جست‌وجوی استاد و پژوهشگر

Jason Robert Climerمشاهده پروفایل

استادیار

• Memory
• Forgetting
• Spatial Memory
• +۷ مورد دیگر

Jason Robert Climer is an Assistant Professor in the Department of Molecular and Integrative Physiology and the Neuroscience Program at the University of Illinois Urbana-Champaign, with additional affiliation at the Beckman Institute for Advanced Science and Technology. His research focuses on the neural mechanisms of memory acquisition, maintenance, and forgetting. Dr. Climer conducted doctoral research under Michael Hasselmo at Boston University studying spatial memory timing, followed by postdoctoral training with Daniel Dombeck at Northwestern University where he developed novel optical neuroscience techniques. The Climer Lab investigates how neural activity in the hippocampus encodes and evolves during memory formation and forgetting. Using two-photon calcium/glutamate imaging , virtual reality environments , and computational approaches , the lab examines memory at multiple scales—from individual neurons to neural networks. Key research areas include memory dynamics , adaptive forgetting , spatial navigation , and neural representation stability , with emphasis on how continual learning requires efficient forgetting mechanisms. Analysis of Dr. Climer's publications (2013-2025) reveals a trajectory from foundational studies of grid cell phase precession to cutting-edge investigations of multisensory memory representation. His work increasingly integrates in vivo imaging with computational modeling to track how hippocampal representations drift in stable environments, highlighting forgetting as an active neurobiological process rather than passive decay. No scientific awards are listed in the provided information. Dr. Climer actively recruits graduate students and postdocs for interdisciplinary research at the intersection of neuroscience, engineering, and computation. His lab's advanced methodology—including custom virtual reality systems and dual-channel neural imaging—indicates substantial grant support for projects exploring memory mechanisms across developmental and environmental contexts. Housed at the Beckman Institute (2355 Beckman Institute), the Climer Lab operates a multidisciplinary team utilizing two-photon microscopy, virtual reality arenas, and computational modeling. Collaborations with Northwestern University researchers (evident in co-authored publications) extend the lab's impact across neural coding and memory systems neuroscience.

Colin Saldanhaمشاهده پروفایل

استاد

• Neuroendocrinology
• Neuroplasticity
• Neuroscience
• +۳ مورد دیگر

Colin Saldanha is a Professor in the Department of Psychology at American University, focusing on neuroendocrinology, neuroplasticity, and estrogen signaling mechanisms in the brain. His research explores compartment-specific hormone synthesis and its impact on learning, memory, and neuroprotection. PhD in Biopsychology, Columbia University BA in Biology & Psychology, Gustavus Adolphus College Current research investigates synaptocrine signaling , where estrogen is synthesized in synaptic boutons and astroglia to regulate neural function. His work spans neuroinflammation, brain injury recovery, and avian behavioral endocrinology. Recent publications (2010-2011) analyze neurochemical pathways in songbirds, synaptic hormone delivery, and steroid assay methodologies. Trends include estrogen's role in neuroprotection , aggression-related neuroendocrinology , and avian cognitive studies . Scientific Recognition Hillman Award for Graduate Advising Nominee (2010) Stabler Award for Excellence in Teaching (2006) Libsch Early Career Research Award (2005) Lindback Foundation Minority Faculty Award (2003) Grants include NIH RO1 funding (2002-2013) for synaptic aromatase research and NSF support (2011-2013) for neuroendocrinology meetings. His lab trains graduate researchers like Kelli Duncan and Bradley Walters.

Tara LeGatesمشاهده پروفایل

استادیار

• Neuroscience
• Neuronal Circuit Plasticity
• Reward Behavior
• +۸ مورد دیگر

Tara LeGates is an Assistant Professor in the Department of Biological Sciences at the University of Maryland, Baltimore County (UMBC), where she leads an active research laboratory investigating the neural circuit mechanisms underlying reward, mood, and cognitive behaviors. She is affiliated with the Interdisciplinary Life Sciences Building and is a key member of the neuroscience community at UMBC. Education: B.S. in Behavioral Neuroscience, Rider University (2007) Ph.D. in Biology, Johns Hopkins University (2013) Postdoctoral Training, University of Maryland School of Medicine (2019) Her research focuses on how synaptic and circuit-level plasticity in the brain regulates complex behaviors, particularly those related to depression and psychiatric disorders. Using a combination of electrophysiology, in vivo imaging, and behavioral analysis in mouse models, her lab explores how neuronal circuits such as the hippocampus-nucleus accumbens pathway integrate information to modulate reward and affect. She also investigates the role of light and circadian rhythms in mood regulation, building on foundational work involving melanopsin-expressing neurons. The recent publications from her lab and collaborations reveal a strong trend in understanding synaptic mechanisms in depression, circadian control of behavior, and the neural basis of reward processing. Her work bridges molecular, cellular, and systems neuroscience, with implications for developing novel therapeutic strategies for mood disorders. Scientific Awards: No specific awards were listed in the provided text. Advising and Grants: Dr. LeGates mentors trainees in experimental design, hypothesis testing, and scientific communication. While current advisees are not listed, her lab is actively engaged in research supported by external funding, as evidenced by her publication record in top-tier journals. She emphasizes training the next generation of scientists through hands-on research and skill development. Labs and Research Teams: She leads the LeGates Lab, located on the 3rd floor of the Interdisciplinary Life Sciences Building at UMBC. The lab employs a multidisciplinary approach, integrating electrophysiology, imaging, and behavioral assays in mice. The team investigates how neuronal circuits integrate information to regulate behaviors related to depression, with a focus on synaptic communication and plasticity. The lab is active on social media (Instagram) and collaborates widely with experts in circadian biology, synaptic function, and psychiatric neuroscience.

• Age-related memory decline
• Synaptic plasticity
• Autophagy
• +۵ مورد دیگر

Prof. Dr. Stephan Sigrist leads a research group at the German Center for Neurodegenerative Diseases (DZNE), focusing on age-related memory decline (AMI). His work bridges synaptic plasticity , autophagy , and NPY signaling using Drosophila olfactory conditioning paradigms combined with genetic, cell biological, and rodent model approaches. Institution: German Center for Neurodegenerative Diseases (DZNE), Berlin Key Collaborations: Schmitz and Garner groups for rodent model studies Research interests center on mechanisms of synaptic aging and neurodegenerative disease pathways. His group investigates how autophagy intersects with synaptic plasticity through evolutionarily conserved NPY signaling, aiming to identify therapeutic targets for AMI. Current projects include cross-species analysis of presynaptic signaling in hippocampal synapses. Recent publications reveal spermidine's role in autophagy-mediated synaptic protection, showing how modulating presynaptic active zone scaffolds (Brp/bruchpilot protein) preserves learning efficacy during aging. Their work demonstrates that autophagy impairment phenocopies age-related synaptic changes, while NPY signaling elimination reproduces similar deficits in young animals. The group's findings position synaptic metaplasticity as a critical node for therapeutic interventions in neurodegeneration. Collaborative efforts with the Schmitz lab have characterized presynaptic signaling in rodent hippocampal synapses, expanding their mechanistic framework. Contact: stephan.sigrist@dzne.de

• Neuropharmacology
• Neuroscience
• Neurodegenerative Diseases
• +۸ مورد دیگر

Professor Keith Murphy is a leading academic at University College Dublin , affiliated with the School of Biomolecular and Biomedical Science and the Conway Institute . As head of the UCD Neurotherapeutics Research Group , he pioneers work on drug targets for neurological disorders. Professor of Neuropharmacology (2018–present) Co-Director, UCD Centre for Applied Neuroscience (2015–present) Theme Leader for Neuroscience Research (2011–present) His research spans drug addiction , schizophrenia , multiple sclerosis , and memory consolidation , utilizing animal models , in vivo gene editing , and proteomic analysis . Recent work on cocaine-induced neurodevelopmental damage and midkine's role in memory demonstrates his focus on synaptic plasticity mechanisms. Key scientific contributions include: 2006: Rafaelsen Scholarship for neuropharmacology research 2016: Discovery of REST as hypoxia-responsive repressor 2025: Groundbreaking prenatal cocaine organoid study As an educator , he coordinated modules like Advanced CNS Pharmacology and Professional Career Development , mentoring future biomedical scientists. Current grants include SFI funding (2024–2027) for GDF-15/GFRAL signaling research in neuroprotection.

Andreas Faissnerمشاهده پروفایل

استاد

• Neuroscience
• Molecular Neurobiology
• Cell Morphology
• +۵ مورد دیگر

Andreas Faissner serves as Professor at the Department of Cell Morphology and Molecular Neurobiology within the Faculty of Biology and Biotechnology at Ruhr University Bochum. His research centers on elucidating molecular and cellular mechanisms governing central nervous system development and pathology, with emphasis on extracellular matrix dynamics and neural stem cell biology. Research interests include: Biology of radial glia stem cells, motoneurons, glial progenitors, and stem cell niches during development and disease Neuron-glia interactions regulating axon growth, guidance, synaptogenesis, and synaptic plasticity Retinal stem cells for neural network integration and visual system repair Molecular analysis of extracellular matrix components (tenascin-C, CSPGs), receptor signaling (RhoA GTPases, Vav-proteins), and perineuronal nets in memory stabilization and neuropsychiatric disorders Analysis of his 2007-2024 publications reveals sustained investigation into extracellular matrix roles across neural development, synaptic organization, and disease models. Key themes include matrix-mediated stem cell regulation, perineuronal net functions in hippocampal networks, and therapeutic implications for multiple sclerosis, epilepsy, and neurodegeneration through matrix-targeted interventions. No scientific awards were documented in the source material. Details regarding student advising and grant funding were not specified in the provided information. Faissner leads a multidisciplinary research unit employing molecular/cellular tools, genetically modified animal models, proteomics, and transcriptomics to dissect neural extracellular matrix interactomes, with long-term goals of developing therapeutic strategies for neurological disorders.

Rune Engerمشاهده پروفایل

استاد

• Neuroscience
• Astrocyte-Neuron Interplay
• Brain Edema
• +۳ مورد دیگر

Rune Enger is a Professor of Neuroscience at the University of Oslo, affiliated with the Division of Anatomy, Department of Molecular Medicine, and the Institute of Basic Medical Sciences within the Faculty of Medicine. He leads the Institute's education program and specializes in astrocyte-neuron interactions, particularly in healthy and dysfunctional brain states. Enger's research focuses on aquaporin-4 polarization, cerebral edema, sleep dynamics, and Alzheimer’s disease modeling. His work combines experimental neuroscience with computational and imaging tools like RippleNet and Begonia pipelines. Education: Cand.med. (Medical Doctorate), University of Oslo, including a medical student research program. Postdoctoral training at Oslo University Hospital under Erlend Nagelhus. Academic roles include Head of Education at the Institute of Basic Medical Sciences since 2024. Research Interests: Astrocyte physiology, brain fluid dynamics, glial signaling in neurological disorders, and development of neuroimaging/analytical tools. Key findings include the role of aquaporin-4 in solute clearance and sleep-related astrocyte activity regulation. Publications: Over 25 peer-reviewed articles in journals like Nature Communications , Fluids and Barriers of the CNS , and Frontiers in Cellular Neuroscience . Collaborates widely with teams in Norway and internationally, focusing on glial cell biology and translational neuroscience.

• Neuroscience
• Psychiatry
• Neural Circuitry
• +۳ مورد دیگر

Dr. Alicia Y Che is an Assistant Professor of Psychiatry at Yale University's School of Medicine, affiliated with the Department of Psychiatry and the Center for Brain & Mind Health. She joined Yale in 2021 after postdoctoral training at Weill Cornell Medical College and NYU. Her research focuses on neural circuits underlying social behavior and psychiatric disorders like PTSD. She holds a PhD in Physiology and Neurobiology from the University of Connecticut (2014) and a BS in Biology, Physics, and Physical Chemistry from Pacific Lutheran University (2009). Her key research projects explore oxytocin's role in social touch development and circuit dysfunction in PTSD. She investigates how sensory experiences shape cortical circuits using advanced techniques like in vivo calcium imaging and genetic manipulation. Dr. Che leads the Che Lab, which integrates molecular, electrophysiological, and behavioral approaches to study neural circuitry. Awards: NARSAD Young Investigator Award (2020), K99/R00 Pathway to Independence Award (2019). Labs/Teams: Director of Graduate Admissions for the Interdepartmental Neuroscience Program, member of the Janeway Society and Wu Tsai Institute. Her work bridges developmental neurobiology and translational psychiatry, emphasizing circuit-level mechanisms in mental health disorders.

Dmitri Rusakovمشاهده پروفایل

استاد

• Synaptic Plasticity
• Neuroscience
• Astroglia in Neural Circuits
• +۳ مورد دیگر

Dmitri Rusakov is a Professor of Neuroscience at the Queen Square Institute of Neurology, University College London . His research focuses on synaptic plasticity, astroglial signaling, and neural network dynamics. He has held prestigious fellowships including Wellcome Trust Principal Research Fellowships (2013–now, 2018) and European Research Council Advanced Grant (2012). Rusakov pioneered studies on astrocyte-neuron interactions, glutamate dynamics, and calcium signaling in situ. Research Themes : Synaptic machinery, diffuse signaling beyond synapses, astroglial roles in neural circuits Key Techniques : Fluorescence imaging, computational modeling, electrodiffusion analysis Publication Trends : Over 15 years, his work emphasizes astrocyte signaling , synaptic glutamate dynamics , calcium homeostasis , and in silico modeling . He explores how astroglia modulate synaptic plasticity and neural rhythms through GABA waves, Ca2+ gradients, and membrane recycling. Recent articles address methodological challenges in fluorescence sensor calibration and neurovascular coupling. Scientific Awards All-Ukraine Young Physicists Olympiad First Prize (1976, 1977) Medical Research Council UK Career Development Award (1999) Wellcome Trust Senior Research Fellowship (2003, 2008) Academia Europaea membership (2012) ERC Advanced Grant (2012) Wellcome Trust Principal Research Fellowship (2013, 2018) Collaborations span institutions including PNAS USA, Neuron, Nature, and Science journals. His career spans roles at UCL, Open University, Bogomoletz Institute, and international visiting positions.

Carlos Bas Orthمشاهده پروفایل

استاد

• Metabolic Plasticity
• Neuronal Energy Metabolism
• Neuroprotection
• +۴ مورد دیگر

Prof. Dr. Carlos Bas Orth is a Professor at the Institute for Clinical Neuroanatomy, part of the NeuroScienceCenter at Goethe University Frankfurt in Germany. His laboratory is located at Haus 89, Heinrich Hoffmann Str. 7, 60528 Frankfurt am Main, with contact via phone (+49 (0)69 6301-6916) and email. His research investigates how synaptic activity triggers neuronal adaptations through gene expression changes. Specific interests include: Metabolic plasticity mechanisms linking neuronal activity to energy metabolism Activity-dependent transcriptional control of mitochondrial stress resistance Disruptions in metabolic pathways during aging and neurological disorders Neuroprotective adaptations through synaptic-to-nuclear signaling Methodologically, his team employs multiparametric live imaging (tracking Ca 2+ , mitochondrial redox status, ATP levels), molecular biology techniques (qRT-PCR, spatial transcriptomics), biochemical metabolic assays, viral gene transfer, and neuroinflammation models using hippocampal neurons and brain slices. His publications consistently explore mitochondrial function, calcium signaling dynamics, and activity-dependent metabolic reprogramming in neurons, with recent work emphasizing therapeutic targeting of metabolic pathways.

Laura Andreaeمشاهده پروفایل

استاد

• Developmental Neuroscience
• Synapse Formation
• Neurodevelopmental Disorders
• +۴ مورد دیگر

Professor Laura Andreae holds the position of Professor of Developmental Neuroscience at King's College London, affiliated with the Department of Anatomy, the Centre for Developmental Neurobiology, and the School of Neuroscience. She leads the PhD programme in the MRC Centre for Neurodevelopmental Disorders. Her research focuses on synaptic development, neurodevelopmental disorders (e.g., autism, epilepsy, schizophrenia), and employs electrophysiology and imaging techniques. Key collaborators include Professors Juan Burrone, Declan Murphy, Grainne McAlonan, and Albert Basson. Education: MBBS (UCL, 1995), PhD (King's College London, 2004), BA (University of Cambridge, 1992). Research Interests: Synaptic connectivity, neural circuit formation, and disruptions in neurodevelopmental disorders. She investigates how neuronal activity regulates synapse formation and explores genetic models of autism and schizophrenia. Awards and Grants: Leverhulme Trust Research Project Grant (2024), BBSRC grant (2024), Louise Hanson Marshall Special Recognition Award (2023), and a Wellcome Discovery Award (2023). Projects include studying gene regulation in autism and Alzheimer's, and neuronal development mechanisms. Labs/Teams: Active in the Centre for Developmental Neurobiology and collaborates across multiple institutes within King's College London.

• Neuroanatomy
• Neurophysiology
• Spinal Cord Circuitry
• +۶ مورد دیگر

Professor David I Hughes is a Professor of Neuroanatomy at the School of Psychology and Neuroscience, University of Glasgow. His research focuses on spinal dorsal horn neurocircuitry, particularly mechanisms underlying pain perception and chronic pain states. Collaborations include Dr Brett Graham (University of Newcastle, Australia) and international partners such as Prof Robert Callister (Australia) and Prof Masahiko Watanabe (Japan). His work combines anatomical and electrophysiological approaches to identify cell populations influencing touch and pain sensation. Funding sources include BBSRC, NHMRC (Australia), and NC3Rs. Notable research areas include spinal interneuron function, synaptic connectivity, and developing treatments for neuropathic pain. Key findings involve calretinin and parvalbumin-expressing neurons' roles in tactile allodynia and mechanical hyperalgesia. Teaching roles include coordinating undergraduate anatomy programs and leading advanced courses on neuroanatomy and bioimaging. He supervises BSc, MSc, and PhD students, mentoring over 10 researchers annually. Professional activities include editorial roles at Frontiers in Neural Circuits and international conference presentations. Laboratory activities are centered at the Spinal Cord Group, with lab details at davehugheslab.org . Recent grants (2023–2025) explore spinal modulation of nociceptor input and osteoarthritis pain mechanisms.

• Neurodegenerative Diseases
• Alzheimer's Research
• Neuroscience
• +۳ مورد دیگر

Prof. Martin Fuhrmann is affiliated with the University of Bonn and the Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), contributing to the Transdisciplinary Research Area (TRA) 'Life and Health'. His research focuses on cellular mechanisms in neurodegenerative diseases, particularly Alzheimer's disease (AD). He investigates how neuronal networks and synapses are disrupted under AD-like conditions, and explores microglia's influence on these processes. Using advanced techniques such as multiphoton imaging, opto/chemogenetics, electrophysiology, and behavioral assays, his work bridges molecular, cellular, and systems neurobiology. His studies aim to uncover therapeutic targets for AD and related neurodegenerative disorders. No scientific awards are explicitly listed in the provided text. His research group collaborates internationally, as evidenced by co-authored publications. No advising roles or grants are detailed here.

Shigeki Watanabeمشاهده پروفایل

دانشیار

• Cellular Neuroscience
• Molecular Neuroscience
• Synaptic Transmission
• +۴ مورد دیگر

Shigeki Watanabe is an Associate Professor of Cell Biology at the Johns Hopkins University School of Medicine. His research focuses on elucidating the cellular and molecular mechanisms underlying synaptic transmission and plasticity. He leads the Watanabe Lab, which develops innovative electron microscopy techniques, such as 'flash-and-freeze' and correlative super-resolution imaging, to study ultrastructural changes in neurons with millisecond resolution. Key research areas include synaptic vesicle recycling, synaptic proteostasis in neurodegenerative diseases, and trans-synaptic organization of neurotransmitter receptors. His work bridges static electron microscopy with dynamic cellular processes, revealing mechanisms like ultrafast endocytosis and transient docking of vesicles. The lab explores how synaptic dysfunction contributes to neurological disorders such as Parkinson’s disease, with a focus on proteins like LRRK2. Collaborations include studies on synaptotagmin function, BAR domain proteins, and glutamate receptor trafficking. Publications highlight advancements in understanding vesicle dynamics, endocytic pathways, and protein sorting at synapses. The lab’s techniques enable unprecedented insights into millisecond-scale synaptic events, advancing knowledge of neural circuit function and disease mechanisms.

Paul J. Kammermeierمشاهده پروفایل

دانشیار

• G protein-coupled receptor (GPCR) signaling
• Metabotropic glutamate receptors (mGluRs)
• Ion channel modulation
• +۳ مورد دیگر

Paul J. Kammermeier is an Associate Professor in the Department of Pharmacology and Physiology at the University of Rochester Medical Center (School of Medicine and Dentistry). His research focuses on G protein-coupled receptor (GPCR) signaling, particularly metabotropic glutamate receptors (mGluRs) and their role in ion channel modulation and synaptic plasticity. Key research areas include: Receptor dimerization mechanisms (homodimers vs. heterodimers) Homer protein scaffolding in postsynaptic signaling Calcium channel regulation by accessory subunits GPCR signal transduction specificity His lab employs electrophysiology , molecular biology , and fluorescence imaging to study both primary SCG neurons and native retinal/hippocampal systems . Collaborations include institutions like Johns Hopkins and University of Michigan. Notable honors include election as Councilor of the University of New York Pharmacology Society (2012) and co-editing the textbook Ion Channels: A Laboratory Manual (2017). His 15 most recent publications highlight trends in: GPCR heterodimerization pharmacology Calcium signaling in secretory networks Homer-Preso1 regulatory pathways Evaluating drug selectivity in glutamate receptors Quantitative imaging of protein complexes Current lab members include graduate students Tyler W. McCullock and Tahia Rahman. Former students and postdocs (e.g., Mallory Scott, Donald Beqollari) have contributed to understanding mGluR signaling and ion channel modulation.