جست‌وجوی استاد و پژوهشگر

Jianmin Suمشاهده پروفایل

عضو هیئت علمی

• Synapse Formation
• Neuroscience
• Molecular Neuroscience
• +۵ مورد دیگر

Jianmin Su, Ph.D., is a Research Assistant Professor at the Fralin Biomedical Research Institute at Virginia Tech Carilion (VTC), affiliated with the Weston Lab. His research is focused on the cellular and molecular mechanisms underlying synapse formation, including synaptic targeting, differentiation, and maturation. He is actively involved in neuroscience research with a strong emphasis on synaptic organization and neural circuit development. Education: Ph.D. in Medicine, Fudan University Postdoctoral Fellowship, Virginia Commonwealth University, Medical School/Anatomy Dr. Su's research interests center on synaptic development, particularly the role of extracellular matrix proteins, transmembrane collagens, and signaling molecules such as Reelin and fibroblast growth factors in neural connectivity. His work integrates molecular biology, neuroanatomy, and developmental neuroscience to understand how precise synaptic circuits are established in the brain. His recent publications highlight a consistent focus on synaptic assembly in various brain regions, including the cerebellum, hippocampus, and visual system. Key themes include the role of matricryptins, integrin signaling, and region-specific expression of structural proteins in synaptogenesis. His work often involves mouse models and detailed molecular analysis. Dr. Su has collaborated extensively with Dr. Michael A. Fox and other researchers, contributing to high-impact journals such as Journal of Neuroscience , Cell Reports , and Frontiers journals. While no scientific awards are listed, his publication record demonstrates sustained scholarly output in molecular neuroscience. He advises no listed students, but his role as a research faculty suggests involvement in mentoring junior researchers and lab personnel. His work is supported through institutional affiliations and likely grant funding, though specific grants are not mentioned. Dr. Su is based in the Weston Lab, which focuses on neural development and synaptic function, contributing to a collaborative and interdisciplinary research environment.

• Cancer Biology
• Hematology
• Developmental Genetics
• +۵ مورد دیگر

Martin H. Distel is a researcher affiliated with the Department of Pediatrics and the Hematology/Oncology Division . His work spans cancer biology, developmental genetics, and advanced imaging techniques in zebrafish models. PhD in Developmental Genetics, Technical University of Munich Postdoctoral Fellow, University of California, San Diego MSc and BSc, Technical University of Munich His research focuses on leveraging zebrafish models to study cancer mechanisms, including Ewing sarcoma and melanoma, and developing targeted therapies. He also investigates optical imaging technologies and their applications in oncology and neuroscience. Recent publications highlight work on drug screening in zebrafish xenografts, ROS-induced cancer cell targeting, and epigenetic regulation in tumors. His studies frequently employ high-content imaging and molecular biology approaches. Martin Distel contributes to preclinical testing of immunotherapies like CAR T-cells and has explored Notch signaling in hematopoietic stem cell differentiation. His interdisciplinary research bridges genetics, pharmacology, and biomedical engineering.

Kathleen E. Sullivanمشاهده پروفایل

استاد

• Epigenetics of inflammation
• Primary immune deficiencies
• Immunology
• +۳ مورد دیگر

Kathleen E. Sullivan is a Professor of Pediatrics (Allergy/Immunology) at the Perelman School of Medicine, University of Pennsylvania , affiliated with the Children's Hospital of Philadelphia (CHOP) . Her research focuses on the epigenetics of inflammation and primary immune deficiencies , particularly examining enhancer-promoter interactions in systemic lupus erythematosus (SLE) using techniques like ChIP-seq and RNA expression analysis. Research Trends from her publications highlight: (1) epigenetic mechanisms in autoimmune diseases, (2) genetic basis of immune dysregulation, and (3) clinical-genomic correlations in 22q11.2 deletion syndrome. Her work bridges molecular immunology and pediatric clinical immunology . Contact: sullivank@email.chop.edu | Office: 267-426-2836

Caroline Pellet-Manyمشاهده پروفایل

مدرس ارشد

• Cardiovascular Biology
• Cardiac Regeneration
• Atherosclerosis
• +۴ مورد دیگر

Dr. Caroline Pellet-Many serves as a Senior Lecturer in Biomedical Sciences at the Royal Veterinary College (RVC), specializing in Cardiovascular Biology within the Department of Comparative Biomedical Sciences at the Camden campus. She is an active member of the Cardiovascular and Renal Biology research group and CPCS Research Programme, teaching across BVetMed and BSc Biological Sciences degrees while co-directing BSc/MSci programmes. Academic Background: Undergraduate & Maitrise in Biology, Université Louis Pasteur, Strasbourg MSc in Physiology (Distinctions), Birkbeck College PhD in Cardiovascular Biology, University College London (2010) Her research centers on gene regulation and molecular mechanisms in cardiovascular diseases , utilizing in vivo models to investigate smooth muscle cells and macrophages in atherosclerotic plaque formation. She pioneers zebrafish models for cardiac regeneration studies, examining epicardial/endocardial roles and fin regeneration for angiogenesis. Current work focuses on Neuropilins (NRP1/NRP2) in macrophage polarization during heart repair, with implications for therapeutic interventions. Analysis of her 15 most recent publications reveals consistent focus on neuropilin signaling in cardiovascular contexts, particularly cardiac regeneration mechanisms using zebrafish models, atherosclerosis progression, and angiogenesis regulation. Key themes include receptor crosstalk (VEGFR2, PDGFR), cellular migration pathways, and inflammatory modulation in vascular disease. Professional Recognition: Fellow of the Higher Education Academy Dr. Pellet-Many supervises BSc, MSci, and PhD students including Petra Mendes-Vieira's project on neuropilins in zebrafish heart regeneration. She serves on the London Vascular Biology Forum committee and the British Small Animal Veterinary Association grant award committee, while actively promoting cardiovascular health through British Heart Foundation outreach and RVC's 'Night at the Vet College' events. As a core member of RVC's Cardiovascular and Renal Biology group, she integrates zebrafish regeneration models with molecular techniques to investigate therapeutic targets for heart disease, emphasizing translational applications in veterinary and human medicine.

Benjamin Kormanمشاهده پروفایل

دانشیار

• Scleroderma (systemic sclerosis)
• Autoimmune connective tissue diseases
• Fibrosis research
• +۴ مورد دیگر

Benjamin Korman, M.D. is an Associate Professor in the Department of Medicine, Allergy/Immunology and Rheumatology at the University of Rochester School of Medicine and Dentistry. He is a practicing rheumatologist specializing in scleroderma and related autoimmune connective tissue diseases, providing interdisciplinary care for patients with complex manifestations including skin fibrosis, vascular disease, and organ involvement. Dr. Korman's clinical expertise focuses on: Diagnosis and management of scleroderma (systemic sclerosis) Autoimmune connective tissue diseases Interdisciplinary care for skin fibrosis and thickening Vascular disease including Raynaud's phenomenon Gastrointestinal issues related to autoimmune conditions Lung disease including interstitial lung disease and pulmonary hypertension His research program, the Korman Lab, investigates the cellular and molecular mechanisms underlying fibrosis and vascular disease in scleroderma. The lab utilizes experimental models, patient samples, and translational approaches to understand the relationship between adipose cells, blood vessels, and fibroblasts. Current research focuses on: Pulmonary hypertension in scleroderma Skin fibrosis mechanisms The role of TNF signaling in vascular pathology Biomarker discovery for disease severity and progression Novel therapeutic approaches targeting fibrosis pathways Dr. Korman has published extensively on scleroderma, with recent work focusing on TNF-mediated pulmonary hypertension, complement factors as biomarkers, and the role of adipokines in fibrosis. His research has contributed significantly to understanding disease heterogeneity and developing personalized treatment approaches for patients with scleroderma. His scientific contributions include: Development of novel mouse models of scleroderma-associated pulmonary hypertension Identification of biomarkers for scleroderma disease severity Studies on the role of adipose tissue in fibrosis development Investigations into the cellular mechanisms of vascular remodeling Dr. Korman is actively involved in mentoring and training the next generation of rheumatology researchers and clinicians. He leads a multidisciplinary research team investigating the pathogenesis of scleroderma and related conditions, with a focus on translating basic science discoveries into clinical applications for improved patient care.

Lindsay Caseمشاهده پروفایل

استاد

• Cell Biology
• Molecular Biophysics
• Transmembrane Signaling
• +۳ مورد دیگر

Lindsay Case is the Irwin and Helen Sizer Career Development Professor at the Massachusetts Institute of Technology (MIT), located in the Koch Biology Building. Her research focuses on how cells regulate the spatial organization of signaling molecules at the plasma membrane, particularly through mechanisms like phase separation and biomolecular condensates. She employs quantitative approaches from biochemistry, molecular biophysics, and cell biology to study transmembrane signaling pathways and their dysregulation in diseases such as cancer. Education: PhD (2014) in Molecular Biology from the University of North Carolina at Chapel Hill, and BA (2008) in Biology from Franklin and Marshall College. Research Interests: The lab investigates how receptor clustering and protein assemblies create membrane compartments with unique biochemical properties. Key themes include phase separation in signaling pathways, membrane-induced protein phase behavior, and the role of actin dynamics in adhesion and signaling. These studies use reconstituted systems and live-cell imaging to dissect molecular mechanisms. Key Awards: NSF Career Award (2025) Searle Scholar Award (2022) NIH Director’s New Innovator Award (2022) AFOSR Young Investigator Award (2021) Brown-Goldstein Award (2020) Damon Runyon-Dale F. Frey Breakthrough Scientist (2020) Her work bridges fundamental cell biology with disease mechanisms, emphasizing the biophysical and biochemical principles governing membrane-associated signaling processes.

Lydia Sorokinمشاهده پروفایل

استاد

• cell-matrix interactions
• leukocyte extravasation
• blood vessels
• +۴ مورد دیگر

Lydia Sorokin is a Professor at the Institute of Physiological Chemistry and Pathobiochemistry within the University of Münster , Germany. She serves as Spokesperson for the Cells in Motion Interfaculty Centre and actively contributes to the Imaging Network and CiM-IMPRS graduate program . Research Focus: Cell-matrix interactions, leukocyte extravasation, blood vessel biology, secondary lymphoid organs, and neuroinflammatory processes. Key Contributions: Elucidating laminin functions in vascular integrity, neuroinflammatory disease mechanisms, and extracellular matrix regulation of immune cell migration. Publication Trends: Recent studies (2022-2024) explore CNS macrophage heterogeneity , endothelial-laminin interactions , and neurovascular unit dysfunction in diseases like multiple sclerosis and cerebral small vessel disease. Earlier work (2012-2020) established roles for laminins and matrix metalloproteinases in blood-brain barrier regulation, immune cell trafficking, and tissue-specific matrix responses. Collaborations & Networks: Active in Cells in Motion , Imaging Network , and CiM-IMPRS graduate program. Collaborates with institutions across Europe on neurovascular and immunology research. Contact: sorokin@uni-muenster.de

Chi Wangمشاهده پروفایل

استاد

• Cancer Biostatistics
• Bioinformatics
• Survival Analysis
• +۱۰ مورد دیگر

Chi Wang, Ph.D., is Professor of Internal Medicine and Statistics at the University of Kentucky, Associate Director of the Biostatistics & Bioinformatics Shared Resource, and a lead computational scientist within the Markey Cancer Center. With an h-index of 39 and >5,300 citations, he develops cutting-edge survival-analysis and high-dimensional-omics methods that are translated into prostate, breast, lung and neuroblastoma trials. Education: Ph.D. Biostatistics, Johns Hopkins University, 2009 M.S. Statistics, Peking University, 2003 B.S. Mathematics, Peking University, 2001 Research Focus: Wang’s group integrates Bayesian statistics, machine-learning and single-cell sequencing to model tumor evolution, drug resistance and biomarker-driven adaptive trials. Major themes include enzalutamide resistance in prostate cancer, PLK1-mediated immune evasion in lung adenocarcinoma, obesity-adipose drivers of breast cancer, and epigenetic reprogramming of tumor-infiltrating lymphocytes. Recent Article Trends (2023-2025): Fifteen showcased papers reveal a dual trajectory—(1) mechanistic dissection of kinases (PLK1, DDR1, ABL1/2) and metabolic enzymes (FASN, NNMT, HSP47) that orchestrate resistance and metastasis, and (2) probabilistic algorithms for temporal mutation ordering, biomarker evaluation and single-cell deconvolution. Overarching keywords are precision oncology, drug resistance, tumor micro-environment, and computational systems biology. Funding & Awards: He is PI/co-I on 152 grants (32 active) from NCI, ACS, V Foundation, etc., totaling >$30 M direct costs. Highlights include NCI U01 for predictive biomarkers, American Cancer Society award on collagen lysyl hydroxylase metastasis drivers, and NCI R01s targeting NNMT in triple-negative breast cancer and TIL epigenetic reprogramming in NSCLC. Student & Team Mentorship: Wang trains a large multi-disciplinary cohort of Ph.D. students, post-docs and clinical fellows who routinely lead first-author papers and are funded on his grants. His lab sits within the Markey Cancer Center’s Molecular & Cellular Oncology program and the Center for Computational Sciences, fostering daily bench-to-bedside collaboration.

Yuntao Wuمشاهده پروفایل

استاد

• Virology
• HIV Pathogenesis
• Immunology
• +۴ مورد دیگر

Dr. Yuntao Wu is a Professor at George Mason University's School of Systems Biology, where he holds dual appointments as Research Faculty and Instructional Faculty. He is affiliated with the Center for Infectious Disease Research (CIDR) and has dedicated over 30 years to virology research, with the past 20 years focused specifically on HIV infection mechanisms in blood CD4 T cells and macrophages. Dr. Wu received his PhD in Molecular Virology from Queen's University in Kingston, Ontario, Canada in 1998. He completed postdoctoral training at the National Institutes of Health (NIH), where his work on HIV-1 pre-integration transcription in resting CD4 T cells was published in Science in 2001. His laboratory investigates fundamental mechanisms of HIV pathogenesis with particular emphasis on chemokine co-receptor signaling, the role of cofilin in HIV infection, and PSGL-1 as an HIV restriction factor. His research has been published in premier journals including Cell (2008), Science Advances (2019), and Nature Microbiology (2019). A key focus has been understanding how HIV overcomes cortical actin restriction in resting CD4 T cells, which has led to the development of HIV Rev-dependent vectors for targeting viral reservoirs. Dr. Wu's publication record reveals an evolving research trajectory from fundamental HIV entry mechanisms to innovative therapeutic approaches. Early work established the role of actin dynamics in HIV infection, while more recent studies have identified PSGL-1 as a restriction factor and explored natural compounds that inhibit HIV. His laboratory consistently bridges basic science with translational applications, particularly in developing strategies to target and eliminate HIV reservoirs. Dr. Wu actively mentors the next generation of scientists through his vibrant laboratory environment at George Mason University. His lab includes PhD students specializing in various aspects of HIV research, including PSGL-1 restriction, HBV cccDNA targeting, HIV cytoskeleton interactions, natural compounds that inhibit HIV, and Rev-dependent SIV targeting vectors. His research has been supported by multiple grants focused on viral pathogenesis and therapeutic development. The Wu Lab operates as a multidisciplinary research hub equipped with advanced technologies including flow cytometry, RT-PCR, viral vector design and production, fluorescent microscopy, and plasmid cloning. Current projects span HIV reservoir targeting, cofilin pathway modulation, natural compound screening, viral imaging, and hepatitis B virus research. The lab actively recruits George Mason University students as blood donors for ongoing HIV research, demonstrating strong community engagement in the scientific process.

• Cancer Biology
• Chemoprevention
• Cancer Therapeutics
• +۵ مورد دیگر

Sanjay Srivastava, PhD, serves as University Distinguished Professor and Chairperson of the Department of Immunotherapeutics and Biotechnology at Texas Tech University Health Sciences Center (TTUHSC) School of Pharmacy. Holding the James A 'Buddy' Davidson Endowed Professorship in Pharmacology and Oncology, he previously served as Associate Dean for Research (6 years) and Graduate Programs (4 years), establishing TTUHSC's Ph.D. program in Abilene. With over 160 publications and an H-Index of 59, his work bridges academic leadership and cutting-edge cancer research. His educational foundation includes: PhD in Industrial Toxicology Research Center and Kanpur University (1991) MS from Lucknow University (1987) BS from Lucknow University (1985) Certificate (mini MBA) from University of Pittsburgh (2004) Dr. Srivastava's research pioneers drug repurposing strategies targeting STAT-3, NF-kB, and HER2 pathways in pancreatic, ovarian, breast, melanoma, and brain cancers. His laboratory investigates molecular mechanisms of resistance while exploring non-cancer drugs like penfluridol and atovaquone as novel therapeutics. This approach combines molecular toxicology with translational oncology to overcome treatment barriers in aggressive malignancies. Analysis of his 2019-2024 publications reveals dominant trends in immune checkpoint modulation , tumor microenvironment reprogramming , and repurposed antipsychotics/antimalarials for cancer therapy . His work consistently targets drug resistance mechanisms across multiple cancer types, with growing emphasis on immunometabolism and microbiome interactions. Major recognitions include: Election as AAAS Fellow (2023) Stanford's World's Top 2% Scientists (2020, 2021) National Academy of Inventors induction (2018) Chancellor's Distinguished Research Award (2024) As a dedicated mentor, he chairs doctoral advisory committees while securing National Cancer Institute/NIH grants exceeding $5M. His editorial roles span AACR, SOT, and AAPS societies, and he serves on NIH/DoD grant review panels. Current teaching includes Cancer Biology and Therapeutics (GPSC5326). Dr. Srivastava leads a multidisciplinary research team investigating drug resistance mechanisms, with recent work featured in major news outlets for breakthroughs in repurposing milbemycin oxime and proguanil for pancreatic and breast cancers.

David Leeمشاهده پروفایل

استاد

• Mechanobiology
• Tissue Engineering
• Cell Engineering
• +۳ مورد دیگر

David Lee is a Professor of Cell and Tissue Engineering at Queen Mary University of London, serving as Deputy Vice Principal - Impact (Enterprise and Commercial Innovation). He holds a BSc (Hons), MA, and PhD. His primary research focuses on mechanobiology, studying how mechanical forces influence cellular and tissue behavior, particularly in cartilage, stem cells, and circadian biology. His work has led to over 100 refereed papers and significant grant funding, including awards like the Negma Lerads Prize. Lee investigates how mechanical stimuli modulate stem cell differentiation, nuclear architecture, and circadian rhythms, with applications in organ-on-a-chip systems and regenerative medicine. He leads grants totaling over £5 million, including BBSRC, EPSRC, and Wellcome Trust funding. His research group explores musculoskeletal tissues, mechanoregulation of nuclear organization, and integrating circadian biology into in vitro models. Education: BSc (Hons), MA, PhD Affiliations: School of Engineering and Materials Science, Centre for Bioengineering Grants: EPSRC Centre for Doctoral Training in Organ-on-a-Chip Technology (£7M), BBSRC grants on circadian biology integration (£387K), and EPSRC funding for mechanical stimuli studies (£436K) Labs/Teams: Research Group in Mechanobiology and Tissue Engineering, collaborating on organ-on-a-chip development His research highlights include demonstrating mechanical force's role in stem cell differentiation and linking circadian rhythms to mechanobiology for better in vitro models. Lee aims to advance regenerative medicine through engineered tissue systems and mechanistic insights.

• Mathematical Biology
• Dynamical Systems
• Quantitative Developmental Biology
• +۴ مورد دیگر

Roeland Merks is a Professor of Mathematical Biology at Leiden University's Faculty of Science, holding dual appointments in the Mathematical Institute (Analysis and Dynamical Systems group) and the Institute of Biology Leiden (Animal Sciences). His research bridges advanced computational modeling with biological questions, focusing on vascular development, tumor angiogenesis, and quantitative developmental biology. His research interests center on mathematical modeling of biological systems , particularly using agent-based approaches like the Cellular Potts Model to simulate lumen formation, tumor vasculature, and developmental processes. Key areas include computational angiogenesis, vascular network dynamics, endothelial cell behavior, and mathematical oncology. His work integrates dynamical systems theory with biological experimentation to unravel complex morphogenetic processes. Analysis of his recent publications reveals a strong trend toward translational computational biology , with increasing focus on tumor vasculature repair mechanisms, infant gut modeling, and plant sensory systems. His work consistently applies mathematical rigor to biomedical problems, particularly in understanding how physical forces and biochemical signals interact during vascular development. Professor Merks actively mentors doctoral candidates including Tessa Vergroesen and David Mattias Versluis, with former students such as Burak Demirbaş and Lisanne Rens contributing to his research legacy. His laboratory operates at the mathematics-biology interface, developing computational frameworks that generate testable biological hypotheses.

Irene Athanassakisمشاهده پروفایل

استاد

• Immunology
• Molecular Biology
• Cell Biology
• +۳ مورد دیگر

Professor Irene Athanassakis is a faculty member at the Biology Department of the University of Crete. She holds a PhD in Biochemistry, Molecular Biology, Cellular and Developmental Biology from the University of Alberta (1988). Her research focuses on immunology, reproductive biology, and cancer diagnosis, with particular emphasis on MHC molecule regulation, T cell activation, and nonlinear optical imaging techniques. She leads a laboratory in the Biology building (Office: Γ 125, Lab: Ε 130) and has contributed extensively to understanding immune tolerance mechanisms and developing implantable vaccine technologies. Key research areas include soluble MHC antigens' role in immune modulation, diagnostic applications of third/harmonic generation microscopy for cancer grading, and the interplay between L-carnitine and endometriosis. Her work bridges molecular immunology with biomedical engineering, addressing clinical challenges in autoimmune diseases and cancer. Recent research trends highlight her contributions to SARS-CoV-2 immunogenicity studies, implantable vaccine design using laser-structured scaffolds, and machine learning-based analysis of biological samples. These studies underscore her interdisciplinary approach to solving complex biomedical problems. No scientific awards are explicitly listed in the provided materials. She advises no listed PhD/Master’s students but collaborates widely across disciplines. Her lab's activities include developing novel diagnostic tools and immunotherapeutic strategies, reflecting her commitment to translational research.

• Tissue Engineering
• Stem Cell Biology
• Regenerative Medicine
• +۳ مورد دیگر

Associate Professor Giselle Yeo is an academic at the University of Sydney's School of Life and Environmental Sciences. She holds an NHMRC Emerging Leadership Fellowship and a USyd Early Career Development Fellowship. Her research focuses on matrix-induced stem cell biology, regenerative materials, and biomaterial design for tissue engineering. Key areas include tropoelastin's role in cellular longevity, hydrogel mechanics modulation via photochemistry, and mesenchymal stromal cell expansion strategies. Dr Yeo completed her PhD in matrix protein biochemistry at the University of Sydney, followed by postdoctoral research in biofunctionalisation for tissue engineering. She has pioneered studies on extracellular matrix proteins' effects on stem cell behavior and aging mechanisms. Her scientific accolades include the 2023 Young Tall Poppy Award and grants such as 'Dynamic Presentation of Physical Cues to Engineer Aging Models' (2025) and 'Engineering Cellular Longevity' (2024). She leads interdisciplinary projects at the Sydney Nano Institute and Charles Perkins Centre, emphasizing translational research in regenerative medicine. Recent work explores plasma-activated surfaces for bioprinting, cost-effective stem cell expansion platforms, and stress-induced senescence mitigation. Her articles highlight innovations in biomaterials, cellular rejuvenation, and hydrogel technologies.

Anne E Cressمشاهده پروفایل

استاد

• Cancer Biology
• Cell Biology
• Molecular Biology
• +۳ مورد دیگر

Dr. Anne E Cress is a tenured Professor at the University of Arizona College of Medicine in the Departments of Cellular and Molecular Medicine and Radiation Oncology. She is Vice Dean for Strategy and Innovation and a founding faculty member of the UA Cancer Center and Cancer Biology Graduate Program. Her research focuses on cancer invasion and metastasis mechanisms. University of Arizona (PhD in Biochemistry) Stanford University (Postdoc in DNA Replication) University of Queensland (Postdoc in Peptide Chemistry) Netherlands Cancer Institute (Postdoc in Developmental Biology) Research Interests: Dr. Cress investigates molecular mechanisms of human epithelial cancer invasion and metastasis, emphasizing integrin regulation and laminin adhesion structures. Her team developed cyclized peptides, small molecules, and antibodies to block cancer progression and studies heterotypic cancer clusters using gene editing tools. Publication Trends: Recent articles highlight prostate cancer metastasis, biophysical tumor invasion barriers, integrin signaling in epithelial-mesenchymal cooperation, and laminin-targeted therapeutic strategies. Studies integrate molecular biology with biophysical modeling to address drug resistance and actionable pathways in cancer clusters.