Hauke Smidt is a Personal Professor at Wageningen University & Research, affiliated with the Molecular Ecology group within the Faculty of Veterinary Medicine and Animal Sciences. His research focuses on microbial ecology, particularly gut microbiota dynamics, antibiotic resistance, environmental microbiology, and the One Health framework. Smidt has supervised over 50 PhD students and contributed to 519 publications, including studies on microbiome resilience, fermented food impacts, and bioremediation strategies. Education and affiliations include leadership roles in projects addressing antimicrobial resistance, pig health, and drinking water microbiology. His work spans collaborations across Europe and Asia, with notable contributions to understanding microbial community responses to environmental stressors and dietary interventions. Smidt is actively involved in public outreach, as seen in media contributions discussing microbiome research and health benefits. Key projects include aquifer treatment for drinking water, microbiome simulation models, and combating plant pathogens. His awards and recognition are not explicitly listed, but his extensive publication record and project leadership highlight significant academic impact.
David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.
David John Procter is a Professor of Organic Chemistry and Head of the Department of Chemistry at the University of Manchester. His career includes academic roles at the University of Glasgow (Lecturer, Senior Lecturer) and a Readership at the University of Manchester, where he became a Professor in 2008. His research focuses on developing new synthetic methods, catalysis, and materials chemistry, with applications in drug discovery, biocatalysis, and organic electronics. Education: BSc Chemistry (University of Leeds, 1992), PhD (1995, supervised by Prof. Christopher Rayner). Postdoctoral work: Florida State University (Prof. Robert Holton, Taxol analog synthesis). Research interests include samarium diiodide-mediated reactions, metal-free coupling processes, and sustainable synthesis methods. He leads projects funded by EPSRC, Industry (30 grants), and international collaborations. Awards include the EPSRC Established Career Fellowship (2015–2020), Bader Prize (2014), and Young Heterocyclic Chemist Award (2015). Key contributions: Total synthesis of natural products (e.g., pleuromutilin), development of copper-catalyzed multicomponent couplings, and innovative methods for organic materials. His work aligns with UN Sustainable Development Goals related to affordable and clean energy and responsible consumption. Collaborations span academic and industrial partnerships in chemistry, physics, and biology. He supervises 60+ students and contributes to the Organic Materials Innovation Centre (OMIC). His group’s research is detailed at proctergroupresearch.com .
Denis Fougerouse is a Senior Lecturer at Curtin University’s School of Earth and Planetary Sciences (EPS), specializing in structural and economic geology with a focus on nanogeoscience and advanced characterization techniques. He leads research using atom probe tomography (APT) to study mineral interfaces, fluid dynamics, and critical metal distribution. His work spans asteroid mineralogy (e.g., Ryugu samples), ore genesis, and nuclear geology (e.g., Chernobyl zircon re-equilibration). Fougerouse is a key member of Curtin’s Geoscience Atom Probe Facility, advancing applications of APT in geosciences. Research interests include gold remobilization mechanisms, sulfide chemistry, and shock metamorphism. He has contributed to landmark studies on pyrite microtextures, xenotime geochronology, and nanoparticle transport in gold deposits. Fougerouse’s awards include the 2024 Mineralogical Society of America Award for pioneering nanoscale mineral analysis. His interdisciplinary collaborations span planetary science, environmental geochemistry, and materials science, reflecting his role at the forefront of geoscience innovation.
Prof. Dr. Mathias Christmann is a faculty member at the Institute of Chemistry and Biochemistry, Freie Universität Berlin , leading the research group in Organic Chemistry . His work focuses on strategic and methodological challenges in synthetic chemistry, particularly in total synthesis, organocatalysis, and renewable resource transformations. Position: Professor Contact: mathias.christmann@fu-berlin.de Location: Takustr. 3, Room 24.16, 14195 Berlin Research Interests include: Natural product-inspired small molecule synthesis for biological pathway modulation Minimizing C-C bond formations through selective functionalization of terpene building blocks Organocatalytic and metal-catalyzed reactions in multistep sequences Flow chemistry applications for scalable and sustainable synthesis Biological evaluation of TRPC channel agonists/antagonists for cancer therapy Publication Trends highlight expertise in total synthesis of complex terpenoids, organocatalysis for stereocontrolled reactions, flow chemistry for late-stage transformations, and TRPC4/5 channel modulation in renal cancer studies. His group pioneers asymmetric desymmetrization , photo-oxidation protocols , and electrosynthesis methods with minimal reagent waste. Advisees include PhD candidates Jan-Hendrik Dickoff , Mayar Elbendary , Nadine Kreidt , Tobias Olbrisch , Kamar Shakeri , and Zhen Wang , focusing on terpene-based drug discovery and catalytic reaction design.
Michael Groll serves as Professor and Chair of Biochemistry at the Technical University of Munich (TUM), where he leads structural biology and enzymology research with a focus on proteasome mechanisms and inhibitor development. His laboratory, located at the Ernst-Otto-Fischer-Str. 8 campus in Garching, maintains active collaborations in drug discovery for cancer and infectious diseases. His primary research domains include proteasome inhibition, enzyme catalysis, and natural product biosynthesis, employing X-ray crystallography, biochemical assays, and bioengineering to dissect molecular mechanisms. Recent work emphasizes AI-guided enzyme optimization, bacterial stress response targeting, and structural characterization of halogenation enzymes, reflecting interdisciplinary approaches bridging chemistry and biology. Analysis of his 2023-2025 publications reveals consistent innovation in proteasome-targeted therapeutics, with 15 high-impact papers featuring structural insights into enzyme-inhibitor complexes and biosynthetic pathways. Key trends include engineering megasynthetases for immunoproteasome inhibitors, optical control of protein degradation, and elucidating metal-dependent mechanisms in antibiotic biosynthesis. No scientific awards were documented in the provided source material. While specific grant details and student mentorship records were not disclosed, his extensive publication record indicates leadership in collaborative research projects involving structural biology and chemical biology methodologies. The Chair of Biochemistry under Prof. Groll operates as a hub for structural enzymology, housing facilities for protein crystallography, enzyme kinetics, and natural product characterization. His team actively contributes to TUM's research ecosystem through partnerships with pharmaceutical groups and international structural biology consortia.
Amy E. Fraley is an Assistant Professor at ETH Zürich, Department of Chemistry and Applied Biosciences, and leads the Medicinal Chemistry Research Group. Her cross-disciplinary work bridges natural products biosynthesis, pharmaceutical sciences, and environmental sustainability through enzymatic chemistry and biotechnology. BSc in Chemistry, Millersville University of Pennsylvania (2014) PhD in Medicinal Chemistry, University of Michigan College of Pharmacy (2019) Postdoctoral work at ETH Zürich Institute of Microbiology under Prof. Jörn Piel Her research focuses on harnessing biosynthetic enzymes (e.g., halogenases, monooxygenases, Diels-Alderases) to create sustainable bioactive metabolites. She explores natural product biosynthesis in fungi and marine bacteria, targeting disease mechanisms and green chemistry applications. Recent work includes metagenomic studies of Lake Chilika microbial mats and polyketide synthase engineering. Notable scientific awards include the 2024 JSP Fellow at Bürgenstock Conference, 2018 Rackham Predoctoral Fellowship, and multiple University of Michigan honors. Her group secured funding from the ETH4D Doctoral Mentorship Grant and Messerli Foundation . Collaborations span structural biology, synthetic chemistry, and microbiology, with key contributions to flavoenzyme characterization and bioactive compound libraries . The lab emphasizes interdisciplinary training and innovation in biocatalytic tools for organic synthesis.
Megan L. Matthews is an Assistant Professor in the Department of Chemistry at the University of Pennsylvania, School of Arts & Sciences, where she leads an active research group focused on chemical biology and enzymology. Her lab develops innovative chemical proteomics technologies to uncover novel enzyme cofactors and regulatory post-translational modifications, particularly those involving reactive electrophiles, which cannot be predicted from genomic sequences. B.S. in Chemistry, Miami University (2005) Ph.D. in Chemistry, The Pennsylvania State University (2011) Postdoctoral Fellow, The Scripps Research Institute (2012–2017) Her research centers on the concept of the 'electrophilome'—a largely unexplored half of the reactive proteome. By designing 'reverse-polarity' chemical probes, her group enables the discovery of functionally significant electrophilic modifications in proteins, especially those involved in cancer and Alzheimer’s disease. These discoveries open new avenues for therapeutic intervention through covalent targeting. The recent publications demonstrate a consistent focus on enzyme mechanisms, cofactor discovery, and chemical probe development. Her work spans from fundamental enzymology (e.g., halogenases, ribonucleotide reductases) to applied chemical biology (e.g., hydrazine probes, chemoproteomic profiling). The keywords across her publications highlight emerging themes in metalloenzymes, radical chemistry, and covalent proteome mapping. Her scientific contributions have been recognized through prestigious fellowships, including the Merck Helen Hay Whitney Postdoctoral Fellowship. She has published in top-tier journals such as Nature , Nature Chemical Biology , and Journal of the American Chemical Society . Dr. Matthews advises graduate students and postdoctoral researchers in her lab, fostering a collaborative and inclusive environment. Her lab emphasizes the importance of diverse perspectives in scientific discovery. She has secured research funding to support projects in probe development, target characterization, and disease mechanism studies, particularly in neurodegenerative diseases and cancer. The Matthews Lab is actively engaged in advancing reverse-polarity activity-based protein profiling (RP-ABPP) for in vivo applications and inhibitor screening. The group collaborates with experts in structural biology, spectroscopy, and disease modeling to translate basic discoveries into therapeutic insights.
Andy Ball is a Distinguished Professor in the School of Science at RMIT University, specializing in environmental microbiology and biotechnology. He leads the ARC Training Centre for the Transformation of Australia’s Biosolids Resource and has held key roles at institutions including the University of Essex and Flinders University. His research focuses on bioremediation, organic waste treatment, and environmental pollution solutions, with over 300 peer-reviewed publications and significant industry collaboration. Andy's academic career spans 30 years, with roles such as Director of the Centre for Environment and Society at Essex and Director of Flinders Bioremediation. He has attracted >$22M in research grants, particularly in applied environmental microbiology. His awards include the Royal Society of Victoria Medal (2021) and RMIT Research Excellence Award (2018). Research interests emphasize sustainable remediation of contaminated environments, leveraging microbial ecology and biotechnology. His teaching spans environmental science and biotechnology programs at RMIT. Andy advises on projects addressing bioremediation, bioenergy, and pathogen survival, with active collaborations with industries like Shell and Melbourne Water.
Dr. Gregory Perry is a Lecturer in Organic Chemistry at the University of Southampton (UK), leading an independent research group focused on discovering novel reactivity for molecular synthesis and transformation. His career includes postdoctoral research at Nagoya University and Kyoto University, and previous fixed-term lecturer roles at the University of Manchester. Research Interests: Organic synthesis with a focus on catalysis Carbon and nitrogen isotope labelling techniques Metal-halogen exchange reactions CO2 utilization in synthetic chemistry Transition-metal-free cross-coupling methods Notable Contributions: His recent work explores sulfonium salts for aromatic coupling, sustainable biaryl synthesis, and stomatal-regulating molecule development. Articles span topics like organolithium reagents, bimetallic catalysis, and molecular semiconductor synthesis. Academic Background: MChem in Chemistry (2012), University of Liverpool PhD in Organic Chemistry (2016), University of Manchester Current Collaborations: Affiliated with the ChemLife Network, Institute for Life Sciences, and groups led by Professors Hideki Yorimitsu and David J. Procter.
David Chester Upham is an Assistant Professor in the Department of Chemical & Biological Engineering within the Faculty of Applied Science at the University of British Columbia (UBC). He leads the Upham Lab, which focuses on developing catalysts and processes for sustainable energy production, greenhouse gas mitigation, and CO 2 -free chemical conversion. Dr. Upham received his education from prestigious institutions: Postdoctoral Scholar, Stanford University (2019) Ph.D., University of California Santa Barbara (2017) B.Eng., McGill University (2010) Dr. Upham's research focuses on heterogeneous catalysis for sustainable energy applications. His work centers on developing catalysts and processes that enable CO 2 -free production of chemicals, power, and materials. He specializes in liquid heterogeneous catalysts , particularly molten metal alloys, for methane conversion, CO 2 utilization, and hydrogen production. His lab employs advanced techniques including operando IR spectroscopy, pulsed and transient analysis of reaction mechanisms, isotopic labeling studies, and in-situ X-ray absorption spectroscopy. A key aspect of his research is understanding how liquid heterogeneous catalysts behave under reaction conditions, with applications in methane pyrolysis, dry reforming, and carbon fiber synthesis. Analysis of Dr. Upham's recent publications reveals a strong focus on CO 2 mitigation and clean energy production . His work spans multiple domains including methane conversion technologies, CO 2 -to-fuels processes, and carbon-negative fuel production. A significant portion of his research investigates molten metal catalysts for methane pyrolysis and dry reforming, with applications in hydrogen production and carbon capture. His publications demonstrate an interdisciplinary approach combining chemical engineering, materials science, and environmental engineering to address climate change challenges through innovative catalytic processes. Dr. Upham actively mentors a diverse group of graduate students and researchers. His lab currently includes multiple PhD and MASc students working on various aspects of catalysis and clean energy: PhD Students: Mark Tabbara, Genpei Cai, Natascha Miederhoff MASc Students: Michael Byun, Sawyer d'Entremont, Rami Jubeili, Wyatt Schnare Postdoctoral researcher: Sonit Balyan Multiple undergraduate and visiting students from institutions worldwide The Upham Lab operates within UBC's Catalysis Labs, utilizing advanced experimental techniques to study reaction mechanisms and develop new catalysts. The lab's research has significant implications for decarbonizing the energy and chemical sectors, with potential applications in hydrogen production, carbon fiber manufacturing, and CO 2 -to-fuels technologies.
Dr. William Unsworth is a Senior Lecturer in the Department of Chemistry at the University of York. He holds a Leverhulme Trust Early Career Fellowship and the inaugural Eleanor Dodson Fellowship. His research focuses on developing new methods for synthesizing functionalized macrocycles, spirocycles, heterocycles, and natural products, with key interests in ring expansion strategies (e.g., SuRE methodology), photochemistry, catalysis, and spirocyclization reactions. Education: Bachelor's and PhD in Chemistry from the University of Oxford (PhD under Prof. Jeremy Robertson, 2010) Postdoctoral Research Associate with Prof. Richard J.K. Taylor at the University of York (2010–2013) Research Interests: Macrocycle synthesis, medium-sized rings, cascade reactions, photochemical radical processes, and catalyst-driven scaffold diversity. His group’s work emphasizes practical applications in medicinal chemistry and drug discovery. Awards: Thieme Chemistry Journals Award (2020) RSC Hickinbottom Award (2018) European Lead Factory Chemical Library Creativity Award (2017) RSC/BMOS Young Investigator Award (2015) Grants and Projects: Leads initiatives like the ‘Macrocycles for Drug Discovery (MC4DD)’ project funded by the European Commission, and collaborates on projects involving biocatalysis and natural product synthesis. Labs/Teams: The Unsworth Research Group at the University of York includes collaborators like Prof. Richard Taylor and Prof. Gideon Grogan, focusing on interdisciplinary synthetic chemistry and sustainable methods.
Geoffrey Tranmer is a Tenured Associate Professor in the College of Pharmacy at the University of Manitoba. His research integrates medicinal chemistry, drug discovery, and synthetic organic methodologies, with a focus on flow chemistry and targeted cancer therapies. NSERC Post-Doctoral Fellow, University of Cambridge Post-Doctoral Fellow, Princeton University PhD in Organic Chemistry, University of Guelph BSc (Hons) in Chemistry, Brock University His research explores: Development of flow chemistry techniques to enhance synthetic organic methods Lead generation and optimization in drug discovery Bioconjugation strategies for chemical biology applications Targeted cancer therapies leveraging hypoxia-activated prodrugs Recent publications highlight his work in neurodegenerative disease drug design, biomarker discovery, and sustainable synthesis technologies. Scientific Awards CIHR Project Grant (2024-2029) NSERC Discovery Grant (2023-2028) CIHR Bridge Grant (2022) NSERC Alliance Grant (2020) NSERC Engage Grant (2017) Research Manitoba New Investigator Operating Grant (2017) Dr. Tranmer's industrial experience at Merck Frosst and academic leadership at Manitoba position him uniquely to bridge chemistry-biology-industry collaborations. His lab actively trains graduate students in cutting-edge synthesis platforms.
Professor Gideon James Grogan is a distinguished academic at the University of York, holding a position in the Department of Chemistry within the Faculty of Sciences. With expertise spanning structural and applied enzymology, he leads research at the intersection of chemistry and biology, developing novel biocatalysts for sustainable chemical synthesis and pharmaceutical applications. Professor Grogan's research focuses on the identification, characterization, and application of enzymes with biotechnological potential. His work encompasses: Oxygenases including P450s, flavoprotein monooxygenases, and peroxygenases Reductases such as ketoreductases (KREDs), imine reductases (IREDs), and reductive aminases (RedAms) Lyases catalyzing asymmetric hydration of alkenes Ligases for amide bond formation His multidisciplinary approach integrates synthetic chemistry, microbiology, molecular biology, and X-ray crystallography to engineer enzymes using in vitro evolution techniques. Recent research has yielded significant advances in biocatalytic pathways for chiral pharmaceutical precursors and renewable material processing. Professor Grogan's publication record demonstrates consistent innovation in biocatalysis, with recent work focusing on peroxygenase applications, reductive amination technologies, and enzyme engineering for improved catalytic properties. His research shows strong trends in developing sustainable enzymatic routes for pharmaceutical synthesis, with particular emphasis on stereoselective transformations and cascade reactions. Professor Grogan has received significant research funding through major grants from: BBSRC (Biotechnology and Biological Sciences Research Council) EPSRC (Engineering and Physical Sciences Research Council) He actively supervises PhD students and collaborates extensively both within the University of York and internationally. His work bridges the Departments of Chemistry and the York Structural Biology Laboratory (YSBL), leveraging state-of-the-art facilities for organic synthesis, protein expression, and structural analysis. Professor Grogan maintains strong industry connections, translating fundamental research into practical applications for pharmaceutical and chemical manufacturing. His current projects include sustainable production of menthol enantiomers, development of native amine dehydrogenases for chiral amine synthesis, and discovery of securinine alkaloid biosynthesis pathways.
Vinayak Agarwal is an Assistant Professor at the Georgia Institute of Technology with joint appointments in the School of Chemistry and Biochemistry and School of Biological Sciences within the College of Sciences. His research investigates natural products—small organic molecules produced by living organisms that form the basis of most clinical antibiotics and drugs, while also addressing environmental toxins and pollutants. Dr. Agarwal's work integrates (meta)genomics, biochemistry, structural and mechanistic enzymology, mass spectrometry, and analytical chemistry to answer fundamental questions about natural product biosynthesis. His lab specializes in marine systems, particularly marine sponges and associated microbiomes, with a focus on enzyme discovery, pathway elucidation, and biosynthetic engineering. Key research themes include halogenation enzymes, polyketide synthases, and peptide natural products, driven by the dual goals of drug discovery and environmental protection. Analysis of recent publications reveals a strong emphasis on marine natural product discovery, enzyme characterization, and biosynthetic pathway engineering. His team frequently combines genomic mining with chemical and biochemical validation, with growing attention to environmental implications of natural product chemistry and applications in antibiotic development. Dr. Agarwal has received significant recognition for his research and teaching: ASP Matt Suffness Young Investigator Award (2024) Camille Dreyfus Teacher Scholar award (2023) NSF CAREER award (2023) Cottrell Scholar Award (2021) Blanchard Assistant Professorship (2020) Harold Nation young faculty award (2019) He has mentored multiple PhD students to completion (Ipsita, Dongqi, Luna) and currently advises Vidya and Grace. His lab secures major funding from the NSF (CAREER), NIH (NIGMS MIRA), and Research Corporation for Science Advancement (Cottrell Scholar), alongside the Camille Dreyfus award and Petit Institute seed grants for collaborative marine research. The Agarwal Lab operates from the Petit Biotechnology Building at Georgia Tech and maintains a dynamic team structure with postdocs (Weimao Zhong, Nirmal Saha), graduate students (Sophia, Vidya, Beeta, Grace), and undergraduates. The lab emphasizes interdisciplinary collaboration, particularly with marine biology groups at Georgia Tech and external institutions for sample collection and structural analysis.
