معرفی
Professor David I Hughes is a Professor of Neuroanatomy at the School of Psychology and Neuroscience, University of Glasgow. His research focuses on spinal dorsal horn neurocircuitry, particularly mechanisms underlying pain perception and chronic pain states. Collaborations include Dr Brett Graham (University of Newcastle, Australia) and international partners such as Prof Robert Callister (Australia) and Prof Masahiko Watanabe (Japan). His work combines anatomical and electrophysiological approaches to identify cell populations influencing touch and pain sensation.
Funding sources include BBSRC, NHMRC (Australia), and NC3Rs. Notable research areas include spinal interneuron function, synaptic connectivity, and developing treatments for neuropathic pain. Key findings involve calretinin and parvalbumin-expressing neurons' roles in tactile allodynia and mechanical hyperalgesia.
Teaching roles include coordinating undergraduate anatomy programs and leading advanced courses on neuroanatomy and bioimaging. He supervises BSc, MSc, and PhD students, mentoring over 10 researchers annually. Professional activities include editorial roles at Frontiers in Neural Circuits and international conference presentations.
Laboratory activities are centered at the Spinal Cord Group, with lab details at davehugheslab.org. Recent grants (2023–2025) explore spinal modulation of nociceptor input and osteoarthritis pain mechanisms.
