جستجوی استاد راهنمای دانشگاهی

Martina Gentzsch, PhD, is an Associate Professor in the UNC School of Medicine at the University of North Carolina at Chapel Hill. She holds affiliations with the Marsico Lung Institute and the Cystic Fibrosis Research Center. Her research focuses on understanding cellular and molecular mechanisms of ion channel dysfunction in airway diseases, particularly cystic fibrosis (CF), with an emphasis on CFTR (cystic fibrosis transmembrane conductance regulator) restoration. Dr. Gentzsch’s work develops pre-clinical assays to evaluate novel CF therapies and investigates how environmental factors and tissue-specific contexts influence CFTR function. Education: PhD in Cell Biology (Glycoprotein Processing), University of Regensburg, Germany (1997) M.S. in Cell Biology, Biochemistry, Genetics, and Organic Chemistry, University of Regensburg, Germany (1993) B.S. in Cell Biology, Genetics, Physics, and Chemistry, University of Regensburg, Germany (1991) Research Interests: Dr. Gentzsch’s studies explore CFTR’s role across organs, rescue mechanisms in different tissues, and personalized CF therapy strategies. Her lab employs advanced cell biological and electrophysiological techniques to assess CFTR function in 2D and 3D airway models. Key areas include CFTR stability under inflammation, mucus properties, and translational models for drug testing. Awards: Adolf Windorfer Prize (2015) Marsico Scholar Award (2014) Profiled Author, Journal of Biological Chemistry (2010) Grants & Labs: Her research is supported by grants focusing on CF pathophysiology and therapy. Collaborations include work with the Cystic Fibrosis Foundation and industry partners. She leads studies in the Marsico Lung Institute, advancing precision medicine approaches for CF.

• Cystic Fibrosis
• Ion Channel Biology
• Cellular Trafficking
• +۳ مورد دیگر

Koen Gerard Alois Vervaeke is a Professor at the University of Oslo in the Faculty of Medicine , leading the Vervaeke Lab . His research focuses on understanding how brain circuits transform complex sensory inputs into coherent perceptions, with emphasis on dendritic integration and cortical network dynamics. 2011-2014: Janelia Farm Research Campus – Junior Fellow (Mentors: Karel Svoboda, Jeff Magee) 2007-2011: University College London – Postdoctoral Researcher (Angus Silver Lab) 2002-2007: University of Oslo – PhD in Physiology (Johan Storm Lab) Research Themes Neocortical processing of sensory information Dendritic integration of internal and external inputs Computational modeling of neural circuits Optogenetic manipulation in perceptual tasks In vivo two-photon imaging and electrophysiology Article Trends (2007-2025): Focus on hippocampal spatial coding (VIP interneurons, place cells), neocortical sensory integration, gamma oscillations, and astrocytic Ca 2+ signaling. Methodologies include in vivo imaging, dynamic clamp, and computational modeling. Scientific Awards ERC Starting Grant (2015) FRIPRO Young Research Talents Grant (2014) The lab combines experimental (mice behavioral studies, two-photon imaging) and computational approaches to model neural circuit operations. Their work aims to establish frameworks for understanding brain dysfunction in neuropsychiatric disorders.

• Neuroscience
• Computational Neuroscience
• Neural Circuits
• +۳ مورد دیگر

Dr. Francisco Rios is an Honorary Research Fellow at the University of Glasgow's School of Cardiovascular & Metabolic Health. His research focuses on cardiovascular biology, hypertension, oxidative stress, and vascular inflammation. He holds a Research Fellow academic rank and is actively involved in collaborative studies with institutions globally. Key research interests include mechanisms of vascular inflammation, NADPH oxidase signaling, magnesium's role in cardiovascular health, and exosome-mediated communication in disease. His work bridges basic science and clinical applications, particularly in hypertension and vascular dysfunction. Dr. Rios has contributed to over 60 peer-reviewed articles, with recent studies emphasizing therapeutic targets for vascular inflammation, genetic associations with endocrine disorders, and magnesium signaling pathways. He collaborates extensively with Professors Rhian Touyz and Augusto Montezano on vascular biology projects. He received grant support from the Medical Research Council (2016-2017) for the project 'P2D - Histoindex-Clinnovate Health UK'. His research also explores biomarkers of vascular inflammation and the impact of antiangiogenic therapies on cardiovascular systems.

• Cardiovascular Disease
• Hypertension
• Oxidative Stress
• +۳ مورد دیگر

Professor Peter Macfarlane is an Honorary Senior Research Fellow at the University of Glasgow's School of Health & Wellbeing. His career spans roles as Emeritus Professor and Professor of Electrocardiology, with a focus on applying computer techniques to ECG interpretation. He has contributed global guidelines on ECG definitions for myocardial infarction and established an ECG Core Lab for clinical trials. His work emphasizes ECG variability across age, gender, and ethnicity, and has influenced international medical practices. Research Interests: Development of automated ECG analysis systems ECG biomarkers in cardiovascular disease Impact of demographic factors on ECG patterns Post-COVID-19 cardiac sequelae Scientific Contributions: His University of Glasgow ECG program is globally used. Key awards include the Rijlant Prize (1998), DSc (2000), and CBE (2014). The lab he founded processes ECGs for national/international trials, advancing standardized cardiac evaluations. Grants & Collaborations: Funded projects include the CISCO-19 study on cardiac involvement post-COVID-19 and the PRIZE trial on angina treatment. Collaborations span cardiology, epidemiology, and computational medicine. Labs/Teams: Leads the Electrocardiology Section at the Royal Infirmary of Glasgow, fostering interdisciplinary research in cardiac electrophysiology and digital health.

• Electrocardiology
• Computer Techniques in ECG Interpretation
• Cardiology
• +۳ مورد دیگر

Kwang Jin Kim, Ph.D., is a Professor of Medicine at the University of Southern California's Keck School of Medicine, with secondary appointments in Physiology & Biophysics, Pharmacology & Pharmaceutical Sciences, and Biomedical Engineering. He earned his B.S. and M.S. in Electronics Engineering from Seoul National University (1971, 1973) and his Ph.D. in Bioengineering from the University of Pennsylvania (1980). His career includes postdoctoral training at UCLA and faculty positions at Cornell University Medical College before joining USC in 1991. Dr. Kim's research focuses on electrophysiology and pathophysiology of pulmonary and ocular epithelial barriers. Key areas include nanoparticle-alveolar interactions, autophagy mechanisms, ion transport regulation, and tight junction dynamics. His work employs advanced techniques like confocal microscopy, Ussing chambers, and genetic knockout models to study barrier functions. Recent publications demonstrate a strong focus on nanoparticle interactions with lung cells (uptake, trafficking, toxicity), autophagy modulation in disease contexts, and molecular regulation of alveolar fluid clearance. His lab frequently utilizes knockout mouse models to elucidate roles of claudins and transporters in lung homeostasis. Scientific Awards: Public Health Service New Investigator Award (1985-1988) American Heart Association Postdoctoral Fellowship (1980-1982) University of Pennsylvania Research Fellowship (1977-1980) He maintains active membership in professional societies including the American Physiological Society and American Association for the Advancement of Science. His laboratory investigates pulmonary and ocular barrier functions using electrophysiological, molecular, and imaging approaches.

• Epithelial Barrier Physiology
• Nanoparticle Transport
• Alveolar Fluid Clearance
• +۳ مورد دیگر

Prof. Dr. med. Johannes Loffing is a Full Professor at the Institute of Anatomy, University of Zurich since 2007. His research focuses on kidney ion balance mechanisms and their role in diseases like arterial hypertension. He holds a medical degree from the University of Münster (1993) and completed postdoctoral training at Dartmouth Medical School (USA). He has held academic roles at institutions including the University of Lausanne and University of Fribourg before returning to Zurich. His research is supported by the Swiss National Science Foundation, and he directs the NCCR Kidney.CH initiative. Education: MD, University of Münster (1993) Postdoctoral Fellowship, Dartmouth Medical School (1996–?) VENIA LEGENDI (Habilitation), University of Zurich (2003) Research Interests: Renal physiology, ion transport regulation, mechanisms of hypertension, and genetic kidney disorders. Specific topics include the role of sodium chloride cotransporters (NCC), aldosterone signaling, and molecular pathways in kidney dysfunction. Labs/Teams: Leads a research group including PhD candidates (e.g., Christian Keller), postdocs (e.g., Wouter van Megen), and technicians (e.g., Monique Carrel). Collaborates with institutions like the University of Zurich's Department of Pharmacology and the NCCR Kidney.CH network.

• Kidney Function
• Ion Balance
• Arterial Hypertension
• +۳ مورد دیگر

Prof. dr. MS van der Knaap serves as a Visiting Professor at Vrije Universiteit Amsterdam's Faculty of Science within the Integrative Neurophysiology department and Amsterdam Neuroscience - Cellular & Molecular Mechanisms. Her work centers on leukodystrophies and pediatric white matter disorders through advanced neuroimaging and molecular research. Her research spans Leukodystrophy , Leukoencephalopathy , and Magnetic Resonance Imaging applications in neurological diseases, with emphasis on astrocyte pathophysiology and genetic mechanisms. She bridges clinical neurology and molecular neuroscience to develop therapies for rare genetic disorders, particularly focusing on vanishing white matter and megalencephalic leukoencephalopathy. Recent 2025 publications demonstrate translational momentum in gene therapy for leukodystrophies, astrocyte electrophysiology in mouse models, and anesthetic impacts on white matter disorders. These works integrate molecular biology, clinical pediatrics, and neuroimaging to address Metachromatic Leukodystrophy and MLC. Her distinguished recognition includes: Member of the Royal Netherlands Academy of Arts and Sciences (since 2010) She has supervised 27 PhD theses in pediatric neurology and white matter disorders while leading the Foundation for Children with White Matter Disorders (Stichting voor Kinderen met Witte Stof Aandoeningen) as chair since 2011. Her collaborative framework drives clinical-academic partnerships across European research networks. Her current work operates through Amsterdam Neuroscience's Cellular & Molecular Mechanisms division, where interdisciplinary teams investigate leukodystrophy pathophysiology and therapeutic innovation using genetic models and advanced imaging.

• Neuroscience
• Neurology
• Leukodystrophy
• +۳ مورد دیگر

Rajesh Khanna is the Ph.D. Richard And Thelma O.C. Barney Term Professor and Director of the Center for Advanced Pain Therapeutics and Research (CAPToR) at the University of Florida. His primary research focuses on voltage-gated ion channels in chronic pain and neurodegenerative diseases, employing multidisciplinary techniques including mouse genetics, electrophysiology, and behavioral analysis. Key areas include CRMP2 regulation, SUMOylation pathways, and the development of small-molecule therapeutics targeting NaV1.7 and CaV channels. His work bridges basic neuroscience with translational pain management strategies, particularly in osteoarthritis, neuropathic pain, and neurodegenerative disorders like Alzheimer’s. Education: Ph.D. in Pharmacology (not explicitly stated but inferred from title) Research interests emphasize the molecular mechanisms underlying pain chronification, with a focus on ion channel trafficking, glial-neuronal interactions, and neuroinflammation. Recent studies explore CRMP2’s role in mitochondrial dynamics and spinal T lymphocyte regulation, alongside novel analgesics targeting VEGFA and neuropilin-1 pathways. His lab also investigates light-based therapies and CRISPR-mediated gene editing in pain models. Publications from 2025 highlight advancements in CRMP2-Ubc9 inhibitors, conotoxin analgesics, and the role of clock genes in osteoarthritis pain. His work spans preclinical models across rodents, cats, and human-derived neurons, with clinical implications for migraines, fibromyalgia, and NF1-related pain syndromes. Grants and collaborations are implied through his directorship of CAPToR and involvement in porcine models of neurofibromatosis. Future directions include developing CRMP2-based therapies, exploring light therapy applications, and investigating neuroimmune interactions in chronic pain states.

• Chronic Pain
• Neurodegenerative Diseases
• Voltage-Gated Ion Channels
• +۳ مورد دیگر

Dr. Guy Bewick is a Senior Lecturer at the School of Medicine, Medical Sciences and Nutrition, University of Aberdeen. He leads research on neuromuscular junction physiology, mechanosensory systems, and neurological diseases. His work focuses on how nerve terminals adapt signaling for muscle function and disease mechanisms in ALS, muscular dystrophy, and hypertension. He is a Trustee of The Physiological Society (2016–2020). Education: BSc (Hons) Zoology & Animal Physiology – University of East Anglia (1979) PhD Neuroscience – King's College London (1986) FPhysiol – The Physiological Society (2020) Research Interests: Dr. Bewick's lab investigates: Regulation of mechanosensory nerve terminals in muscle spindles Glutamate-mediated autoregulation in sensory endings Motor nerve adaptations to muscle growth/training Therapeutic targets for MND/ALS and muscular dystrophy Recent Publications (Highlights): Studies include calcium regulation in muscle spindles, glutamate receptor roles in mechanosensation, and plant-derived compounds for cancer (2023–2025). Awards: 2016–2020: Trustee, The Physiological Society Grants & Collaborations: Active collaborations with Durham University and others. Supervises PhDs in Biomedical Sciences focusing on ALS and mitochondrial disease impacts on motor control. Labs/Teams: Developing lab-on-a-chip models for ALS research and studying proprioceptive systems in skeletal biology.

• Neuroscience
• Physiology
• Neuromuscular Junctions
• +۵ مورد دیگر

Oliver Seifert is a Senior Associate Professor at Linköping University, affiliated with the Department of Biomedical and Clinical Sciences (BKV) and the Division of Cell and Neurobiology (CNB). His research focuses on dermatological conditions such as lichen sclerosus, psoriasis, and their epidemiological, immunological, and genetic underpinnings. He has contributed to studies on disease incidence, comorbidity patterns, and quality-of-life impacts, leveraging nationwide register data and molecular approaches. Key areas: Cutaneous disorders, epidemiology, immunology, and neurobiology. Recent work includes analyzing lichen sclerosus regional variations and psoriasis severity linked to genetic factors. His division, CNB, investigates cell biology and neurobiology, fostering interdisciplinary research. Notable collaborations include studies on chronic pain mechanisms, ion channel dysfunction in epilepsy, and nano-material applications in medical devices.

• Dermatology
• Immunology
• Neurobiology
• +۴ مورد دیگر

Associate Professor Daniel Poole is affiliated with Monash University's Faculty of Pharmacy and Pharmaceutical Sciences, where he holds a position in the Drug Discovery Biology Theme at the Monash Institute of Pharmaceutical Sciences. He co-directs the Integrated Neurogenic Mechanisms Laboratory and serves as Vice President of the Australasian Society for Autonomic Neuroscience (ASAN) and Secretary of the Society for Neuroscience (SFN) Melbourne Chapter. His research focuses on enteric neurobiology, gastrointestinal physiology, and neuroimmune interactions, particularly in diseases like Hirschsprung Disease and chronic pain mechanisms. He explores opioid receptors and GPCRs in the enteric nervous system to develop therapies for motility disorders and pain. Research interests span defining gut cellular environments, GPCR signaling, and endosomal mechanisms of pain relief. Notable projects include investigating endogenous opioids for treating motility disorders, imaging mouse models of dystrophic epidermolysis bullosa, and characterizing Hirschsprung Disease pathophysiology. His work contributes to UN Sustainable Development Goals through advancements in healthcare and innovation. Publications emphasize endosomal opioid receptor signaling, TRPV4 channel roles, and nanomedicine approaches for pain relief. He leads multiple research initiatives funded by organizations like the Histochemical Society Inc. and collaborates internationally on gastrointestinal and neuroimmune studies. Current activities include supervising PhD students, editing the American Journal of Physiology-Gastrointestinal Liver Physiology, and advancing lab-based projects in neurogenic mechanisms and regenerative therapies.

• Enteric Neurobiology
• Gastrointestinal Physiology
• Neuroimmune Interactions
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Camilla Bellone is an Associate Professor in the Department of Basic Neuroscience at the University of Geneva's Faculty of Medicine. She serves as Vice-Dean for Basic Research and Technology and coordinates the Synapsy Centre for Neuroscience Research in Mental Health. Her research examines synaptic mechanisms underlying addiction and social behavior deficits in autism spectrum disorders through molecular and systems neuroscience approaches. Education includes: Master's in Pharmacy, University of Milan PhD, University of Milan Postdoctoral fellowship, University of San Francisco Dr. Bellone's research investigates synaptic plasticity in reward pathways induced by addictive substances, and neural determinants of social behavior in autism. She employs advanced techniques including optogenetics, electrophysiology, and machine learning to study neuronal circuits in the ventral tegmental area, superior colliculus, and olfactory tubercle. Current work focuses on translating findings into therapeutic strategies for neurodevelopmental disorders. Her recent publications (2022-2025) demonstrate strong focus on: neural circuitry of social behavior, autism pathophysiology, dopamine signaling, optogenetic tools, and machine learning approaches for behavioral analysis. Predominant themes include synaptic plasticity mechanisms, reward processing, threat assessment, and translational models bridging basic neuroscience with clinical applications. Scientific Awards: ERC Consolidator Grant (2019) SNSF Professorship Grant (2014) SNSF Ambizione Fellowship (2011) Dr. Bellone established her laboratory at University of Lausanne through SNSF funding before returning to Geneva. She leads research teams investigating addiction neurobiology and autism-related circuits at the Synapsy Centre. Current projects examine oxytocin's role in neuroinflammation, dopamine regulation of threat salience, and computational analysis of social behavior. As Vice-Dean, she oversees basic research initiatives and technology development within the Faculty of Medicine. Her laboratory collaborates extensively within the Synapsy Centre to advance neuroscience research in mental health disorders.

• Neuroscience
• Synaptic Plasticity
• Addiction Mechanisms
• +۳ مورد دیگر

Weng-Onn Lui is a Professor in Experimental Oncology at Karolinska Institutet's Department of Oncology-Pathology. His research focuses on small RNA biology, particularly microRNAs' roles in cancer development, drug resistance, and viral oncogenesis. He leads the 'Small RNAs in cancer development' research group, part of the Medical Genetics division under Catharina Larsson's group. Education: PhD in Medical Genetics (Karolinska Institutet, 2002), BSc in Applied Science (Tunku Abdul Rahman College, Malaysia, 1996). Postdoctoral training at Stanford University (2004-2008) under Andrew Fire, and earlier postdoc experience in Molecular Medicine at Karolinska (2002-2004). Previous academic roles include Associate Professor (2014-2024), Senior Lecturer (2016-2024), and Swedish Research Council fellowships (2008-2016). Key research areas include molecular mechanisms of Merkel cell carcinoma (MCC), miRNA regulation in drug resistance (e.g., BRAF inhibitors, imatinib), and Dicer enzyme dysfunction in cancer. His work bridges in vitro and in vivo models to explore miRNA-driven tumor progression and therapy response. Notable awards include AACR-Ortho Biotech Scholar awards (2003, 2005-2006), the Stanford Comprehensive Cancer Center Translational Research Award (2007), and Swedish Research Council fellowships. Current grants include funding from the Swedish Cancer Society and Karolinska Institutet. Advisory roles: Supervised PhD students Hannah Björn Andtback (2022) and Yaije Yang (2021). Active collaborations include teams at Fudan University (China), U Mass Medical School (USA), and Ludwig-Maximilians-University Munich (Germany). His lab investigates viral-driven cancer pathways, miRNA biomarkers, and therapeutic resistance mechanisms. Laboratory affiliations: Based at Karolinska University Hospital-Solna (BioClinicum J6:20) with cross-disciplinary ties to the Catharina Larsson group. Research outputs span over 100 peer-reviewed articles in journals like Autophagy , Cancer Research , and Developmental Cell .

• Cancer and Oncology
• Cell and Molecular Biology
• Medical Genetics and Genomics
• +۳ مورد دیگر

Dr Gaetan Burgio is a Group Leader and Head of the Transgenesis Facility at the John Curtin School of Medical Research (JCSMR) at The Australian National University. His research focuses on host-pathogen interactions, antimicrobial resistance, and malaria. He leads the Australian Phenomics Facility's transgenesis core and employs CRISPR/Cas9 genome editing to study bacterial and parasitic pathogens. His academic background includes a medical degree from Paris VII University, a PhD from the Pasteur Institute, and postdoctoral research at Menzies Research Institute and Macquarie University. Key research themes include CRISPR system diversity, host responses to drug-resistant bacteria like Acinetobacter baumannii , and malaria parasite mechanisms. His work is supported by NHMRC and NCRIS grants. He has supervised research students and contributed to over 70 publications on topics ranging from inflammasome biology to RNA modifications. Educations: MSc (Paris XI), MBBS (Paris VII), MD (Paris VII), PhD (Pasteur Institute) Research Interests: Theme 1: CRISPR systems and adaptive immunity mechanisms Theme 2: Host-pathogen interactions in multidrug-resistant bacteria Theme 3: Malaria parasite resistance mechanisms Recent articles highlight advancements in CRISPR applications, interferon signaling against superbugs, and RNA modification analysis. His lab collaborates widely, focusing on translational research to combat emerging infectious diseases.

• Host-Pathogen Interactions
• CRISPR/Cas9 Genome Editing
• Antimicrobial Resistance
• +۵ مورد دیگر

Steven Andrew Barnes is a Professor-in-Residence at the University of California Los Angeles , affiliated with both the David Geffen School of Medicine and the departments of Ophthalmology and Neurobiology . His research focuses on Neurobiology , Neuroscience , and Molecular Physiology , with a strong emphasis on retinal function and cellular mechanisms. Education : BA & PhD in Neurobiology from UC Berkeley (1985) Research Interests : Barnes specializes in retinal neuroscience, investigating calcium signaling, neurotransmitter dynamics (e.g., GABA and dopamine), and ion channel modulation in photoreceptors and ganglion cells. His work bridges cellular neuroscience and ophthalmology , addressing mechanisms of visual processing and retinal disorders. Publications Trends : Recent studies highlight his contributions to understanding mitochondrial dysfunction in Leber's hereditary optic neuropathy , reactive oxygen species in retinal signaling , and transcriptomic analyses of retinal development . His work frequently employs electron microscopy , calcium imaging , and genetic manipulation techniques.

• Neurobiology
• Neuroscience
• Ophthalmology
• +۳ مورد دیگر