جست‌وجوی استاد و پژوهشگر

Adviye Ergulمشاهده پروفایل

استاد

• Vascular complications of diabetes and hypertension
• Acute ischemic stroke
• Alzheimer's Disease Related Deteriorias
• +۵ مورد دیگر

Adviye Ergul is a Professor at the Medical University of South Carolina in the Department of Pathology and Laboratory Medicine. She holds secondary appointments at Augusta University and the Charlie Norwood VA Medical Center. Her research focuses on vascular complications of diabetes and hypertension, acute ischemic stroke, and Alzheimer's disease-related dementias, with specific emphasis on endothelial cell biology and vascular pathology. Education : MD from Cerrahpasa Medical School (Istanbul, Turkey, 1987), PhD in Biochemistry & Molecular Biology from University of Miami School of Medicine (1995), postdoctoral training in Vascular Biology at University of Georgia. Her work explores mechanisms of endothelin system dysfunction , microvascular senescence , and inflammatory pathways in diabetic and hypertensive conditions. Recent studies investigate novel therapies like angiotensin receptor agonists and iron chelation for post-stroke cognitive impairment. She has published extensively on diabetes-stroke interactions , endothelin signaling , and sex differences in vascular disease. Key research trends include neurovascular unit remodeling , microemboli-mediated dementia , and mitochondrial quality control in brain injury. Her laboratory developed diabetic stroke models to test interventions like linagliptin and bosentan . Awards : NIH Individual Research Service Award, American Heart Association Scientist Development Award, Veterans Administration Research Career Scientist, Regents’ Professorship, Phi Kappa Phi Honor Society.

Donald Fraserمشاهده پروفایل

استاد

• Nephrology
• Chronic Kidney Disease
• Peritoneal Dialysis
• +۴ مورد دیگر

Professor Donald Fraser serves as Director of the Division of Infection and Immunity and Director of the Wales Kidney Research Unit within Cardiff University's School of Medicine. Clinically active as a consultant nephrologist at Cardiff and Vale University Health Board, he leads internationally recognized research on kidney injury mechanisms and fibrosis in chronic kidney disease and peritoneal dialysis contexts. His educational background includes an MB ChB from the University of Bristol (1993), membership in the Royal College of Physicians (1996), PhD from University of Wales College of Medicine (2003), and Certificate of Completion of Training in General Medicine and Nephrology (2006). Fraser's research program investigates fibro-proliferative disorders through multiple approaches: MicroRNA biomarker discovery for kidney disease progression Mechanisms of peritoneal membrane injury during dialysis Inflammatory pathways in renal scarring Translational models of kidney fibrosis His work bridges basic science with clinical applications, focusing on diagnostic tools and therapeutic targets for conditions with limited treatment options. Analysis of his 15 most recent publications reveals strong emphasis on molecular mechanisms of kidney injury (73%), biomarker development (60%), and translational models (47%), with increasing integration of single-cell technologies and machine learning approaches since 2021. Key recognitions include: Health and Care Research Wales Lead Researcher (2013) American Society of Nephrology Travel Scholarship (2011) Sir Jules Thorne Scholarship (2010) Clinician Scientist Fellowship (2005) Kidney Research UK Clinical Training Fellowship (2000) As an academic supervisor, Fraser currently leads one PhD student as principal supervisor and four as cosupervisor, having previously guided 12 doctoral candidates to completion. His research program receives consistent funding from Health and Care Research Wales and Kidney Research UK, with recent projects focusing on peritoneal dialysis outcomes and microRNA-based diagnostics. He directs the Wales Kidney Research Unit's All-Wales strategy for kidney disease research and co-leads the Division of Infection and Immunity's internationally cited research program spanning basic immunology to clinical applications in human health.

Martin Kaczochaمشاهده پروفایل

دانشیار

• Lipid Signaling
• Endocannabinoid System
• Inflammatory Pain Mechanisms
• +۴ مورد دیگر

Martin Kaczocha, PhD, is an Associate Professor at Stony Brook University in the Department of Anesthesiology , with affiliations in Biochemistry and Cell Biology . His research focuses on fatty acid binding proteins (FABPs) and their role in endocannabinoid signaling , inflammatory pain , and cancer progression . Research Interests : FABP modulation of endocannabinoid pathways Mechanisms of inflammatory and postsurgical pain Lipid signaling in prostate and hepatocellular cancers Phytocannabinoid interactions with intracellular proteins Scientific Contributions : Developed FABP5 inhibitors for pain and cancer Elucidated FABPs' role in retrograde synaptic signaling Linked FABP5 to taxane-resistant prostate cancer Identified FABP1's impact on THC biotransformation Awards : Young Academic Inventor's Award, Stony Brook NAI Chapter Associate Editor, BMC Anesthesiology Recent Publications : 2024: FABP5's role in tumor immune rewiring (Nature Metabolism) 2024: FABP5 inhibition in osteoarthritis pain (Osteoarthritis Cartilage) 2024: Novel FABP5 inhibitors for neuropathic pain (Journal of Pharmacology) 2023: FABP5 in docetaxel-resistant cancer (Cancers) Students : Livia Schutz (Graduate) Faniya Doswell (Graduate) Mohammad Fauzan (Graduate) Kai Bou (Masters) The Kaczocha lab collaborates with departments including Chemistry , Biochemistry , and Applied Mathematics , with funding from NIDA , NIMH , and NCI . Current projects explore FABP5's role in neuropathic pain , prostate cancer metastasis , and phytocannabinoid mechanisms .

• Genetics
• Genomics
• Whole-exome sequencing
• +۶ مورد دیگر

Thomas Kitzler is a Scientist at the Montreal University Health Centre (IR-MUHC) and an Assistant Professor in the Department of Human Genetics at McGill University . His research focuses on genetic and genomic mechanisms of kidney diseases , particularly congenital anomalies of the kidney and urinary tract (CAKUT) , focal segmental glomerulosclerosis , and renal ciliopathies . Affiliations : Center for Translational Biology Child Health and Human Development Program Division of Genetics, MUHC His laboratory utilizes whole-exome sequencing , zebrafish models , and patient-derived cell systems to uncover novel disease genes and pathways. Recent publications highlight discoveries in COL4A1 , ZMYM2 , and C2CD3 mutations linked to renal and neurodevelopmental disorders. Dr. Kitzler actively contributes to genetic characterization of nephrotic syndromes and polycystic kidney diseases , with a focus on precision medicine approaches for kidney transplant recipients and circulating podocyte-toxic factors in recurrent glomerular diseases. His work demonstrates interdisciplinary integration of clinical, genomic, and functional validation methods.

Andrew Sandstromمشاهده پروفایل

استادیار

• Immunology
• Innate Immunity
• Inflammasome Biology
• +۳ مورد دیگر

Andrew Sandstrom is an Assistant Professor in the Department of Immunology at The University of Texas Southwestern Medical Center, where he leads research on molecular immune recognition mechanisms since 2021. His work bridges structural biology and immunology to decipher pathogen detection pathways. His academic trajectory includes postdoctoral training in the Division of Immunology and Pathogenesis at the University of California Berkeley (2014-2020) and doctoral studies in Biochemistry and Molecular Biology at the University of Chicago (2008-2014). Dr. Sandstrom's research centers on innate immunity with dual emphases: (1) inflammasome activation mechanisms, particularly NLRP1's response to pathogen enzymes through functional degradation, and (2) γδ T-cell recognition via butyrophilin molecules and phosphoantigens. His lab employs structural, biochemical, and cellular approaches to uncover fundamental principles of immune surveillance, with implications for inflammatory diseases and cancer immunotherapy. Current projects investigate fungal gasdermin-like proteins and conformational control of T-cell receptors. Publication analysis reveals evolving focus from structural biology (aquaporin, 2009) to specialized immune mechanisms. Recent work (2018-2020) demonstrates leadership in inflammasome biology, highlighting NLRP1's activation logic and gasdermin functions. Earlier studies (2011-2014) established foundational insights into γδ T-cell antigen recognition through butyrophilin-3A1 and TCR conformational changes. The Sandstrom Lab maintains active collaborations and welcomes new partnerships, as evidenced by the lab's public outreach for research involvement and collaboration opportunities. The team investigates molecular pathways through which the immune system detects infection and cellular stress, with ongoing projects featured on their dedicated lab website.

• Creativity
• Cognitive Neuroscience
• Psychophysiology
• +۳ مورد دیگر

Christian Rominger is a Senior Lecturer at the Institute of Psychology , Faculty of Natural Sciences, University of Graz. His research focuses on the intersection of creativity, psychophysiology, and interoception, particularly examining relationships between physical activity, heart rate variability (HRV), and cognitive performance. Current project: Investigating dose-response relationship between physical activity and creativity Methodological expertise: Ambulatory monitoring, EEG alpha power analysis Research trends in his publications include: Psychophysiological mechanisms underlying creativity HRV as biomarker for stress and interoceptive awareness Development of just-in-time adaptive interventions (JITAI) for mental health

• Pharmacogenomics
• Clinical Pharmacology
• Drug Safety
• +۵ مورد دیگر

Mia Wadelius is a Professor at the Department of Medical Sciences specializing in Clinical Pharmacogenomics and Osteoporosis at Uppsala University. With an MD qualification, she has established herself as a leading researcher in pharmacogenomics and clinical pharmacology, focusing on how genetic variations affect drug responses and adverse reactions. Her research interests span multiple critical areas in personalized medicine, including: Pharmacogenomics of anticoagulant therapy, particularly warfarin dosing Genetic associations with drug-induced adverse reactions Pharmacovigilance and risk prediction for adverse drug events Genetic factors influencing drug metabolism and response Precision medicine applications in clinical practice Professor Wadelius's extensive publication record demonstrates her leadership in pharmacogenomics research. Her recent work has focused on vaccine-related adverse events, anticoagulant therapy, chemotherapy toxicity in pediatric oncology, and genetic factors in drug-induced liver injury. Her research employs advanced genomic techniques including genome-wide association studies (GWAS), whole genome sequencing, and meta-analyses to identify genetic variants associated with drug responses. Her scientific contributions include numerous high-impact publications in journals such as npj Vaccines, European Journal of Clinical Pharmacology, and Scandinavian Journal of Immunology. Her work has significantly advanced our understanding of how genetic factors influence individual responses to medications, paving the way for more personalized and safer drug therapies. Professor Wadelius has been instrumental in developing pharmacogenetic guidelines and has contributed to major collaborative research efforts in pharmacogenomics. Her work bridges basic genetic research with clinical applications, aiming to translate genomic discoveries into improved patient care and medication safety.

Stefan Dudliمشاهده پروفایل

استاد

• Rheumatology
• Modic changes research
• Complex Regional Pain Syndrome
• +۶ مورد دیگر

Professor Stefan Dudli is a leading researcher at the Center of Experimental Rheumatology, University Hospital Zurich, Department of Rheumatology. He heads the Dudli Lab, a growing satellite research group located at the Balgrist Campus, where his team focuses on the pathophysiology of rheumatic disorders and novel therapeutic development. His work bridges rheumatology and orthopedics with a particular emphasis on spinal conditions and pain mechanisms. Professor Dudli's research spans multiple interconnected domains centered on spinal pathology. His primary focus is on Modic changes - vertebral bone marrow lesions associated with idiopathic low back pain. His lab has demonstrated that these changes represent inflammatory and fibrotic alterations in bone marrow where the adjacent degenerated intervertebral disc plays a critical role. His research has established animal and in vitro models showing dual etiologies: disc infection and autoimmune responses against disc material can both trigger Modic changes. A secondary major research focus is Complex Regional Pain Syndrome (CRPS), particularly investigating the epidermal communication between neuronal and non-neuronal cells in CRPS skin to understand precise pathogenesis. Analysis of Professor Dudli's recent publications reveals a strong translational research trajectory moving from basic pathophysiological understanding toward therapeutic development. His work shows increasing sophistication in methodology, incorporating advanced techniques like transcriptomic profiling, flow cytometry screening, and biomechanical modeling. The research demonstrates particular strength in bridging basic science with clinical applications, especially in developing targeted treatments for Modic changes and understanding biological subgroups in CRPS. Professor Dudli leads a multidisciplinary research team focused on spinal pathology and pain mechanisms. The Dudli Lab employs diverse technical expertise including primary cell isolation from multiple tissues (bone marrow, intervertebral discs, synovium, skin), advanced cell culture models, and comprehensive cellular characterization techniques. His research benefits from close clinical partnerships that enable translation of basic discoveries into potential therapies for painful spinal conditions.

• Sports Sciences
• Exercise Physiology
• Renal Hemodynamics
• +۵ مورد دیگر

Professor Seiji Maeda is affiliated with Waseda University's Faculty of Sport Sciences since 2021. Previously, he held professorial positions at the University of Tsukuba (2003-2021) within the Faculty of Health and Sport Sciences. He earned both his M.S. and Ph.D. from the University of Tsukuba in sports medicine. Education: M.S. (1993), Ph.D. (1996), University of Tsukuba Research Interests focus on Sports Sciences , particularly: Exercise-induced cardiovascular adaptations Renal hemodynamics in aging populations Physical activity's role in chronic kidney disease Mechanisms of arterial stiffness and baroreflex sensitivity Neurophysiological impacts of endurance training Article Trends (2022-2024) reveal expertise in: Renal biomarker analysis in CKD patients Physical activity interventions for arterial stiffness Neurovascular adaptations in athletes Hormonal responses to exercise in obesity Cultural exercise programs for aging populations Scientific Awards include: Otsuka Sports Medicine and Science Award (multiple years) Japan Society of Physical Fitness and Sports Medicine awards Asian Federation of Sports Medicine accolades Special commendations for education research His Professional Memberships span: Japanese Society of Clinical Sports Medicine Japan Society of Physical Education, Health and Sport Sciences Japan Society of Exercise and Sports Physiology Japanese Society of Physical Fitness and Sports Medicine

Dörte Hamannمشاهده پروفایل

استاد

• Immunology
• Clinical Immunology
• Medical Immunology
• +۹ مورد دیگر

Dörte Hamann is a Full Professor affiliated with the University Medical Center Utrecht, focusing on the Strategic Program Infection & Immunity . She specializes in Medical Immunology and Laboratory Medicine, integrating immunological diagnostics with broader clinical specialties. Her research spans immunological diagnostics, autoimmune diseases, HIV immunology, and clinical applications of immunology in oncology, neurology, and rheumatology. She has contributed to studies on SARS-CoV-2's impact on autoantibodies, immune checkpoint inhibitor side effects, and anti-MOG-associated demyelinating syndromes. Key article trends include immunodiagnostics, autoimmune disease mechanisms, and translational research linking basic immunology to clinical practice.

Alberto De Lucaمشاهده پروفایل

استادیار

• Diffusion MRI
• Neurological Diseases
• Brain Connectivity
• +۳ مورد دیگر

Alberto De Luca is an Assistant Professor at the Image Sciences Institute, Division Imaging & Oncology, University Medical Center Utrecht. He holds a BSc in Biomedical Engineering (2011), MSc in Bioengineering (2013), and PhD (2017) from the University of Padova, Italy, where his thesis focused on non-Gaussian diffusion in the brain and skeletal muscle. His research specializes in diffusion MRI methodologies for neurological diseases and cancer, with key interests including: Fiber-specific quantification in grey/white matter Multi-center MRI data harmonization Physiological parameter estimation via inverse methods Response prediction modeling He leads projects in cerebral small vessel disease and pediatric oncology, utilizing advanced 7T MRI and AI techniques. Recent publications (2025) demonstrate strong focus on: AI-driven lesion-symptom mapping in vascular cognitive disorders Diffusion MRI harmonization across research sites Advanced tractography validation frameworks Pediatric cancer imaging biomarkers He contributes to the Translational Neuroimaging Group and International Society for Tractography, with external collaborations including Erasmus MC (Frontotemporal dementia research) and Hogeschool Utrecht (guest lecturing on brain networks).

Roberto Bomprezziمشاهده پروفایل

دانشیار

• Neuroimmunology
• Multiple Sclerosis
• Demyelinating Diseases
• +۵ مورد دیگر

Roberto Bomprezzi, MD, PhD, is an Associate Professor of Neurology at the University of Massachusetts Chan Medical School, Associate Clinical Director of the Neuroimmunology & Multiple-Sclerosis Center, and a fellowship-trained neuro-immunologist who has been on the UMass faculty since 2014. He previously served as faculty at Barrow Neurological Institute (2008-2012) and as an attending neurologist at Maine General Neurology (2012-2014). Education: MD, Sapienza University of Rome, Rome, Italy PhD, Experimental Neurobiology, Sapienza University of Rome Neurology residency, St Joseph’s Hospital, Phoenix, Arizona Neuro-immunology fellowship, Barrow Neurological Institute, Phoenix, Arizona Research & Clinical Focus: Dr. Bomprezzi leads clinical and translational projects that optimize immune-modulating therapy for neuro-inflammatory disorders, develop imaging biomarkers of chronic inflammation, and conduct phase-II/III trials of new MS agents. His work integrates advanced MRI-PET imaging, precision dosing strategies for natalizumab, and collaborative consensus efforts for rare conditions such as neurosarcoidosis. Publication Trends: Across 50+ peer-reviewed papers since 1999 his scholarly output maps the evolution of MS therapeutics—from early genome-wide expression and twin studies, through the introduction of natalizumab and dimethyl fumarate, to present-day Bruton-tyrosine-kinase inhibition and PET-based microglial imaging. Recurrent themes are individualized therapy, extended-interval dosing, safety surveillance, and biomarker-guided treatment. Teaching & Mentoring: He maintains >15 years of continuous education activity, instructing medical students, residents, fellows, and post-docs, and serves as an international invited speaker on neuro-immunological topics. Clinical Trials Leadership: He is principal or co-investigator on multiple active trials at UMass Memorial, contributes to consensus guideline panels, and directs the Neuroimmunology Fellowship program that trains the next generation of subspecialists.

Mark Heiseمشاهده پروفایل

استاد

• Virology
• Immunology
• Vaccine Development
• +۵ مورد دیگر

Mark Heise, PhD, is a Professor at the UNC School of Medicine, with dual appointments in the Department of Genetics and Microbiology and Immunology . He is a member of the UNC Lineberger Comprehensive Cancer Center , where his research focuses on virus-host interactions and vaccine development. His laboratory investigates mechanisms of viral immunomodulation and genetic factors influencing disease susceptibility. Specialties: Virology, Immunology, Vaccine Development Email: mark_heisem@med.unc.edu Location: 9039 Burnett Womack Building, UNC-Chapel Hill His research has significant implications for: Understanding how viruses manipulate innate immune systems Developing safer vaccine vectors through codon optimization Identifying genetic markers for differential vaccine responses Exploring mitochondrial gene downregulation during SARS-CoV-2 infection Advancing RNA-based therapies for infectious diseases Improving immunotherapies for vulnerable populations

Terrence Fureyمشاهده پروفایل

استاد

• Epigenetics
• Gene Regulation
• Inflammatory Bowel Diseases (IBD)
• +۴ مورد دیگر

Dr. Terrence (Terry) Furey is a Professor in the Department of Genetics and Biology at the UNC School of Medicine. His research focuses on gene regulatory processes, particularly epigenetically controlled mechanisms, and their role in complex diseases like inflammatory bowel diseases (IBD). The Furey Lab specializes in computational analysis of genome-wide open chromatin, histone modifications, miRNA, and gene transcription data from high-throughput sequencing experiments. Key research areas: Epigenetics, Chromatin Biology, IBD Pathogenesis, Computational Genomics, Microbiome Interactions Specialized methodologies: Development of statistical and computational tools for genomic data analysis Research highlights include investigating genetic and epigenetic contributors to IBD through collaborations with Dr. Shehzad Sheikh, particularly analyzing chromatin reprogramming, miRNA expression, and microbial composition in both IL-10 knockout models and human intestinal tissues. The lab has identified distinct molecular signatures of Crohn's disease associated with clinical phenotypes. Article trends demonstrate expertise spanning Chromatin accessibility analysis in disease states MicroRNA biomarker discovery in IBD Computational tool development (ROCCO, DeFCoM, GSAASeqSP) Multi-omics integration in complex phenotypes Environmental-genetic interaction studies Translational IBD research Dr. Furey actively collaborates with researchers across the Center for Gastrointestinal Biology and Disease (CGIBD), including Drs. Sartor, Sheikh, and Rusyn. His work bridges clinical/translational research with microbiome studies , focusing on how epigenetic landscape alterations contribute to disease progression.

• Obsessive-compulsive disorder (OCD)
• Tourette syndrome
• Genetic epidemiology
• +۵ مورد دیگر

Dr. Marco A. Grados is an Assistant Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine and Co-Director of the Tourette Syndrome Center of Excellence at Kennedy Krieger Institute and Johns Hopkins Medicine. With a career spanning over two decades at Johns Hopkins, he has established himself as a leading researcher in the genetic epidemiology of obsessive-compulsive disorder (OCD) and Tourette syndrome. Dr. Grados completed his undergraduate and medical training in Lima, Peru, followed by internship and residency at Henry Ford Health Systems in Detroit. He joined Johns Hopkins in 1994 as a child psychiatry fellow and chief resident, and later earned a Master's of Public Health in genetic epidemiology from Johns Hopkins School of Public Health. After six years as medical director of outpatient programs at Kennedy Krieger Institute, he now focuses primarily on research in genetic epidemiology of OCD and related disorders. His research interests center on the genetic basis of OCD and Tourette syndrome, with significant contributions to large-scale genetic studies including the OCD Genetics Consortium and Tourette Syndrome Association International Genetics Consortium. He also investigates autoimmune aspects of OCD and uses Cornelia de Lange syndrome as a model to understand autism and obsessive-compulsive traits. His work has been published in high-impact journals including Nature Genetics, Biological Psychiatry, and American Journal of Medical Genetics. Dr. Grados has received substantial research funding, including a five-year Research Career Development Award from the National Institute of Mental Health (2002-2007), support from the Obsessive-Compulsive Foundation, and funding from the CdLS-USA Foundation. His recent work in 2025 includes genome-wide association studies identifying genetic loci associated with OCD and tic disorders, as well as important research on Cornelia de Lange syndrome. Research Career Development Award from the National Institute of Mental Health (2002-2007) Active funding from Obsessive-Compulsive Foundation for autoimmune OCD research Support from CdLS-USA Foundation for Cornelia de Lange syndrome research As Co-Director of the Tourette Syndrome Center of Excellence, Dr. Grados bridges clinical care and research, providing expertise in the diagnosis and treatment of Tourette syndrome while advancing our understanding of its genetic underpinnings. His work on the intersection of genetics, neuroimmunology, and behavior continues to shape our understanding of neuropsychiatric disorders.