Patrick J. Murphy

Patrick J. Murphy is an Assistant Professor in the Department of Biology at the University of Rochester’s School of Arts & Sciences. His research focuses on mechanisms governing gene expression during development and disease, particularly using zebrafish and mammalian models to study epigenetic regulation of cell identity transitions. He earned a PhD and holds expertise in chromatin dynamics, developmental genomics, and bioinformatics.

Research Interests include:

• Regulation of vertebrate gene transcription in vivo
• Epigenetic and chromatin dynamics
• Zebrafish genetics & genomics
• Developmental cell state transitions
• Advanced genomic technologies

Publications span topics like histone chaperones in neurons, pluripotency reacquisition, and paternal epigenetic effects of smoking. His work combines classic developmental biology with modern genomics and bioinformatics tools.

No scientific awards are explicitly listed, though his high-impact publications reflect significant contributions. Advising no listed students, but collaborates on projects involving chromatin and epigenetic reprogramming. Active in the Murphy Lab, which leverages zebrafish systems for mechanistic insights into gene regulation.