جستجوی استاد راهنمای دانشگاهی

Dawn Belt Davisمشاهده پروفایل

استاد

• Endocrinology
• Diabetes
• Obesity
• +۵ مورد دیگر

Dawn Belt Davis, MD, PhD, is a physician-scientist at the University of Wisconsin–Madison, holding a co-appointment at the William S. Middleton Memorial VA Hospital. She is affiliated with the Department of Medicine within the School of Medicine and Public Health, where she leads a federally funded research laboratory focused on pancreatic beta cell biology. Her work spans both clinical and basic science domains, particularly in diabetes, obesity, and metabolic surgery outcomes. MD and PhD in Pathology, University of Chicago Internal Medicine Residency, University of Washington Medical Center Fellowship in Endocrinology, Diabetes, and Metabolism, University of Wisconsin Hospitals and Clinics Dr. Davis’s research is centered on understanding the mechanisms of beta cell proliferation and apoptosis, with a strong emphasis on cholecystokinin, FoxM1, and TCF19 as regulators of beta cell survival. Her clinical investigations explore metabolic changes following Roux-en-Y gastric bypass, including postprandial hypoglycemia and insulin sensitivity. She has made significant contributions to understanding the role of prostaglandin signaling, lipid metabolism, and immune modulation in islet function and diabetes pathogenesis. Analysis of her recent publications reveals a consistent focus on translational endocrinology, particularly the interplay between metabolic signals and beta cell fate. Her work increasingly integrates metabolomics, lipidomics, and molecular signaling to uncover novel pathways in diabetes. She frequently collaborates with researchers such as Dr. Kimple, Dr. Merrins, and Dr. Attie, reflecting a highly collaborative research environment. Dr. Davis has not received public recognition in the form of listed scientific awards in the provided texts, but her sustained funding and high-impact publications indicate significant scientific contributions. She has been involved in clinical trials, such as the PREVENT study on avexitide for postbariatric hypoglycemia, demonstrating her engagement in therapeutic development. She mentors within a vibrant research community at the VA hospital’s 4C wing, which hosts multiple endocrine research groups, fostering daily scientific exchange and collaboration. Her lab environment supports training for scientists at all levels, and she contributes to educational pathways for medical trainees interested in research.

Frank Kjeldsenمشاهده پروفایل

استاد

• Proteomics
• Mass Spectrometry
• Nanoparticle-Biological Interactions
• +۷ مورد دیگر

Frank Kjeldsen is a Professor and group leader in the Protein Research group at the Department of Biochemistry and Molecular Biology , University of Southern Denmark . His research focuses on proteomics, mass spectrometry, and the biological effects of nanoparticles, with a strong emphasis on method development in negative ion mode and ultrafast proteomic platforms. His research interests span: Proteomics and systems biology Nanoparticle-biological system interactions Development of novel mass spectrometry and chemical biology methods Fundamental gas-phase peptide chemistry Metabolomics and multi-omics integration Recent publications (2023–2025) highlight trends in ultrafast proteomics , multi-omics for environmental and biomedical applications, nanoplastic toxicity , and neuroprotection . His work frequently involves advanced LC-MS/MS techniques, ion mobility, and software development for data analysis. Scientific recognition includes: 2 prizes (as noted in his CV profile) He actively supervises research and collaborates on multiple interdisciplinary projects. His lab, the Frank Kjeldsen Lab , is part of the Biomedical Mass Spectrometry research section. He has contributed to numerous grants and collaborative research efforts in toxicology, cancer, and environmental science.

Hilary Browneمشاهده پروفایل

پژوهشگر ارشد

• Gut Microbiota Ecology
• Anaerobic Microbiology
• Bacterial Spore Formation
• +۳ مورد دیگر

Dr. Hilary Browne is a Research Fellow at the School of Microbiology and APC Microbiome Ireland at University College Cork (UCC). He holds a PhD from the London School of Hygiene and Tropical Medicine, with prior roles at the Wellcome Sanger Institute including Staff Scientist and Senior Staff Scientist. His research focuses on gut microbiota adaptations, particularly the role of bacterial spore formation in transmission and colonization. He leads a team using anaerobic microbiology, genomics, and metagenomics to study spore-forming bacteria's metabolic properties and genetic architecture. Dr. Browne's academic journey includes a BSc in Agricultural Science (UCD) and MSc in Biotechnology (UCC). He was awarded the Garnham Award for doctoral research in basic laboratory science. In 2023, he secured an ERC Starter Grant to establish his independent research group, advancing translational microbiome research. His research explores mechanisms enabling gut bacteria to survive host transitions, with implications for probiotic development and therapeutic delivery. Key areas include spore-mediated survival strategies, microbiome assembly in infants, and antibiotic resistance dynamics in human microbiota. Dr. Browne contributes to global health initiatives through collaborations like the CHAIN network, focusing on child mortality in sub-Saharan Africa using multi-omics approaches. His work bridges fundamental microbiology with clinical applications, emphasizing the microbiome's role in health and disease.

Niall Hylandمشاهده پروفایل

استاد

• Gut-Brain Axis
• Microbiome Research
• Gastrointestinal Physiology
• +۴ مورد دیگر

Prof Niall Hyland is a Professor in the Department of Physiology at University College Cork (UCC) and a Funded Investigator at APC Microbiome Ireland. He holds a BSc (Hons) in Biomedical Sciences from the University of Ulster and a PhD in Pharmacology from King’s College London. After postdoctoral fellowships at Louisiana State University and the University of Calgary, he joined UCC in 2008 as a Lecturer and was promoted to Professor in 2025. Research Interests: His work focuses on the gut microbiota's role in gastrointestinal physiology, the gut-brain axis, probiotics, colon cancer, and drug-microbiome interactions. Techniques include Ussing chamber analysis, in vivo disease models, and collaborations on implantable bioelectronics for enteric neural monitoring. Grants & Collaborations: He has secured over €3.3M in funding from agencies like Science Foundation Ireland and Horizon 2020. Collaborators include the University of Cambridge, Alimentary Health Ltd., and industry partners like GlaxoSmithKline. Awards & Roles: Honorary Fellowship (British Pharmacological Society, 2022). Leadership roles include Chair of the Probiota Global Event Scientific Committee and Co-Chair of the BPS Systems and Integrative Pharmacology Group. Labs & Teams: Leads a lab at APC Microbiome Ireland, focusing on microbiome interventions and host physiology. Collaborates with multidisciplinary teams on projects like the RELATE EU initiative and drug-gut microbiota interaction studies.

• Cancer Research
• Immunology
• Hematology
• +۵ مورد دیگر

Dr Vasilios Panagopoulos is an NHMRC Ext-Funded Research Fellow and Group Leader at the University of South Australia (UniSA), holding an Affiliate Senior Lecturer role at the University of Adelaide and a Faculty Fellowship at SAHMRI. His research focuses on the tumor microenvironment's role in cancer progression, particularly in prostate, breast, and multiple myeloma cancers. He leads the Prostate Tumour Microenvironment and Therapeutics Lab under Prof. David Waugh, aiming to translate findings into clinical applications. Research Interests : - Prostate cancer immunosuppression via IKKα inhibition and MPO regulation. - Vitamin D analogues for aggressive breast cancer. - Bone marrow microenvironment in multiple myeloma progression. - Novel therapies targeting stromal factors like Gremlin1 and CCR1. Awards and Funding : - Secured $1.8M in competitive grants (NHMRC, Cancer Australia). - 2021 Derek Frewin Early-Career Researcher Award. - 2017 Ross Wishart Memorial Award. - Multiple travel grants for conference presentations. Collaborations : - Global partnerships with Oxford University, AstraZeneca, and Washington University. - National collaborations with Garvan Institute and UniSA. Lab and Teams : Leads the Prostate Tumour Microenvironment and Therapeutics Lab, focusing on IKKα inhibitors, vitamin D analogues, and MPO inhibition. Active in drug development with clinical trial initiatives (e.g., Gremlin1 antibody therapy in Phase I).

Nadia Schoenmakersمشاهده پروفایل

استاد

• Endocrinology
• Genetic Basis of Thyroid Disorders
• Congenital Hypothyroidism
• +۴ مورد دیگر

Professor Nadia Schoenmakers is a clinician-scientist at the University of Birmingham, holding the 125th Anniversary Chair in the Department of Metabolism and Systems Science. She specializes in endocrinology, focusing on congenital thyroid disorders, particularly congenital hypothyroidism (CH) and central congenital hypothyroidism (CeCH). Her research integrates genetic, environmental, and clinical approaches to understand thyroid development, hormone synthesis, and disease mechanisms. Education and Training: MB BChir, University of Cambridge (2001) PhD in Molecular Endocrinology, University of Cambridge (2012) CCT in Endocrinology, Diabetes, and General Internal Medicine (2012) Research Interests: Genetic basis of thyroid disorders Environmental contributors to CH (e.g., micronutrients, endocrine disruptors) Phenotypic characterization of CH/CeCH patients Thyroid hormone action mechanisms Single-cell transcriptomics of thyroid tissues Her work bridges basic science and clinical practice, aiming to improve diagnostics and patient outcomes. Professional Activities: Secretary, British Thyroid Association (2024–present) Leadership roles in European and international endocrine societies Collaborations with institutions like the Wellcome Sanger Institute and Great Ormond Street Hospital Grants and Funding: Wellcome Intermediate Clinical Fellowship Wellcome Senior Research Fellowship (2020–present) Labs and Teams: Active collaboration with the Birmingham Thyroid Group and the Cambridge National Service for unusual thyroid disorders. Maintains clinical ties via honorary consultant roles at University Hospitals Birmingham and Addenbrooke’s Hospital.

Craig Leeمشاهده پروفایل

استاد

• Pharmacogenomics
• Cardiovascular Therapeutics
• Drug Metabolism
• +۳ مورد دیگر

Craig Lee is a John A. and Deborah S. McNeill, Jr. Distinguished Professor and Chair of the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy. He holds adjunct appointments in the UNC School of Medicine’s Division of Cardiology and is a member of the McAllister Heart Institute and Program for Precision Medicine in Healthcare. Education: Pharm.D. (UNC-Chapel Hill, 2000), Ph.D. in Pharmaceutical Sciences (UNC-Chapel Hill, 2006), and a Fellowship in Clinical Research/Drug Development (UNC/ GlaxoSmithKline). His research focuses on precision medicine, cytochrome P450 metabolism, and cardiovascular therapeutics. Key areas include genotype-guided antiplatelet therapy, pregnancy drug metabolism, and CYP-derived eicosanoids in cardiometabolic disease. Over 100 manuscripts and abstracts highlight his translational work integrating preclinical and clinical models. Recent studies emphasize optimizing drug selection/dosing via pharmacogenomics, particularly in high-risk PCI patients and pregnant populations. Collaborations with NIH-funded projects and multi-institutional registries drive his work. Grants: NIH/NHLBI Precision PCI Registry, NIH/NICHD pregnancy metabolism studies. Awards: Over 40 students advised (PhD, postdocs, PharmD). Labs: Craig Lee Lab focuses on precision medicine, pregnancy pharmacology, and eicosanoid pathways.

Dieter Saurمشاهده پروفایل

استاد

• Translational Cancer Research
• Genetic Alterations in Cancer
• Personalized Medicine
• +۳ مورد دیگر

Prof. Dieter Saur is a Professor of Translational Tumor Research at the Technical University of Munich (TUM) and Head of the Department at the German Cancer Research Center (DKFZ). His research focuses on developing personalized cancer therapies through mechanistic studies of tumor-relevant genetic alterations, with a particular emphasis on pancreatic and gastrointestinal cancers. Education: Studied medicine at Ludwig Maximilian University of Munich, earned a doctorate in neurogastroenterology, completed specialist training in gastroenterology and gastrointestinal oncology, and habilitation in internal medicine. He became a senior physician at University Hospital rechts der Isar before his current roles at TUM and DKFZ. Research Interests: Translational cancer research, genetic drivers of tumor progression, early detection methods, and targeted therapies for pancreatic and gastrointestinal cancers. He uses genetically engineered mouse models and organoid systems to study tumor heterogeneity and therapeutic resistance. Awards: Recipient of prestigious grants like the ERC Consolidator Grant (2015) and awards such as the Martin Wienbeck Award (2014) and Rising Star Award (2006). His work bridges basic science and clinical translation, emphasizing interdisciplinary approaches. Labs/Teams: Leads the Translational Tumor Research group at TUM and collaborates with the DKFZ to advance preclinical and clinical cancer research. Key projects include exploring KRAS signaling pathways, tumor microenvironment dynamics, and immune checkpoint therapies.

Ali Ünlüمشاهده پروفایل

استاد

• Mathematical and statistical methods
• Behavioral sciences
• Educational research
• +۳ مورد دیگر

Prof. Ali Ünlü is a full professor in Methods of Empirical Educational Research at the Technical University of Munich (TUM), affiliated with the TUM School of Social Sciences and Technology. His research focuses on mathematical and statistical methods in behavioral sciences, educational measurement, and large-scale assessment. He earned his mathematics degree from TU Darmstadt (2000), a doctorate in psychometrics from TU Graz (2004), and habilitation in statistics from the University of Augsburg (2009). Awards include the 2005 Memorial Guest award from Purdue University. His work emphasizes latent variable models for knowledge assessment and has been published in journals like Methodology and Journal of Mathematical Psychology . He has held visiting professorships and led the Center for International Comparative Educational Studies (2011–2016). His recent studies explore β-cell biology and diabetes mechanisms, reflecting interdisciplinary research interests. Education: PhD in Psychometrics/Mathematical Psychology (2004) Habilitation in Statistics (2009) Research emphasizes quantitative methodologies applied to educational and behavioral sciences. Key themes include: Statistical modeling in large-scale assessments Latent variable models for competence diagnostics Interdisciplinary cell biology studies (e.g., β-cell dynamics) Recent publications highlight cellular mechanisms in diabetes and pancreatic development. His work bridges educational measurement and biomedical research, leveraging advanced statistical techniques. Awards: Winner Memorial Guest, Purdue University (2005) Grants and advisory roles include leadership at the Center for International Comparative Educational Studies. Collaborations span institutions like UC Irvine and Purdue University.

• Developmental Biology
• Regenerative Medicine
• Cardiovascular Development
• +۳ مورد دیگر

Mathilda Mommersteeg is an Associate Professor of Developmental and Regenerative Medicine at the University of Oxford's Department of Physiology, Anatomy & Genetics (DPAG), and Deputy Director of Graduate Studies at St Cross College. She holds a PhD from the University of Amsterdam (2009) and conducted postdoctoral research at University College London (UCL), supported by an EMBO fellowship. Her work focuses on understanding molecular mechanisms underlying heart regeneration and development, particularly using zebrafish and Mexican cavefish models. Key research areas include Slit-Robo signaling pathways, cardiac innervation, and the genetic basis of regenerative success. Her research has identified critical roles for genes like Lrrc10 and Runx1 in heart regeneration, and she has pioneered studies on population-specific differences in regenerative capacity between surface and cave-dwelling Mexican cavefish. Mommersteeg's contributions span developmental cardiology, regenerative biology, and comparative genomics, with a focus on translating findings to improve human cardiac repair strategies. Education: PhD in Developmental Biology, University of Amsterdam (2009) Labs/Groups: Mommersteeg Group (Oxford) Grants/Funding: Supported by the British Heart Foundation (BHF) and other initiatives Her recent work emphasizes the interplay between cardiomyocyte proliferation and fibrotic responses in regeneration failure, with studies revealing how genetic and environmental factors influence repair outcomes.

Anne Fultonمشاهده پروفایل

استاد

• Pediatric Ophthalmology
• Retinal Degeneration
• Genetic Eye Disorders
• +۳ مورد دیگر

Anne B. Fulton, MD, is a Professor at Harvard Medical School and Director of the Pediatric Medical Retinal Service at Boston Children's Hospital. She holds dual roles in clinical practice and research, focusing on pediatric ophthalmology and retinal disorders. Her affiliations include the Department of Ophthalmology at Harvard and leadership in the Precision Medicine Service. Dr. Fulton earned her MD from Tufts University School of Medicine, followed by residency at Yale University School of Medicine. Her research emphasizes retinal development, retinopathy of prematurity (ROP), and genetic eye disorders. She pioneered non-invasive assessments like visual electrophysiology and adaptive optics imaging to study pediatric vision. Her research interests span retinal degeneration mechanisms, photoreceptor maturation, and inherited retinal diseases. Over 30 years of NIH-funded work has led to breakthroughs in understanding rhodopsin's role in visual development and ROP pathophysiology. Recent studies include algorithm validation for ROP diagnosis and genetic basis of retinal dystrophies. Dr. Fulton’s articles highlight advancements in ROP treatment protocols, genetic syndromes (e.g., Bardet-Biedl), and adaptive imaging techniques. Though no named awards are listed, her sustained NIH funding underscores her research impact. She advises on NIH grants and collaborates with teams at Boston Children's Hospital’s Infant Vision Laboratory. Labs/Teams: Infant Vision Laboratory, Precision Medicine Service. Her work bridges clinical care and translational research to improve outcomes for pediatric retinal patients.

Wentao Liمشاهده پروفایل

استادیار

• DNA Damage and Repair
• Mutagenesis
• Genomics
• +۳ مورد دیگر

Dr. Wentao Li is an Assistant Professor in the Department of Environmental Health Science at the University of Georgia's College of Public Health. His research focuses on mechanisms of DNA damage, repair, and mutagenesis across organisms from yeast to humans, employing genomics, biochemistry, bioinformatics, and machine learning. He leads the Li Laboratory, actively recruiting postdoctoral researchers and graduate students in bioinformatics and molecular biology. Dr. Li's work has been recognized with prestigious awards, including the 2024 SOT/AACT Outstanding Young Toxicologist Award and the 2023 James A. Swenberg Carcinogenesis Merit Award. Research interests include understanding how DNA repair processes interact with 3D genome organization, mitochondrial DNA fragmentation under UV damage, and the role of xenophagy in pathogen infections. His lab collaborates on projects involving aflatoxin-induced damage, transcription-coupled repair mechanisms, and comparative repair dynamics in bats versus humans. Publications highlight contributions to nucleotide excision repair mapping, UV damage effects, and computational models like Gp-gpt for gene-phenotype mapping. Awards also include the 2023 EMGS Newly Independent Investigators Engagement Program and a 2024 Presidential Graduate Fellowship for student Shan Jiang. Dr. Li oversees lab operations at the Paul D. Coverdell Center, with a focus on mentoring over a dozen students and technicians.

Rihab Boucharebمشاهده پروفایل

استادیار

• Cardiovascular Sciences
• Metabolic Disease Research
• Heart Valve Disease
• +۷ مورد دیگر

Rihab Bouchareb, PhD, is an Assistant Professor at the Center for Metabolic Disease Research within the Lewis Katz School of Medicine at Temple University. Her work bridges cardiovascular sciences and renal pathophysiology, focusing on translational approaches to understanding and treating cardio-renal diseases. PhD in Physiology and Biology of Organisms and Population Interactions, Strasbourg University, France (2008–2012) Master's in Molecular and Cell Physiology, Strasbourg University, France (2006–2008) B.A. in Biochemistry, Blida University, Algeria (2000–2004) Dr. Bouchareb's research centers on the molecular mechanisms driving calcific aortic valve stenosis and acute kidney injury, with a focus on metabolic dysfunction, inflammation, mitochondrial damage, and platelet involvement. She is pioneering mitochondrial transplantation as a regenerative strategy for kidney repair. Her work integrates molecular biology , systems medicine , and clinical relevance to identify novel therapeutic targets. The most recent publications reflect a strong trend in cardiovascular calcification , mitochondrial dysfunction , inflammatory pathways , and genetic/proteomic biomarker discovery . Her studies span experimental models, human tissue analysis, and clinical correlations, often published in high-impact journals such as Circulation , Nature Metabolism , and European Heart Journal . Scientific Awards and Recognitions: Multiple best presentation and research awards from Canadian Cardiovascular Society and Quebec Heart and Lung Institute (2013–2018) Team Science Award, Dr Jason Kovacic Lab, Mount Sinai (2019) Promising Young Investigator and Young Investigator Travel Awards (2020, 2022) Marquis Who's Who in America (2023) NIH-ISAC Innovation Science Accelerator Program (2024) Dr. Bouchareb has been involved in significant collaborative research grants and projects, particularly in fibromuscular dysplasia, valve degeneration, and diabetic kidney disease. She has contributed to methodological advances in cell isolation and imaging. Her work is supported by active collaborations with leading institutions and researchers in cardiology and nephrology. She is affiliated with the American Heart Association and has contributed to interdisciplinary research teams and labs focused on metabolic disease, cardiovascular repair, and translational innovation.

• Genetics
• Translational Genomics
• Neurodegenerative Diseases
• +۷ مورد دیگر

Arturo Lopez Castel is an Assistant Professor in the Department of Genetics at the Faculty of Biological Sciences, Universitat de València, where he is a key member of the Human Translational Genomics research group and affiliated with the Institute of Biotechnology and Biomedicine (BIOTECMED). His work bridges fundamental genetic mechanisms with translational applications in neuromuscular disorders. His research centers on the molecular basis of nucleotide repeat expansion diseases, especially myotonic dystrophy types 1 and 2. Using Drosophila melanogaster as a model organism, he investigates genomic instability, DNA repair deficiencies, and RNA toxicity mechanisms. His studies extend to patient-derived cell lines and mouse models, enabling a comprehensive approach from bench to bedside. Key areas include CTG/CAG repeat instability, epigenetic modifications like CpG methylation, and the role of microRNAs in muscle atrophy. Analysis of his recent publications reveals a strong trajectory in both mechanistic and therapeutic research. He has pioneered in vivo screening platforms, explored natural compounds such as boldine and stephanantherine for treatment, and contributed to understanding parent-of-origin effects in congenital transmission. His work integrates omics technologies and molecular pathology to identify novel biomarkers and therapeutic targets. While no scientific awards are mentioned in the provided text, his sustained publication record in high-impact areas underscores his contributions to the field. He has supervised thesis work and is actively involved in drug development pipelines for myotonic dystrophy, reflecting a commitment to both academic mentorship and clinical translation. Dr. Lopez Castel leads research within the GT Human Translational Genomics group, leveraging collaborative networks and multidisciplinary approaches to tackle complex genetic disorders. His lab combines genetic models, molecular assays, and pharmacological testing to advance understanding and treatment of repeat expansion diseases.

John Aitchisonمشاهده پروفایل

استاد مدعو

• Systems Biology
• Cell Biology
• Systems Cell Biology
• +۷ مورد دیگر

John Aitchison is an Adjunct Professor affiliated with the Institute for Systems Biology and the Center for Infectious Disease Research in Seattle, Washington. He holds a Ph.D. from McMaster University and leads a research program in systems cell biology, focusing on the integration of molecular, genomic, and computational approaches to understand cellular complexity. Adjunct Professor, Institute for Systems Biology, Seattle Ph.D., McMaster University Dr. Aitchison’s research centers on systems cell biology, with key interests in nucleocytoplasmic transport, peroxisome biogenesis, and host-pathogen interactions. His lab employs functional genomics, proteomics, and computational modeling to dissect the molecular mechanisms underlying cellular organization and responses to environmental stimuli. He collaborates extensively with the Rachubinski and Wozniak laboratories at the University of Alberta. His recent publications reflect a strong focus on systems-level analyses of cellular processes, including gene regulation, chromatin dynamics, and immune responses to infection. Trends in his work include the development of integrative models to predict cellular behavior and the study of organelle dynamics in health and disease. CIHR Scholar AHFMR Scholar Dr. Aitchison has mentored numerous postdoctoral fellows and research scientists, including Fred Mast, Song Li, and Thurston Herricks. His lab has received support from various funding agencies, enabling large-scale proteomic and genomic studies. He also contributes to scientific discourse through editorial roles, as seen in his commentary on MBoC. His laboratory operates at the intersection of experimental and computational biology, developing and applying high-throughput technologies to address fundamental questions in cell biology and infectious disease.