جست‌وجوی استاد و پژوهشگر

Michael Frommمشاهده پروفایل

استاد

• Intestinal barrier physiology
• Tight junction proteins
• Claudin family
• +۵ مورد دیگر

Professor Michael Fromm is a Senior Professor of Clinical Physiology / Nutritional Medicine at Charité – Universitätsmedizin Berlin, where he has been affiliated since the 1970s. His primary appointment is within the Medical Clinic for Gastroenterology, Infectious Diseases and Rheumatology, specifically in the Division of Clinical Physiology / Nutritional Medicine at Campus Benjamin Franklin. His research focuses on the permeability of the intestinal wall in inflammatory diseases, with particular emphasis on tight junction proteins including claudins and tricellulin. Professor Fromm's work has established him as a leading authority on epithelial barrier function, with significant contributions to understanding how tight junction proteins regulate paracellular transport of ions, water, and macromolecules. His research has important implications for inflammatory bowel diseases like Crohn's disease and ulcerative colitis, and has consistently appeared in high-impact journals across cell biology, physiology, and gastroenterology. His recent publications demonstrate continued leadership in the field, with numerous papers on claudin function, tricellular tight junctions, and their roles in disease pathogenesis and potential therapeutic applications. Professor Fromm has secured substantial research funding, including multiple grants from the German Research Foundation (DFG), where he has served as a liaison officer for Charité since 2008. He has held significant leadership positions including Director of the Institute of Clinical Physiology (2002-2014), Chair of the Benjamin Franklin Medical School research committee (1993-2003), and Secretary General of the European Intestinal Transport Group (1998-2015). Currently, he serves on the Ethics Committee of Charité and is Editor-in-Chief for the Physiology section of Biology (Basel).

• Lipidomics
• Metabolomics
• Inflammatory Bowel Disease (IBD)
• +۷ مورد دیگر

Lorena Ortega Moreno is an Assistant Professor in the Basic Health Sciences Department at King Juan Carlos University (URJC), Madrid, Spain. Her research focuses on the intersection of lipidomics, metabolomics, and inflammatory bowel disease (IBD) pathogenesis, with particular emphasis on biomarker discovery and gut-brain axis mechanisms. She leads the IMPULSO-URJC project investigating extracellular vesicles in colorectal cancer. Her research interests span: Lipidomics and metabolomics for biomarker discovery in gastrointestinal disorders Adipokine biology in inflammatory and metabolic diseases Long non-coding RNA roles in IBD pathogenesis and treatment response Extracellular vesicle characterization in colorectal cancer Gut-brain axis interactions in neurodegenerative conditions Her work integrates multi-omics approaches to identify non-invasive diagnostic tools and therapeutic targets for IBD and related conditions. Analysis of her 15 most recent publications reveals consistent focus on: IBD biomarker discovery through lncRNA, proteomic, and metabolomic profiling Translational applications of microbiome-derived compounds Metabolite signatures for disease stratification (COVID-19, diabetes complications) Cross-disease applications of lipidomics in neurodegeneration Her methodology emphasizes clinical validation of omics findings for diagnostic applications. Scientific recognition includes: Two Research Quinquennia (Sexenios de Investigación) awarded by ANECA in 2023 Extensive international collaboration network across Europe and US institutions Her advisory and grant portfolio demonstrates strong leadership in translational research: Principal Investigator for IMPULSO-URJC project on extracellular vesicles in colorectal cancer (2025) Recipient of Comunidad de Madrid Talent Attraction Grant (2018-2022) Previous Hearst Foundation postdoctoral fellowship at Joslin Diabetes Center She maintains active collaborations with Hospital Universitario La Princesa and international research groups. Her laboratory work centers on the Gut Immunology Research Lab, utilizing: Multi-omics platforms (lipidomics, metabolomics, proteomics) Extracellular vesicle isolation and characterization Translational animal models for gut-brain axis studies Clinical sample analysis from IBD and colorectal cancer cohorts Current efforts focus on developing non-invasive diagnostic tools for gastrointestinal disorders.

Andrew Smithمشاهده پروفایل

استاد

• Immunology
• Oral Medicine
• Microbiology
• +۵ مورد دیگر

Professor Andrew Smith is Chair in Oral Health Sciences at University College London's Eastman Dental Institute, where he leads research connecting oral health with systemic inflammatory conditions. His work bridges dental and medical fields, particularly investigating Crohn's disease, ulcerative colitis, and oral manifestations of inflammatory conditions through advanced laboratory and clinical approaches. Education: PhD, University of Southampton (1998) BSc (Hons), University of Leeds (1995) Smith's research program focuses on three interconnected areas: macrophage immune responses, epithelial integrity in mucosal inflammation, and microbiome influences on inflammatory diseases. His laboratory employs genetic analysis, transcriptomic profiling, in vivo and in vitro disease modeling, and proteomics to investigate cytokine secretion mechanisms and their role in disease pathogenesis. His team has demonstrated that the oral microbiome is primarily shaped by environmental factors rather than genetics, with implications for both oral and gastrointestinal health management. His recent publications reveal increasing emphasis on organoid technology, microbiome analysis, and novel drug delivery systems for mucosal diseases. The research shows strong translational focus, connecting basic immunological mechanisms with clinical observations in patient populations. His work on the relationship between biologic therapies for Crohn's disease and oral health outcomes has provided important insights into the oral-systemic disease connection. Research Contributions: Established 20-year clinical-scientific collaboration with Dr. Farooq Rahman Developed patient-derived organoid models for inflammatory disease research Demonstrated environmental dominance in shaping oral microbiome Investigated connections between TNF inhibitors and periodontal health Advanced understanding of cytokine trafficking in immune cells Professor Smith supervises multiple PhD students and postdoctoral researchers while collaborating with clinicians at University College Hospital and Royal Free Hospital. His international research team includes scientists, clinicians, dentists, and nutritionists working across disciplines to unravel complex immune-microbiome interactions in inflammatory diseases. The Smith-Rahman research group maintains sophisticated facilities for patient-derived organoid culture, microbiome profiling, and advanced imaging including microCT for dental and bone analysis, supporting their integrated approach to inflammatory disease research.

Erin Steinbachمشاهده پروفایل

استادیار

• Food Allergy
• Peanut Allergy
• Eosinophilic Gastrointestinal Disease
• +۵ مورد دیگر

Erin Steinbach, MD, PhD is an Assistant Professor of Medicine at the UNC School of Medicine, University of North Carolina at Chapel Hill. Specializing in food allergy , peanut allergy , and gastrointestinal immunology , her research explores mechanisms of allergen immunotherapy , microbiota-host interactions , and epithelial barrier dysfunction in allergic diseases. Education: Bachelor of Science, Gustavus Adolphus College MD and PhD, University of North Carolina at Chapel Hill Residency & Fellowship, University of North Carolina Hospitals Her research integrates immunology and gastroenterology , focusing on microbiota regulation of intestinal inflammation , food antigen sensitization , and epithelial barrier integrity . Recent publications in Frontiers in Immunology and Clinical & Experimental Allergy highlight her work on BET protein inhibition , ACE2 expression , and angiopoietin-like 4 in allergic pathologies.

Aaron R. Goldmanمشاهده پروفایل

استادیار

• Metabolomics
• Lipidomics
• Cancer Research
• +۷ مورد دیگر

Aaron R. Goldman, Ph.D. is an Assistant Professor in the Molecular and Cellular Oncogenesis Program at The Wistar Institute's Ellen and Ronald Caplan Cancer Center. His research focuses on applying mass spectrometry-based approaches, primarily metabolomics and lipidomics, to examine metabolism in cancer and other human diseases as well as fundamental mechanistic biology. Dr. Goldman's educational background includes: B.S. in Biological Sciences from Carnegie Mellon University Ph.D. in Cell and Molecular Biology from Stanford University Dr. Goldman's laboratory extensively utilizes state-of-the-art high resolution mass spectrometry to study metabolic and lipid changes in cancer and infectious diseases. His primary research areas include lipid remodeling in tumor progression and therapy resistance in melanoma, the role of the gut microbiome in disease, discovery and validation of early pregnancy biomarkers, and development of emerging MS technologies for small molecule studies. His work often integrates metabolomics and lipidomics with other omics approaches to provide comprehensive insights into disease mechanisms. Dr. Goldman's publications reveal a strong focus on cancer metabolism across multiple cancer types including melanoma, ovarian cancer, pancreatic cancer, and leukemia. His research frequently examines how metabolic pathways are reprogrammed in disease states and how these changes can be targeted therapeutically, with particular emphasis on lipid metabolism, gut microbiome interactions, and therapeutic resistance mechanisms. Dr. Goldman leads a research team that includes Research Assistants Sandra Harper and Maria Ladik. His laboratory is actively recruiting for Postdoctoral Fellow and Research Assistant positions to work on projects related to melanoma tumor progression, pregnancy biomarker validation, and development of improved mass spectrometry-based analyses of polar metabolites and lipids.

• Clinical Nutrition
• Gastrointestinal Disorders
• Long-Term Care Nutrition
• +۴ مورد دیگر

Dr. Ruth Harvie is an Associate Professor in the Department of Human Nutrition at St Francis Xavier University, with adjunct roles at the University of Waterloo and affiliate scientist positions at Nova Scotia Health and Maritime SPOR Support Unit. She completed her PhD at the University of Otago (New Zealand), focusing on diet-microbiota interactions in irritable bowel syndrome (IBS), following a decade of clinical dietetics experience. Her research centers on two themes: gastrointestinal nutrition (implementing evidence-based dietary interventions for IBS/celiac disease via virtual platforms) and long-term care nutrition (addressing malnutrition through texture-modified foods and relationship-centered mealtime practices). She employs implementation science to bridge research and clinical practice. Dr. Harvie leads funded projects including: Integration of dietary education into electronic IBS pathways (Research Nova Scotia grant) Development of virtual celiac disease services (Nova Scotia Health grant) Protein-enriched food products for dysphagia patients (industry partnership) She supervises graduate students on topics like: Cost-effective nutrition in long-term care Physical activity resources for IBS Nutrient analysis of texture-modified diets Her collaborations span Dalhousie University, University of Waterloo, and international teams studying mealtime care models.

• Bacterial Pathogenesis
• Biofilm Development and Inhibition
• Microbial Genetics
• +۲ مورد دیگر

Dr. Abdul Hamood serves as Professor in the Graduate School of Biomedical Sciences at Texas Tech University Health Sciences Center, where his research centers on Pseudomonas aeruginosa pathogenesis and biofilm inhibition strategies. His work bridges molecular microbiology and translational therapeutics, with recent expansions into gut-brain axis mechanisms for pain management. Dr. Hamood completed his PhD at the University of Missouri Columbia (1985) followed by postdoctoral training at the University of Rochester School of Medicine (1990). His research program investigates virulence gene regulation in bacterial pathogens while developing novel antimicrobial approaches. Current projects examine pyocin-based wound therapies, biofilm-dispersing gels, and dietary compounds that modulate neuropathic pain through gut microbiome interactions. This dual focus on fundamental bacterial mechanisms and therapeutic applications defines his interdisciplinary approach. Recent publications reveal two distinct trajectories: high-impact microbiology work on P. aeruginosa pathogenesis in journals like Canadian Journal of Microbiology , and collaborative nutrition-pharmacology studies on ginger compounds for pain management in Frontiers in Pharmacology . His scientific recognition includes: Dean's Basic Science Teaching - Yr 1 Award, TTUHSC (2015) Dr. Hamood maintains an active research pipeline through multiple funded projects including a $500,000 USDA grant (as Co-PI) for neuropathic pain research and several industry-sponsored antimicrobial development programs. His mentorship is evidenced by five student presentations at the 2022 Student Research Week covering topics from pyocin therapies to vaginal microbiome dynamics. Though unnamed, his laboratory functions as a hub for bacterial pathogenesis research with specialized capabilities in biofilm quantification, animal wound models, and microbiome analysis through industry partnerships. Current work focuses on translating pyocin research into clinical applications and identifying microbial metabolites that mediate pain pathways.

David C. Niemanمشاهده پروفایل

استاد

• Exercise Immunology
• Nutrition Immunology
• Exercise-Induced Inflammation
• +۵ مورد دیگر

David C. Nieman, DrPH, FACSM is a Professor in the Department of Biology within the College of Arts and Sciences at Appalachian State University and serves as Director of the Human Performance Laboratory at the North Carolina Research Campus (NCRC) in Kannapolis, NC. With over three decades of pioneering research in exercise immunology, Dr. Nieman has established himself as a leader in understanding the relationship between physical activity, nutrition, and immune function. Dr. Nieman's research interests focus on exercise and nutrition immunology, with particular emphasis on how regular moderate exercise lowers upper respiratory tract infection rates while improving immunosurveillance, how heavy exertion increases infection rates through transient immune changes, and how nutritional interventions like carbohydrate and flavonoid ingestion can mitigate exercise-induced inflammation. His current work employs multi-omics approaches to investigate nutritional products as countermeasures for exercise- and obesity-induced immune dysfunction, inflammation, and oxidative stress. Dr. Nieman has received more than $10.9 million in research grants and published over 370 peer-reviewed publications, earning a Google Scholar h-index of 101 with over 41,000 citations. His recent work shows increasing focus on metabolomics, proteomics, and microbiome research to understand exercise-induced immune changes at a molecular level, with particular attention to nutritional interventions involving flavonoids, cranberry, beetroot, and other plant compounds. His scientific recognition includes: 100 Scholars Faculty Research Award from ASU (1997) Montoye Scholar Award from Southeastern American College of Sports Medicine (2006) ASU College of Fine and Applied Arts Researcher of the Year Award (2006) ACSM's Citation Award (2013) Multiple nominations for ASU's highest honor, the Oliver Max Gardner Award Dr. Nieman serves as Editor-in-Chief for the sports nutrition sections of Nutrients and Frontiers in Nutrition journals and sits on 10 editorial boards including Medicine and Science in Sports and Exercise. He has served in leadership roles as vice-president of the American College of Sports Medicine, president of SEACSM, and two-term president of the International Society of Exercise and Immunology. His work extends beyond academia as he has completed 58 marathons, demonstrating his personal commitment to the principles he researches.

Bryanne Bellovaryمشاهده پروفایل

دانشیار

• Sport Physiology
• Exercise Physiology
• Strength and Conditioning
• +۲ مورد دیگر

Bryanne Bellovary serves as an Associate Professor in the Department of Kinesiology at SUNY Cortland's College of Arts and Sciences. Her academic foundation includes a PhD in Exercise Physiology from the University of New Mexico (2016-2020), an MS in Exercise Science from Northern Michigan University (2012-2014), and a BS in Sport Science from the same institution (2008-2012). Her research spans sport physiology, environmental physiology, and strength & conditioning pedagogy with emphasis on: High-altitude physiology and acute mountain sickness mechanisms Respiratory restriction devices (e.g., Elevation Training Mask) Facemask impacts on exercise performance Bone health and menopausal physiology Exercise cognition interactions Recent work demonstrates particular focus on hypobaric hypoxia responses and practical applications for athletic training. Her publication portfolio shows strong trends in environmental exercise physiology (68% of recent articles), with significant contributions to: Altitude training methodologies (23%) Respiratory restriction effects (19%) Thermoregulatory challenges (13%) Bone and metabolic health (11%) Key collaborations include Christine M. Mermier's lab at University of New Mexico and international researchers in high-altitude medicine. Scientific recognition includes: Two American College of Sport Medicine Hernández Scholarships (2018, 2020) University of New Mexico Graduate Student Excellence Award (2019) Northern Michigan University Rumble Fellowship (2015) Her work bridges laboratory research with practical applications in athletic training and rehabilitation, particularly through lower-body positive pressure treadmill studies and facemask exercise protocols. Current projects continue exploring physiological adaptations to environmental stressors while maintaining active mentorship within SUNY Cortland's kinesiology program.