معرفی
Dr. Helene Benveniste is a Professor of Anesthesiology at Yale School of Medicine, specializing in neuroimaging and neurodegenerative diseases. She holds a dual background in Mathematics/Physics (BSc, Katedralskolen) and Medicine (MD and PhD in Neurobiology from University of Copenhagen). Her research focuses on the glymphatic system, cerebrospinal fluid dynamics, and brain waste clearance in aging and neurodegenerative diseases like Alzheimer’s. She has pioneered MRI/PET techniques for studying these processes and contributed to understanding cerebral amyloid angiopathy.
Affiliations include the Anesthesiology Department, Yale Biomedical Imaging Institute, and the Center for Brain & Mind Health. Collaborators include Douglas Rothman, D. S. Fahmeed Hyder, and Kevin Behar.
Her work spans clinical trials (e.g., SEMALCO trial for alcohol use disorder) and translational research, with over 100 publications. Notable 2025 studies address brain aging, CSF pathways, and glymphatic transport mechanisms.
Education:
• PhD in Neurobiology, University of Copenhagen (1991)
• MD, University of Copenhagen (1986)
Research Interests:
• Glymphatic system function and dysfunction
• Cerebrospinal fluid dynamics in health/disease
• Neuroimaging techniques (MRI/PET)
• Alzheimer’s and other neurodegenerative diseases
• Brain clearance pathways in aging
Publications Trends:
Recent work emphasizes brain aging, CSF transport, and translational applications like clinical trials for alcohol use disorder. Key themes include glymphatic system dysfunction in neurodegeneration, fluid dynamics modeling, and biomarker discovery.
Labs/Teams:
Leads a research lab at Yale investigating glymphatic pathways and their role in disease. Collaborates with engineering and mathematics teams to model fluid flows using optimal mass transport algorithms.
