Ikuko Smith

Ikuko Smith is an Assistant Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of California, Santa Barbara. Her research focuses on elucidating the cellular and network mechanisms of neural circuitry, particularly the role of dendritic spikes in information processing. She employs advanced techniques such as electrophysiology, two-photon imaging, and behavioral analyses to study sensory perception and neural circuit dynamics.

Research Interests: Dr. Smith investigates how dendrites contribute to synaptic computations and their functional roles in behaving animals. Her work highlights the computational power of dendritic spikes and examines their integration into microcircuitry. Techniques include patch clamp recordings from distal dendrites and novel imaging technologies like the Cousa objective for multiphoton imaging.

Recent Articles Trends: Her recent work explores unconventional NMDA receptors, mesoscale cortical architecture, and neuroimaging software advancements. She also examines interneurons’ impact on synaptic integration and the ripple effects of single neurons in network dynamics.

Labs/Teams: Her lab develops cutting-edge imaging tools and studies dendritic computation in vivo. Collaborations span neurotechnology and systems neuroscience.