جست‌وجوی استاد و پژوهشگر

• Proteomics
• Mass Spectrometry
• Metatranscriptomics
• +۵ مورد دیگر

LeeAnn Higgins is a Researcher at the Center for Metabolomics and Proteomics at the University of Minnesota. With over 25 years of research activity (since 1995), her work spans proteomics, mass spectrometry, and host-microbe interactions, particularly in clinical contexts like cystic fibrosis and pulmonary hypertension. Key research areas: Ferroptosis, SERPINE1 gene mutations, and aerolysin-based nanobody engineering Recent collaborations focus on metaproteomics workflows and cystic fibrosis disease modeling Contributions to UN Sustainable Development Goals through biomedical research Selected publications demonstrate expertise in: 2025: Ferroptosis inhibition mechanisms in cardiac function 2025: SERPINE1 mutation analysis in canine models 2024: Notch signaling inhibition using pore-forming toxins 2024: Ferroptosis-driven inflammation in pulmonary hypertension 2022: Optimized proteomics workflows for bronchoalveolar lavage fluid Research trends show integration of: Mass spectrometry techniques Metaproteomics for host-microbe dynamics Translational approaches across veterinary and human medicine Contact: higgi022@umn.edu

Daniel Southworthمشاهده پروفایل

استاد

• Molecular Chaperones
• Protein Quality Control
• Neurodegenerative Diseases
• +۳ مورد دیگر

Dr. Daniel Southworth is a Professor in the Department of Biochemistry and Biophysics at the University of California San Francisco (UCSF), affiliated with the Institute for Neurodegenerative Diseases (IND). He earned his BS from UC Santa Cruz and PhD from Johns Hopkins University, followed by postdoctoral training at UCSF. His research focuses on molecular chaperones and protein quality control mechanisms relevant to neurodegenerative diseases like Alzheimer’s and Parkinson’s. Using cryo-electron microscopy (cryo-EM), his lab investigates chaperone machinery structure-function relationships, amyloid aggregation pathways, and therapeutic strategies targeting molecular chaperones. Key research areas include: (1) Structural biology of chaperones like Hsp90, CHIP, and Hsp104; (2) Mechanisms of tau and α-synuclein aggregation; and (3) Development of cryo-EM techniques for studying protein complexes. Recent work has revealed novel filament structures in neurodegenerative diseases and identified polyphosphate’s role in amyloid formation. His lab pioneered studies on VCP/p97 AAA+ ATPases and their adaptors, elucidating their roles in protein quality control. Collaborations include CRISPR-based screening in iPSC-derived neurons and drug design targeting chaperone-driven proteostasis. Notable contributions include cryo-EM structural analysis of SARS-CoV-2 proteins and methodological advancements in cryo-EM imaging using K3 cameras. Current research emphasizes translating structural insights into therapeutic approaches for neurodegenerative disorders.

Qibin Zhangمشاهده پروفایل

استاد

• Analytical Biochemistry
• Biological Mass Spectrometry
• Proteomics
• +۳ مورد دیگر

Qibin Zhang is a Professor of Chemistry and Co-Director of the Center for Translational Biomedical Research at the University of North Carolina at Greensboro (UNCG), where he leads the Zhang Research Group in the Department of Chemistry & Biochemistry within the College of Arts and Sciences. His laboratory develops cutting-edge mass spectrometry technologies for proteomics, lipidomics, and metabolomics with applications in disease biomarker discovery and clinical diagnostics. Dr. Zhang's primary research interests focus on developing more accurate, sensitive, and higher throughput measurement capabilities for biomolecules. His work centers on three main areas: Proteomics : Temporal plasma proteomics for Type 1 diabetes progression, cell-specific and spatial tissue proteomics, immunopeptidome analysis for novel T1D autoantigens, antimicrobial peptides, and glycated proteome in diabetic complications Lipidomics : Tissue-specific global lipidomics, high-resolution ozone-induced dissociation mass spectrometry, advanced analysis of glycosphingolipids, and lipid glycation in diabetes Metabolomics : Tryptophan catabolism, oxylipins and inflammation, fatty acid and energy metabolism, and chemical isotope labeling-based metabolomics Analysis of Dr. Zhang's recent publications (2022-2024) reveals a strong focus on translational biomedical applications, particularly in diabetes research and exercise physiology. His work demonstrates expertise in both method development (improved mass spectrometry techniques, data processing software) and biological applications (disease mechanisms, nutritional interventions). The research consistently bridges analytical chemistry with clinical applications, showing particular strength in spatial proteomics and lipidomics approaches. Dr. Zhang teaches advanced analytical chemistry courses including CHE 632/732 Advanced Analytical Chemistry, CHE 633/733 Bioanalytical Chemistry, and CHE 431/531 Instrumental Analysis. His laboratory is equipped with state-of-the-art instrumentation including Thermo QExactive HF, TSQ Quantiva, LTQ-Orbitrap with ETD, nano-LC and UPLC systems, and a Leco GC-TOF mass spectrometer. The Zhang Research Group currently includes four postdoctoral research fellows working across various aspects of proteomics, lipidomics, and metabolomics research.

• Neuroscience
• Diabetes
• Molecular Biology
• +۵ مورد دیگر

Sarah A Stanley, MBBCh, PhD is a faculty member at the Icahn School of Medicine at Mount Sinai, where she leads the Stanley Laboratory. Her research spans multiple disciplines at the intersection of neuroscience, diabetes, and molecular biology, with significant contributions to understanding the neuroendocrine regulation of metabolism. Education: BA, University of Cambridge BChir, University of Cambridge MB, University of Cambridge PhD, Imperial College, London University Dr. Stanley's research focuses on three primary areas: pioneering the use of radio waves and magnetic fields to stimulate individual cells and neurons (radiogenetics and magnetogenetics); developing nanoparticles in bioengineered murine models for preclinical applications; and advancing understanding of the interaction between central and peripheral systems in appetite control and diabetes. Her work represents a unique integration of engineering approaches with fundamental neuroscience and metabolic research. Her publications demonstrate a strong trajectory in neuroendocrine research with applications to diabetes treatment, showing increasing sophistication in techniques from molecular biology to advanced neural modulation approaches. The research shows particular strength in translating basic science discoveries into potential therapeutic applications. Scientific Awards: 2016 Alexander and Alexandrine Sinsheimer Scholar Award 2016 Dr. Harold and Golden Lamport Research Award 2015 Cell Symposia: Engineering the Brain International Travel Award Darwin Prize in Experimental Natural Sciences Arthur Burrows Prize (Dermatology) James Anderson Prize (Medicine and Surgery) Dr. Stanley's laboratory is currently funded by The National Institutes of Health and American Diabetes Association, working in close collaboration with colleagues across Mount Sinai and partnerships with Professor Jeffrey Friedman at Rockefeller University and Professor Jonathan Dordick at Rensselaer Polytechnic Institute. Her research program demonstrates strong institutional support and strategic collaborations that enhance the impact of her work. The Stanley Laboratory operates across multiple facilities at Mount Sinai, including locations in the Annenberg Building and Atran Berg Laboratory Building, reflecting the interdisciplinary nature of her research that bridges neuroscience, engineering, and metabolic medicine.

Jesse R. Dixonمشاهده پروفایل

دانشیار

• Chromatin structure
• 3D genome organization
• Gene regulation
• +۴ مورد دیگر

Jesse R. Dixon, M.D., Ph.D., is an Associate Professor at the Gene Expression Laboratory of the Salk Institute for Biological Studies in La Jolla, California. His research explores 3D genome architecture, chromatin organization, and gene regulation mechanisms, with implications for cancer and developmental disorders. He employs cutting-edge genomic technologies like Hi-C and single-cell multi-omics to investigate how chromosomal rearrangements impact gene expression. Dr. Dixon's work focuses on: Topological Domains (TADs) and their role in enhancer-promoter communication Haplotype phasing using chromatin conformation data Structural variant-driven oncogene activation in cancer Single-cell mapping of chromatin and DNA methylation dynamics His publications consistently demonstrate innovations in 3D genome analysis, particularly in neurobiology and oncology contexts, with recurring themes of chromatin topology, epigenetic regulation, and computational genomics. Awards & Honors: Pew Biomedical Scholar (2024) Helmsley Salk Fellow He mentors graduate and postdoctoral researchers in genomics and computational biology, with current projects on chromatin dynamics in cancer and development. The Dixon Lab actively develops novel methodologies for studying genome architecture.

Daniel Jeffaresمشاهده پروفایل

مدرس ارشد

• Leishmania Genomics
• Population Genetics
• Quantitative Genetics
• +۳ مورد دیگر

Dr. Daniel Jeffares is a Senior Lecturer in the Department of Biology at the University of York. His research focuses on Leishmania genomics, population genetics, and quantitative genetics, with an emphasis on understanding evolutionary processes and molecular biology in parasitic organisms. His work contributes to global health initiatives, including collaborations through the UK-Brazil Joint Centre Partnership in Leishmaniasis (JCPiLeish) and the PREV_PKDL project analyzing visceral leishmaniasis in East Africa. He leads the Jeffares Lab, which utilizes advanced genomic techniques to study parasite evolution and pathogenesis. Research Interests: Leishmania population genomics and drug resistance Genomic analysis of co-infections and pathogen diversity Evolutionary adaptations in trypanosomatids and extremophiles Applications of genomic methods in disease research Awards : Recipient of the Visiting Professorship (2022), recognizing his contributions to collaborative research and capacity-building in genomic methodologies. Grants & Collaborations: Principal Investigator on projects funded by MRC, Wellcome Trust, and NERC Leadership in multidisciplinary initiatives addressing visceral leishmaniasis in Sudan, Ethiopia, Uganda, and Kenya Active partnerships with institutions in Brazil and global health networks Labs/Teams: The Jeffares Lab at the University of York, part of the Biology Department’s research cluster focusing on microbial genomics and evolutionary processes.

Michael Landisمشاهده پروفایل

استادیار

• Phylogenetic Biogeography
• Evolutionary Modeling
• Comparative Methods
• +۲ مورد دیگر

Michael Landis is Assistant Professor of Biology at Washington University in St. Louis, developing statistical models and computational tools to reconstruct evolutionary patterns. Research integrates phylogenetics, biogeography, and trait evolution to study historical biodiversity dynamics across deep timescales. Key research areas: Developing Bayesian methods for phylogenetic biogeography Modeling biome shifts and diversification patterns Creating open-source software for evolutionary analysis (RevBayes, phyddle) Reconstructing ancestral networks for pierid butterflies Recent work includes novel approaches for state-dependent diversification modeling, deep learning applications in phylogenetics, and global-scale analyses of butterfly evolution. The lab emphasizes collaborative software development and evolutionary hypothesis testing.

Jue Chenمشاهده پروفایل

استاد

• Structural Biology
• Membrane Proteins
• ABC Transporters
• +۷ مورد دیگر

Jue Chen is the William E. Ford Professor at The Rockefeller University and an Investigator of the Howard Hughes Medical Institute. His research focuses on the structural and functional mechanisms of membrane transport proteins, particularly ATP-binding cassette (ABC) transporters and the cystic fibrosis transmembrane conductance regulator (CFTR). He employs structural biology techniques like X-ray crystallography and cryo-electron microscopy to study these proteins' roles in health and disease, including drug resistance, cancer, and cystic fibrosis. Education: B.Sc. in Chemistry, Ohio University (1993) Ph.D. in Biochemistry, Harvard University (1998) Research Interests: ABC transporter structure-function relationships Mechanisms of multidrug resistance in cancer CFTR dysfunction in cystic fibrosis Development of small-molecule therapeutics targeting membrane proteins Awards: Pew Biomedical Scholar (2003) Anatrace Membrane Protein Award (2018) Labs & Teams: Laboratory of Membrane Biology and Biophysics at Rockefeller University, collaborating with interdisciplinary teams in chemical biology and structural biology.

Jane Parkerمشاهده پروفایل

دانشیار

• Plant innate immunity
• Host-microbe interactions
• NLR receptor signalling
• +۶ مورد دیگر

Jane Parker is an Associate Professor at the Institute for Genetics, University of Cologne. She has held prestigious positions including Max-Planck Fellow (2004-2009) and Senior Group Leader at the Max-Planck Institute for Plant Breeding Research. Her career spans institutions like the Sainsbury Laboratory and John Innes Centre, focusing on plant-microbe interactions. Education: BSc in Applied Biology (1st class hons, 1983) from University of Bradford, PhD in Botany/Microbiology (1987) from University of Wales, Swansea. Her research centers on plant innate immunity, NLR receptor signaling, and biotic stress networks. She investigates how plants reprogram transcription during pathogen attacks and studies natural variation in defense mechanisms using Arabidopsis. Jane has received significant recognition, including election to EMBO and the Leopoldina Academy. She serves on editorial boards for Science , Current Opinion in Plant Biology , and Trends in Plant Science . Her leadership roles include co-coordinating the CEPLAS Cluster of Excellence (2013-2018) and reviewing grants for major international funding bodies.

Giulia De Lorenzoمشاهده پروفایل

استاد

• Plant immunity
• Plant-pathogen interactions
• Molecular recognition
• +۵ مورد دیگر

Giulia De Lorenzo is a Full Professor of Plant Physiology at Sapienza University of Rome since 2000, with prior roles as Associate Professor at Sapienza University of Rome (1994-1999) and University of Bari (1991-1994). Her research focuses on plant immunity, molecular recognition, and cell wall dynamics, particularly in plant-pathogen interactions involving damage-associated molecular patterns (DAMPs) and their role in signal transduction. Education: Laurea in Biology (1980, Sapienza University of Rome, cum laude), PhD in Evolutionary Biology (1987, Sapienza University of Rome) Her work explores the structural and functional basis of plant defense mechanisms, including the inhibition of cell wall-degrading enzymes and engineering plant resistance through chimeric receptors. Articles highlight her contributions to understanding DAMPs, PGIP proteins, and their applications in crop protection and bioconversion. Notable scientific awards include the 2011 Sapienza University of Rome Award for Excellence in Research , 1997 Giovanni Armenise-Harvard Foundation Award , and the 1983 Fondazione V.V. Landi Award from the Accademia dei Lincei. She has served on editorial boards and organized international conferences in plant science.

Matthew R. Dentمشاهده پروفایل

استادیار

• Protein biochemistry
• Biophysical techniques
• Bioinorganic chemistry
• +۴ مورد دیگر

Matthew R. Dent is an Assistant Professor in the Department of Chemistry at Wayne State University’s College of Liberal Arts and Sciences. His research focuses on protein biochemistry, biophysical and bioinorganic techniques, and drug design. He holds a B.S. from James Madison University (2014), a Ph.D. in Chemistry from the University of Wisconsin–Madison (2019), and completed an NIH Postdoctoral Fellowship at the University of Pittsburgh (2019–2024). B.S., James Madison University, 2014 Ph.D. in Chemistry, University of Wisconsin–Madison, 2019 NIH Postdoctoral Research Fellow, University of Pittsburgh, 2019–2024 His research interests center on protein biochemistry, leveraging biophysical and bioinorganic methodologies, chemical computation, and bioinformatics. He investigates animal models of disease and drug design, particularly developing CO-sensing hemoproteins for medical applications and exploring heme-dependent signaling pathways in cellular contexts. Notable grants include NIH K99/R00 awards for optimizing hemoprotein-based CO antidotes and biosensors. His NIH postdoctoral fellowship supported studies on heme proteins and their medical applications. Additional grants focus on oxygen carrier development for hemorrhagic shock resuscitation. Though specific advisees are not listed, his research involves interdisciplinary collaborations. Grants emphasize CO poisoning treatments and oxygen delivery systems. His work bridges biochemistry, pharmacology, and medical applications. Labs or teams are not explicitly detailed in the provided information.

• Nematology
• Virology
• Genetics
• +۳ مورد دیگر

Dr. Lisa van Sluijs is an Assistant Professor at the Laboratory of Nematology within the Plant Research International (PE&RC) at Wageningen University & Research. Her research focuses on nematology, virology, and genetics, particularly in the context of Caenorhabditis elegans. She has published extensively on topics including nematode-virus interactions, genetic variation in disease susceptibility, and the ecological implications of microbial communities. Key Research Areas: Nematode biology, viral pathogenesis, genetic mapping, and ecological dynamics. Affiliations: Co-promotor in multiple PhD projects, including studies on plant-parasitic nematodes and C. elegans ethanol responses. Notable Awards: Best presentation Zoology (2017), Thesis cover price (2020), and Travel Award ICN (2020). Her work bridges fundamental biology with applied research, addressing questions about host-pathogen interactions, population genetics, and environmental microbiology. She actively participates in conferences and organizes events like the TE-NEM Symposium, contributing to scientific outreach and collaboration.

• Immunology
• Virology
• Infectious Diseases
• +۳ مورد دیگر

Steven Erickson is a Research Fellow at Yale University, affiliated with the Yale School of Medicine. His research focuses on immunology, particularly the role of immunoglobulins in viral and bacterial interactions within the gut, B cell development, and antibody responses to emerging pathogens like SARS-CoV-2. His work spans mechanisms of immune homeostasis, IgA regulation, and the interplay between gut microbiota and viral pathogenesis. Research interests include viral immunity, B cell receptor editing, and genetic factors shaping immunoglobulin diversity. His studies on SARS-CoV-2 variants have advanced understanding of antibody neutralization and vaccine design. Erickson's contributions bridge molecular immunology, virology, and microbiology to address infectious disease challenges. Recent publications highlight antibody responses to SARS-CoV-2 variants, IgE induction by glucocorticoids, and gut microbiota's role in retroviral pathogenesis. His work has implications for developing therapies targeting viral infections and autoimmune conditions. No scientific awards or grants are explicitly mentioned in the provided text. No advised students are listed.

Rui Guoمشاهده پروفایل

استادیار

• Epstein-Barr Virus (EBV) Pathogenesis
• Viral Oncology
• Cancer Metabolism
• +۵ مورد دیگر

Rui Guo is an Assistant Professor at Tufts University School of Medicine, affiliated with the Department of Molecular Biology and Microbiology. Their research focuses on Epstein-Barr Virus (EBV) pathogenesis, particularly its role in cancers like Burkitt lymphoma and mechanisms for developing targeted therapies. Doctor of Philosophy (2018), Kansas State University Master of Science (2013) and Bachelor of Science (2010), Yangzhou University Research interests include EBV-driven metabolic vulnerabilities in B-cells, with a focus on methyl group metabolism, mitochondrial remodeling, and lipid dynamics. Their work aims to improve cancer treatments by targeting viral dependencies. Recent publications highlight discoveries in EBV's manipulation of cardiolipin synthesis , methionine metabolism , and lysosomal iron reduction in Burkitt lymphoma. Techniques include transcriptomics , metabolomics , and CRISPR/Cas9 screening . Scientific recognition includes: National Institutes of Health Grant (2022-2026) for Epstein-Barr Virus epigenetic research

Sharon Kesslerمشاهده پروفایل

مدرس

• Disease Ecology
• Animal Cognition
• One Health
• +۷ مورد دیگر

Dr. Sharon Kessler is a Lecturer in Psychology at the University of Stirling's Faculty of Natural Sciences. She holds a PhD from Arizona State University (2014) and completed postdoctoral fellowships in computational modeling (McGill University), virology (Leibniz Institute), and disease signaling (Durham University). Her research integrates disease ecology and animal cognition, emphasizing the One Health framework to study how animal health perceptions influence disease transmission dynamics. Key interests include the evolution of human healthcare networks, behavioral defenses against pathogens, and conservation biology. Education: PhD, Arizona State University, 2014 Postdoctoral Fellowships: McGill University (Canada), Leibniz Institute (Germany), Durham University (UK) Research Interests: Role of cognition in disease avoidance behaviors Evolution of human care-giving strategies Parasite-microbiome interactions in lemurs Zoonotic disease surveillance Social structures and health signaling in primates Collaborations: Royal Zoological Society of Scotland Behavior and Evolution Research Group Cognition in Complex Environments Initiative Advising: Open to mentoring students on topics like healthcare networks, primate behavior, or conservation genetics. Contact via email for project discussions.