معرفی
Karen Ryan is a Professor in the Department of Neurobiology, Physiology and Behavior at the University of California, Davis. Her research focuses on the neuroendocrine and metabolic adaptations to environmental challenges, particularly stress, dietary changes, and sex differences in metabolic regulation. She investigates hormonal pathways like FGF21 and the hypothalamic-pituitary-adrenal (HPA) axis, exploring their roles in energy homeostasis, feeding behavior, and metabolic diseases.
Research Interests: Ryan's work spans neuroendocrinology, metabolic regulation, and the physiological consequences of dietary manipulations. Key areas include FGF21 signaling in nutrient sensing, sex-dependent metabolic responses to bariatric surgeries, and the interplay between stress hormones and cardiometabolic health. Her studies often use rodent models to dissect molecular mechanisms in vivo.
Publications Overview: Her recent work highlights FGF21's role in modulating dietary preferences, stress responses, and metabolic outcomes post-bariatric surgery. Articles emphasize sex-specific effects, interorgan crosstalk, and the physiological implications of protein restriction or ketosis-inducing diets.
Labs & Collaborations: Ryan's lab focuses on translational research linking basic metabolic mechanisms to clinical applications. Collaborations involve endocrinology, nutrition science, and systems biology approaches to address obesity, metabolic syndrome, and stress-related disorders.
