جستجوی استاد راهنمای دانشگاهی

Colm Nestorمشاهده پروفایل

دانشیار

• Epigenetic Control of Human T-cell Biology
• Autoimmunity and Allergy
• Cancer (Hematology and Other Tumors)
• +۳ مورد دیگر

Colm Nestor is a Senior Associate Professor at Linköping University, Sweden, affiliated with the Faculty of Medicine and Health Sciences, Department of Biomedical and Clinical Sciences, and the Division of Children's and Women's Health. His research focuses on epigenetic control of T-cell biology, sex differences in disease susceptibility, and developing therapies targeting DNA methylation. He holds leadership roles including Chair of the Junior Faculty Club, Co-Chair of the Centre for Personalised Medicine, and Member of the Academic Employment Board. Education highlights include a B.A. in Natural Sciences from Trinity College Dublin, followed by M.Sc. degrees in Computer Science (University of Cork) and Bioinformatics (University of York). He earned his Ph.D. in 2003 from the University of Glasgow. Postdoctoral training includes roles at the University of Edinburgh and Linköping University, alongside industry experience as a Bioinformatics Specialist at DeCODE Genetics and a Database Developer at LION Biosciences. Research interests center on understanding how the X-chromosome and DNA methylation influence health, particularly in autoimmune diseases, infections, and cancers like childhood leukemia. He investigates sex-specific disease mechanisms and leverages systems medicine to identify diagnostic/therapeutic targets. His work also addresses methodological flaws in epigenetic research, such as the widely used DIP-seq method. Recognized with prestigious awards: the 2025 Onkel Adam Prize and an ERC Consolidator Grant (2020) for sex-bias research. He also received funding from the Joanna Cocozza Foundation for pediatric medicine studies. Current projects include studying TET2 reactivation in leukemia and epigenetic changes in pregnancy-related T-cell dysfunction. Nestor advises four PhD students and collaborates with researchers like Huan Zhang (Principal Research Engineer) and Antonio Lentini (Researcher). He contributes to teaching at the Medical Program, Experimental Biosciences M.Sc., and Ph.D. courses. His lab, The Nestor Lab , integrates epigenetic, genomic, and computational approaches for clinical impact.

• Economic Evaluations
• Non Communicable Diseases
• Adolescent Health and Wellbeing
• +۴ مورد دیگر

Neelam Kalita is a Senior Research Fellow in Healthcare Modelling at Southampton Health Technology Assessments Centre (SHTAC), University of Southampton. She specializes in economic evaluations of health technologies and contributes to evidence reviews for NICE programs, spanning oncology, retinal conditions, and public health interventions. Her primary research focus includes adolescent health, non-communicable diseases, and global health equity. Her work history includes roles at a pharmaceutical consultancy firm and as a research assistant at the School of Health and Related Research (ScHARR), University of Sheffield. She collaborates with the MRC LEU on behavioral interventions to improve adolescent health outcomes. Neelam is affiliated with several University of Southampton campuses, including Highfield Campus and University Hospital Southampton. Neelam’s research publications (2021–2023) emphasize cost-effectiveness analyses of treatments for ulcerative colitis, multiple myeloma, uterine fibroids, and other conditions. These studies often intersect with pharmacoeconomics, gene therapy, and rare disease interventions. Her teaching contributions include the module MEDI6233: Health Economics for Public Health and training courses on health economics through SHTAC. No scientific awards are listed in her profile. She has supervised no formally registered PhD students, though her NIHR Pre-Doctoral Fellowship (2019–2021) funded £60,462 demonstrates prior research engagement. Current projects include the Engaging Adolescents in Changing Behaviour (EACH-B) initiative. Neelam is part of interdisciplinary research teams at SHTAC and collaborates with external groups like MRC LEU to advance healthcare modelling and global health strategies.

• Gastrointestinal Oncology
• Cancer Pathogenesis
• Metastasis Biology
• +۴ مورد دیگر

Dr. Sandra D Algaze is a Clinical Assistant Professor at the Keck School of Medicine of USC, specializing in Gastrointestinal Oncology within the Division of Medical Oncology. With clinical expertise in colorectal cancer and research focus on cancer pathogenesis , metastasis biology , and treatment resistance , she combines molecular profiling with clinical applications. Completed Internal Medicine residency at University of Miami Clinical Fellowship in Hematology/Oncology at USC/Los Angeles County Hospital Chief Fellow during fellowship training Research Highlights: • Novel pathways in gastrointestinal tumor biology • Biomarker discovery for treatment response prediction • Addressing healthcare disparities in cancer clinical trials • Investigating neurotransmitter signaling in cancer progression Scientific Contributions: Her 15+ publications span from 2017 to 2025, focusing on molecular markers (MCL-1, CD47, TROP2), chemokine signaling, and translational oncology. The Winn CDA award reflects her commitment to diversity in clinical trials. Her work bridges basic science with geriatric oncology applications.

• Pediatrics
• Endocrinology
• Type 1 Diabetes
• +۴ مورد دیگر

Roshanak Monzavi, MD is a Clinical Professor of Pediatrics at the University of Southern California (USC), affiliated with Children’s Hospital Los Angeles (CHLA). Her clinical and research focus centers on pediatric endocrinology, particularly type 1 diabetes management, health-related quality of life assessment, and clinical trials evaluating interventions for metabolic disorders. She specializes in advancing patient-centered outcomes research through innovative measurement tools like the Type 1 Diabetes and Life (T1DAL) measures. Her work emphasizes translational research in immunotherapy for new-onset type 1 diabetes, including trials with alefacept and abatacept. She has also investigated the role of continuous glucose monitoring (CGM) in improving glycemic control among adolescents and young adults, demonstrating durable benefits over 12 months. Additional research interests include pediatric endocrine conditions such as congenital adrenal hyperplasia and metabolic syndrome. Dr. Monzavi’s contributions span over two decades, with publications addressing vitamin D’s impact on diabetes, caregiver burden in type 1 diabetes families, and conference highlights from major endocrine meetings. Her research integrates clinical care innovations with rigorous psychometric validation of patient-reported outcome measures. Her advising and grant activities include involvement in NIH-funded clinical trials and collaborative efforts with the Clinical and Translational Science Institute (CTSI). Though no specific awards are listed, her sustained publication record reflects ongoing contributions to pediatric endocrinology and diabetes care advancements. She actively participates in academic conferences, ensuring clinical practice aligns with emerging research.

• Kidney Physiology
• Renal Pathophysiology
• V-ATPase Regulation
• +۳ مورد دیگر

Nuria Maria Pastor-Soler, MD, PhD, FASN, is an Associate Professor of Medicine and Assistant Dean for Research Mentoring at the Keck School of Medicine of the University of Southern California (USC). She also serves as the Associate Vice Chair for Faculty Development and Director of the Required Scholarly Project Program. Her research focuses on kidney acid-base homeostasis, vacuolar proton ATPase (V-ATPase) regulation, and renal transport mechanisms. Key interests include metabolic pathways in chronic kidney disease and renal cell carcinoma biomarker discovery. Dr. Pastor-Soler earned her MD from Jefferson Medical College and a PhD in Biochemistry and Molecular Biology from Thomas Jefferson University. She completed her Nephrology Fellowship at Brigham and Women’s/Massachusetts General Hospital. Her research explores V-ATPase in kidney and male reproductive tract physiology, sodium transport regulation via bicarbonate-sensitive adenylyl cyclase (sAC), and WNK kinase signaling in salt transport. She investigates how acidosis impacts renal metabolism in CKD progression and seeks clinical biomarkers for renal carcinoma. Notable awards include the American Heart Association’s Council for the Kidney in Cardiovascular Disease Chair (2016), American Physiological Society Young Investigator Award (2012), and Claflin Distinguished Scholar Award (2005). Her work spans over 70 peer-reviewed publications, emphasizing kidney organoid engineering, drug delivery systems for polycystic kidney disease, and AMP-activated protein kinase (AMPK) signaling in renal health. Dr. Pastor-Soler mentors trainees through the Required Scholarly Project Program and holds leadership roles in professional societies. Her lab integrates ex vivo kidney slices, cell cultures, and organoids to model renal pathophysiology and test therapeutic strategies.

• Potassium Homeostasis
• Metabolic Syndrome
• Gut-Brain Axis
• +۳ مورد دیگر

Jang-Hyun Youn is an Associate Professor at the Keck School of Medicine, University of Southern California , specializing in Physiology & Neuroscience . His research focuses on potassium homeostasis , metabolic syndrome , and free fatty acid interactions , with recent work exploring green tea extracts and citrus compounds for sleep regulation . Current affiliation: Keck School of Medicine, USC Email: youn@usc.edu Research trends span nutritional physiology , ion transport modeling , and gut-liver-brain interactions , including stable isotope tracing of potassium fluxes and lipid mediator analysis in metabolic disorders.

• Neuroscience
• Molecular Biology
• Neurodegenerative Diseases
• +۴ مورد دیگر

Professor Peter McCaffery holds a Personal Chair at the University of Aberdeen's Institute of Medical Sciences within the School of Medicine, Medical Sciences and Nutrition. His research focuses on retinoic acid's role in the brain, particularly neurodegenerative diseases like Alzheimer's and ALS. He leads a lab exploring vitamin A's neuroprotective potential, synthetic retinoid development, and hypothalamic regulation of retinoid homeostasis. McCaffery has supervised numerous students and postdocs, including Azita Kouchmeshky (neurodegenerative therapeutics) and Thabat Khatib (neuroplasticity). He teaches courses in biochemistry and molecular pharmacology. Key collaborators include Bill Blaner (Columbia University) and Andy Whiting (Durham University). His work is funded by Wellcome Trust, BBSRC, and others. McCaffery has published over 90 articles with an h-index of 54, emphasizing retinoid signaling in cognition, cannabinoid interactions, and translational neuroscience. His lab developed the RAR-M DC645 compound for ALS treatment, demonstrating neuroprotective effects in motor neuron models.

Karen Ryanمشاهده پروفایل

استاد

• Neuroendocrinology
• Metabolic Regulation
• Stress Physiology
• +۴ مورد دیگر

Karen Ryan is a Professor in the Department of Neurobiology, Physiology and Behavior at the University of California, Davis. Her research focuses on the neuroendocrine and metabolic adaptations to environmental challenges, particularly stress, dietary changes, and sex differences in metabolic regulation. She investigates hormonal pathways like FGF21 and the hypothalamic-pituitary-adrenal (HPA) axis, exploring their roles in energy homeostasis, feeding behavior, and metabolic diseases. Research Interests: Ryan's work spans neuroendocrinology, metabolic regulation, and the physiological consequences of dietary manipulations. Key areas include FGF21 signaling in nutrient sensing, sex-dependent metabolic responses to bariatric surgeries, and the interplay between stress hormones and cardiometabolic health. Her studies often use rodent models to dissect molecular mechanisms in vivo. Publications Overview: Her recent work highlights FGF21's role in modulating dietary preferences, stress responses, and metabolic outcomes post-bariatric surgery. Articles emphasize sex-specific effects, interorgan crosstalk, and the physiological implications of protein restriction or ketosis-inducing diets. Labs & Collaborations: Ryan's lab focuses on translational research linking basic metabolic mechanisms to clinical applications. Collaborations involve endocrinology, nutrition science, and systems biology approaches to address obesity, metabolic syndrome, and stress-related disorders.

• Immunology
• Autoimmune Diseases
• Inflammation Research
• +۳ مورد دیگر

Huapeng Fan is an Adjunct Research Fellow and Research Assistant at Monash University's Faculty of Medicine, Nursing and Health Sciences, affiliated with the Centre for Inflammatory Disease. His research focuses on inflammation mechanisms, autoimmune diseases, and molecular pathways involved in conditions like rheumatoid arthritis and systemic lupus erythematosus. Key topics include macrophage migration inhibitory factor (MIF), NLRP3 inflammasome regulation, autophagy, and glucocorticoid sensitivity. His work contributes to UN Sustainable Development Goals related to health and well-being. Research interests span immunology, molecular biology, and pharmacology, with emphasis on inflammatory mediators, cytokine regulation, and therapeutic targets. Notable studies explore MIF's role in inflammation, GILZ's anti-inflammatory effects, and formyl peptide receptor agonists for arthritis treatment. His publications (19 total) span 2005–2019, covering topics like gene expression in autoimmune diseases, IL-1 dependent disorders, and angiogenesis inhibitors derived from decorin proteins. His articles have been cited over 250 times and referenced in patents and Wikipedia. He collaborates widely, including with Prof. Morand and Harris, and his work has been picked up by 19 news outlets and featured on social media platforms. No formal student advisement or awards are explicitly stated, though his research has significant industry and academic impact.

• Nephrology
• Chronic Kidney Disease
• Dialysis
• +۷ مورد دیگر

Prof. Lawrence McMahon is a Professor at the Eastern Health Clinical School, Monash University, specializing in nephrology and renal medicine. His research focuses on chronic kidney disease (CKD), dialysis optimization, endothelial dysfunction, and sarcopenia in end-stage renal disease patients. He has led major projects including National Health and Medical Research Council (NHMRC)-funded studies on cell sorting equipment and combined exercise-psychological therapy interventions. His work spans over two decades with 78+ publications, emphasizing clinical trials, biomarker discovery, and patient-centered outcomes. Research Interests: - Nephrology & Dialysis Innovations - Endothelial Glycocalyx Damage Mechanisms - Sarcopenia and Frailty in CKD - Peritoneal Dialysis Complications - Cardiac Health in Renal Patients Key Contributions: - Developed ANCA renal risk prediction models - Pioneered incremental peritoneal dialysis protocols - Investigated FGF23's role in muscle wasting - Advanced advance care planning frameworks for dialysis patients Grants/Projects: - NHMRC Equipment Grant (2014-2015) for cell sorting technology - Primary Investigator for exercise-therapy quality of life study (2010)

Chrishan Samuelمشاهده پروفایل

استاد

• Fibrosis
• Cardiovascular Disease
• Kidney Disease
• +۳ مورد دیگر

Chrishan Samuel is a Professor and Head of the Fibrosis Laboratory in the Department of Pharmacology at Monash University. He holds a position as a Monash Biomedicine Discovery Fellow. His research focuses on identifying novel therapeutic targets for fibrosis prevention in cardiovascular, renal, and allergic airways diseases, with a primary interest in the anti-fibrotic potential of relaxin and other anti-fibrotic agents. Samuel leads projects investigating combination therapies for tissue repair and collaborates on studies involving nanoparticle drug delivery and placental inflammation in preeclampsia. Samuel's expertise aligns with UN Sustainable Development Goals related to good health and well-being. His work spans collaborations across multiple institutions, including the Victorian Heart Institute. Key research areas include fibrosis mechanisms, stem cell biology, and translational therapies. Recent projects include developing engineered mesenchymal stromal cells for chronic kidney disease and evaluating nanoparticle toxicity in drug delivery systems. His research output includes peer-reviewed articles on topics such as angiotensin receptor crosstalk, Wnt/β-catenin signaling, and relaxin's role in cardiac fibrosis. He actively engages in grants and partnerships, exemplified by projects funded by Aus Bio Limited and Ferring Innovation Grants. Samuel's lab explores cutting-edge methods like second-harmonic generation imaging for fibrosis assessment and combines cell therapies with anti-fibrotic drugs for enhanced efficacy.

Michael Burmanمشاهده پروفایل

استاد

• Neuroscience
• Behavioral Neuroscience
• Psychology
• +۳ مورد دیگر

Michael Burman is a Professor of Psychology at the University of Maine, affiliated with the School of Social and Behavioral Sciences. He holds roles as COBRE Academic Director and Project Leader. His education includes a B.A. from Carleton College (2001) and a Ph.D. in Behavioral Neuroscience from the University of Minnesota (2006), followed by postdoctoral training at the University of Delaware (Newark). Research Interests: Dr. Burman's lab focuses on the neurological substrates of fear, anxiety, and learning in rodents , particularly memory components in anxiety disorders like phobias and PTSD. Current work includes modeling pediatric anxiety. Techniques employed span Stereotaxic surgery Pharmacology Immunohistochemistry PCR Grant Activity: He led a $404,000 NIH (NIMH) grant (2012–2015) assessing hippocampus-amygdala interactions in emotional learning. This work aligns with his broader focus on developmental neuroscience and translational models of anxiety. Advising & Outreach: While no formal advisees are listed, Dr. Burman has contributed to educational outreach via K-12 neuroscience programs. His research bridges behavioral and molecular neuroscience, emphasizing early life experiences' impact on adult emotional processing. Labs/Teams: His lab integrates behavioral analysis with neurobiological techniques, collaborating with institutions like the University of Delaware and the University of Minnesota. Key projects involve rodent models of PTSD and pediatric anxiety, leveraging pharmacological interventions and developmental approaches.

Dilara Perverمشاهده پروفایل

مدرس

• Hematology
• Biomedical Engineering
• Stem Cell Biology
• +۵ مورد دیگر

Dr. Dilara Perver is a Lecturer and Jr. Group Leader at ETH Zürich, affiliated with the Department of Health Sciences and Technology and the Institute of Translational Medicine. She holds a Dr. Sc. ETH Zürich, complemented by M.Sc. degrees in Biology and Chemistry from Hacettepe University (Turkey). Her research focuses on ex-vivo technologies for immuno-cellular therapies targeting hematological malignancies, predictive microphysiological models for leukemia/lymphoma, and development of bioreactors for stem cell expansion. She has authored numerous peer-reviewed articles and book chapters, with a particular emphasis on bone marrow niche engineering and extracellular matrix dynamics. Key professional milestones include a postdoctoral role at ETH Zürich, an internship at Novartis in CAR-T cell therapy development, and leadership roles in academic associations like AVETH and the Scientific Staff Association of Health Sciences and Technology. She has secured grants such as the TÜBİTAK Doctoral Research Grant (USD 120,000) and the National Graduate Student Prestige Scholarship. Her work bridges biomaterials, stem cell biology, and clinical translation, with implications for regenerative medicine and oncology. Dr. Perver is actively involved in teaching and science communication, having completed training in project management, entrepreneurship, and clinical trial design. Her contributions to interdisciplinary research and innovation are further highlighted by her memberships in societies like the International Society for Stem Cell Research (ISSCR) and the European Society for Blood and Marrow Transplantation (EBMT).

Lynda Harrisمشاهده پروفایل

دانشیار

• Placental Drug Delivery
• Nanomedicine
• Pregnancy Complications
• +۳ مورد دیگر

Lynda Harris, PhD, is an Associate Professor in Obstetrics and Gynaecology at the University of Nebraska Medical Center (UNMC), USA. Previously, she held roles including Senior Lecturer in Pharmaceutics at the University of Manchester (2018–2022), Research Director at the Division of Pharmacy and Optometry, and Scientific Co-Director of Tommy’s Maternal and Fetal Health Research Centre (2018–2022). Her research focuses on placental drug delivery and nanomedicine, addressing pregnancy complications like pre-eclampsia and fetal growth restriction. She has pioneered methods for affinity-based drug targeting using peptides, developing placenta-specific nanocarriers and therapeutics. Education: BSc (1st Class Hons) Pathobiology and PhD from the University of Reading (1999, 2003). Research interests include placental homing peptides, targeted drug delivery systems, and mechanisms regulating trophoblast function. Awards include the BBSRC David Phillips Fellowship (2010) and the Gábor Than Award (2010). Teaching roles include undergraduate MPharm program leadership and postgraduate supervision. She serves on editorial boards of Placenta and Molecular Medicine Reports , and mentors BBSRC Future Leader Fellows. Her work aligns with UN Sustainable Development Goals, particularly maternal and child health.

• Diabetic Cardiomyopathy
• Mitochondrial Metabolism
• Insulin Resistance
• +۳ مورد دیگر

E. Dale Abel is a Professor and Department Chair at the David Geffen School of Medicine, University of California Los Angeles (UCLA) . His work bridges cardiovascular research with metabolic disorders , focusing on diabetes-induced mitochondrial dysfunction and insulin signaling in cardiac health . Current research programs include modulating ROS via electromagnetic fields and mitochondrial dynamics in platelets . Education: MD and PhD in Molecular Medicine from University of Melbourne Training: Internship at Royal Melbourne Hospital; Fellowship at NIH His research interests center on diabetic cardiomyopathy , mitochondrial bioenergetics , and metabolic reprogramming in heart disease . Recent studies explore: 2024 Cell paper on evolving diabetes pandemic 2022 Circulation Research work on macrophage glucose suppression 2021 mitochondrial stress adaptation in Autophagy and eLife Scientific grants include: NIH R01HL157781 (2021-2025): Investigating MG53 in heart structure NIH R01DK125079 (2021-2026): Electromagnetic field therapy for diabetes NIH R01HL112413 (2015-2020): Cardiac insulin resistance mechanisms