Healthspan Extension Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۱۳۹ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Terje Andreas Eikemoمشاهده پروفایل

استاد

Norwegian University of Science and TechnologyNorway

Terje Andreas Eikemo is a Professor at the Department of Sociology and Political Science , Norwegian University of Science and Technology (NTNU) , and Head of the CHAIN research center . His work focuses on the intersection of social inequality , public health , and global policy , emphasizing how socioeconomic factors like education , income , and welfare systems influence mortality , chronic diseases , and mental health . He combines theories from sociology , epidemiology , and medicine to address health disparities across diverse contexts, including pandemics , climate change , and migration . 2009: Prize for Young Researchers in the Humanities 2010: SINTEF Prize for Outstanding Research 2014: NTNU Star Program Eikemo has published extensively in top journals like The Lancet and BMJ Open , with research themes spanning social determinants of health , policy interventions , and global health equity . His work includes GBD studies , European Social Survey analyses , and refugee health assessments. He serves as Editor-in-Chief of the Scandinavian Journal of Public Health and collaborates with international bodies like WHO and UNESCO .

پروفایل رسمی دانشگاه

David Walkerمشاهده پروفایل

استاد

University of California, Los AngelesUnited States

David Walker is a Professor and Vice Chair of Academic Personnel in the Department of Integrative Biology and Physiology at the University of California, Los Angeles. He leads a research lab focused on understanding the molecular and cellular basis of aging, utilizing Drosophila melanogaster to investigate mechanisms such as mitochondrial dysfunction, autophagy, and intestinal barrier integrity. His work aims to identify therapeutic targets for age-related diseases. Education: B.S., Genetics, Queen's University Belfast (1995) MRes, Molecular Biology, University of Manchester (1996) Ph.D., Genetics, University of Manchester (2000) Walker's research interests center on the biological processes driving aging, with emphasis on mitochondrial dynamics, neurodegeneration, and gut-microbiota interactions. His lab employs genetic, molecular, and physiological approaches in Drosophila to dissect how cellular deterioration impacts lifespan and healthspan, bridging insights to human aging pathologies. Key themes include the role of autophagy adaptors (e.g., p62/SQSTM1), mitochondrial fission, and intestinal homeostasis in longevity. His recent publications (2014–2024) reveal a consistent focus on brain aging, mitophagy, and gut-brain axis disruptions, with trends toward identifying midlife interventions for healthspan extension. Articles frequently integrate cellular stress responses, metabolic regulation, and neurodegeneration, highlighting Drosophila as a versatile model for translational aging research. No scientific awards, prizes, or fellowships are mentioned in the provided text. While specific grants or student advisees are not detailed, Walker's lab actively mentors researchers and contributes to collaborative projects on aging mechanisms. Future directions may involve exploring mitochondrial-immune interactions and novel longevity pathways. Walker directs a Drosophila-focused laboratory at UCLA, emphasizing genetic screens and mechanistic studies to uncover evolutionarily conserved aging pathways. The team investigates tissue-specific aging cascades, including neuronal and intestinal systems, to develop strategies for mitigating age-related decline.

پروفایل رسمی دانشگاه

Andreas Beyerمشاهده پروفایل

استاد

University of CologneGermany

Prof. Dr. Andreas Beyer holds a faculty position at the University of Cologne, affiliated with the Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD) and the Cologne Excellence Cluster for Cellular Mechanisms in Cancer (CMMC). His research focuses on systems-level analysis of aging processes in humans and model organisms, integrating genomic, proteomic, and computational approaches. Key interests include understanding how genetic variation influences protein networks, developing algorithms for big data analysis, and exploring epigenetic mechanisms related to longevity. Research projects include studying age-associated changes in transcriptional elongation, molecular networks in kidney disease, and the impact of dietary restriction on aging. His group develops tools for proteomics and systems biology, such as methods for analyzing limited proteolysis data and single-cell resolution imaging. Collaborative efforts emphasize translational research in aging-related diseases and drug discovery. Prof. Beyer’s work spans computational biology, molecular genetics, and translational medicine. Notable contributions include identifying epigenetic changes linked to longevity and developing predictive models for age-related disease progression. His lab’s projects often involve multi-omics integration and network-based analyses to uncover disease mechanisms. His research has implications for personalized medicine, cancer biology, and interventions to extend healthspan. Current efforts include optimizing drug combinations targeting aging processes and advancing proteomic technologies for clinical applications.

پروفایل رسمی دانشگاه

Shahaf Pelegمشاهده پروفایل

پژوهشگر

Research Institute for Farm Animal BiologyGermany

Dr. Shahaf Peleg is the Head of the Energy Metabolism and Epigenetics Working Group at the Research Institute for Farm Animal Biology (FBN). His research focuses on aging biology, epigenetic mechanisms, and metabolic interventions. Key areas include histone acetylation regulation, mitochondrial function, and dietary effects on longevity. He uses models like Drosophila, C. elegans, and mice (e.g., Titan mouse) to study aging pathways. Leading interdisciplinary projects on energy metabolism and epigenetic interactions. Developing optogenetic tools for mitochondrial research. Expertise in lipidomics and circadian metabolism. Recent work emphasizes dietary interventions in obesity-related aging and optogenetic rejuvenation of cellular energetics. Active in collaborative networks like ARDD Emerging Science workshops. Publications span metabolic pathway analysis, alcohol's epigenetic impacts, and longevity biomarkers. His team's Titan mouse model is a key tool for testing frailty attenuation strategies.

پروفایل رسمی دانشگاه

Sheng Liمشاهده پروفایل

دانشیار

University of Southern CaliforniaUnited States

Sheng Li is an Associate Professor of Cancer Biology at the University of Southern California's Keck School of Medicine. She co-leads the Epigenetic Regulation in Cancer Program at the Norris Comprehensive Cancer Center. Her research integrates multi-omics and computational approaches to study epigenetic heterogeneity in blood cancers, aging, and clonal hematopoiesis. Her lab focuses on single-cell spatial multi-omics, 3D epigenomics, and long-read sequencing to map epigenetic drivers of leukemogenesis. Awards include the Leukemia & Lymphoma Society Scholar Award and AACR NextGen Star recognition. She mentors PhD students and postdocs, with her team publishing extensively in high-impact journals. Her publications demonstrate a strong emphasis on computational epigenetics, cancer systems biology, and geroscience. Recent work includes developing tools for spatial transcriptomics interpretation and modeling IDH-mutant AML gene networks.

پروفایل رسمی دانشگاه

Brian Chenمشاهده پروفایل

استادیار مدعو

University of California, San DiegoUnited States

Brian Chen is an Assistant Adjunct Professor at the Herbert Wertheim School of Public Health & Human Longevity Science at the University of California San Diego (UCSD). His research focuses on biomarkers of aging, epigenetics, and epidemiological studies , with a particular interest in translating these findings into clinical applications and population health strategies. Education: PhD in Epidemiology, University of California Los Angeles (UCLA) MPH in Epidemiology/Biostatistics, University of California Berkeley Bachelor of Science in Biochemistry/Cell Biology & Psychology, UC San Diego Research Interests: Brian's work centers on understanding biological aging mechanisms through epigenetic changes, particularly DNA methylation patterns. He explores how these biomarkers correlate with age-related diseases (e.g., dementia, cardiovascular disease) and health disparities. His studies often involve large-scale epidemiological cohorts and cutting-edge genomic technologies. Publications: His recent work emphasizes validation of aging biomarkers, epigenetic clock analyses, and translational strategies for clinical implementation. Key contributions include studies on racial/ethnic health disparities linked to epigenetic aging and the role of biomarkers in predicting cardiovascular outcomes. Collaborations: Brian frequently collaborates with leading researchers like Steve Horvath (epigenetic clock pioneer), Luigi Ferrucci (aging epidemiology), and Tamara B. Horvath (neuroendocrinology). His work has been cited over 5,000 times in high-impact journals. Future Directions: Current projects include developing multi-omic aging biomarker panels and investigating interventions to modulate epigenetic aging processes. He also advocates for standardized validation frameworks for aging biomarkers in clinical settings.

پروفایل رسمی دانشگاه

Sofiya Milmanمشاهده پروفایل

استاد

Albert Einstein College of MedicineUnited States

Sofiya Milman, M.D., M.S., is a Professor in the Departments of Medicine (Endocrinology) and Genetics at Albert Einstein College of Medicine. She serves as Interim Vice Chair for Research in the Department of Medicine and Director of Human Longevity Studies at Einstein’s Institute for Aging Research. Her research focuses on genomic mechanisms underlying healthy aging, particularly in centenarian populations. Dr. Milman’s work emphasizes the role of hormonal pathways, especially the somatotropic axis involving IGF-1, in regulating longevity and age-related diseases. Her studies demonstrate that lower IGF-1 levels correlate with extended survival and cognitive health in individuals with exceptional longevity. Research interests include translational studies on longevity genes, protective endocrine parameters, and interventions to combat age-related diseases. Her work integrates genetic data with phenotypic information from longevity families to uncover molecular mechanisms driving healthspan extension. Key findings include the antagonistic pleiotropy of IGF-1, where lower IGF-1 levels may protect against cardiovascular disease and diabetes while promoting longevity. Dr. Milman’s articles span topics like IGF binding proteins’ mortality prediction, proteomic changes across lifespan, and genetic insights into extreme longevity. Grants supporting her research include NIH grants (R01 AG057909, R01 AG044829) focused on aging mechanisms. She collaborates widely, with co-authors such as Nir Barzilai and Aviv Bergman. Her lab is part of the Institute for Aging Research, dedicated to translating basic discoveries into clinical interventions for healthy aging.

پروفایل رسمی دانشگاه

Codruta Igneaمشاهده پروفایل

استادیار

McGill UniversityCanada

Codruta Ignea is an Assistant Professor in the Department of Bioengineering at McGill University , Montreal, Canada. Her research focuses on synthetic biology and metabolic engineering, specifically reconstructing biosynthetic pathways in microbial chassis for high-value compound production. Areas of Expertise : Synthetic Biology, Metabolic Engineering, Biological Membrane Engineering Contact : codruta.ignea@mcgill.ca , McConnell Engineering Building, 817 Sherbrooke Street West, Montreal, QC H3A 0C3 Her work involves designing synthetic biosystems that bio-mimic producer organism environments to enhance bioprocess performance, discovering novel enzymatic activities, and expanding natural chemical diversity for drug discovery. Key applications include pharmaceutical production and new-to-nature molecules with improved bioactivities. Recent publications highlight her contributions to yeast engineering for terpenoid biosynthesis, pathway optimization, and artificial intelligence integration in synthetic biology. Her team has developed systems for producing anti-cancer, anti-viral, and anti-inflammatory compounds through microbial platform innovation.

پروفایل رسمی دانشگاه

Sanjeeb Kumar Sahuمشاهده پروفایل

استادیار

University of Southern DenmarkDenmark

Sanjeeb Kumar Sahu is an Assistant Professor at the Department of Molecular Medicine, University of Southern Denmark (SDU), and a Fellow of Health Sciences. He specializes in molecular biology, epigenetics, and aging research, focusing on cellular aging, senescence regulation, and age-related diseases. He holds a Ph.D. from Johannes Gutenberg University (JGU) in Mainz, Germany. His research explores strategies to combat aging through targeted partial reprogramming and inflammation modulation. Notable contributions include studies on muscle regeneration, epigenetic crosstalk in metastasis, and lifespan extension in mouse models. He is committed to interdisciplinary collaboration and mentoring early-career scientists. Publications span prestigious journals like Science Translational Medicine , Nature Cell Biology , and Nature Aging . His work emphasizes translational applications of aging mechanisms, aiming to improve healthspan through innovative biological approaches.

پروفایل رسمی دانشگاه

Sabrina Büttnerمشاهده پروفایل

استاد

University of MünsterGermany

Prof. Sabrina Büttner leads the Cell Biology group at the Institute of Integrative Cell Biology and Physiology, University of Münster. Her research focuses on intracellular communication during cellular aging, stress responses, and metabolic adaptation, utilizing yeast and Drosophila models. She investigates organelle connectivity via membrane contact sites and their role in proteostasis, neurodegeneration, and longevity. Her work integrates molecular biology, genetics, and imaging to explore: Organelle communication networks Proteostasis collapse in aging Autophagy and lipid metabolism Neurodegenerative disease mechanisms Recent publications emphasize membrane contact sites, stress-induced nuclear/vacuole dynamics, and autophagy regulation. Trends include organelle interfaces in proteostasis, mitochondrial quality control, and translational applications in longevity biotechnology. She mentors PhD students including Irene Álvarez-Guerra, Emma Block, Patricia Grabher, and Simon Prokisch. Her lab collaborates with CRC projects (e.g., CRC 1009, 1348, 1459, 944) and graduate programs (CiM-IMPRS, IRTG, SP BioSciences).

پروفایل رسمی دانشگاه

Steve Jacksonمشاهده پروفایل

استاد

University of CambridgeUnited Kingdom

Steve Jackson is a Professor in the Department of Biochemistry at the University of Cambridge, where he leads the Jackson Group focused on DNA damage response research. His work is affiliated with the Cancer Research UK Cambridge Institute, reflecting the translational nature of his investigations into genome stability mechanisms. Department of Biochemistry, University of Cambridge Cancer Research UK Cambridge Institute Leader of the Jackson Research Group Professor Jackson's research centers on understanding how cells detect and repair DNA damage, particularly double-strand breaks. His work examines the structure and function of DNA damage response (DDR) proteins, how chromatin structure and cell cycle status affect DDR events, and the application of gene editing and whole genome sequencing to identify potential therapeutic targets for cancer treatment. His research has significant implications for understanding cancer development, neurodegenerative diseases, and premature aging. Analysis of Jackson's publication record reveals consistent focus on DNA repair mechanisms, with recent work (2018-2019) emphasizing chromatin dynamics in DNA damage response, BRCA1-related repair pathways, and connections between DNA damage and aging. His research bridges fundamental molecular biology with clinical applications, particularly in cancer therapeutics. Professor Jackson actively mentors the next generation of scientists, with his group accepting interns, undergraduate students, postgraduate students, and postdoctoral researchers. While specific grant details aren't provided in the text, his affiliation with Cancer Research UK suggests significant research funding supporting his work. The Jackson Group maintains a dedicated research facility focused on genome stability research, utilizing advanced techniques including gene editing and whole genome sequencing to investigate DNA damage response mechanisms and their relationship to human disease.

پروفایل رسمی دانشگاه

Jessica Tylerمشاهده پروفایل

استاد

Cornell UniversityUnited States

Jessica Tyler is a Professor in the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine, where she also holds affiliations with the Graduate School of Medical Sciences. She leads the Laboratory of Epigenetics and Genomic Integrity, conducting cutting-edge research on chromatin dynamics, DNA repair, and aging using budding yeast and human cell models. PhD, Molecular Virology, University of Glasgow (1994) Bachelor’s Degree, Biochemistry, University of Sheffield (1990) Postdoctoral Training, UCSD under Jim Kadonaga Former Faculty: University of Colorado School of Medicine, MD Anderson Cancer Center Dr. Tyler’s research focuses on epigenetics, genomic integrity, and longevity , particularly how chromatin structure regulates DNA repair, gene expression, and aging. She investigates conserved mechanisms using yeast genetics, biochemistry, and genome-wide analyses. Her lab discovered that histone depletion occurs during aging and that overexpression of histones extends lifespan. They also pioneered studies on the tardigrade Dsup protein, showing it protects chromatin and enhances longevity in yeast. The recent publications reflect a strong focus on DNA double-strand break repair, chromatin assembly, histone chaperones (e.g., CAF-1, ASF1), and aging . Work spans from mechanistic biochemistry to systems-level genomics, often linking chromatin dynamics to disease processes like cancer and neurodegeneration. Technologies include CRISPR, microfluidics, proximity ligation, and high-resolution sequencing. Fellow of the American Association for the Advancement of Science (AAAS), 2017 National Academy of Sciences Kavli Fellow, 2011 University of Glasgow Tenovus Medal, 2010 AACR Woman in Cancer Research Charlotte Friend Memorial Award, 2009 Dean’s Mentor of the Year, 2009 Faculty Educator of the Month, 2015 Dr. Tyler has mentored numerous graduate students and postdoctoral fellows, many of whom now hold faculty or industry positions. She is Principal Investigator on multiple NIH-funded grants exploring chromatin’s role in DNA repair and aging. Her lab actively welcomes rotation and graduate students. The Tyler Lab is located at Weill Cornell Medicine, 1300 York Avenue, New York, NY.

پروفایل رسمی دانشگاه

Zhengdong Zhangمشاهده پروفایل

استاد

Albert Einstein College of MedicineUnited States

Zhengdong Zhang is a Professor in the Department of Genetics at Albert Einstein College of Medicine. His research focuses on the genetics of aging, Alzheimer's disease, and complex human diseases, combining computational methods with clinical data to uncover genetic mechanisms. His lab develops novel algorithms for genetic analysis, including post-GWAS gene prioritization, Bayesian statistical methods for genomic data, and systems biology approaches. Education details are not explicitly listed, but his professional background includes significant contributions to computational genetics and aging research. Key research areas include method development for genetic analysis, aging-related genetic networks, and disease genetics of Alzheimer's and schizophrenia. His lab has pioneered studies on long-lived species' genomic features, such as naked mole rats and beavers, to understand longevity and disease resistance. Research highlights include identifying rare coding variants linked to schizophrenia risk in 22q11.2 deletion syndrome patients, developing frameworks for Alzheimer's immune pathway analysis, and exploring DNA repair mechanisms in long-lived species. His work emphasizes interdisciplinary approaches integrating data science with clinical insights. Zhengdong Zhang's lab is located in the Michael F. Price Center at Einstein College of Medicine, focusing on translational research to bridge genetic discoveries with clinical applications.

پروفایل رسمی دانشگاه

Lee S. Berkمشاهده پروفایل

پژوهشگر

Loma Linda UniversityUnited States

Dr. Lee S. Berk is the Associate Dean of Research at the School of Allied Health Professions and an Associate Research Professor in the Department of Pathology and Human Anatomy at the School of Medicine , Loma Linda University . His research spans psychoneuroimmunology , focusing on the physiological effects of mirthful laughter , humor , and neuroendocrine responses on stress, immune function, and brain health. Dr. Berk has served on numerous committees, including the Loma Linda University Health Research Oversight Committee and Board of Directors of the American College of Lifestyle Medicine . He has been an Editorial Board Member for the Journal of Physical Therapy and Rehabilitation and Advances in Mind-Body Medicine . His advisory roles include mentoring doctoral candidates Olivia Moses and Micheline Vargas . Over his career, Dr. Berk has been extensively featured in media outlets (e.g., CNN , NPR , Newsweek ) and has contributed to over 150 peer-reviewed publications. His work explores EEG gamma wave modulation , anti-oxidant effects on autism , and exercise interventions for inflammation and metabolic health . Current projects include studies on brain health , type 2 diabetes , and religious cognitive-behavioral therapy outcomes.

پروفایل رسمی دانشگاه

Joshua C. Drakeمشاهده پروفایل

استادیار

Virginia Polytechnic Institute and State UniversityUnited States

Joshua C. Drake, PhD, is an Assistant Professor in the Department of Human Nutrition, Foods, and Exercise at Virginia Polytechnic Institute and State University. His research focuses on molecular mechanisms of cellular energetics, particularly how these processes change with aging and contribute to age-related diseases like diabetes and Alzheimer’s. He holds a PhD in Human Bioenergetics from Colorado State University (2014) and prior degrees from West Virginia University. His work has been funded by notable grants including NIH/NIA awards and the SJ Ritchey Research Grant. Key contributions include studies on AMPK signaling, mitochondrial quality control, and the interplay between skeletal muscle and brain health in aging. Dr. Drake’s research lab investigates energetic sensing pathways in skeletal muscle, emphasizing how metabolic flexibility declines with age. His team uses mouse models to explore interventions like exercise and caloric restriction, aiming to uncover therapeutic targets for age-related metabolic disorders. Recent findings highlight Ulk1 phosphorylation’s role in metabolic adaptations and the protective effects of exercise in neurodegenerative diseases. Awards: NIH/NIA R01 (2023), SJ Ritchey Grant (2022), NIH/NIA R00 (2020) Education: PhD, Human Bioenergetics, Colorado State University (2014) M.S., Exercise Physiology, West Virginia University (2010) B.S., Exercise Physiology, West Virginia University (2007) Dr. Drake mentors students in experimental and translational research, including studies on Alzheimer’s disease mechanisms and mitochondrial dysfunction. His work bridges basic science and clinical applications, with a focus on extending healthspan through metabolic interventions.

پروفایل رسمی دانشگاه