatic biology, cancer biology, and regenerative medicine. His lab develops 3D organ-on-chip systems to study lymphatic dysfunction, cancer metastasis, and immune diseases, with a focus on mechanistic insights from biological and mechanical cues. His recent articles highlight advancements in lymphatic valve dysfunction modeling, glymphatic system simulations, and biomaterials for cancer metastasis studies. Dr. Lee has received prestigious awards such as the NSF Career Award (2024) and the Tien Excellence in Teaching Award (2023). He teaches core biomedical engineering courses like Introduction to Biomedical Engineering and Cancer and Immuno-Engineering . His lab collaborates on projects like targeting protein mechanisms in lymphedema and advancing biomaterials for therapeutic applications.

Julia Castleberryمشاهده پروفایل

دانشیار

• Neurological Rehabilitation
• Geriatric Successful Living Strategies
• Falls Prevention
• +۴ مورد دیگر

Julia Castleberry is an Associate Professor of Physical Therapy at Emory & Henry University’s School of Health Sciences. She holds a DHSc from Radford University-Carilion (2021) and has over 30 years of clinical and academic experience in neurology, geriatrics, and oncology. Her work focuses on falls prevention, lymphedema therapy, and stroke rehabilitation. She co-founded the Falls Prevention Center, emphasizing lifespan wellness and community programs. Castleberry serves on numerous professional boards, including the American Physical Therapy Association’s Neurology Section and Brain Injury Services of Southwest Virginia. She is a certified Dementia Practitioner, Lymphedema Therapist, and LSVT-BIG provider. Education: Doctor of Health Science (DHSc), Radford University-Carilion (2021) Transitional Doctor of Physical Therapy (t-DPT), Virginia Commonwealth University (2011) Master of Science in Physical Therapy, Duke University (1993) Bachelor of Science in Biology, Virginia Tech (1990) Research & Professional Contributions: Castleberry leads studies on falls prevention, chronic disease management, and telehealth for veterans with brain injuries. Her funded projects include a study on Appalachian Trail hikers’ health and a longitudinal program for Parkinson’s, MS, and obesity patients. She has authored peer-reviewed articles, presented nationally, and developed educational programs like the CLiC-Wounded Warrior initiative. Teaching & Service: She teaches courses in neuroscience, neuromuscular therapy, and rural health. She chairs curricular committees and interprofessional education initiatives at Emory & Henry. Her roles in professional organizations include leadership in the Virginia Physical Therapy Association and APTA Neurology Section.

• Brain Energy Metabolism
• Magnetic Resonance Imaging (MRI)
• Molecular Imaging
• +۵ مورد دیگر

Dr. D. S. Fahmeed Hyder is a Professor of Radiology & Biomedical Imaging and Biomedical Engineering at Yale University, with joint appointments in the Yale School of Medicine. He leads the Magnetic Resonance Research Center (MRRC) and directs the Core Center for Quantitative Neuroscience with Magnetic Resonance (QNMR). His research focuses on brain energy metabolism, developing advanced MRI techniques to study neuronal-glial interactions, metabolic dysfunction biomarkers, and molecular imaging of tumors. He holds over 240 peer-reviewed publications and has secured continuous NIH funding for 25+ years. Education: B.A. in Chemistry (Wabash College, 1990), Ph.D. in Biophysical Chemistry (Yale University, 1995). Postdoctoral training includes roles at Oak Ridge National Laboratory, University of Rochester, and Yale. Research Interests: Functional MRI (fMRI) advancements, calibrated fMRI for quantitative neural activity, BIRDS molecular imaging (for pH/temperature), and applications in neurodegenerative diseases (e.g., Alzheimer’s) and oncology. Current projects include pH biosensor development, tumor response monitoring, and neuropil density prediction via AI. Awards: Melvin H. Knisely Award, Niels Lassen Award, Lundbeck Visiting Professorship, and fellowships in AIMBE, ARBR, and Sigma Xi. Recently appointed Head of Trumbull College at Yale. Grants: Continuous NIH support across 7 institutes; active projects in molecular imaging, stroke models, and neurovascular coupling. Labs/Teams: MRRC (mrrc.yale.edu), QNMR (qnmr.yale.edu), collaborating with interdisciplinary teams in physics, engineering, and biology.

• Vascular Biology
• Inflammation
• Atherosclerosis
• +۳ مورد دیگر

Hai Feng Zhang is an Associate Research Scientist in the Department of Pathology at Yale University School of Medicine. His research focuses on vascular biology and inflammation-driven diseases, particularly exploring mechanisms of endothelial dysfunction in conditions like atherosclerosis and cerebral cavernous malformations (CCM). He holds a PhD from the National University of Singapore and degrees from China Agricultural University. Education: PhD, National University of Singapore MS, China Agricultural University, Endocrinology BS, China Agricultural University, Biochemistry and Physiology Research Interests: His work investigates how inflammatory signals (e.g., TNF) and reactive oxygen species disrupt endothelial homeostasis. Key areas include: - Molecular mechanisms of vascular inflammation - Role of SUMOylation in vascular remodeling - Mitochondrial dysfunction in endothelial pathologies - CCM pathogenesis and therapeutic targets Key Contributions: Recent studies have uncovered roles for SRF SUMOylation in smooth muscle differentiation and identified mitochondrial pathways (TRX2, ATPIF1) critical for vascular health. Collaborations with teams like the Jenny Zhou Lab advance understanding of brain endothelial progenitor signaling and CCM development. Labs/Teams: Active member of the Jenny Zhou Lab, collaborating on translational vascular research projects.

Mariappan Muthuchamyمشاهده پروفایل

استاد

• Cardiac Muscle Physiology
• Lymphatic System Biology
• Mechanotransduction
• +۴ مورد دیگر

Mariappan Muthuchamy is a Professor of Medical Physiology and Director of the Cardiovascular Research Institute at Texas A&M University. His research focuses on cardiac and lymphatic muscle contraction mechanisms, mechanotransduction signaling, and the interplay between mechanical forces and cellular functions. He holds the Lyndon Baines Johnson Research Award. Education: B.S. Chemistry, Madurai Kamaraj University, India (1980) M.S. Biochemistry, Madurai Kamaraj University, India (1983) Ph.D. Biochemistry/Molecular Biology, Madurai Kamaraj University, India (1991) Research Interests: Dr. Muthuchamy’s work explores molecular mechanisms underlying cardiac muscle dynamics in health and disease, including thin filament activation, crossbridge kinetics, and mechanotransduction. His lab employs molecular, cellular, and structural techniques to study myofilament regulation. He pioneered methods to exchange myofibrillar proteins via transgenic manipulation. Additionally, he investigates lymphatic muscle contraction, its role in fluid transport, and its unique smooth-striated hybrid contractile properties. Recent work includes studying lymphatic dysfunction in metabolic disorders and inflammatory conditions using advanced tools like Atomic Force Microscopy (AFM) and microphysiological systems (e.g., Lymphangion-Chip). Key Findings: Established AFM-fluorescence microscopy fusion for mechanotransduction studies. Discovered lymphatic muscle’s role in systemic fluid dynamics and disease pathogenesis (e.g., lymphedema, metabolic syndrome). Linked inflammatory mediators (e.g., IL-1β, TNF-α) to lymphatic pump impairment. Awards: Lyndon Baines Johnson Research Award (Lyndon Baines Johnson Foundation) Lab & Collaborations: His lab includes Research Assistant Akshaya Narayanan (akshaya.narayanan@tamu.edu). Collaborations focus on translational research in cardiovascular and lymphatic physiology, leveraging engineered tissues and animal models. Ongoing projects target lymphatic dysfunction in amyotrophic lateral sclerosis, Duchenne muscular dystrophy, and metabolic diseases. Labs/Teams: Cardiovascular Research Institute (CRI) at Texas A&M, with interdisciplinary teams studying mechanobiology, integrin signaling, and lymphatic-inflammatory interactions.

Stephen E. Braunمشاهده پروفایل

استادیار

• Gene Therapy
• HIV/AIDS Research
• Virology
• +۵ مورد دیگر

Stephen E. Braun is an Assistant Professor of Pharmacology at Tulane University. His research focuses on gene therapy strategies targeting lympho-hematopoietic cells, with a strong emphasis on HIV/AIDS research. He has over 25 years of experience in translational research, including studies in non-human primates (NHP) and clinical trial advancements. His work involves developing CAR T-cell therapies, lentiviral vector engineering, and mesenchymal stem cell-based antiviral approaches. Education: BS in Genetics and Cell Biology, Biochemistry, University of Minnesota (1987) PhD in Genetics, University of Minnesota (1993) Postdoctoral Fellowship at Walther Oncology Center, Indiana University School of Medicine (1993–1997) Research Interests: Dr. Braun’s lab develops novel gene therapy approaches to combat HIV/AIDS, including CAR T-cell redirection, HIV-resistant T-cell engineering, and MSC-mediated viral inhibition. His work bridges in vitro studies with large-animal models and clinical application. Key Awards: NIH Post-Doctoral Training Award (1993–1995) Leukemia Society of America Fellow Award (1995–1998) Center for AIDS Research Scholar Award (2003–2006) Early Investigator Award (30th Annual NHP AIDS Symposium, 2012) Grants & Collaborations: His research has been supported by NIH and private foundations. Collaborations span institutions such as the National Primate Research Centers and the American Society of Gene & Cell Therapy. Labs/Teams: Active in Tulane’s Division of Veterinary Medicine and collaborates with the Comparative Pathology and Immunology research groups.

Joseph Muddمشاهده پروفایل

استادیار

• HIV/AIDS Research
• Immunology
• Virology
• +۳ مورد دیگر

Joseph C. Mudd is an Assistant Professor in the Department of Microbiology and Immunology at Tulane University, leading the Mudd Laboratory within the Division of Immunology. His research focuses on understanding mechanisms of HIV-1 persistence and reservoir maintenance, particularly exploring interactions with co-infecting viruses like CMV and the impact of nutritional interventions on SIV pathogenesis. He holds a PhD from Case Western Reserve University. Research Interests: Latent HIV reservoir dynamics CMV-driven immune activation and reservoir persistence Nutritional regulation of viral pathogenesis Immunometabolic pathways in chronic infections Funding: ORIP/NIH: $400,000 (Mechanisms of CD4 down-regulation in African green monkeys) NIAID/NIH: $5.1M (Role of RhCMV in SIV reservoir persistence) Laboratory Team: Ph.D. students Naveen Suresh Babu and Maggie Hallmet, Post-Doc Chrysostomos Perdios, and Research Technician Celeste D. Collaborators include prominent researchers like Clovis Palmer and Joshua Schiffer. Lab Location: 18703 Three Rivers Road, Covington, LA 70433

Lauren M. Hablitzمشاهده پروفایل

استادیار

• Circadian Rhythms
• Glymphatic System
• Neurodegenerative Diseases
• +۳ مورد دیگر

Lauren M. Hablitz is an Assistant Professor in the Department of Neurology at the University of Rochester Medical Center , where she leads the Hablitz Lab at the Center for Translational Neuromedicine . Her research focuses on circadian synchrony , glymphatic system function , and chronotherapy in chronic neuropathic pain and stroke . Education: B.S. in Biology from Pennsylvania State University (2010) Ph.D. in Cell, Molecular, and Developmental Biology from University of Alabama at Birmingham (2015) Dr. Hablitz defined the endogenous circadian rhythm of the glymphatic system and discovered CSF distribution rhythms between brain and mandibular lymph nodes . Her work bridges circadian biology and neurovascular function , exploring how chronotherapy can improve outcomes in neurodegenerative diseases and pain disorders . Article trends show her team's focus on glymphatic system dysfunction in chronic pain models , Aquaporin-4 mechanisms , circadian disruption effects on neurovascular integrity , and peptidergic regulation via VIP/AVP signaling . Key technical approaches include in vivo imaging , confocal microscopy , and mass spectrometry . Scientific Awards: 2021 Outstanding Early Investigator Award 2020 Merit Award 2016 Tartar Trust Foundation Fellowship 2014 Trainee Award The Hablitz Lab collaborates with Dr. Maiken Nedergaard and includes Emma Waight (Technical Associate) and Eevalien Duyvesteyn (Research Assistant) . Projects span glymphatic dysfunction in chronic pain , circadian stroke rhythms , and lymphatic-glymphatic homology , using murine models and molecular manipulation .

• Vascular Biology
• Atherosclerosis
• Single-Cell Genomics
• +۳ مورد دیگر

Jianing (Jenny) Gao is a Postdoctoral Fellow conducting cutting-edge research in vascular biology and cardiovascular diseases, with a focus on molecular mechanisms underlying atherosclerosis, lymphatic development, and metabolite-mediated intercellular communication. Her work bridges experimental biology and computational approaches to address critical questions in vascular pathophysiology. Her primary research interests include: Vascular Biology Atherosclerosis Single-Cell Genomics Machine Learning in Biomedicine Cardiovascular Metabolism Lymphatic Development Analysis of her publication record (2021-2025) reveals consistent emphasis on endothelial cell identity, lymphatic valve formation, and gut microbiota-derived metabolites' roles in cardiovascular pathologies. Key trends include the application of machine learning to decode vascular cell identity genes, mechanistic studies of S1PR1 signaling in lymphatic development, and clinical investigations linking metabolites like trimethylamine N-oxide to heart failure and pulmonary hypertension outcomes.