Mathias Christmann

Prof. Dr. Mathias Christmann is a faculty member at the Institute of Chemistry and Biochemistry, Freie Universität Berlin, leading the research group in Organic Chemistry. His work focuses on strategic and methodological challenges in synthetic chemistry, particularly in total synthesis, organocatalysis, and renewable resource transformations.

• Position: Professor
• Contact: mathias.christmann@fu-berlin.de
• Location: Takustr. 3, Room 24.16, 14195 Berlin

Research Interests include:

• Natural product-inspired small molecule synthesis for biological pathway modulation
• Minimizing C-C bond formations through selective functionalization of terpene building blocks
• Organocatalytic and metal-catalyzed reactions in multistep sequences
• Flow chemistry applications for scalable and sustainable synthesis
• Biological evaluation of TRPC channel agonists/antagonists for cancer therapy

Publication Trends highlight expertise in total synthesis of complex terpenoids, organocatalysis for stereocontrolled reactions, flow chemistry for late-stage transformations, and TRPC4/5 channel modulation in renal cancer studies. His group pioneers asymmetric desymmetrization, photo-oxidation protocols, and electrosynthesis methods with minimal reagent waste.

Advisees include PhD candidates Jan-Hendrik Dickoff, Mayar Elbendary, Nadine Kreidt, Tobias Olbrisch, Kamar Shakeri, and Zhen Wang, focusing on terpene-based drug discovery and catalytic reaction design.