جست‌وجوی استاد و پژوهشگر

• Statistical Bioinformatics
• Precision Medicine
• Genomics
• +۵ مورد دیگر

Andy Tran is an Education-Focused Lecturer in the School of Mathematics and Statistics at The University of Sydney, part of the Faculty of Science. He holds a PhD in statistical bioinformatics from the University of Sydney. His research interests span precision medicine, computational biology, genomics, and the development of bioinformatics tools for analyzing single-cell multi-omic data and gene regulatory networks. His work integrates systems biology approaches to address challenges in cell reprogramming, allograft dysfunction, and viral pathogenesis. Tran’s publications reflect a focus on precision medicine pathways, transcriptomic analysis, and scalable methodologies for understanding cell-cell communication in diseases like COVID-19. His educational role emphasizes innovative teaching strategies using tools like SCDNEY for data storytelling. While no awards are explicitly mentioned, his contributions to computational frameworks such as scREMOTE highlight his technical expertise. He actively supervises research projects and contributes to interdisciplinary collaborations within the Faculty of Science. His research spans from foundational studies in systems biology to applied computational models, with a commitment to advancing both academic and clinical applications of bioinformatics. Current work includes optimizing multi-platform precision medicine strategies and leveraging single-cell data to decode complex biological systems.

• Neuroscience
• Pain mechanisms
• Itch perception
• +۴ مورد دیگر

Dr Junichi Hachisuka is a Senior Lecturer in Neuroscience at the University of Glasgow's School of Psychology & Neuroscience. His research focuses on spinal cord circuits underlying pain and itch perception, with particular emphasis on neuronal signaling pathways and circuit mechanisms. He has contributed to understanding how somatostatin-expressing neurons modulate pain pathways and how spinal dynorphin neurons mediate opioid-induced itch. His work combines electrophysiological techniques, optogenetics, and ex vivo spinal cord models to study neuronal plasticity and circuit dynamics. Key research areas include: Functional organization of spinoparabrachial pathways Neuromodulatory mechanisms in chronic itch Role of spinal interneurons in pain sensitization Development of in vivo/ex vivo spinal cord models Current grants include investigations into lamina I projection neurons' roles in pain mechanisms (Medical Research Council, 2022–2024) and neurotropic virus functional biology (Biotechnology and Biological Sciences Research Council, 2023–2025). Dr Hachisuka collaborates widely, including with teams at the University of Glasgow and international institutions. His lab's work bridges basic neuroscience with translational research in dermatological and chronic pain conditions.

Lisa Smithمشاهده پروفایل

مدرس ارشد

• Plant Reproduction
• Receptor Kinases
• Epigenetics
• +۵ مورد دیگر

Dr Lisa Smith is a Senior Lecturer at the School of Biosciences, University of Sheffield (2024–present), following roles as Lecturer (2013–2023) and Postdoctoral Fellow at the Max Planck Institute (2007–2013). She holds a PhD from The Sainsbury Laboratory and a BSc from The University of Queensland. Her research focuses on plant reproduction, receptor kinases, and epigenetic regulation. Key projects include studying malectin domain proteins in fertilization and cell division, funded by BBSRC and Leverhulme Trust grants. She collaborates with groups at the University of Sheffield and internationally. Teaching includes modules on plant form/function and future plant biotechnology. The Smith Lab emphasizes inclusivity and investigates plant adaptation through epigenetics and transposable elements. Research Interests: Plant reproduction signaling, receptor kinase function (e.g., HERK1/ANJ proteins), epigenetic mechanisms in stress adaptation, and transposable element dynamics. Recent work highlights roles in pollen tube reception, cell division motor proteins, and transgenerational epigenetic memory. Grants & Collaboration: BBSRC-responsive grant for receptor kinase studies, Leverhulme Trust grant for kinesin research. Collaborates with Andrew Fleming, Sam Amsbury, and external partners on epigenetics and plant development. Lab Activities: Hosts postdocs (Alice Baillie, Louis Tirot) and technicians (Peijun Zhang). Offers PhD opportunities via Yorkshire Biosciences DTP, focusing on plant reproduction, epigenetics, and cell division.

• Cardiovascular Biology
• Regenerative Medicine
• Stem Cell Research
• +۳ مورد دیگر

Prof. Bernd Fleischmann is the Head of the Institute of Physiology I at the Faculty of Medicine, University of Bonn. His research focuses on cardiovascular physiology and regenerative medicine, particularly addressing mechanisms of cardiac dysfunction and regeneration post-myocardial infarction. His group combines molecular biology, stem cell models, and in vivo experimentation to explore approaches for mending damaged hearts through cell transplantation and cellular reprogramming. Research interests include the mechanistic study of cardiovascular diseases using in vitro/in vivo models (e.g., hiPS cells), cardiac cell cycle regulation, and stem cell-derived cardiomyocyte therapies. Recent work highlights advancements in pulmonary hypertension treatment via Gq inhibition and insights into telomere dynamics during cardiomyocyte maturation. Key collaborations involve the Life & Brain Center and Bonn Center of Neurosciences. His lab employs transgenic mouse models and embryonic stem cell systems to investigate cardiac regeneration strategies. Students under his guidance include Alexander Brückner, Esther Carls, and others. Affiliations: Institute of Physiology I, Bonn Technology Campus Labs/Teams: Fleischmann Group (Physiology I)

Patrick J. Murphyمشاهده پروفایل

استادیار

• Epigenetics
• Gene Regulation
• Developmental Biology
• +۴ مورد دیگر

Patrick J. Murphy is an Assistant Professor in the Department of Biology at the University of Rochester’s School of Arts & Sciences. His research focuses on mechanisms governing gene expression during development and disease, particularly using zebrafish and mammalian models to study epigenetic regulation of cell identity transitions. He earned a PhD and holds expertise in chromatin dynamics, developmental genomics, and bioinformatics. Research Interests include: Regulation of vertebrate gene transcription in vivo Epigenetic and chromatin dynamics Zebrafish genetics & genomics Developmental cell state transitions Advanced genomic technologies Publications span topics like histone chaperones in neurons, pluripotency reacquisition, and paternal epigenetic effects of smoking. His work combines classic developmental biology with modern genomics and bioinformatics tools. No scientific awards are explicitly listed, though his high-impact publications reflect significant contributions. Advising no listed students, but collaborates on projects involving chromatin and epigenetic reprogramming. Active in the Murphy Lab, which leverages zebrafish systems for mechanistic insights into gene regulation.

Gill Elliottمشاهده پروفایل

استاد

• Virology
• Molecular Biology
• Herpesvirus Pathogenesis
• +۴ مورد دیگر

Professor Gill Elliott is a Professor of Virology at the University of Surrey, based in the Department of Microbial and Cellular Sciences within the Faculty of Health and Medical Sciences. Her research focuses on the cell biology of herpes simplex virus (HSV) infection, particularly how HSV hijacks cellular machinery to assemble viral particles. She has held academic positions at institutions including the University of Leeds, Marie Curie Research Institute, and Imperial College London, with a career spanning over three decades in virology research. After completing a BSc in Microbiology at Queen's University Belfast, she earned her PhD working on the molecular biology of mumps virus. Her postdoctoral research at the University of Oxford explored HIV transcription mechanisms, leading to her Wellcome Trust-funded work on herpesviruses at the University of Leeds. Key career milestones include a MRC Senior Non-Clinical Fellowship at Imperial College London before joining the University of Surrey in 2013. Her research group investigates HSV's exploitation of the cellular secretory pathway during assembly, viral-host interactions, and antiviral target identification. They employ advanced techniques like live-cell imaging and siRNA depletion. Notable achievements include defining roles for VP22 and VHS proteins in transcriptome remodeling and viral assembly dynamics. Recent grants include £500,000 awarded in 2019 to investigate HSV pathogenesis. Her work bridges fundamental virology with clinical applications, aiming to combat HSV's global health impact through antiviral development.

Arianna Baggioliniمشاهده پروفایل

استادیار

• Cancer Biology
• Neuroscience
• Stem Cell Biology
• +۳ مورد دیگر

Arianna Baggiolini is an Assistant Professor at the Università della Svizzera italiana (USI), affiliated with the Institute of Oncology Research (IOR) in the BIOS+ network. She leads an independent research group focusing on melanoma oncogenic competence, developmental chromatin programs, and stem cell biology. Previously, she completed a postdoctoral fellowship at Memorial Sloan Kettering Cancer Center (MSKCC) under Dr. Lorenz Studer, where she explored neural crest development and melanoma formation. Her education includes a BSc and MSc in Biology from ETH Zurich and a PhD in Neuroscience from the University of Zurich. Key contributions include defining oncogenic competence in melanoma and elucidating roles of developmental chromatin factors in tumor initiation and neural maturation. Baggiolini’s research integrates cancer biology, stem cell engineering, and developmental pathways to uncover mechanisms underlying tumor progression and therapeutic vulnerabilities. Her work has been recognized with prestigious awards such as the Christopher J. Marshall Award (Society for Melanoma Research), SNSF Starting Grant, and the Hofschneider Professorship. Current research emphasizes lipid metabolism in melanoma, epigenetic barriers to neuronal maturation, and translational approaches to modulate glial cells in spinal cord injury. Baggiolini’s lab employs cutting-edge techniques like patient-derived organoids and CRISPR-based models to study tumor heterogeneity and cellular plasticity. She actively collaborates on projects addressing neurodevelopmental disorders and cancer stem cell therapies, with a focus on translating basic discoveries into clinical applications.

Paola A. Marignaniمشاهده پروفایل

استاد

• Cancer Metabolism
• Tumor Suppressor Proteins
• Signal Transduction
• +۵ مورد دیگر

Paola A. Marignani is a Professor in the Departments of Biochemistry and Molecular Biology and Pathology at Dalhousie University's Faculty of Medicine. She has been a department member since 2003, following postdoctoral fellowships at Harvard University and the Samuel Lunenfeld Research Institute/Ontario Cancer Institute. Her research focuses on tumor suppressors, cancer metabolism, and signal transduction, with a particular emphasis on LKB1 and Vav2 proteins. She holds a PhD in Biochemistry from McMaster University and an Executive MBA from Ivey School of Business. Education: Hon BSc, University of Windsor MSc, University of Western Ontario PhD, McMaster University Executive MBA, Ivey School of Business, Western Ontario Research Interests: The Marignani Lab investigates molecular mechanisms underlying cancer progression and neurodegenerative diseases. Key areas include: LKB1's role in tumor suppression and metabolic regulation Vav2's influence on cytoskeletal reorganization Pre-clinical drug development using animal models Single-cell genomic analysis (scRNA-seq, scATAC-seq) Funding Sources: Supported by Dalhousie Medical Research Foundation, CIHR, NSERC, and others. Current projects include biomarker identification and targeted therapeutics. Labs & Teams: The Marignani Discovery Research Laboratory employs advanced platforms such as metabolomics, epigenomics, and CRISPR-based gene editing. Lab members include postdocs, technicians, and students, with notable former trainees like Jacob Rukavina and Ramani Soundararajan.

Behzad Toosiمشاهده پروفایل

استادیار

• Comparative Oncology
• Cancer Biology
• Translational Research
• +۲ مورد دیگر

Behzad Toosi is the Allard Research Chair in Oncology and an Assistant Professor in the Department of Small Animal Clinical Sciences at the University of Saskatchewan's Western College of Veterinary Medicine. He holds a DVM from Ferdowski University of Mashad (2002), a PhD in Veterinary Biomedical Sciences (2009), and completed two postdoctoral fellowships at USask. His research focuses on comparative oncology, targeting cancers like lymphoma, osteosarcoma, and melanoma through Eph receptor signaling and translational models. Dr. Toosi leads the Comparative Oncology Research Group (CORG), leveraging naturally occurring tumors in dogs to accelerate human cancer therapeutic discovery. His recent publications explore PLK1 vulnerabilities, Eph receptor crosstalk, and bispecific antibodies. Research emphasizes drug sensitivity mechanisms, radiopharmaceutical delivery, and kinase-independent tumor suppression. Awards include the Allard Research Chair for pioneering comparative oncology approaches. Key article themes include receptor tyrosine kinase signaling in cancer progression (Eph/EGFR), innovative therapeutic strategies (bispecific antibodies, radiometalated peptides), and mechanistic insights into chemosensitivity. Canine models bridge translational gaps in osteosarcoma and lymphoma research.

Nadine Vastenhouwمشاهده پروفایل

دانشیار

• Developmental Biology
• Molecular Biology
• Genomics
• +۳ مورد دیگر

Nadine Vastenhouw is an Associate Professor at the University of Lausanne's Center for Integrative Genomics (CIG), part of the Faculty of Biology and Medicine. She leads a research group focusing on transcriptional regulation during vertebrate embryogenesis, particularly in zebrafish. Her work explores how chromatin structure and transcriptional machinery interact to regulate embryonic development during the maternal-to-zygotic transition. She has held positions at Harvard University, the Max Planck Institute in Dresden, and joined UNIL in 2020. Her research is funded by organizations including EMBO, HFSP, NIH, and the Max Planck Society. Education: Masters in Medical Biology, Amsterdam PhD at Hubrecht Institute (Utrecht), studying RNA interference in C. elegans Postdoctoral research at Harvard University, investigating zebrafish embryology Research Interests: Her lab combines molecular biology, genomics, and biophysics to study how transcriptional programs are established during early embryonic development. Key areas include: Chromatin dynamics during genome activation Role of epigenetic factors in developmental transitions Mechanisms linking maternal and zygotic gene expression Labs & Teams: She leads the Vastenhouw Lab at CIG, located in Lausanne. The lab focuses on interdisciplinary approaches to understand transcriptional regulation in zebrafish embryos.

Aleksandar Vjesticaمشاهده پروفایل

استادیار

• Cell Biology
• Developmental Biology
• Genetics
• +۳ مورد دیگر

Aleksandar Vjestica is a tenure-track Assistant Professor at the University of Lausanne's Faculty of Biology and Medicine, affiliated with the Center for Integrative Genomics. His research focuses on understanding how fertilization triggers the transition from gamete to zygote in fission yeast (Schizosaccharomyces pombe), exploring mechanisms of zygotic fate establishment, mating blocks, and genomic activation. Key topics include cell cycle regulation, reproductive barriers, and transcriptional reprogramming post-fertilization. Research emphasizes the sexual lifecycle's universal ploidy cycle, using yeast's experimental tractability to uncover conserved mechanisms across eukaryotes. Notable findings include the role of transcription factors in blocking re-fertilization and parental genome bias in zygotes. The lab employs advanced microscopy, optogenetics, and genetic tools to study these processes. Publications highlight contributions to membrane dynamics, cell polarity, and stress response pathways in yeast. The group's work bridges fundamental biology with evolutionary principles, aiming to uncover principles applicable to higher organisms like plants and animals. No scientific awards are explicitly listed, though the research's prestige suggests potential recognition. The lab collaborates actively within the University of Lausanne's scientific community, with administrative support provided by Melinda Mischler. Research is centered at the Génopode facility in Lausanne, Switzerland.

• Plant Abiotic Stress Responses
• Molecular Genetics of Stress Tolerance
• Post-Transcriptional Regulation
• +۷ مورد دیگر

Giorgia Batelli is a Senior Researcher at the Institute of Biosciences and Bioresources (IBBR), part of the National Research Council of Italy (CNR), based at the Portici branch. She is a prominent scientist in the field of plant molecular biology, with a strong focus on abiotic stress responses, particularly drought and salinity, in crops like tomato and potato. Full Name: Giorgia Batelli Institution: National Research Council of Italy (CNR) Research Institute: Institute of Biosciences and Bioresources (IBBR) Division: Portici Branch Position: Senior Researcher Email: giorgia.batelli@cnr.it PhD: University of Naples, Federico II (2007) Her research interests lie in understanding the molecular and genetic mechanisms that enable plants to tolerate environmental stresses. She investigates post-transcriptional and post-translational regulation, epigenetic control, and genetic networks involved in stress tolerance, using model systems like Arabidopsis thaliana and crop species such as tomato and potato. Her work integrates forward and reverse genetics, RNA silencing, and omics technologies, including transcriptomics and single-cell analysis, to identify key genes and regulatory pathways for improving crop resilience. The trends in her recent publications show a consistent focus on the molecular basis of plant stress responses. Her work spans from fundamental studies on ABA signaling and protein phosphatases to applied research on identifying stress-tolerant genotypes in tomato landraces and wild relatives. A significant theme is the role of alternative splicing and RNA-binding proteins in stress adaptation. Her research has a strong translational component, aiming to provide genetic resources and knowledge for breeding more resilient crops in the face of climate change. Giorgia Batelli has authored or co-authored numerous scientific publications in high-impact journals such as Plant Cell , BMC Plant Biology , Frontiers in Plant Science , and Proceedings of the National Academy of Sciences . She has also contributed to book chapters on topics like drought stress tolerance and plant adaptation to environmental stress. She has been actively involved in mentoring and collaborative research, working closely with colleagues such as Alessandra Ruggiero, Stefania Grillo, and Michael James Van Oosten. Her research has been supported by various projects focused on improving plant resilience and resource use efficiency. She is a key member of a research group dedicated to mining genetic and epigenetic resources from wild and traditional plant varieties for crop improvement.

Matt Steensmaمشاهده پروفایل

دانشیار

• Sarcomas
• Neurofibromatosis Type 1 (NF1)
• Tumor Progression
• +۳ مورد دیگر

Dr. Matt Steensma is an Associate Professor in the Department of Cell Biology at Van Andel Institute (VAI). He leads the Steensma Laboratory, focusing on developing treatment strategies for sarcomas and neurofibromatosis type 1 (NF1). His work integrates molecular biology, translational research, and clinical insights to address aggressive cancers like bone and soft-tissue sarcomas. Education: B.A. from Hope College, M.D. from Wayne State University School of Medicine. Completed residency in orthopaedic surgery and fellowship in musculoskeletal oncology at Memorial Sloan Kettering Cancer Center. Joined VAI in 2010 as an Associate Scientific Investigator, later becoming a Francis S. Collins Scholar in Neurofibromatosis Research (2014). Research interests include tumor progression mechanisms in NF1, epigenetic alterations in neurofibromas, and metabolic reprogramming in cancer. His lab employs genetically engineered mouse models, patient-derived explants, and next-gen sequencing. Key focus areas are identifying therapeutic targets and overcoming chemotherapy resistance. Publications highlight NF1’s role in breast cancer, sarcoma genomics, and drug response. Collaborative grants include a 2013 Wells Fargo Foundation award for rare disease research. His team includes PhD students, postdocs, and technicians addressing clinical translation challenges. Awards: Francis S. Collins Scholar (2014). Lab impact includes 122 peer-reviewed papers in 2024, contributions to VAI-SU2C clinical trials, and collaborations with institutions like Memorial Sloan Kettering and Michigan State University.

Suneet Agarwalمشاهده پروفایل

دانشیار

• Telomere Biology Disorders
• Bone Marrow Failure
• Mitochondrial DNA Disorders
• +۱۲ مورد دیگر

Suneet Agarwal, MD, PhD, is Associate Professor of Pediatrics at Harvard Medical School and Co-Program Leader for the Stem Cell Transplant Center at Dana-Farber/Boston Children's Cancer and Blood Disorders Center. His work bridges clinical pediatrics, hematology-oncology, and translational research in bone marrow failure and telomere biology disorders. Medical School: Harvard Medical School, 2001 Internship: Boston Children's Hospital, 2002 Residency: Pediatrics, Boston Combined Residency Program (BCRP), 2003 Fellowship: Pediatric Hematology-Oncology, Dana Farber Cancer Institute/Children's Hospital Boston, 2006 Dr. Agarwal’s research focuses on telomere biology disorders , mitochondrial DNA deletion disorders , and inherited bone marrow failure syndromes . He employs induced pluripotent stem cells (iPSCs), gene editing, and molecular techniques to model diseases and develop therapies, including small-molecule PAPD5 inhibitors for telomere restoration. His lab investigates nucleotide metabolism, telomere length control, and heteroplasmy dynamics in mitochondrial disorders. His recent publications reveal a strong thematic focus on telomere regulation, stem cell biology, and hematopoietic transplantation. Key trends include the role of nucleotide salvage in telomere maintenance, molecular mechanisms of telomere disease, and clinical outcomes in stem cell transplant for myelodysplastic syndrome and telomere disorders. His work frequently appears in top-tier journals such as Nature Genetics , Cell Stem Cell , and Blood . Scientific contributions include: Discovery of PAPD5 inhibitors that restore telomerase activity in patient stem cells Mechanistic insights into TERC and TERT variants in telomere diseases Characterization of liver and vascular complications in dyskeratosis congenita Development of iPSC models for rare genetic blood disorders Dr. Agarwal leads a research lab at Dana-Farber/Boston Children's and is actively involved in mentoring and scientific innovation. He has not publicly listed specific advisees or awards, but his research program is supported by extensive publications and clinical leadership. He is not indicated to be part-time, retired, or deceased. His laboratory, the Suneet Agarwal Lab , is dedicated to understanding the molecular basis of genetic blood disorders and developing regenerative and pharmacological therapies. The lab utilizes cutting-edge technologies including single-cell multi-omics, genome editing, and stem cell reprogramming to uncover disease mechanisms and therapeutic targets.

• Neuropsychiatric Disorders
• Structural Variation
• Genomics
• +۳ مورد دیگر

Dr. Alexander Urban is an Assistant Professor at the Child Study Center and Department of Genetics at Yale School of Medicine. His research focuses on structural genomic variations, transcriptomic and epigenomic reprogramming in neuropsychiatric disorders, and neurodevelopmental mechanisms. Key research areas include: Elucidating structural variation in human genomes across populations Investigating 16p11.2 and 22q11.2 deletion mechanisms Mapping transcriptomic and epigenomic changes in induced neurons Developing regulatory element atlases for human brain development Recent publications highlight his work on: Single-cell genomics across 388 human brains Chromosomal rearrangement dynamics in psychiatric disorders Cross-ancestry gene regulation studies in neurodevelopment Functional characterization of regulatory elements in cortical development