جست‌وجوی استاد و پژوهشگر

Joëlle Sobczak & Mathieu Boissanمشاهده پروفایل

عضو هیئت علمی

• TGF-β signaling
• Cellular plasticity
• Cancer biology
• +۷ مورد دیگر

Joëlle Sobczak and Mathieu Boissan are co-leaders of a research team at Sorbonne University in partnership with Inserm, based at Saint-Antoine Hospital in Paris. Sobczak holds the position of Professor (PU) while Boissan serves as a University Lecturer-Hospital Practitioner (MCU-PH). They jointly lead Equipe 3, which focuses on metastatic dissemination, epithelial-mesenchymal transition, cell senescence, invasion, and chemoresistance in cancer biology. Their research investigates the dual role of TGF-β signaling in cancer progression, from early tumor suppression to late-stage metastatic promotion. Their research interests center on TGF-β signaling in cellular plasticity and cancer, with specific focus on nucleoside diphosphate kinases in metastasis, KIF20A kinesin in tumor progression, and metal-based anti-tumor drugs. They study how cellular processes like epithelial-mesenchymal transition, senescence, and invasion contribute to cancer aggressiveness and chemoresistance. Their work bridges fundamental molecular mechanisms with potential therapeutic applications, particularly in understanding how TGF-β signaling can be targeted to prevent metastasis. Analysis of their recent publications reveals a strong focus on cancer cell signaling mechanisms, particularly TGF-β pathways and their role in metastasis. Their work spans molecular biology, cell signaling, and cancer pharmacology, with increasing emphasis on therapeutic development in recent years. Key research themes include ubiquitin ligases in TGF-β signaling, nucleoside diphosphate kinases as metastasis suppressors, and novel metal-based anti-cancer compounds that overcome chemoresistance. As team leaders, they supervise multiple PhD students and postdoctoral researchers including J. Selot, S. Amhaz, and C. Monraz. Their laboratory is part of a larger collaborative structure at Saint-Antoine Hospital that includes three specialized teams investigating different aspects of TGF-β signaling in cancer. The team benefits from collaborations with chemists at IPCM, Paris, for developing novel metallodrugs, and maintains strong connections with both basic science and clinical researchers. Their laboratory is housed at Saint-Antoine Hospital in the Kourilsky Building at 184, rue du Faubourg Saint-Antoine, 75012 Paris, France. The team operates within a multidisciplinary environment that includes molecular biologists, clinicians, and biochemists working collaboratively on cancer research. They are part of Sorbonne University's research ecosystem with strong ties to Inserm, facilitating both fundamental research and potential clinical translation of their findings.

Homaira Rahimiمشاهده پروفایل

دانشیار

• Pediatric Rheumatology
• Autoimmune Diseases
• Inflammatory Disorders
• +۳ مورد دیگر

Homaira Rahimi, M.D., is an Associate Professor at the University of Rochester's Department of Pediatrics, specializing in Pediatric Rheumatology. She holds dual expertise in Pediatrics and Pediatric Rheumatology, certified by the American Board of Pediatrics. Research focuses on juvenile idiopathic arthritis (JIA), inflammatory myopathies, systemic lupus erythematosus (SLE), and mixed connective tissue disease Investigates lymphatic dysfunction as a contributor to arthritis flares, particularly through imaging studies of lymph nodes and molecular targets like sGC beta1 Key affiliations include the University of Rochester Medical Faculty Group (URMFG) and Accountable Health Partners (AHP) Her publications span topics in rheumatology imaging, biomarker validation, and autoimmune disease mechanisms, with recent work on lymphatic pulse regulation and arthritic flare pathways. Awards include multiple travel grants and the Medicine/Pediatrics Leadership Award.

Gerrit Wolters-Eisfeldمشاهده پروفایل

پژوهشگر ارشد

• Glycobiology
• Cancer Research
• O-glycosylation
• +۴ مورد دیگر

Gerrit Wolters-Eisfeld is a Research Fellow at the University of Hamburg within the Faculty of Medicine and the Department of General, Visceral and Thoracic Surgery . His work focuses on glycobiology and O-glycosylation tumor antigen expression integrin/selectin signaling pancreatic cancer pathogenesis cell adhesion mechanisms molecular diagnostics . His recent publications (2024-2015) explore glycan-mediated signaling in esophageal , pancreatic , and ovarian cancer , with applications in prognostic biomarkers , immune microenvironment analysis, and targeted therapy development. Articles highlight dysregulated glycosylation patterns (Tn/STn antigens) as drivers of cancer progression and potential therapeutic targets. Key collaborations include work with Prof. Claus Wagener , Prof. Jakob Izbicki , and Prof. Martin Bockhorn . Research spans from genetic models to clinical biomarker validation , with cross-functional studies involving immunology , oncology , and biochemical pathways .

• Anesthesiology
• Intensive Care Medicine
• Stem Cell Therapy
• +۴ مورد دیگر

Martin Stenlo is a Specialist Physician and Researcher in Anesthesiology and Intensive Care at Lund University's School of Medicine, affiliated with StemTherapy: National Initiative on Stem Cells for Regenerative Therapy. His work focuses on lung injury models, stem cell applications, and transplantation outcomes. Research interests include acute respiratory distress syndrome (ARDS) lung transplantation mesenchymal stem cell therapy proteomic analysis of graft dysfunction fluorescence imaging techniques regenerative medicine approaches Recent publications highlight his contributions to expanding donor lung pools, reducing inflammation via stem cells, and developing novel imaging tools for lung injury assessment. Key collaborations center on translational studies in porcine models and clinical trials.

Maja Herak Bosnarمشاهده پروفایل

دانشیار

• Molecular Biology
• Cancer Research
• Metastasis Suppression
• +۵ مورد دیگر

Maja Herak Bosnar is a distinguished Associate Professor and scientific advisor at the Ruđer Bošković Institute, where she serves as a Member of the Board of Governors and works within the Division of Molecular Medicine, Laboratory for protein dynamics. She holds academic appointments at University Josip Juraj Strossmayer Osijek and University in Dubrovnik, where she teaches doctoral courses in Molecular Basis of Metastasis Formation and Cancer Genetics and Tumor Cell Biology. Her educational background includes B.Sc. (1993), M.Sc. (1996), and Ph.D. (2002) in molecular biology from the Faculty of Sciences and Mathematics, University of Zagreb. Her research spans molecular biology, cancer research, and metastasis suppression, with a particular focus on NME/Nm23/NDPK proteins and their role in cancer progression. Her publication record demonstrates a consistent research trajectory examining the evolutionary conservation of cancer-related genes, with particular emphasis on mitochondrial NME6 protein function. Her recent work (2022-2024) shows increasing focus on mitochondrial dynamics in tumor cells, resistance mechanisms in melanoma, and the evolutionary conservation of metastasis suppressors across diverse organisms from sponges to humans. Her research integrates molecular biology, evolutionary perspectives, and clinical oncology to understand fundamental cancer mechanisms. Annual reward of the Ruđer Bošković Institute for scientific publication (2020) Annual reward of the Ruđer Bošković Institute for scientific publication (2018) Annual reward 'Josip Juraj Strossmayer' for the best scientific publication (2007) Dr. Herak Bosnar has supervised numerous doctoral and master's theses, mentoring researchers who have investigated topics ranging from nm23-H1 gene function in cell adhesion to resistance mechanisms in melanoma. She has led multiple significant research projects including the Croatian Scientific Foundation project 'Structure, function and evolution of Nme6/Nm23-H6 gene/protein' and French-Croatian bilateral projects on mitochondrial NME proteins. She serves on the Oversight Committee of the Croatian Association for Cancer Research and the Executive Committee of the Croatian Society of Biochemistry and Molecular Biology. She leads research in the Laboratory for protein dynamics at the Ruđer Bošković Institute, where her team investigates protein localization, mitochondrial dynamics, and evolutionary conservation of cancer-related pathways using diverse model systems from human cell lines to sponge models.

Juncheng Weiمشاهده پروفایل

استادیار

• Lipid metabolism
• Glucose metabolism
• Metabolic disease
• +۵ مورد دیگر

Juncheng Wei, PhD is an Assistant Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University, and also holds an Assistant Professor position at the Center for Metabolic Disease Research. His academic career focuses on the intersection of metabolism, endoplasmic reticulum stress, and disease pathogenesis, with particular emphasis on lipid and glucose metabolism in metabolic disorders. Dr. Wei received his PhD from Peking Union Medical College, Tsinghua University, China. His educational background provided a strong foundation in biomedical research that has informed his current work on metabolic pathways and their dysregulation in disease states. Dr. Wei's research primarily focuses on lipid and glucose metabolism and their roles in metabolic disease . His work extensively investigates the Endoplasmic Reticulum-Associated Degradation (ERAD) pathway, particularly the SEL1L-HRD1 complex, and its critical functions in hepatic metabolism, immune regulation, and cancer progression. His laboratory explores how ER stress signaling contributes to conditions including liver disease , breast cancer metastasis , and metabolic disorders . A significant portion of his research examines the role of deubiquitinating enzymes , particularly USP22, in cancer stemness, metastasis, and tumor immune evasion. Analysis of Dr. Wei's publication record over the past five years reveals a consistent focus on the molecular mechanisms connecting protein quality control systems with metabolic regulation and disease pathogenesis. His work demonstrates an increasing emphasis on the intersection of metabolism and immunology, particularly how ER stress pathways influence immune cell function in the tumor microenvironment. Recent publications show expanding research into computational approaches for therapeutic development, as evidenced by his work on antibody language models for antiviral therapy. Alpha-1 Foundation Research Award PSC find a cure Research Award Dr. Wei leads a productive research program with numerous collaborative projects across multiple disciplines. His work involves substantial grant funding supporting investigations into metabolic disease mechanisms, liver pathophysiology, and cancer metabolism. His laboratory maintains active collaborations with immunology and cancer research groups, reflecting the interdisciplinary nature of his work. Dr. Wei's research team focuses on elucidating the molecular connections between protein homeostasis, metabolic regulation, and disease pathogenesis, with particular emphasis on translating basic discoveries into potential therapeutic approaches for metabolic disorders and cancer.

• Cell Biology
• Biochemistry
• Molecular Biology
• +۳ مورد دیگر

Rafaella Konstantinou is a Research Fellow specializing in molecular mechanisms related to cell matrix biology and regenerative medicine. Her work focuses on extracellular matrix dynamics, particularly the interaction between tensin3 and talin in fibronectin-associated fibrillar adhesions. Education: Bachelor of Science from The University of Manchester (2017) Master in Science from King's College London (2015) Research Interests: Rafaella's research explores the structural and functional roles of proteins like fibronectin, vinculin, and integrins in cell adhesion and matrix assembly, with implications for regenerative medicine and mechanobiology. Scientific Awards: 2017/18 Clinical Neuroscience Silver Medal IJEP Short-Talk Prize (2021) Collaborative Networks: Recent collaborations span international institutions, with active research outputs in cell biology and biochemistry. Her work aligns with UN Sustainable Development Goals related to education and scientific innovation.

Matteo Amitaba Mole'مشاهده پروفایل

استادیار

• Human Embryo Implantation
• Reproductive Biology
• Stem Cell Biology
• +۴ مورد دیگر

Matteo Amitaba Mole' is an Assistant Professor in the Department of Obstetrics and Gynecology at Stanford University, specializing in Reproductive, Perinatal & Stem Cell Biology Research. He is faculty member of the Division of Reproductive, Stem Cell and Perinatal Biology, the Dunlevie Maternal-Fetal Medicine Center for Discovery, Innovation and Clinical Impact, and the Stanford Institute for Stem Cell Biology and Regenerative Medicine. He also holds memberships in Bio-X, the Cardiovascular Institute, and the Maternal & Child Health Research Institute (MCHRI). Dr. Mole' received his PhD from University College London (UCL) and completed postdoctoral research fellowships at the University of Cambridge and the Babraham Institute. During his postdoctoral work, he established a license under the UK Human Fertilisation and Embryology Authority (HFEA) to conduct research on human embryos donated by patients undergoing IVF. Dr. Mole's research focuses on investigating the complex process of human embryo implantation, which has been traditionally referred to as the enigmatic stage of human embryonic development due to limited availability of suitable model systems. His laboratory has developed three-dimensional cell-engineered systems that closely recapitulate the cytoarchitecture of the human endometrium, providing a unique opportunity to investigate human implantation in vitro . His work aims to study the mechanobiology and key features of tissue receptivity that support successful implantation. Analysis of Dr. Mole's publications reveals a strong focus on embryonic development, particularly human embryo implantation and early developmental processes. His research spans comparative studies between human and mouse development, cellular mechanisms of implantation, and the molecular crosstalk at the embryo-maternal interface. His work combines advanced techniques including single-cell analyses, tissue engineering, and live-imaging to unravel the complexities of early human development. Dr. Mole' actively mentors students and postdoctoral scholars across multiple programs including Stem Cell Biology and Regenerative Medicine, Biophysics, and Maternal-Fetal Medicine. His laboratory provides research opportunities for undergraduate students, graduate students, and postdoctoral fellows interested in reproductive biology and early embryonic development. The Mole' Laboratory is located at the Lorry I. Lokey Stem Cell Research Building at Stanford University. The lab focuses on modeling the human endometrium, studying implantation of the human embryo in vitro , and developing therapeutics for implantation enhancement. The research team includes a lab manager, postdoctoral scholars, PhD students, and undergraduate researchers working collaboratively to advance understanding of human embryo implantation.

Ceren Mutgan Redolfiمشاهده پروفایل

پژوهشگر

• Vascular Biology
• Pulmonary Arterial Hypertension
• Extracellular Matrix
• +۲ مورد دیگر

Ceren Mutgan Redolfi works as a Postdoctoral Fellow at Lund University's medical faculty. Her research focuses on vascular biology and pulmonary arterial hypertension, with particular emphasis on proteoglycan expression, versican isoforms, and endothelial dysfunction. Key research areas include: Vascular pathology in pulmonary hypertension Extracellular matrix remodeling Proteolytic processing mechanisms Collagen-derived mediators in endothelial dysfunction Recent publications highlight her work on versican localization (2025, The Journal of Histochemistry and Cytochemistry ), comparative imaging studies of pediatric pulmonary diseases (2024, Pulmonary Circulation ), and proteoglycan mapping in hypertensive pulmonary arteries (2024, American Journal of Physiology - Lung Cellular and Molecular Physiology ). She actively collaborates with multidisciplinary teams across Europe and contributes to open-access biomedical research.

Christine Supina Pavićمشاهده پروفایل

مدرس ارشد

• Molecular Biology
• Genetics
• Biochemistry
• +۳ مورد دیگر

Christine Supina Pavić is a Senior Lecturer at the Ruđer Bošković Institute, specifically within the Division of Molecular Medicine and the Laboratory for Protein Dynamics. Her research focuses on DNA-protein crosslink repair mechanisms and their implications in cancer biology and developmental genetics. Research Interests: Molecular Biology, Genetics, DNA Repair, Zebrafish Models, Cancer Therapy Education: Completed her diploma thesis at the Faculty of Science, University of Zagreb (2018). Collaborations: Active in international workshops (EMBO) and collaborative studies with teams in Croatia, Germany, and Singapore. Her recent publications highlight work on proteases like GCNA/ACRC and segregase enzymes in DNA repair, with applications in oncology and developmental biology. She has advised students such as Marin Kutnjak on DNA-protein crosslink repair projects. The DNA repair studies in her laboratory utilize zebrafish as a model organism to explore cellular responses to DNA damage and protease roles in maintaining genomic stability. Her work intersects pharmacology and cancer biology, particularly in combination therapies targeting integrin pathways. Current efforts in the Laboratory for Protein Dynamics focus on elucidating protease functions in DNA-protein crosslink repair, with potential implications for therapeutic strategies in triple-negative breast cancer and melanoma.

Ohad Medaliaمشاهده پروفایل

استاد

• Cryo-electron tomography
• Structural biology
• Macromolecular complexes
• +۴ مورد دیگر

Ohad Medalia is a Full Professor of Biochemistry at the University of Zurich, specializing in cryo-electron tomography (cryo-ET) . His research investigates macromolecular structures and mechanisms in eukaryotic cells , with a focus on integrin-mediated adhesion, intermediate filaments, and nuclear envelope organization. Education: B.Sc. in Chemistry (Tel-Aviv University), Ph.D. in Chemistry (Weizmann Institute), Postdoc (Max-Planck Institute) Research: Combines cryo-ET, FIB-milling, AFM, and biochemical tools to study lamin assemblies, actin polarity, and cell adhesion dynamics Scientific Awards: ERC Synergy Grant (2018), Honorary Doctorate (2023), FEI European Microscopy Award (2008), Alon Fellowship (2004), Rothschild Fellowship (2001) Students: Supervises multiple PhD students including Clarens Lionel, Montinaro Carlotta, and Master student Peyer Tristan His recent publications highlight structural insights into laminopathies , intermediate filament mechanics , and actin-cytoskeleton interactions . Collaborations span institutions like Max Planck Institute, Ben Gurion University, and European research networks.

Tim Lämmermannمشاهده پروفایل

استاد

• Immunology
• Cell Migration
• Inflammation
• +۷ مورد دیگر

Tim Lämmermann is a Full Professor and Director of the Institute of Medical Biochemistry at the University of Münster since October 2023. He leads a research group focused on immune cell dynamics, particularly neutrophil swarming, macrophage networks, and mast cell functions in inflammation. Previously, he served as a group leader at the Max Planck Institute of Immunobiology and Epigenetics (2015–2024) and trained as a postdoc at the NIH/NIAID (2009–2014) and PhD student at the Max Planck Institute of Biochemistry (2004–2009). His work integrates cell biology, immunology, and metabolomics. Education: Undergraduate in Molecular Medicine, University of Erlangen-Nürnberg PhD, Max Planck Institute of Biochemistry Research Interests center on innate immune cell migration and inflammatory signaling , with key contributions to understanding neutrophil swarming, mast cell survival mechanisms, and macrophage network dynamics. His team employs intravital imaging, metabolomics, and genetic models to dissect immune responses in vivo. Publications (2022–2024) highlight interdisciplinary themes bridging immunology, cell biology, and metabolic regulation. Recent studies explore integrin-mediated migration, Arp2/3 complex functions, and microbiota-driven inflammation. His lab has pioneered methods for rare cell analysis and live imaging of immune processes.

Volker Gerkeمشاهده پروفایل

استاد

• membrane lipid dynamics
• membrane trafficking
• membrane-cytoskeleton interactions
• +۵ مورد دیگر

Volker Gerke is a Professor at the University of Münster, serving as Director of the Center for Molecular Biology of Inflammation (ZMBE) and Co-Spokesperson of the Cluster of Excellence "Cells in Motion." He leads the Gerke Lab within the Institute of Medical Biochemistry and holds key positions including Executive Board member of the Cells in Motion Interfaculty Centre, Member of the Research and Careers Committee, Supervisor in the CiM-IMPRS Graduate Programme, and Member of the Imaging Network – Microscopy. Gerke's research focuses on cellular membrane dynamics, with particular emphasis on membrane lipid dynamics, membrane trafficking, membrane-cytoskeleton interactions, and calcium signaling pathways. His work investigates how cellular membranes are structured and how they regulate diverse cellular processes including cell shape changes, cell movement, and membrane transport. A significant portion of his research examines exocytosis mechanisms in endothelial cells, particularly the function of Weibel-Palade bodies (WPBs) which play crucial roles in wound healing and inflammatory responses. His laboratory studies how WPBs are structured, how they form, and how they function to regulate vascular homeostasis. Analysis of Gerke's recent publications reveals a consistent focus on membrane biology with particular attention to annexin proteins, calcium signaling, and endothelial cell function. His work spans fundamental membrane biophysics to physiological applications in vascular biology and inflammation. Recent publications demonstrate increasing interdisciplinary collaboration, integrating advanced imaging techniques, nanotechnology for intracellular delivery, and sophisticated cell biological approaches to address complex questions in membrane dynamics. As a supervisor in the CiM-IMPRS Graduate Programme, Gerke mentors the next generation of scientists in cell dynamics and imaging. His laboratory maintains strong connections with multiple research networks including the Imaging Network and Cells in Motion consortium, facilitating interdisciplinary research approaches. The Gerke Lab collaborates extensively with researchers studying cell adhesion, membrane trafficking, and inflammation. The Gerke Lab is part of the Center for Molecular Biology of Inflammation at the University of Münster, which provides state-of-the-art facilities for advanced microscopy and cell biological research. The lab maintains strong connections with the broader Cells in Motion research cluster, enabling access to cutting-edge imaging technologies and collaborative opportunities across multiple disciplines focused on cellular dynamics.

• Angiogenesis
• Vascular biology
• Endothelial cell specialization
• +۷ مورد دیگر

Professor Ralf H. Adams is a leading vascular biologist jointly appointed as Professor at the University of Münster Medical Faculty and as Director of the Department of Tissue Morphogenesis at the Max Planck Institute for Molecular Biomedicine in Münster, Germany. He is a core member of the Cells in Motion Cluster of Excellence and actively participates in the CiM-IMPRS graduate programme. Research Interests Molecular regulation of angiogenesis Organ-specific specialization of endothelial cells and pericytes Coupling of vascular growth to bone formation and remodeling Characterisation of vascular niches for stem and progenitor cells Single-cell transcriptomic and imaging approaches to study vascular morphogenesis His recent work has uncovered specialized bone capillary subtypes that orchestrate osteogenesis and demonstrated how age-related loss of these vessels contributes to osteoporosis. The laboratory combines advanced mouse genetics, high-resolution intravital microscopy, single-cell multi-omics, and 3-D biomimetic culture systems to dissect how endothelial-derived signals instruct tissue morphogenesis and regeneration. Scientific Output & Trends Over the past decade Adams has published >150 peer-reviewed articles in leading journals ( Nature , Cell Stem Cell , Nature Communications , eLife , Circulation ). The 2023–2025 corpus centres on four major themes: (i) identification of distinct endothelial subtypes regulating bone and haematopoietic niches; (ii) Apelin and Eph-ephrin signaling in neuro-inflammation and vascular integrity; (iii) single-cell dissection of developmental and age-related vascular heterogeneity; and (iv) translational exploitation of these insights to combat osteoporosis, retinopathy and fibrotic disease. Advising & Service Member, Research & Careers Commission, Max Planck Institute Münster Management Board member, CiM-IMPRS Graduate Programme Supervises a multi-disciplinary team of post-docs, PhD students and technicians (~25 members) Frequent keynote speaker at international vascular biology and bone meetings Laboratory & Core Facilities The Adams Lab – Tissue Morphogenesis is embedded within the Multiscale Imaging Centre , providing access to state-of-the-art confocal, two-photon, light-sheet and electron microscopy, FACS, single-cell genomics, transgenic mouse and advanced histology cores. The group co-directs the Imaging Network that services the wider Münster biomedical campus.

Oliver Söhnleinمشاهده پروفایل

استاد

• Inflammation
• Atherosclerosis
• Neutrophils
• +۳ مورد دیگر

Oliver Söhnlein is a Professor of Regulatory Mechanisms of Inflammation and Director of the Institute of Experimental Pathology at the University of Münster, Germany. He is a leading researcher in neutrophil biology and its role in vascular inflammation, particularly in atherosclerosis. Education: MD (2004) from Friedrich-Alexander University Erlangen, PhD (2008) from Karolinska Institutet Current Leadership: Institute Director, Speaker of DFG-funded TRR332 Collaborative Research Center Research Focus: His work explores how neutrophils contribute to vascular inflammation, atherosclerosis progression, and tissue damage during conditions like acute lung injury and myocardial infarction. His team investigates mechanisms such as NET release, ROS production, and histone-mediated lytic cell death. Publication Trends: Recent articles highlight neutrophil functions in metabolic stress, atherosclerosis acceleration via endotoxinemia, and chrono-pharmacological interventions for inflammation. Key subfields include monocyte adhesion , inflammasome activation , and phagocyte mobilization .