جستجوی استاد راهنمای دانشگاهی

Alexis Battleمشاهده پروفایل

دانشیار

• Genomics
• Machine Learning
• Computational Biology
• +۳ مورد دیگر

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

• Nanomedicine
• Drug Delivery Systems
• Cellular Uptake of Nanoparticles
• +۳ مورد دیگر

Anna Salvati is an Associate Professor specializing in nanomedicine and drug delivery systems. Her research focuses on nanoparticle-cell interactions, biomolecular corona formation, and the physicochemical properties governing nanomaterial behavior in biological environments. Key research themes include cellular uptake mechanisms, toxicity of nanomaterials, and nanoparticle targeting strategies. Recent publications highlight her work on nanoparticle stability, membrane interactions, and environmental impacts of microplastics. Her studies integrate multiomics approaches, advanced imaging, and interlaboratory validation to address challenges in nanomedicine design and safety testing. Current projects explore the role of high-density lipoproteins in nanoparticle functionality and the modulation of drug release kinetics through material engineering.

Michael Krisingerمشاهده پروفایل

دانشگاهی

• Biochemistry
• Molecular Biology
• Coagulation
• +۳ مورد دیگر

Michael Krisinger is an Associate Professor of Teaching in the Department of Biochemistry & Molecular Biology at the University of British Columbia . He began his teaching career in 2010, transitioning to full-time in 2013. He lectures Biochemistry 202 (Introductory Medical Biochemistry) and Biochemistry 303 (Molecular Biochemistry) while serving as a tutor in the Faculty of Medicine's Case Based Learning program. Krisinger co-developed the department's two-course summer program for international students and mentors postdoctoral fellows in teaching. He also manages the department's CANVAS digital learning platform. Krisinger's research focuses on the molecular mechanisms of coagulation and complement system regulation , particularly their evolutionary relationship and functional interplay. His work has explored thrombin's role in complement activation, polyphosphate-mediated complement suppression, and nanoparticle surface interactions with proteolytic cascades. He previously co-supervised graduate students at UBC's Centre for Blood Research before prioritizing education. Publications highlight his expertise in protease-substrate dynamics , lipoprotein-phospholipid interactions , and hemostasis-immunity crosstalk . He remains engaged in public science through community environmental initiatives and local outreach activities.

Allan Davidمشاهده پروفایل

استاد

• Smart Materials
• Nanomedicine
• Cancer Research
• +۴ مورد دیگر

Allan David serves as the John W. Brown Professor of Chemical Engineering and Associate Dean for Research at Auburn University's Samuel Ginn College of Engineering. His leadership extends across academic administration and cutting-edge nanomedicine research, with a focus on translating laboratory discoveries into clinical applications. His educational foundation includes: Ph.D. in Chemical Engineering, University of Maryland B.S. in Chemical Engineering, University of Maryland Dr. David's research program pioneers nanomedicine applications through the development of smart materials for cancer diagnostics and therapy. His work spans nanoparticle-based MRI contrast agents , ocular drug delivery systems , and vaccine delivery platforms , with particular emphasis on optimizing physicochemical properties for targeted biological interactions. Current projects address critical healthcare challenges including safer contrast agents for patients with kidney impairment and precision cancer targeting mechanisms. Analysis of his 15 most recent publications reveals a cohesive research trajectory centered on magnetic nanoparticles and biomimetic delivery systems . The work demonstrates increasing translational focus, evolving from fundamental nanoparticle characterization (2020-2021) to clinically relevant applications like ocular delivery and cancer theranostics (2022-2024), culminating in commercialization efforts through NanoXort, LLC. Dr. David has secured significant research funding including an $184,773 grant from the Alabama Department of Economic and Community Affairs (ADECA) for developing cardiovascular MRI agents. He leads collaborative efforts that bridge chemical engineering with biomedical innovation, notably co-founding NanoXort, LLC to commercialize safer MRI contrast agents addressing gadolinium toxicity concerns for renal-impaired patients. His laboratory operates at the intersection of chemical engineering and medicine, focusing on nanoparticle-cell interactions and targeted delivery systems. The research group maintains strong industry partnerships through the NanoXort startup, which has secured $1 million NSF funding to advance MRI contrast agent technology toward clinical implementation.

Wouter Roosمشاهده پروفایل

استاد

• Biophysics
• Biochemistry & Molecular Biology
• Nanoscience & Nanotechnology
• +۵ مورد دیگر

Prof. Wouter Roos is a Professor at the University of Groningen's Faculty of Science and Engineering, affiliated with the Molecular Biophysics department at the Zernike Institute for Advanced Materials. His research focuses on viral dynamics, membrane assemblies, and protein mechanics, utilizing advanced techniques like High Speed Atomic Force Microscopy (HS-AFM) and optical tweezers. Education: Studied Physics at the Universiteit van Amsterdam, earned a PhD from the Universität Heidelberg under Joachim Spatz. Conducted postdoctoral research at Max-Planck-Institut, Institut Curie, and Vrije Universiteit before joining Groningen in 2015. Research Interests: Physical Virology (viral material properties and dynamics), membrane biophysics (synthetic cells and lipid interactions), and molecular motor systems. His work bridges physics, chemistry, and biology to understand nanoscale biological processes. Recent Article Trends: Studies on hybrid membranes for synthetic cells, leukemic cell mechanics, and antibiotic-membrane interactions highlight his interdisciplinary approach. Key techniques include HS-AFM and single-particle tracking. Awards: Received a VIDI grant and multiple national/international grants. His lab leads the oLife Co-Fund consortium and participates in the MOSBRI research infrastructure. Grants & Leadership: Coordinates the oLife Fellowship Programme and chairs the Molecular Biophysics Lab. Active in steering committees for EU-funded initiatives. Labs/Teams: Heads the Molecular Biophysics Lab, focusing on viral dynamics and membrane systems. Collaborates globally on projects like ESCRT-III polymerization and antibiotic mechanisms.

Thomas J. D. Jørgensenمشاهده پروفایل

دانشیار

• Mass Spectrometry
• Hydrogen/Deuterium Exchange
• Protein Structural Dynamics
• +۷ مورد دیگر

Thomas J. D. Jørgensen is an Associate Professor and Head of the Research Section of Biomedical Mass Spectrometry at the Department of Biochemistry and Molecular Biology, University of Southern Denmark. He leads an active research group focusing on protein structural dynamics using mass spectrometry and hydrogen/deuterium exchange methodologies. His research interests lie at the intersection of biochemistry, structural biology, and systems biology, particularly in understanding how protein dynamics govern function and dysfunction in diseases such as Parkinson’s and metabolic disorders. He employs advanced mass spectrometry techniques to study conformational changes, protein-protein interactions, and enzyme regulation, with a strong emphasis on lipoprotein metabolism and neurodegenerative disease mechanisms. The most recent articles highlight a consistent focus on protein dynamics in lipid metabolism, conformational diseases, and glycoprotein analysis, utilizing hydrogen/deuterium exchange mass spectrometry (HDX-MS) and related techniques. Themes include allosteric regulation of enzymes, protein unfolding, and structural phenotyping of disease-related aggregates. Member of the evaluation committee at the Swedish Research Council (2015) Chairman of multiple PhD evaluation committees (2014) Editorial and peer-review contributions to the scientific community He currently supervises PhD students and is involved in several major research projects funded by organizations such as the Michael J. Fox Foundation and Novo Nordisk Fonden. His lab, the Thomas J. D. Jørgensen Lab, includes postdoctoral researchers, academic staff, and industrial PhD students, fostering a collaborative and interdisciplinary research environment focused on biomedical mass spectrometry and systems biology.

Xin Luمشاهده پروفایل

دانشیار

• Cancer Biology
• Tumor Microenvironment
• Tumor Immunology and Immunotherapy
• +۱۲ مورد دیگر

Xin Lu is the John M. and Mary Jo Boler Collegiate Associate Professor in the Department of Biological Sciences at the University of Notre Dame. She is a full member of the Harper Cancer Research Institute (HCRI), the Boler-Parseghian Center for Rare and Neglected Diseases (CRND), and the Tumor Microenvironment and Metastasis Program at the Indiana University Simon Comprehensive Cancer Center. Her research spans tumor immunology, immunotherapy, metastasis, and multi-omics, with a focus on prostate, breast, and rare cancers. Ph.D. in Molecular Biology, Princeton University (2004–2010) B.S. in Biological Sciences, Tsinghua University, China (2000–2004) Postdoctoral Fellow, Dana-Farber Cancer Institute and M.D. Anderson Cancer Center (2010–2016) Assistant to Associate Professor, University of Notre Dame (2017–Present) Dr. Lu's research investigates the molecular and cellular mechanisms of tumor-immune crosstalk, particularly the role of myeloid-derived suppressor cells (MDSCs) and neutrophils in promoting immunotherapy resistance. Her lab uses genetically engineered mouse models, functional genomics, single-cell and spatial transcriptomics, and high-throughput screening to uncover novel therapeutic targets. A major focus is on how cancer-cell-intrinsic oncogenic signaling shapes the immunosuppressive tumor microenvironment. Her recent publications reveal mechanisms such as Acod1-mediated ferroptosis resistance in neutrophils, Pygo2-driven immunosuppression in prostate cancer, and the efficacy of ketogenic diets in overcoming checkpoint blockade resistance. These studies span multiple disciplines including cancer biology, immunology, metabolism, epigenetics, and bioengineering, reflecting a highly integrative approach to immuno-oncology. Jane Coffin Childs Postdoctoral Fellow John M. and Mary Jo Boler Faculty Appointment Cluster Chair, Cellular & Molecular Biology, IBMS PhD Program Junior Chair, Boler-Parseghian Center for Rare and Neglected Diseases Dr. Lu mentors a diverse team of graduate students, postdoctoral fellows, and undergraduates. Her lab is actively recruiting and has secured funding from federal agencies and private foundations. She collaborates with chemists, bioengineers, and bioinformaticians to develop novel therapeutics, including antibody-drug conjugates, CAR-NK cells, and small-molecule inhibitors. Her lab also develops innovative platforms like mini-tumor chips for immunotherapy evaluation. Her lab maintains affiliations with multiple interdisciplinary centers including the Warren Family Center for Drug Discovery, Eck Institute for Global Health, and Berthiaume Institute for Precision Health, underscoring her collaborative and translational research vision.

• Computational Biophysics
• Membrane Proteins
• Protein Dynamics
• +۵ مورد دیگر

Régis Pomès is a Professor in the Department of Biochemistry at the University of Toronto, where he leads an active research program since 1999. His work focuses on computational biophysics, studying the structure-dynamics-function relationships of biomolecules. Canada Research Chair (Tier 2) in Physical Chemistry (2001-2011) Teaches courses: BCH 2107H: Introduction to Biomolecular Simulations BCH 2105H: Cystic Fibrosis: The Cause, The Treatment BCH 2024H: Introduction to Biomolecular Simulations JBB2026H: Protein Structure, Folding and Design BCH473Y: Advanced Research Project in Biochemistry BCH422H: Membrane Proteins: Structure and Function Research Interests: The Pomès Lab specializes in computational methods development and their application to biomolecular systems, particularly: Membrane proteins and ion channels Protein-lipid interactions Protein folding and aggregation Statistical mechanics of biomolecular systems Molecular dynamics simulations across multiple scales Structural biology of disordered proteins Awards: Canada Research Chair (Tier 2) in Physical Chemistry (2001-2011)

• Genetics
• Biometry
• Public Health
• +۷ مورد دیگر

Samuli Ripatti is a Professor of Biometry at the Faculty of Medicine, University of Helsinki, and Director of the Institute for Molecular Medicine Finland (FIMM). He chairs the Research Council Finland’s Centre of Excellence in Complex Disease Genetics and the EU H2020-funded Intervene Consortium. His research focuses on genetic variation in the Finnish population, particularly its effects on cardiometabolic diseases and cancers, with a strong emphasis on polygenic risk scores for disease prevention and early detection. His work spans Genetic risk prediction models Lipidomic and metabolomic profiling Gene-environment interactions Translational genomics Recent research highlights include 1099 plasma metabolite-disease causal analysis Genetic determinants of weight loss interventions Cardiovascular risk stratification tools Leukocyte lipid metabolism pathways He actively supervises doctoral programs in Integrative Life Science, Social Sciences, Clinical Research, and Population Health, and collaborates with the Broad Institute of MIT and Harvard.

Linda Sandbladمشاهده پروفایل

دانشیار

• Cytoskeleton
• Electron Microscopy
• Bacterial Model Organisms
• +۲ مورد دیگر

Linda Sandblad is Associate Professor at the Department of Chemistry, Umeå University, and Research Fellow at Molecular Infection Medicine Sweden (MIMS). She directs the Umeå Centre for Electron Microscopy and leads research into cytoskeletal organization using advanced imaging techniques. Her research investigates: FilP protein dynamics in Streptomyces coelicolor bacterial model Keratin filament assembly in epithelial tissues Microtubule dynamics and associated protein functions Advanced electron microscopy method development Recent publications demonstrate applications of cryoelectron tomography, fluorescence imaging, and structural analysis across bacterial and eukaryotic systems, with particular focus on membrane proteins, cellular division mechanisms, and host-pathogen interactions. She received the Bo and Barbro Hammarström Prize for outstanding contributions to research infrastructure development.

• Autophagy
• Cell Biology
• Membrane Biology
• +۳ مورد دیگر

Thomas Melia is a Professor of Cell Biology at the Yale School of Medicine, part of Yale University. He leads the Melia Lab, focusing on autophagosome biogenesis and membrane dynamics during autophagy. His research integrates cell-based assays with advanced imaging techniques like electron cryo-microscopy. Key areas include understanding membrane sources for autophagosomes, lipid transport mechanisms, and organelle formation under cellular stress. Education: PhD in Biochemistry from Baylor College of Medicine (1999), BS in Biological Sciences from Carnegie Mellon University (1992) Research Interests: Autophagy, lysosomal biology, membrane trafficking, and protein aggregate clearance Lab Affiliations: Collaborates with departments like Biochemistry, Quantitative Biology, and Molecular Cell Biology Melia's work bridges molecular mechanisms with cellular function, particularly in how cells respond to starvation or pathogen invasion by degrading cytosolic components. Recent studies highlight roles for dynamin-like proteins in nuclear autophagy and lipid transfer proteins in organelle biogenesis.

Ronald Peggمشاهده پروفایل

استاد

• Functional foods
• Nutraceuticals
• Bioactive phytochemicals
• +۶ مورد دیگر

Ronald Pegg is the Josiah Meigs Distinguished Teaching Professor in the Food Science & Technology department at the University of Georgia's College of Agricultural & Environmental Sciences. His research focuses on functional foods, nutraceuticals, and the bioactive properties of phytochemicals, with expertise in separation and identification of bioactives, nutrient analysis, and lipid oxidation studies. He teaches courses ranging from introductory food science to advanced functional foods and analytical methods. Specializes in antioxidant activity of tree nuts, fruits, and legumes Develops analytical assays for food composition Studies shelf-life extension strategies for food products His recent work emphasizes cellular antioxidant activity, phenolic profiling, and encapsulation technologies. Awards include the Josiah Meigs Distinguished Teaching Professor title. Publications span journals in food chemistry, nutrition, and analytical science.

• Microbiology
• Infection Biology
• Immunology
• +۳ مورد دیگر

Prof. Friedrich Götz is a Senior Professor and Head of the Department of Microbial Genetics at the University of Tübingen, Germany. He has held this position since 2015, following his tenure as a full professor from 1987 to 2015. He is also a Visiting Professor at the Shiraz University of Medical Sciences (SUMS, 2020–present) and a member of the Cluster of Excellence - CMFI (2018–present). His academic journey includes a Ph.D. in Microbiology from Ludwig Maximilians University (LMU) Munich (1974–1978) and Habilitation at TU Munich (1985). His research focuses on microbial genetics, particularly the physiology of staphylococci, lipoprotein roles in immune responses, and bacterial-host interactions. Recent studies highlight microbiota-derived neurotransmitters influencing host cells and the development of novel antimicrobial compounds. His work has led to groundbreaking insights into skin microbiota's role in wound healing and neurochemical signaling. Prof. Götz has been awarded the DECHEMA Award (1989), DGHM Award (1991), and DGHM Lecturer Award (2009). He has served as President and Vice President of the VAAM (2003–2009), and has held leadership roles in major initiatives, including the DFG Graduate College 685 (2010–2011) and the Transregio SFB (2006–2013). He actively contributes to scientific publishing as an editor for journals like Molecular Microbiology and Medical Microbiology and Immunology, and advises international research institutions. His research spans over 380 peer-reviewed publications, with an h-index of 99, and has mentored over 120 PhD students and postdocs, many of whom have become professors. His lab, part of the Interfaculty Institute for Microbiology and Infection Medicine (IMIT), collaborates globally on microbial genetics and infection biology.

Xi-Long Zhengمشاهده پروفایل

استاد

• Vascular Smooth Muscle Biology
• Atherosclerosis
• Vascular Disease Mechanisms
• +۴ مورد دیگر

Xi-Long Zheng is a tenured Professor in the Department of Biochemistry and Molecular Biology and Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary. He holds additional appointments as a Member of the Libin Cardiovascular Institute and Associate Member of both the Snyder Institute for Chronic Diseases and Arnie Charbonneau Cancer Institute. His research focuses on vascular smooth muscle biology and its role in cardiovascular diseases. Doctor of Medicine, Hunan Medical University (1986) M.S. in Pharmacology, Hunan Medical University (1989) Doctor of Philosophy in Pharmacology, University of Calgary (1997) Dr. Zheng's research centers on vascular smooth muscle cell differentiation, proliferation, and phenotypic switching in vascular diseases. His laboratory investigates mechanisms of vascular smooth muscle dedifferentiation in atherosclerosis, abdominal aortic aneurysms, and vascular stiffness. Current work explores ferroptosis, epigenetic regulation (particularly BRD4), and PCSK9 functions in vascular pathologies. His studies integrate molecular, cellular, and in vivo approaches to identify novel therapeutic targets for cardiovascular diseases. Analysis of his recent publications reveals strong emphasis on cell death mechanisms (ferroptosis, cuproptosis), epigenetic regulation, lipid metabolism, and immune-vascular interactions in atherosclerosis. His work demonstrates increasing focus on translational applications targeting vascular smooth muscle phenotypic switching and plaque stability. Alberta Innovates ‒ Health Solutions Senior Scholar Award (2008-2015) Heart & Stroke Foundation New Investigator Award (2001-2006) CIHR/Hypertension Society Scholarship Award (2001-2004) Heart & Stroke Foundation Fellowship Award (1999-2001) AHFMR Independent Investigator Award (2008) Dr. Zheng serves on grant panels for Canadian Institutes of Health Research and Heart and Stroke Foundation of Canada. He is an editorial board member for Biochemical Journal and other scholarly publications. His laboratory receives funding from CIHR and NSERC for projects including smooth muscle PCSK9 in abdominal aortic aneurysm pathogenesis, smooth muscle autophagy in vascular aging, and epigenetic regulation of smooth muscle plasticity. The Zheng Lab investigates vascular smooth muscle functions across multiple organ systems including blood vessels, gastrointestinal tract, bladder, and uterus. His research has established critical mechanisms in vascular smooth muscle differentiation and cell cycle regulation, contributing over 100 peer-reviewed publications in high-impact journals including PNAS, ATVB, Diabetologia, JBC, and Hypertension.

Elda Favariمشاهده پروفایل

دانشیار

• Pharmacology
• Toxicology
• Atherosclerosis
• +۳ مورد دیگر

Prof.ssa Elda Favari is a Full-Time Associate Professor of Pharmacology at the Department of Food and Drug, University of Parma, Italy . Her research focuses on atherosclerosis physiology , cholesterol metabolism , and cellular cholesterol efflux processes . She has collaborated with international institutions in the USA , Australia , and Switzerland . PhD in Pharmacology and Toxicology (University of Parma, 2005) Academic Editor for the journal Medicine Member of Italian Society of Pharmacology , European Lipoprotein Club , and International Atherosclerosis Society Her scientific contributions include over 50 peer-reviewed publications , an H-index of 23 , and 16 Q1-journal publications from the last 15 years. Key research areas cover reverse cholesterol transport , PCSK9 mechanisms , and HDL functionality in diseases like familial hypercholesterolemia , cancer , and autoimmune disorders . Recent Google Scholar publications (2023-2025) examine: HDL modulation through nutraceuticals and 3D-printed devices Immune checkpoint inhibitors in relation to lipid profiles PCSK9-lomitapide interactions in genetic lipid disorders Anti-ApoA-1 IgGs as atherogenic factors 2000: AstraZeneca Grant at SISA Congress 2011: National Research Grant for Lupus Study She has held institutional roles including Student Orientation Delegate and serves on scientific committees for international congresses. Teaching spans Toxicology , Anticancer Chemotherapy , and Pharmacovigilance across Pharmacy , Food Safety , and Drug Sciences programs.