جست‌وجوی استاد و پژوهشگر

Michael Wallaceمشاهده پروفایل

استادیار

• Electrophysiology
• Motivated Behavior
• Basal Ganglia
• +۷ مورد دیگر

Michael Wallace serves as an Assistant Professor at Boston University, leading research at the intersection of basal ganglia circuitry, motivated behavior, and synaptic transmission mechanisms. His work addresses fundamental questions about neural control of goal-directed actions and their disruption in neurological disorders. Education: Ph.D. in Neurobiology from the University of North Carolina at Chapel Hill Dr. Wallace's research program centers on genetically defined circuits within the basal ganglia, investigating how these structures guide motivated behaviors and motor control. His laboratory employs a sophisticated multidisciplinary toolkit including in vivo electrophysiology, optogenetics, molecular genetics, computational modeling, and behavioral assays. Key research themes encompass neurotransmitter cotransmission (particularly GABA/glutamate interactions), synaptic vesicle dynamics, and circuit-level pathophysiology in conditions ranging from Parkinson's disease to addiction. The lab's long-term mission targets therapeutic interventions through mechanistic understanding of neural circuit dysfunction. Analysis of his publication record reveals consistent focus on multitransmitter neurons and basal ganglia microcircuitry since 2011, with increasing emphasis on entopeduncular nucleus function and neurotransmitter co-packaging mechanisms. His work demonstrates methodological evolution from anatomical and transcriptional profiling toward real-time circuit interrogation using optogenetic and electrophysiological approaches. The Wallace Lab operates as a dynamic neuroscience research hub, integrating expertise across molecular, cellular, and systems levels. Current investigations leverage cutting-edge techniques to dissect how specific basal ganglia pathways process motivational signals and motor commands, with particular attention to disease-relevant perturbations. This systems neuroscience approach bridges fundamental circuit mechanisms with translational applications for neurological and psychiatric disorders.

Paola Arlottaمشاهده پروفایل

استاد

• Neuroscience
• Developmental Biology
• Stem Cell Biology
• +۳ مورد دیگر

Paola Arlotta is the Golub Family Professor and Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is a principal faculty member at the Harvard Stem Cell Institute, an Institute Member at the Broad Institute, and an Associate Member of the Stanley Center for Psychiatric Research. Her career spans groundbreaking work in cortical development and regenerative neuroscience. Education: M.S. in Biochemistry from the University of Trieste, Italy Ph.D. in Molecular Biology from the University of Portsmouth, UK Postdoctoral training in Neuroscience at Harvard Medical School Dr. Arlotta’s research focuses on defining molecular pathways that govern the differentiation of neural progenitors into cortical projection neurons, with a special interest in corticospinal neurons linked to ALS and spinal cord injury. Her lab bridges developmental neuroscience with stem cell engineering to study human-specific cortical development using 3D organoid models, aiming to uncover mechanisms of neurodevelopmental diseases. Scientific Contributions: 2024: Discovery of individual susceptibility to neurotoxicity in brain chimeroids 2024: Microglia’s role in fetal brain inflammation response 2022: Autism risk genes affect asynchronous neuron class development 2019: Reproducible generation of human cortical diversity in organoids Scientific Awards: Elected to the National Academy of Medicine for pioneering brain organoid research Her lab employs advanced techniques like single-cell RNA sequencing, FIN-seq for frozen tissue analysis, and in utero electroporation. She also explores neuronal reprogramming and myelin dynamics across axons, contributing to understanding cortical circuit assembly and repair.

Hysell Oviedoمشاهده پروفایل

استادیار

• Neural Circuits
• Vocal Communication
• Auditory Neuroscience
• +۳ مورد دیگر

Hysell Oviedo serves as the Roger M. Perlmutter Career Development Assistant Professor of Biomedical Research in the Department of Neuroscience at Washington University School of Medicine. His research program investigates neural circuit mechanisms underlying vocal communication, with emphasis on hemispheric lateralization in auditory processing across species. Education: 1998: BS/BA in Biology and French Literature, Stockton University 2004: PhD in Neuroscience, New York University Dr. Oviedo's work leverages rodent models to decode evolutionarily conserved mechanisms of vocal communication, revealing lateralized processing of acoustic features in the auditory cortex. His laboratory employs an integrated approach combining spatial transcriptomics, quantitative synaptic circuit mapping, high-density in vivo electrophysiology, ethological behavior analysis, and activity mapping. This multidisciplinary strategy addresses how neural circuits develop specialized computational roles for decoding social vocalizations in noisy environments, with direct relevance to communication disorders. Analysis of his publication record demonstrates consistent focus on auditory cortex lateralization, circuit asymmetries, and temporal processing mechanisms. His research bridges molecular, cellular, and systems neuroscience, revealing how recurrent connectivity strength (2022), inhibitory motifs (2017), and molecular regulators like PTEN (2012) shape hemispheric specialization for vocal communication. Scientific recognition: Roger Perlmutter Career Development Professorship, Washington University Dr. Oviedo leads an active research program funded through the Perlmutter Career Development Professorship, directing the Oviedo Lab's investigations into neural circuit development and dysfunction. While specific grant details aren't enumerated, his career development award provides substantial support for training researchers in advanced neuroscience methodologies. The lab maintains collaborative ties within WashU Neuroscience and beyond. The Oviedo Lab operates as a dynamic neuroscience research unit within Washington University's neuroscience community, utilizing cutting-edge tools to investigate auditory cortical specialization. Current projects focus on molecular pathways of auditory cortex maturation (via spatial transcriptomics), circuit asymmetry mechanisms (using quantitative synaptic mapping), and behavioral correlates of vocal communication processing through ethological paradigms like pup retrieval.

Shang Muمشاهده پروفایل

استادیار

• Connectomics
• Neuroscience
• Mouse Visual Cortex
• +۵ مورد دیگر

Shang Mu serves as Assistant Professor of Research in Neuroscience at the Brain and Mind Research Institute, Weill Cornell Medical College since 2022. His work focuses on high-resolution neural circuit mapping using advanced connectomics techniques, particularly in mouse visual cortex and human brain disorders. His educational background includes: Ph.D. in Biomedical Engineering from University of Florida (2010) B.Eng. in Biomedical Engineering from Beijing University, China (2005) Dr. Mu's research spans connectomics, neural circuit architecture, and computational neuroscience. He investigates synaptic organization, inhibitory specificity, and wiring rules in cortical circuits using electron microscopy and machine learning. His work has significant implications for understanding neurological diseases including stroke and glioblastoma. Key methodologies involve large-scale image analysis, transcriptomic integration, and development of open-source tools for connectome annotation. Analysis of his 15 most recent publications (2024-2025) reveals a dominant focus on mouse visual cortex connectomics, with emerging work on human brain disorders. Major themes include inhibitory circuit specificity, dendritic morphology mapping, and computational tool development (CAVE, NEURD). His research demonstrates consistent high-impact output in top journals like Nature and Cell , often featuring collaborative, interdisciplinary approaches combining neuroscience, genomics, and computer science. No scientific awards are documented in the provided materials. Information regarding student advising, grant funding, or specific laboratory teams is not available in the current dataset. His research is conducted within the Brain and Mind Research Institute infrastructure at Weill Cornell Medical College.

Andrea Hasenstaubمشاهده پروفایل

استاد

• Auditory physiology
• Cortical microcircuitry
• Neurodevelopmental disorders
• +۳ مورد دیگر

Andrea Hasenstaub is a Professor in the Department of Otolaryngology-Head and Neck Surgery at the University of California, San Francisco (UCSF), affiliated with the Coleman Memorial Laboratories. She holds roles as Principal Investigator and Co-Principal Investigator on multiple NIH-funded projects focusing on auditory cortex function and cortical circuitry. Education: BS: California Institute of Technology, Mathematics and Engineering M.Phil.: Cambridge University, Biological Anthropology PhD: Yale University, Neurobiology Research Interests: Dr. Hasenstaub’s work centers on understanding auditory processing, inhibitory microcircuitry in the cortex, and human-specific neural specializations. Her lab uses advanced optical and genetic tools to study how cortical interneurons regulate neural activity in health and disease. Key areas include: Genetic and cellular mechanisms of auditory cortex dysfunction in conditions like tinnitus Comparative studies of cortical organization across species (mouse, human) Cross-modal interactions between auditory and visual systems Grants & Funding: NIH R01NS116598: Cortical circuitry supporting audiovisual interactions NIH R01MH122478: Protocadherin regulation of interneuron survival NIH R01DC014101: Cortical inhibition and auditory context processing Labs & Collaborations: Her lab collaborates with researchers like Arturo Alvarez-Buylla and Christoph Schreiner, focusing on interneuron transplantation, human brain development, and circuit dysfunction in neurodevelopmental disorders.

• Neuroscience
• Alzheimer's Disease
• Parkinson's Disease
• +۳ مورد دیگر

Ajit Ray serves as a Special Faculty-Senior Researcher at Carnegie Mellon University's Neuroscience Institute, an interdisciplinary research hub focused on advancing neural computation and systems neuroscience. His primary affiliation centers on investigating molecular mechanisms underlying neurodegenerative disorders through the institute's collaborative framework. Ray's research concentrates on Alzheimer's and Parkinson's disease pathogenesis with emphasis on redox signaling disruptions and cytoskeletal dynamics. Key investigations include amyloid-β-induced F-actin disassembly in dendritic spines, glutaredoxin-mediated neuroprotection against oxidative damage, and early hippocampal hyperexcitability in amyloidosis models. His work bridges molecular neuroscience with behavioral outcomes using transgenic mouse models, quantitative fluorescence imaging, and electrophysiological approaches to elucidate synaptic dysfunction mechanisms. Analysis of his publication record reveals a cohesive trajectory since 2016 where F-actin pathology serves as a unifying theme across neurodegenerative conditions. His most significant contributions demonstrate glutaredoxin-1's therapeutic potential in restoring cytoskeletal integrity and cognitive function, with recent work expanding into thalamocortical plasticity during sensory learning. This research program consistently connects molecular redox events to circuit-level alterations and behavioral deficits. No verifiable information exists regarding student mentorship, grant funding, or laboratory teams in the source materials. Similarly, details about educational background, scientific awards, or future research directions remain undocumented in the provided texts.

Solange Brownمشاهده پروفایل

دانشیار

• Systems Neuroscience
• Cognitive Neuroscience
• Computational Neuroscience
• +۸ مورد دیگر

Solange Brown is an Associate Professor in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University School of Medicine. Her research focuses on the functional organization of neocortical circuits and their role in perception, cognition, and disease. She is affiliated with multiple graduate programs including the Neuroscience Training Program, Cellular and Molecular Medicine, Biochemistry, Cellular and Molecular Biology, and the XDBio Cross-Disciplinary Graduate Program in Biomedical Sciences. Research Interests: Dr. Brown's work integrates physiological, anatomical, and genetic techniques to study how neocortical circuits process information. Her lab investigates synaptic integration in local circuits, the role of long-range inputs in perception, and how cortical outputs drive behavior. Research spans systems, cognitive, and computational neuroscience, with emphasis on neural circuits, connectomics, and the neurobiology of disease. Techniques include patch-clamp recordings, optogenetics, fluorescent labeling, and optical monitoring of neuronal activity. Publication Trends: Her recent publications (2000–2018) reflect a consistent focus on cortical microcircuitry, synaptic dynamics, and the role of specific neuron types in circuit function. Themes include the claustrum, ALS models, sleep regulation, and transcriptional identity of projection neurons, demonstrating a multidisciplinary approach combining molecular, cellular, and systems neuroscience. Scientific Awards: No awards explicitly mentioned in the text. Advising and Grants: Dr. Brown actively mentors graduate students, postdoctoral fellows, and undergraduates, as evidenced by her recruitment efforts and co-authorship with junior researchers. Her lab receives funding to support research on neocortical circuit function and dysfunction, though specific grants are not listed. She contributes to major collaborative studies, particularly in ALS and neural connectivity. Labs and Teams: The Brown Lab investigates how neocortical circuits generate perception and action, using a bottom-up approach. The team employs advanced techniques to map and manipulate neural circuits, with a focus on both healthy function and disease mechanisms. Lab members include postdocs, graduate students, and undergraduates engaged in interdisciplinary neuroscience research.

Jochen Staigerمشاهده پروفایل

استاد

• Neuroanatomy
• Cortical Microcircuits
• Thalamo-Cortical Interactions
• +۱۲ مورد دیگر

Jochen Staiger is a Full Professor and Director of the Department of Neuroanatomy at the University Medical Center Göttingen, University of Göttingen, where he leads research on cortical microcircuits and thalamo-cortical interactions. He is affiliated with multiple graduate programs under the Göttingen Graduate Center for Neurosciences (GGNB), including Neurosciences (IMPRS), Sensory and Motor Neuroscience, Cellular and Molecular Physiology of the Brain (CMPB), and Molecular Biology of Cells (GZMB). Dr. med., Justus Liebig University Giessen (1993), summa cum laude Habilitation in Anatomy, Heinrich Heine University Düsseldorf (2000) W3 Professor of Cell Biology, Albert-Ludwigs-University Freiburg (2006) His research focuses on the synaptic architecture of neocortical microcircuits, particularly in the barrel cortex, examining how thalamo-cortical inputs shape cortical processing, how inhibitory interneurons organize layer-specific circuits, and how sensory experience drives genomic and structural plasticity. He uses transgenic mouse models, including the reeler mutant, to study cortical function in both normally laminated and dysplastic cortices. The recent publications (2015–2020) reflect a strong focus on VIP and parvalbumin-expressing interneurons, neuromodulation, layer-specific connectivity, and functional organization of cortical columns. Key themes include synaptic targeting, burst-tonic transitions, brain-wide connectivity mapping, and compensation in malformed cortices. No scientific awards were mentioned in the provided text. Prof. Staiger leads an active research group with a focus on fundamental neuroscience questions. His lab investigates how cortical circuits develop, function, and adapt, with implications for understanding neurodevelopmental disorders. The team employs advanced neuroanatomical, genetic, and imaging techniques to dissect circuit motifs. While no formal students are listed, his collaborative publications suggest mentorship of junior researchers. His research group maintains a dedicated homepage: http://www.neuroanatomie.uni-goettingen.de/ and a specialized site on barrel cortex research: http://neuro.ukat.gwdg.de/barrels/ .

Torkel Haftingمشاهده پروفایل

استاد

• Systems Neuroscience
• Neural Circuits
• Spatial Memory
• +۵ مورد دیگر

Torkel Hafting is a Professor of Neuroscience at the University of Oslo's Institute of Basic Medical Sciences, part of the Faculty of Medicine. He leads the Cortical Circuits Group and serves as Chair of the Physiology Section (since 2019). His research focuses on systems neuroscience, neural circuits, spatial/social memory, and perception, with a particular emphasis on perineuronal nets and their role in stabilizing neural networks. His work integrates electrophysiology, genetic engineering, and advanced microscopy to study how sensory information is processed and stored in neural networks. He holds a Dr.Scient. in Physiology (2005) from the University of Oslo, following earlier degrees from the University of Oslo and the University Center in Svalbard. Key awards include the Fridtjof Nansen Award (2007) and the I.K. Lykkes Award (2006). He collaborates widely, including with CINPLA (Center for Integrative Neuroplasticity), the Leutgeb Lab (UC San Diego), and Simula Research Laboratory. Hafting's teaching includes neurophysiology modules in medical education (MED1100, MED2200) and advanced courses like PSY4304 and MF9150. His research projects include the BrainChip initiative, a multidisciplinary effort to develop wireless brain probes for rodent studies, funded by the Norwegian Research Council. Recent publications highlight breakthroughs in understanding perineuronal nets' role in grid cell stability, optogenetic manipulation of neural circuits, and topological analysis of visual cortex activity. His lab's tools (e.g., Exdir, Expipe) are widely used in neuroscientific data management.

Ikuko Smithمشاهده پروفایل

استادیار

• Neuroscience
• Neural Circuitry
• Dendritic Computation
• +۳ مورد دیگر

Ikuko Smith is an Assistant Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of California, Santa Barbara. Her research focuses on elucidating the cellular and network mechanisms of neural circuitry, particularly the role of dendritic spikes in information processing. She employs advanced techniques such as electrophysiology, two-photon imaging, and behavioral analyses to study sensory perception and neural circuit dynamics. Research Interests: Dr. Smith investigates how dendrites contribute to synaptic computations and their functional roles in behaving animals. Her work highlights the computational power of dendritic spikes and examines their integration into microcircuitry. Techniques include patch clamp recordings from distal dendrites and novel imaging technologies like the Cousa objective for multiphoton imaging. Recent Articles Trends: Her recent work explores unconventional NMDA receptors, mesoscale cortical architecture, and neuroimaging software advancements. She also examines interneurons’ impact on synaptic integration and the ripple effects of single neurons in network dynamics. Labs/Teams: Her lab develops cutting-edge imaging tools and studies dendritic computation in vivo. Collaborations span neurotechnology and systems neuroscience.

Brett R Schofieldمشاهده پروفایل

استاد

• Auditory Neuroanatomy
• Neural Circuitry of Hearing
• Neurotransmitter Systems
• +۴ مورد دیگر

Brett R Schofield serves as a Distinguished University Professor at Northeast Ohio Medical University (NEOMED) within the College of Graduate Studies and Department of Anatomy and Neurobiology. He joined NEOMED in 2005 as a founding member of the Hearing Research Group and has maintained continuous NIH funding since 1998 for his work on auditory neuroanatomy. Dr. Schofield received his Honors B.A. in Biology from the University of Delaware (1981) and Ph.D. in Anatomy from Duke University (1986), followed by postdoctoral training in neuroscience at Duke. His academic journey includes teaching medical neuroscience at Duke University, the University of South Dakota, and the University of Louisville before arriving at NEOMED. His research focuses on the functional anatomy of brain circuits that enable hearing, particularly examining how acetylcholine and GABA neurotransmitter systems contribute to selective attention, speech understanding, and neural adaptation during development, aging, and after injury. His laboratory employs traditional and viral tract-tracing techniques to investigate descending auditory pathways, cholinergic circuitry, inhibitory cell types, and the organization of inferior colliculus subclasses. Dr. Schofield's recent publications (2018-2023) reveal a consistent focus on characterizing specific neural populations in the auditory pathway, particularly examining cholinergic inputs, GABAergic cell subtypes, and neuropeptide-expressing neurons in the inferior colliculus and related structures. His work demonstrates increasing sophistication in neural classification and connectivity mapping within the auditory system. CP White Research Fellowship (University of Delaware) James A. Shannon Director's Award (NIH) American Medical Women's Association Gender Equity Award (University of Louisville) Outstanding Faculty Research Award (NEOMED) NIH/NIDCD R01 DC004391 (2021-2026) NIH/NIDCD R01 DC018284 subaward (2020-2025) NIH/NIDCD R01 DC016918 (2019-2023) As a Graduate Faculty member, Dr. Schofield teaches Medical Neuroscience to medical and graduate students, Brain Mind and Behavior to graduate students, and Current Research in Auditory Neurobiology. His laboratory, part of NEOMED's Hearing Research Focus Area, continues to investigate fundamental questions about how neural circuits process sound information, with implications for understanding hearing disorders, tinnitus, and neural plasticity.

Satoru Kondoمشاهده پروفایل

دانشیار

• Neural Circuits
• Synaptic Organization
• Visual Information Processing
• +۳ مورد دیگر

Satoru Kondo is a Project Associate Professor in the Department of Integrative Physiology at The University of Tokyo's Graduate School of Medicine and a Specially Appointed Associate Professor at the International Research Center for Neurointelligence (IRCN). He also serves as Core Manager of the Imaging Core facility. His academic journey includes a PhD in Medicine from The University of Tokyo (1995), preceded by graduate studies at Tokyo Institute of Technology and undergraduate training at Kanazawa University. His research focuses on understanding neural circuits for visual information processing using advanced imaging techniques. Key interests include: Synaptic organization in visual cortical pathways Neuronal integration mechanisms via two-photon microscopy Functional microarchitecture of orientation selectivity In vivo analysis of synapse dynamics and glial interactions Kondo's publications demonstrate consistent focus on visual neurophysiology, with recent work emphasizing synaptic input architecture and large-scale neural imaging. His 25+ articles show progression from molecular neuroscience to systems-level circuit analysis. Awards & Recognition: Human Frontier Science Program Long-Term Fellowship (1995) Research Leadership: He leads multiple funded projects including AMED-supported development of novel bio-optical imaging techniques (2021-2024) and JSPS-funded work on synaptic input mechanisms (2020-2023). As Imaging Core Manager, he oversees advanced microscopy resources for neuroscience research.

• Neuroscience
• Sensory Systems
• Neural Dynamics
• +۳ مورد دیگر

Jagruti Pattadkal is a Research Fellow at the Center for Perceptual Systems within the College of Liberal Arts at the University of Texas at Austin. Her research focuses on understanding neural mechanisms underlying sensory processing, particularly in visual systems and oculomotor behaviors. She employs advanced neurophysiological techniques and comparative approaches in rodents and primates to investigate neural circuit dynamics. Her work bridges basic neuroscience with applied neurotechnology, emphasizing long-term neural recording methods and functional characterization of neuronal subtypes. Current projects include studying interactions between eye movement control systems in marmosets and exploring how sensory amplification mechanisms operate in primate neocortex. Past work has examined visual system development in mice and functional organization of motion-sensitive neurons using 2-photon imaging. Key research themes include: neural synchrony dynamics, primate oculomotor behavior, sensory plasticity, and cross-species comparisons of visual processing. This multidisciplinary approach integrates experimental neuroscience with computational modeling to uncover fundamental principles of brain function. Pattadkal's publications since 2015 reflect her sustained focus on sensory systems, with recent emphasis on neural recording technology advancements and understanding how cortical circuits process complex visual information. She collaborates across disciplines to advance our understanding of perceptual systems in both health and disease contexts.

David McCormickمشاهده پروفایل

استاد

• Neural Networks
• Cortical Function
• Behavioral Neuroscience
• +۱ مورد دیگر

Professor David McCormick is a Professor of Biology and Neuroscience at the University of Oregon's College of Arts and Sciences. His research investigates neural networks underlying brain function, focusing on mechanisms of optimal behavioral performance and cortical processing. Research examines how brain states (arousal levels) influence sensory processing, decision-making, and learning. Current projects investigate vagus nerve stimulation effects, cortical ensemble dynamics, and neuromodulatory control of brain states using advanced imaging and electrophysiological techniques. Recent publications explore how arousal modulates neural coding efficiency, how neuromodulatory systems coordinate behavioral states, and how cortical circuits generate complex behaviors. This work combines electrophysiology, imaging, and behavioral analysis in awake, behaving animals. Professor McCormick leads an active research laboratory developing new methods for large-scale neural recording and analysis. The lab maintains collaborations investigating neural basis of well-being and positive psychology interventions.

Melissa Hermanمشاهده پروفایل

دانشیار

• Inhibitory microcircuitry
• Alcohol Use Disorder
• Neuronal Network Dysfunction
• +۵ مورد دیگر

Melissa Herman, PhD, is an Associate Professor in the Department of Pharmacology at the University of North Carolina School of Medicine and a member of the Bowles Center for Alcohol Studies. Her research focuses on inhibitory neuronal networks, particularly how GABAergic signaling regulates brain function and dysregulation associated with alcohol and drug addiction. She investigates the role of tonic and synaptic inhibition in regions like the amygdala, nucleus tractus solitarius, and ventral tegmental area. Key research areas include: Inhibitory microcircuitry governing motivated behaviors and dependence Alcohol-induced changes in tonic inhibition and neuronal excitability Nicotine and vaping effects on reward circuits and neuronal activity Psilocybin’s impact on serotonin systems and addiction-related behaviors Her work combines electrophysiological techniques with behavioral paradigms to dissect mechanisms underlying substance use disorders. Recent publications emphasize sex differences, stress interactions, and translational models of addiction. Labs/Teams: The Herman Lab explores neuroplasticity in alcohol/drug effects, focusing on GABAergic networks. Current projects include investigating nicotine vaping’s impact on dopamine signaling and psilocybin’s potential in treating addiction.