جستجوی استاد راهنمای دانشگاهی

Fabeha Fazalمشاهده پروفایل

دانشیار

• Pulmonary Medicine
• Cell Biology
• Molecular Pathology
• +۴ مورد دیگر

Fabeha Fazal, Ph.D. is an Associate Professor in the Department of Pediatrics at the University of Rochester Medical Center. Her research focuses on understanding the molecular mechanisms of Acute Lung Injury (ALI)/ARDS pathogenesis, particularly how endothelial cell dysfunction and inflammation contribute to disease progression. Current lab projects explore the role of endoplasmic reticulum BiP and mitochondrial GRP75 in ALI, as well as the link between endothelial cytoskeletal dynamics and inflammatory gene expression. She employs in vitro and in vivo models, including LPS-induced sepsis and thrombin-induced inflammation , to identify novel therapeutic targets for ALI. Her publications reveal expertise in NF-κB signaling , actin cytoskeleton regulation , and organelle crosstalk in inflammatory lung disorders. She has received NIH R01 grants for studying "Regulation of Endothelial-Neutrophil Interaction and Lung Vascular Permeability in Sepsis." Education: PhD in Biochemistry, A.M. University (1992) MSc in Biochemistry, A.M. University (1987) BSc in Chemistry, A.M. University (1985) Scientific Recognition: University Gold Medal for top M.S. Examination (1987) University Gold Medal for top B.S. Examination (1985) Lab Personnel: Collaborates with Principal Investigator Dr. Arshad Rahman and post-doctoral researchers like Dr. Pei Yi Su. Lab technicians and trainees include Antony Leonard (Technical Associate) and previous graduate researcher Moyinoluwa D Adenuga.

• Drug Delivery
• Nanotechnology
• Targeted Therapeutics
• +۵ مورد دیگر

Silvia Muro is a Group Leader and ICREA Research Professor at the Institute for Bioengineering of Catalonia (IBEC), affiliated with the University of Barcelona. Her research focuses on developing advanced drug delivery systems using nanotechnology to overcome biological barriers and improve therapeutic outcomes. She leads the Targeted Therapeutics and Nanodevices research group, which investigates how to precisely deliver therapeutic agents to specific disease sites within the body. Dr. Muro's laboratory specializes in understanding the biological mechanisms that regulate cellular transport of therapeutic agents. Her team has pioneered approaches to control biological events beyond receptor binding, enabling precise drug delivery through modulation of nanocarrier properties. The research focuses on three main areas: Biologically-Controlled Transport of Drug Carriers - studying how size, shape, targeting valency, receptor epitopes, and signaling molecules affect transport Transport Across Physiological Barriers - particularly the blood-brain barrier and epithelial barriers for neurological and gastrointestinal drug delivery Treatment of Lysosomal Disorders - applying nanotechnology to enzyme replacement therapy for diseases like Niemann-Pick, Fabry, and Gaucher Analysis of Dr. Muro's recent publications reveals a strong emphasis on ICAM-1 targeted nanocarriers for overcoming biological barriers. Her work demonstrates how nanocarrier properties can be engineered to control transport kinetics and destinations. A significant portion of her research addresses neurological disease treatment and lysosomal storage disorders through innovative DNA-built nanocarriers that enable cellular uptake and endosomal escape. While specific awards aren't detailed in available information, Dr. Muro's position as an ICREA Research Professor represents a prestigious recognition of research excellence in Catalonia. Her publications in high-impact journals demonstrate significant research funding and international collaborations. Dr. Muro leads an active research laboratory investigating drug delivery challenges for neurological diseases and genetic disorders. Current projects include developing nanocarriers that cross the blood-brain barrier and designing systems for enzyme replacement therapy in lysosomal storage disorders, with considerable translational potential for treating conditions that currently lack effective therapies.

• Liver Immunology
• Immune Tolerance
• Transplant Immunology
• +۵ مورد دیگر

Associate Professor Patrick Bertolino at the University of Sydney's Central Clinical School leads the Liver Immunology Program at the Centenary Institute. With 20+ years of international recognition in liver immunology , he pioneered discoveries about CD8+ T cell activation and hepatocyte-mediated immune tolerance , including the paradigm-shifting finding that liver-activated T cells are deleted via hepatocyte lysosomes. His work bridges transplantation immunology , chronic hepatitis , and malaria vaccine development using transgenic mouse models . Trained by immunology luminaries: Chantal Rabourdin-Combe (ENS-Lyon), Jacques Miller (WEHI), Barbara Fazekas de St Groth (Centenary Institute) Continuous NHMRC funding since 2000: 2 Program Grants, 6 Project Grants 2010 NHMRC Senior Research Fellowship Research Themes explore how the liver uniquely regulates immunity: Induces transplant tolerance via T cell deletion Exploits immune subversion in hepatitis B/C and malaria Develops gene therapy and mRNA vaccines for liver-targeted immunity Investigates hepatitis C reinfection post-transplant Article Trends show sustained focus on T cell-liver interactions , with recent work on mRNA vaccines (2023), neuroinflammation in GVHD (2024), and long-lived TRM cells in malaria (2025). Publications span high-impact immunology , hepatology , and transplantation journals . Awards include: 2010 NHMRC Senior Research Fellowship 2009 Centenary Institute student paper award 1999 Kevin Lafferty Prize for Autoimmunity 1997 University of Sydney U2000 Fellowship Teaching includes 3rd-year Immunology lectures (since 1998). Led liver immunology group since 2011, mentoring students and postdocs. Collaborates with Centenary Institute and National Hepatitis C Elimination Program .

• Pharmacology
• Chemotherapy
• Cytofluorimetry
• +۳ مورد دیگر

Sabrina Pacor is an Associate Professor in Applied Biology (BIO/13) at the University of Trieste , where she teaches Pharmacology in the Pharmacy LM and STB BSc programs. With over 30 years of research experience in experimental oncology and host defense peptides, she has made significant contributions to studying antimicrobial peptides (AMPs) and their interactions with bacterial membranes. Her research focuses on: Direct antimicrobial activity of AMPs against Gram-positive and Gram-negative bacteria Indirect immunomodulatory effects of host defense peptides Development of drug delivery systems using nanomaterials (carbon nanotubes, gold nanoparticles) Mechanistic studies of ruthenium-based antimetastatic drugs She leads extensive cytofluorimetry research using flow cytometry platforms, particularly for evaluating: Cytotoxicity (necrosis/apoptosis, proliferation index) Modulation of host biological responses (chemotaxis, phagocytosis, ROS production) Peptide-bacterial membrane interactions through fluorescent labeling Her recent work demonstrates trends in: Proline-rich antimicrobial peptides against ESKAPE pathogens Hybrid antibiotic design (peptide-aminoglycoside conjugates) Structure-activity relationships in membranolytic peptides Evolutionary insights into defensin and cathelicidin families Prof. Pacor has co-authored over 100 peer-reviewed publications and actively mentors students, having supervised: 70 experimental/thesis reviews for Pharmacy/CTF Master's students 20 Bachelor's degree theses

Jean Krutmannمشاهده پروفایل

استاد

• Molecular Aging Research
• Environmental Medicine
• DNA Repair Deficiency Syndromes
• +۳ مورد دیگر

Prof. Dr. Jean Krutmann leads the Molecular Aging Research group at the Leibniz Research Institute for Environmental Medicine in Düsseldorf. His research focuses on environmentally-induced skin aging , DNA repair deficiency syndromes (Xeroderma pigmentosum, Cockayne syndrome), and air pollution effects on skin . Key projects include DFG FOR5489 exploring AHR-retinoid crosstalk and RTG 2624 developing biostatistical toxicology methods. Research Themes Mitochondrial DNA repair mechanisms Particulate matter dermatotoxicity Cutaneous exposome characterization 3D organoid modeling for UVB responses International environmental health collaborations (India, China) Key Discoveries ICAM-1 regulation in UV-damaged cells Ectoine-based lung disease prevention Near-infrared radiation's role in wrinkle formation Two microbiota cutotypes in Han Chinese AHR as UVB radiation target Collaborations Prof. Klaus Unfried (ectoine research) WG Esser, Schikowski, Schins International dermatology experts (Henry Lim, Akimichi Morita) Core Unit GEMD (iPSC organoids) Training & Leadership : Coordinates DFG research units FOR5489 and RTG 2624 . Supervises PhD student Jennifer Schindler and postdocs. Publications span J. Exp. Med , Nature Cell Biology , and Environmental International .

Mercedes Balcells-Campsمشاهده پروفایل

پژوهشگر

• Tissue Engineering
• Medical Engineering
• Vascular Biology
• +۷ مورد دیگر

Mercedes Balcells-Camps is a Principal Research Scientist at MIT's Institute of Medical Engineering & Science and a Profesora Titular in Bioengineering at Ramon Llull University's Institut Químic de Sarrià. She directs the MIT-Spain Program, fostering academic-industrial collaborations. Education: PhD in Macromolecular Chemistry, RWTH Aachen (1999) MS in Chemistry, Ramon Llull University (1996) MS in Chemical Engineering, Institut Químic de Sarrià (1995) Research Interests focus on tissue engineering , particularly endothelial cell dynamics and microvascular disease . Her work bridges cardiovascular and neuroscience domains, integrating computational modeling , animal models , and cell signaling studies to address vascular injury and neurodegeneration. Key article trends reveal interdisciplinary exploration of Shear stress effects on barrier phenotypes Biomarker expression in atherosclerosis Regenerative strategies using cell implants Uremic thrombosis mechanisms Botanical therapies for vascular disease 3D scaffold optimization for cartilage regeneration Scientific Awards Cross of the Order of the Civil Merit (2011) Borchers-Plakette for Best PhD (1999) La Caixa-DAAD PhD Fellowship (1996-1999) Caixa Manresa Business Plan Competition Winner (2010) Catalan AQU Advanced Research Accreditation (2015) Mentorship & Grants include founding Spain's Regenear startup and chairing MIT's IDEA 2 Global program. She mentors interdisciplinary teams in biomedical innovation and collaborative research , with roles as grant reviewer for Spain's MINECO and Catalonia's AGAUR.

Andrew V. Oleinikovمشاهده پروفایل

استاد

• Malaria pathogenesis
• Placental malaria
• PfEMP1 biology
• +۷ مورد دیگر

Andrew V. Oleinikov, Ph.D. , is a full Professor of Biomedical Science at the Charles E. Schmidt College of Medicine, Florida Atlantic University . Since 2013 he has held a continuous academic appointment, receiving tenure in 2017 and promotion to full professor in 2019. Education M.S. (hons) in Biophysics, St. Petersburg Polytechnical University, Russia, 1983 Ph.D. in Biology, Moscow State University, Russia, 1989 Research Focus Oleinikov’s laboratory integrates molecular parasitology with bioengineering to study Plasmodium falciparum . He investigates how parasite surface proteins—especially the PfEMP1/VAR2CSA family—mediate cytoadherence in placental malaria, aiming to develop vaccines and anti-adhesion drugs. Parallel efforts include building placenta-on-a-chip microfluidic devices and high-throughput screening platforms to accelerate discovery. Earlier work elucidated the role of the endocytic receptor megalin and its adaptor Dab2 in signal transduction, providing foundational insights into receptor-mediated endocytosis. Publication Trends Over the past decade his papers cluster around three themes: (1) functional dissection of PfEMP1 domains and their receptors (ICAM-1, CSA, integrins); (2) translational development of vaccines and small-molecule anti-sequestration agents; and (3) technological innovations—microfluidics, biosensors, and ultra-sensitive molecular diagnostics—for malaria research and placental health. Scientific Awards & Honors FAU Researcher of the Year Award (Associate Professor category), 2018 FAU Degree of Difference Award for graduate teaching, 2015 Faculty Research Mentoring Program Award, 2015 & 2016 Grants & Team Mentorship Oleinikov’s research is continuously funded by NIH (multiple R01, R21, R41) and the Bill & Melinda Gates Foundation. He mentors graduate and undergraduate researchers, many of whom have garnered FAU GRIP grants, 1st-place conference awards, and College of Medicine Student Research Awards. Laboratory & Collaborations He directs an active wet-lab/bioengineering group housed in the Biomedical Science department. Ongoing collaborations include co-investigators in the FAU College of Engineering (Drs. Du and Yi) for microfluidic device fabrication and with international consortia on pregnancy malaria vaccines.

Bilge Güvenç Tunaمشاهده پروفایل

دانشیار

• Biophysics
• Vascular Biology
• Nanotechnology
• +۴ مورد دیگر

Assoc. Prof. Dr. Bilge Güvenç Tuna is an associate professor at Yeditepe University Faculty of Medicine, Department of Biophysics. With a PhD in Biophysics from Universiteit van Amsterdam (2014) and postdoctoral experience at Mayo Clinic, she specializes in vascular aging, nanotechnology applications in cancer diagnostics, and neurophysiology of aging. Her work bridges computational modeling with experimental approaches in cardiovascular disease and bioengineering. PhD: Biophysics, Universiteit van Amsterdam (2014) MSc: Biophysics, Hacettepe University (2008) BSc: Physics (English), Middle East Technical University (2003) Research spans biophysics of vascular remodeling, calorie restriction in cancer models, electrochemical biosensors for colorectal cancer, and neuronal effects of nanomaterials. Her recent publications focus on miRNA profiling in aging, aptamer-based diagnostics, and GPCR signaling in neurological disorders. Key article trends: 2025 studies highlight microbiome biomarkers for colorectal cancer and SUMO-targeted aging mechanisms. Earlier works (2022-2024) emphasize nanoparticle diagnostics, vascular plasticity, and neurodegeneration prevention. Marie Curie Fellow L'Oréal UNESCO Women in Science Award Biophysical Society Travel Grant Multiple poster/prize recognitions Supervised 12+ theses on topics like miRNA in cancer, aptamer diagnostics, and aging vascular mechanics. Led TÜBİTAK and COST projects totaling over 50 million TL in funding. Active in interdisciplinary research linking physics, medicine, and nanotechnology.

• Microbiology
• Infectious diseases
• Immunology
• +۳ مورد دیگر

Dr. Yong Cheng is an Assistant Professor in the Department of Biochemistry and Molecular Biology at Oklahoma State University (OSU). He holds a B.S. (2002) and Ph.D. (2007) in Microbiology from Huazhong Agricultural University, China. His postdoctoral training included work at the University of Basel (2007-2010) and the University of Notre Dame (2011-2019), where he studied host-pathogen interactions in mycobacterial infections. His current research focuses on understanding molecular mechanisms of Mycobacterium tuberculosis and non-tuberculous mycobacteria (NTM) pathogenesis, with an emphasis on host immune responses and drug discovery. Key research areas include the role of extracellular vesicles (exosomes/microvesicles) in modulating host immunity, iron metabolism in aging-related infections, and antimicrobial resistance mechanisms. He has received grants from the Oklahoma Center for Respiratory and Infectious Diseases and investigates novel therapies targeting mycobacterial infections. Dr. Cheng teaches courses on cancer immunology, biotechnology, and undergraduate research supervision. His work contributes to Sustainable Development Goal 3 (Good Health and Well-being), leveraging cutting-edge proteomics and spatial biology technologies.

Elena Lomakinaمشاهده پروفایل

دانشگاهی

• Cell Adhesion
• Immunology
• Biomechanics
• +۳ مورد دیگر

Elena Lomakina, M.D., Ph.D., is a Research Assistant Professor in the Department of Biomedical Engineering at the University of Rochester, School of Medicine and Dentistry. Her research focuses on cellular mechanics, cell adhesion, and the biophysical mechanisms governing leukocyte-endothelial interactions during inflammation. She holds a PhD in Cell Biology from Russian State Medical University (1995) and an MD (1992), followed by postdoctoral training at the University of Rochester (2001–2006). Her work integrates experimental and theoretical approaches to study how mechanical forces and molecular interactions regulate cell behavior. Key areas include the role of cell surface topography in adhesion, glycocalyx-mediated barrier function, and the mechanics of leukocyte migration. Collaborations with the Waugh Lab and others explore red blood cell maturation, microfluidic systems for cell culture, and the dynamics of CAR T cell migration. Lomakina’s research has led to over 25 peer-reviewed articles, including studies on integrin activation, neutrophil phagocytosis, and endothelial glycocalyx properties. Her lab employs advanced techniques like atomic force microscopy and micropipette aspiration to probe cellular mechanics. Ongoing projects investigate the impact of mechanical forces on immune cell function and the development of microfluidic platforms to model vascular inflammation.

Carlos Subausteمشاهده پروفایل

استاد

• Host-Pathogen Interactions
• Cell Signaling in Inflammatory Disorders
• Diabetic Retinopathy
• +۳ مورد دیگر

Carlos Subauste, MD, is a Professor in the Departments of Medicine and Pathology at Case Western Reserve University's School of Medicine. His research focuses on cell signaling pathways in host-pathogen interactions (using Toxoplasma gondii as a model) and inflammatory disorders like diabetic retinopathy and inflammatory bowel disease. He leads the Subauste Laboratory, which develops therapies targeting host-derived signaling pathways to combat infections and inflammatory diseases. Research Interests: Host-pathogen interactions, CD40 signaling in inflammation, autophagy regulation, and translational studies in animal models. Subauste's lab investigates CD40's role in diabetic retinopathy pathogenesis, including its effects on Müller cells, endothelial cells, and inflammatory mediators (e.g., VEGF, nitric oxide). Recent work includes CD40-blocking peptides to inhibit disease progression. Publications highlight mechanistic insights into CD40-driven inflammation and therapeutic strategies. Grants supported by NIH (e.g., P30 EY011373, R01 EY019250) fund his research. His work spans cell signaling, immunology, and translational medicine, with a focus on bridging basic science and clinical applications.

Kaustabh Ghoshمشاهده پروفایل

دانشیار

• Mechanobiology
• Cell-Matrix Interactions
• Vascular Inflammation and Degeneration
• +۴ مورد دیگر

Kaustabh Ghosh is an Associate Professor of Ophthalmology at the University of California, Los Angeles (UCLA) and Principal Investigator at the Doheny Eye Institute. He holds the Mary D. Allen Endowed Chair in Vision Research and is affiliated with the Graduate Programs in Biosciences, MCIP Home Area at UCLA. Academic Background: Bachelor of Technology, National Institute of Technology, Warangal, India Master of Science, Biomedical Engineering, Stony Brook University Doctor of Philosophy, Biomedical Engineering, Stony Brook University Research Focus: Ghosh leads a vascular mechanobiology lab that integrates biology and engineering principles to study vascular degeneration in diabetic retinopathy (DR) and age-related macular degeneration (AMD). His work explores how vascular stiffness contributes to early-stage disease progression, aiming to develop therapies targeting mechanobiological pathways. Publication Trends: His research spans mechanobiology, endothelial dysfunction, and extracellular matrix (ECM) remodeling, with contributions to understanding stiffness-mediated cell signaling (RAGE, Rho), complement-driven injury in AMD, and micromechanical regulation of angiogenesis. Recent work emphasizes translation to clinical interventions for retinal diseases. Scientific Recognition: Catalyst Award for Innovative Research Approaches for AMD (2023) BrightFocus Foundation Featured Scientist (2017) Hellman Fellowship (2014) President’s Award to Distinguished Doctoral Students (2006) Collaborative Impact: Ghosh collaborates with ophthalmologists and engineers, leveraging NIH-funded studies to pioneer novel therapeutic strategies for vision-threatening diseases.

Anja Ramstedt Jensenمشاهده پروفایل

استاد

• Immunology
• Malaria Pathogenesis
• Cerebral Malaria
• +۴ مورد دیگر

Anja Ramstedt Jensen is a Professor in the Department of Immunology and Microbiology at the Faculty of Health and Medical Sciences, University of Copenhagen. She serves as head of the TARGETS research team and holds an Affiliate Professor position with the Department of Immunology and Microbiology, CMP. Her research focuses on Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which plays a critical role in malaria pathogenesis. Dr. Jensen's research interests center on the immunology and pathogenesis of severe Plasmodium falciparum malaria with particular emphasis on cerebral malaria in children. Her work investigates how PfEMP1 proteins enable parasites to adhere to capillaries and contribute to disease development. She is actively involved in enhancing malaria research capacity in Africa and has published extensively on malaria immunology and vaccine development. Her research output shows a strong trend toward understanding the molecular mechanisms of cerebral malaria, with recent publications focusing on PfEMP1 variants, blood-brain barrier disruption, and antibody responses. The work spans structural biology, immunology, and translational research aimed at developing interventions for severe malaria. Her scientific recognition includes: Young Scientist Faculty prize winner, The Faculty of Health Sciences, UCPH (2004) Howard Hughes International Scholar (2005) Lundbeck Ascending Investigator (2019) At the university, Dr. Jensen teaches immunology to undergraduate and graduate students and serves as University Coordinator for the MSc course 'Chronic Inflammation. From Basic Research to Therapy.' Her research group regularly offers bachelor's and master's projects related to malaria research, indicating active mentorship of early-career scientists. The TARGETS team maintains extensive international collaborations, particularly with African research institutions, reflecting her commitment to building malaria research capacity on the continent where the disease burden is highest.

• Cardiovascular Disease
• Hypertension
• Oxidative Stress
• +۴ مورد دیگر

Dr. Augusto Montezano is an Honorary Research Fellow at the University of Glasgow's School of Cardiovascular & Metabolic Health, focusing on hypertension mechanisms, vascular biology, and oxidative stress. His work integrates clinical and experimental research to uncover pathways involving NADPH oxidases (NOX), endothelial dysfunction, and inflammatory processes in cardiovascular diseases. Primary Affiliation: BHF GCRC - ICAMS facility in Glasgow Key Research Areas: Hypertension, vascular inflammation, ACE2/angiotensin system, SARS-CoV-2 vascular effects Recent studies emphasize salt-induced vascular damage via PARP/TRPM2, protective roles of angiotensin peptides, and exosome-mediated cell communication. His translational work bridges basic science and clinical applications, with publications in Hypertension , Journal of Physiology , and Scientific Reports .

• Mechanobiology
• Vascular Biology
• Inflammation
• +۳ مورد دیگر

Kaustabh Ghosh is an Associate Professor in the Department of Ophthalmology at the David Geffen School of Medicine, UCLA, and a member of the Doheny Eye Institute. His research focuses on the mechanobiology of vascular inflammation and degeneration in retinal diseases such as diabetic retinopathy (DR) and age-related macular degeneration (AMD). Education: Ph.D. in Biomedical Engineering (Stony Brook University, 2006), B.Tech in Chemical Engineering (National Institute of Technology, Warangal, 2001). Research Interests: Ghosh’s lab explores how vascular stiffness contributes to early-stage DR and AMD. By integrating vascular biology, mechanobiology, and bioengineering, he investigates factors altering vascular mechanics and their role in degeneration. Key areas include lysyl oxidase (LOX), RAGE signaling, TRPV4 ion channels, and complement system interactions. Publication Trends: Over 15 recent articles highlight mechanosensitive pathways (LOX, TRPV4), retinal vascular stiffness in diabetes and aging, inflammation (ICAM-1, RAGE), and therapeutic approaches (nanotherapeutics, anti-inflammatory peptides). Topics span AMD, DR, tumor vasculature, and biomaterials for wound healing. Scientific Awards: Mary D. Allen Endowed Chair in Vision Research (2025) Catalyst Award for AMD Research (2022) Regents Faculty Development Award (2017) Hellman Fellowship (2014) Lindbergh Lecturer (2011) Grants: Ghosh has received funding from the National Eye Institute/NIH (R01 EY028242, R01EY027440), BrightFocus Foundation (2016–2019), W.M. Keck Foundation (2021–2023), and UCLA Clinical and Translational Science Institute (2022). Labs & Collaborations: Ghosh leads the Ghosh Research Group at the Doheny Eye Institute, collaborating with institutions like Harvard Medical School and the Bio-X Program at Stanford University. His work bridges vascular biology, mechanobiology, and bioengineering to develop therapies targeting vascular stiffness in retinal diseases.