Solange Brown

Solange Brown is an Associate Professor in the Solomon H. Snyder Department of Neuroscience at Johns Hopkins University School of Medicine. Her research focuses on the functional organization of neocortical circuits and their role in perception, cognition, and disease. She is affiliated with multiple graduate programs including the Neuroscience Training Program, Cellular and Molecular Medicine, Biochemistry, Cellular and Molecular Biology, and the XDBio Cross-Disciplinary Graduate Program in Biomedical Sciences.

Research Interests: Dr. Brown's work integrates physiological, anatomical, and genetic techniques to study how neocortical circuits process information. Her lab investigates synaptic integration in local circuits, the role of long-range inputs in perception, and how cortical outputs drive behavior. Research spans systems, cognitive, and computational neuroscience, with emphasis on neural circuits, connectomics, and the neurobiology of disease. Techniques include patch-clamp recordings, optogenetics, fluorescent labeling, and optical monitoring of neuronal activity.

Publication Trends: Her recent publications (2000–2018) reflect a consistent focus on cortical microcircuitry, synaptic dynamics, and the role of specific neuron types in circuit function. Themes include the claustrum, ALS models, sleep regulation, and transcriptional identity of projection neurons, demonstrating a multidisciplinary approach combining molecular, cellular, and systems neuroscience.

Scientific Awards:

• No awards explicitly mentioned in the text.

Advising and Grants: Dr. Brown actively mentors graduate students, postdoctoral fellows, and undergraduates, as evidenced by her recruitment efforts and co-authorship with junior researchers. Her lab receives funding to support research on neocortical circuit function and dysfunction, though specific grants are not listed. She contributes to major collaborative studies, particularly in ALS and neural connectivity.

Labs and Teams: The Brown Lab investigates how neocortical circuits generate perception and action, using a bottom-up approach. The team employs advanced techniques to map and manipulate neural circuits, with a focus on both healthy function and disease mechanisms. Lab members include postdocs, graduate students, and undergraduates engaged in interdisciplinary neuroscience research.