معرفی
Martin Kaczocha, PhD, is an Associate Professor at Stony Brook University in the Department of Anesthesiology, with affiliations in Biochemistry and Cell Biology. His research focuses on fatty acid binding proteins (FABPs) and their role in endocannabinoid signaling, inflammatory pain, and cancer progression.
- Research Interests:
- FABP modulation of endocannabinoid pathways
- Mechanisms of inflammatory and postsurgical pain
- Lipid signaling in prostate and hepatocellular cancers
- Phytocannabinoid interactions with intracellular proteins
- Scientific Contributions:
- Developed FABP5 inhibitors for pain and cancer
- Elucidated FABPs' role in retrograde synaptic signaling
- Linked FABP5 to taxane-resistant prostate cancer
- Identified FABP1's impact on THC biotransformation
- Awards:
- Young Academic Inventor's Award, Stony Brook NAI Chapter
- Associate Editor, BMC Anesthesiology
- Recent Publications:
- 2024: FABP5's role in tumor immune rewiring (Nature Metabolism)
- 2024: FABP5 inhibition in osteoarthritis pain (Osteoarthritis Cartilage)
- 2024: Novel FABP5 inhibitors for neuropathic pain (Journal of Pharmacology)
- 2023: FABP5 in docetaxel-resistant cancer (Cancers)
- Students:
- Livia Schutz (Graduate)
- Faniya Doswell (Graduate)
- Mohammad Fauzan (Graduate)
- Kai Bou (Masters)
The Kaczocha lab collaborates with departments including Chemistry, Biochemistry, and Applied Mathematics, with funding from NIDA, NIMH, and NCI. Current projects explore FABP5's role in neuropathic pain, prostate cancer metastasis, and phytocannabinoid mechanisms.
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