جست‌وجوی استاد و پژوهشگر

Vivian Lee-Kimمشاهده پروفایل

استادیار

• Cardiovascular Genetics
• Vascular Biology
• Regenerative Medicine
• +۳ مورد دیگر

Vivian Lee-Kim is an Assistant Professor in the Department of Pediatrics, Division of Cardiology at The University of Texas Southwestern Medical Center, with a secondary appointment in the Department of Molecular Biology. She is also a member of the Center for Regenerative Science and Medicine. Education B.S. in Biochemistry, University of Washington Ph.D. in Developmental, Regenerative, and Stem Cell Biology, Washington University in St. Louis Postdoctoral Fellow, Brigham and Women's Hospital and Harvard Medical School Research Interests Dr. Lee-Kim's research focuses on the genetic and molecular mechanisms of cardiovascular diseases, particularly thoracic aortic aneurysms and coronary artery disease. She employs genomic approaches, CRISPR-based genome editing, and vascular biology to dissect disease pathways and identify therapeutic targets. Her work bridges basic science with clinical applications in regenerative medicine, investigating coding and noncoding genetic variations that contribute to vascular pathologies. Recent Research Trends Analysis of Dr. Lee-Kim's 13 publications (2012-2024) reveals an evolution from extracellular matrix genetics in aortic aneurysms to cutting-edge multi-omics studies of coronary artery disease. Her recent work (2020-2024) emphasizes endothelial cell programs, CRISPR perturbation screens, and functional genomics to identify novel therapeutic targets, while earlier research (2012-2016) explored mechanisms of aortic dilation and lung injury models. This trajectory demonstrates increasing integration of genomic technologies with vascular pathophysiology. Honors & Awards No specific awards are listed in the available information. Advising and Grants Information regarding student mentorship, grant funding, or research funding sources is not provided in the available text. Labs and Teams Dr. Lee-Kim is an active member of the Center for Regenerative Science and Medicine at UT Southwestern, which fosters interdisciplinary collaboration in tissue engineering, stem cell therapies, and vascular regeneration research.

David J. Andersonمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Neural Circuits
• +۵ مورد دیگر

David J. Anderson is the Seymour Benzer Professor of Biology at the California Institute of Technology (Caltech), serving as Director and Leadership Chair of the Tianqiao and Chrissy Chen Institute for Neuroscience. He is also a long-standing Investigator of the Howard Hughes Medical Institute (HHMI), appointed in 1989. His academic credentials include an A.B. in Biochemical Sciences from Harvard University (1978, summa cum laude) and a Ph.D. in Cell Biology from Rockefeller University (1983), where he trained with Nobel Laureate Günter Blobel. Postdoctoral training followed at Columbia University with Nobel Laureate Richard Axel. Anderson's research centers on the neurobiological basis of emotional behaviors, particularly fear, anxiety, and aggression. His lab employs mice, Drosophila, and the jellyfish Clytia hemisphaerica to dissect neural circuits using optogenetics, chemogenetics, single-cell RNA sequencing, and advanced behavioral analysis. Key discoveries include identifying aggression-controlling neurons in the hypothalamus and fear-processing microcircuits in the amygdala. Recent publications reveal a strong emphasis on decoding aggression circuits through computational modeling of neural dynamics, whole-brain imaging, and cross-species comparisons. His work integrates molecular, cellular, and systems approaches to understand how internal emotional states emerge from neural activity and influence behavior. Major scientific awards include: 2018 Edward M. Scolnick Prize in Neuroscience 2017 New York Academy of Medicine Salmon Award 2016 Perl-UNC Neuroscience Prize 2007 National Academy of Sciences election Multiple named professorships and fellowships As an HHMI Investigator since 1989 and Allen Distinguished Investigator (2010), Anderson has secured substantial research funding. He serves on the Scientific Advisory Board of the Allen Institute for Brain Science and has mentored numerous trainees. His lab develops cutting-edge tools like the Mouse Action Recognition System (MARS) for behavioral analysis. The David Anderson Lab operates as a multidisciplinary hub integrating genetics, neurophysiology, and computational methods. Current collaborations with engineering groups focus on machine vision for behavior quantification, while expanding the Clytia model to investigate primitive internal states in brainless organisms.

Joseph Parkerمشاهده پروفایل

استاد

• Symbiosis
• Evolutionary Biology
• Entomology
• +۴ مورد دیگر

Joseph Parker serves as Professor of Biology and Biological Engineering at the California Institute of Technology (Caltech), where he also directs the Center for Evolutionary Science (CES). Appointed Assistant Professor in 2017, he advanced to full Professor in 2025 following significant contributions to evolutionary symbiosis research. His work centers on the genetic, genomic, and neurobiological mechanisms underlying interspecies interactions, primarily using rove beetles as model organisms to dissect their symbiotic relationships with ants. His educational foundation includes: B.S. from Imperial College London (2001) Ph.D. from University of Cambridge (2005) Parker's research investigates how organisms evolve cross-species interactions through dramatic adaptations in behavior, chemical communication, and neural circuitry. The Parker Lab pioneers rove beetle studies to understand transitions from free-living to symbiotic lifestyles, examining specialized biosynthetic pathways and sensorimotor systems that enable integration into ant colonies. This work bridges evolutionary theory with molecular mechanisms, revealing principles of ecological relationship formation. Recent publications demonstrate interdisciplinary convergence across genomics, neurobiology, and paleontology, with recurring themes in biosynthetic innovation, neural control of interspecies behavior, and evolutionary replay of symbiotic adaptations. Key journals include Cell , Current Biology , and Nature Communications , reflecting integration of molecular, organismal, and macroevolutionary perspectives. His scientific recognition includes: Chen Scholar (2022-2024) Administrative support is provided by Lilian Porter (lilianp@caltech.edu). While specific grant details and student mentorship records aren't documented in the source material, his lab's experimental framework combines genomic sequencing, neuroanatomical analysis, and behavioral assays to address fundamental questions in evolutionary biology. The Parker Lab operates within Caltech's Division of Biology and Biological Engineering, utilizing specialized facilities in Beckman Behavioral Biology (Mail Code: MC 216-76). Current research emphasizes chemical communication systems in beetle-ant symbiosis, with ongoing work on biosynthetic gene clusters and neural substrates of social integration.

Sethu Pitchiayaمشاهده پروفایل

استادیار

• Molecular Biology
• Cancer Research
• Urology
• +۳ مورد دیگر

Sethu Pitchiaya is an Assistant Professor in the Department of Urology at the University of Michigan . His research bridges molecular biology, urologic oncology, and computational biology, focusing on prostate cancer mechanisms and biomolecular condensate dynamics. Department: Urology University: University of Michigan Academic Rank: Assistant Professor Research Interests Pitchiaya's work explores prostate cancer heterogeneity , ERG gene fusion in tumorigenesis, and biomolecular condensates in kidney disease. His studies integrate spatial transcriptomics , single-molecule imaging , and ribonucleoprotein (RNP) biology to uncover novel therapeutic targets. Recent articles highlight trends in phase separation in renal physiology, stress-induced granule formation in male infertility, and zone-specific gene expression in prostate cancer. His collaborations with Arul Chinnaiyan, Nils Walter, and Marcin Cieslik reflect interdisciplinary approaches to understanding cancer biology and cellular stress responses. Labs & Collaborations Active in the Nils Walter Lab and the Arul Chinnaiyan Lab , Pitchiaya contributes to projects involving RNA biology , prostate cancer genomics , and biomolecular condensate research . His work with digital spatial profiling and cell-free systems exemplifies cutting-edge methodologies in molecular diagnostics.

R. Stephanie S Huangمشاهده پروفایل

استاد

• Pharmacogenetics
• Computational Biology
• Cancer Genetics
• +۳ مورد دیگر

R. Stephanie S Huang is a Professor in the Department of Experimental and Clinical Pharmacology at the University of Minnesota, specializing in cancer genetics and computational pharmacology. Her research focuses on pharmacogenomics, non-coding RNAs, and computational approaches for precision oncology. Research Focus Professor Huang leads NIH-funded investigations into: Genetic mechanisms of sexual dimorphism in cancer therapy response AR signaling pathways in prostate cancer Lineage plasticity in treatment-resistant cancers Computational drug discovery pipelines Single-cell transcriptomic analysis of drug responses Publication Trends Recent work demonstrates strong emphasis on computational oncology approaches for prostate cancer, including therapeutic target identification (e.g., NAMPT), metabolic pathway analysis, and integration of single-cell with bulk RNAseq data. Publications frequently appear in high-impact journals including PNAS and Clinical Cancer Research. Grant Leadership Actively leads multiple NIH grants including: Dynamic Digital Tumors for Precision Oncology (PI, 2025) Genetic Mechanisms of Sexual Dimorphism in Cancer (PI, 2024-2026) Cancer Center Support Grant (Co-I, 2024-2029) AR Signaling in Prostate Cancer (Co-I, 2023-2028) Collaboration Network Extensive multi-institutional collaborations with researchers at University of California San Diego, University of Colorado, and NIH-funded consortia.

• Human Molecular Genetics
• Obesity
• Cardiometabolic Phenotypes
• +۳ مورد دیگر

Georgios Dedousis is a Professor of Human Cellular and Molecular Biology at Harokopio University, focusing on Human Molecular Genetics with emphasis on obesity, cardiometabolic phenotypes, and gene-nutrition interactions. He is affiliated with the Laboratory of Biology, Biochemistry, and Physiology of Humans and Microorganisms. Doctoral thesis, Medical School, University of Athens (1995) DEA, University of Technology of Compiegne, France (1990) Degree in Biology, School of Physics and Mathematics, University of Patras (1988) His research spans genetics of metabolic disorders, nutritional genomics, and collaborative networks like the VEGF Consortium. Recent publications highlight genome-wide studies on type 2 diabetes, NAFLD, and coronary artery disease. Fulbright Scholar at Harvard Medical School (2004)

• Diabetic Nephropathy
• Mitochondrial Biology
• Kidney Disease
• +۳ مورد دیگر

Kathryn White is a Researcher at Newcastle University, focusing on diabetic nephropathy, mitochondrial biology, and retinal development. Her work spans cellular ultrastructure analysis, stem cell-derived organoid modeling, and therapeutic approaches for genetic disorders like Joubert syndrome. Collaborated on mitochondrial morphology studies in diabetes and skeletal muscle Developed protocols for retinal organoid differentiation Explored gene therapies for ciliopathies Her scientific contributions include studies on diabetic kidney disease mechanisms, retinal regeneration, and mitochondrial dysfunction. Recent publications highlight her expertise in quantitative 3D imaging and translational therapies. She received the EFSD/Merck travel fellowship for young scientists in 2000. Current research involves collaborations with multidisciplinary teams in nephrology, ophthalmology, and mitochondrial medicine.

• Gene Expression Regulation
• Herpesviridae
• Picornaviridae Infections
• +۱۵ مورد دیگر

Carlos Gorbea, PhD, is a Research Fellow affiliated with the Department of Biochemistry at the University of Utah School of Medicine. His research spans molecular virology, RNA biology, and neuroinflammation. Postdoctoral Fellowship: University of Utah School of Medicine Postdoctoral Training: Pennsylvania State University Doctoral/Master’s Training: Virginia Polytechnic Institute and State University Research Interests: Dr. Gorbea investigates RNA virus infections, focusing on post-transcriptional RNA processing, non-coding RNA in innate immunity, and mechanisms like intracellular proteolysis and cell motility. His work explores links between Gammaherpesvirinae/Picornaviridae infections and neurodegenerative disorders. Publication Trends: Recent studies involve RNA-seq analysis of neuroinflammatory models, emphasizing microglia/macrophage-specific gene markers during viral infections.

Bradley R. Cairnsمشاهده پروفایل

استاد

• Chromatin Remodeling
• Germline Development
• Transcription Regulation
• +۷ مورد دیگر

Bradley R. Cairns, PhD, is Professor and Chair of the Department of Oncological Sciences at the University of Utah School of Medicine, Chief Academic Officer of the Huntsman Cancer Institute (HCI), and holder of the Jon M. Huntsman Presidential Endowed Chair in Cancer Research. His research focuses on chromatin remodeling, germline development, and cancer mechanisms, utilizing zebrafish, yeast, and human models. Dr. Cairns pioneered the purification of chromatin remodeling complexes (SWI/SNF, RSC) and revealed their dysregulation in cancer. Education: PhD in Cell Biology, Stanford University (1996) BS (Honors) in Chemistry, Lewis and Clark College (1987) Postdoctoral training at Harvard Medical School and Stanford University Research Interests: Dr. Cairns investigates how chromatin structure regulates gene expression in germline stem cells and early embryos, with emphasis on totipotency establishment. His lab studies: 1) Mechanisms of nucleosome remodeling by ATP-dependent complexes; 2) Epigenetic poising of developmental genes in sperm; 3) Single-cell dynamics of human spermatogenesis; and 4) DUX transcription factors in embryonic genome activation. Key models include zebrafish embryogenesis and human testis development. Publication Trends: Recent work emphasizes single-cell genomics of human germline development, 3D chromatin architecture in embryogenesis, and p53-mediated regulation in muscular dystrophy. Studies consistently integrate biochemical, genetic, and genomic approaches to dissect chromatin-transcription relationships in development and disease. Awards & Honors: Fellow, Royal Society (2023) American Academy of Arts and Sciences (2017) Howard Hughes Medical Institute Investigator (2000–present) Leukemia Society Fellowship American Cancer Society Fellowship Leadership & Training: Dr. Cairns has mentored 26 graduate students and 12 postdoctoral fellows. He directs the Molecular Biology Graduate Program and co-leads HCI’s Nuclear Control Program. Administrative roles include chairing HCI’s Bioinformatics and Genomics Cores and co-chairing the Commission on Equity, Diversity, and Inclusion. Lab & Collaborations: The Cairns Lab employs biochemical, genomic, and genetic methods to study chromatin dynamics. Key collaborations include the Human Testis Atlas project and studies on FSHD muscular dystrophy. Lab resources include protocols for chromatin profiling and zebrafish embryogenesis.

• Cancer Therapy
• Cancer Cell Biology
• Epigenetics
• +۳ مورد دیگر

Sudhakar Jha is an Associate Professor in the Department of Physiological Sciences at Oklahoma State University's College of Veterinary Medicine. He also serves as a Visiting Principal Investigator at the Cancer Science Institute of Singapore since October 2021. His research focuses on epigenetic mechanisms in cancer development, particularly examining chromatin-remodeling complexes and their role in tumorigenesis. Dr. Jha earned his Ph.D. from Jawaharlal Nehru University in New Delhi, India (2000-2003), followed by postdoctoral training as a Research Fellow (2003-2006) and Research Associate (2006-2021) at the University of Virginia's Department of Biochemistry and Molecular Genetics. Prior to joining Oklahoma State University, he held positions as Junior Principal Investigator (2011-2015) and Principal Investigator (2016-2021) at the Cancer Science Institute of Singapore. Dr. Jha's research primarily investigates how chromatin organization malfunctions lead to cancer development through down-regulation of tumor suppressors and expression of oncogenes. His work focuses on chromatin-remodeling complexes that create epigenetic codes influencing active or repressed chromatin states. His laboratory explores the regulation of these complexes, with particular emphasis on TIP60 and other epigenetic regulators in various cancer types including colorectal cancer, liver cancer, and leukemia. His research has significant implications for developing novel epigenetic therapies targeting cancer stem cells and treatment resistance. Analysis of Dr. Jha's recent publications reveals a strong focus on epigenetic mechanisms in cancer, particularly examining histone modifications, chromatin remodeling, and transcriptional regulation. His work spans multiple cancer types with emphasis on colorectal cancer, liver cancer, and hematological malignancies. A notable theme is the investigation of TIP60 and its interactions with other epigenetic regulators in cancer stemness and metastasis. His research increasingly incorporates advanced techniques including 3D culture models, spatial biology, and functional enhancer profiling to understand cancer heterogeneity. OSHE Safety Award from National University of Singapore, Cancer Science Institute of Singapore (2021) Dr. Jha actively mentors graduate students through PhD Research and Dissertation courses and the Niblack Research Scholars program at Oklahoma State University. He has secured substantial funding from diverse sources including the National Institutes of Health, Oklahoma Center for Adult Stem Cell Research, and Singaporean research councils. His grants focus on epigenetic mechanisms in cancer, chromatin organization, TERT promoter mutations, and therapeutic targeting of epigenetic regulators. Dr. Jha's research program represents a multidisciplinary approach integrating molecular biology, epigenetics, and cancer therapeutics. Dr. Jha maintains active research collaborations between Oklahoma State University and the Cancer Science Institute of Singapore. His laboratory investigates the molecular mechanisms of epigenetic regulators in cancer development and progression, with particular focus on chromatin-remodeling complexes. The research environment fosters interdisciplinary collaboration between cancer biologists, epigeneticists, and clinicians to translate basic discoveries into potential therapeutic approaches for various cancer types.

Lucas Pozzo-Millerمشاهده پروفایل

استاد

• Neuroscience
• Neurodevelopmental Disorders
• Synaptic Plasticity
• +۳ مورد دیگر

Lucas Pozzo-Miller is a Professor at Michigan State University, affiliated with the Neuroscience Program, BioMolecular Science Gateway, Cell & Molecular Biology Program, and Genetics & Genome Sciences Program. His research centers on neurodevelopmental disorders, synaptic plasticity, and molecular neuroscience, with a specialized focus on Rett syndrome pathophysiology and therapeutic interventions. Research interests span multiple domains: Neurodevelopmental Disorders : Mechanisms of Rett syndrome (MECP2 dysfunction), autism spectrum disorders, and dendritic spine pathologies. Synaptic Plasticity : BDNF/TrkB signaling, glutamate receptor trafficking, and structural remodeling of dendritic spines in learning/memory contexts. Molecular Neuroscience : Epigenetic regulation, ion channel dynamics (e.g., TRPC, ASIC1a), and kinase signaling pathways (PKA, ERK) in neuronal function. His recent publications (2020-2025) predominantly investigate Rett syndrome models, emphasizing: (1) MeCP2 gene rescue strategies, (2) dendritic spine restoration via TrkB ligands, (3) hippocampal/cortical circuit dysfunction, and (4) novel therapeutic targets. No awards, grants, or student advisees are documented in available sources.

Jason Raymond Gallantمشاهده پروفایل

دانشیار

• Evolutionary Biology
• Genetics
• Genomics
• +۶ مورد دیگر

Jason Raymond Gallant serves as Associate Professor and Associate Chair in the Department of Integrative Biology at Michigan State University, with additional affiliations in the Genetics & Genome Sciences Program and BioMolecular Science Gateway. His research program investigates the evolutionary and genetic mechanisms underlying novel phenotypic traits in animal communication systems, utilizing mormyrid electric fish as a primary model organism to explore signal diversity, mate choice, and speciation processes. Dr. Gallant's research spans evolutionary biology, genomics, neuroethology, and developmental biology, integrating approaches from behavior, physiology, and population genetics. His work examines how novel communication signals originate and diversify through molecular adaptations, with particular focus on electric organ discharges, reproductive biology, and ion channel evolution in weakly electric fish. This integrative framework enables comprehensive analysis of genotype-phenotype relationships in natural communication systems. Analysis of Dr. Gallant's 15 most recent publications (2018-2025) reveals three dominant research trajectories: (1) molecular mechanisms of electric signal variation involving potassium/sodium channels and gene expression changes, (2) evolutionary adaptations in reproductive biology including sperm flagella loss, and (3) methodological innovations in electric fish genomics using CRISPR/Cas9 editing. His work consistently bridges evolutionary theory with molecular experimentation, demonstrating how convergent phenotypic evolution arises through diverse genetic pathways. No scientific awards were documented in the provided source materials. While specific student mentorship details are absent from the text, Dr. Gallant leads the Electric Fish Laboratory (http://efish.integrativebiology.msu.edu/), which maintains active research programs in electric fish communication. The laboratory's extensive publication record suggests ongoing graduate student supervision and collaborative grant-funded research, though specific funding sources and advisee names were not disclosed in the available information.

• Computational Statistics
• Bioinformatics
• Parallel Computing
• +۳ مورد دیگر

Henrik Bengtsson is a computational biologist and software developer at the University of California San Francisco (UCSF). His work spans parallel computing frameworks in R, genomic data analysis, and statistical methods for biomedical research. Key contributions include the 'future' package for parallel processing in R Developed 'matrixStats' and 'progressr' libraries for computational efficiency Collaborated on cancer genomics projects including glioma and prostate cancer studies His research focuses on: Unified computational frameworks for distributed processing Advanced genomic data normalization techniques Statistical algorithms for tumor progression analysis Development of robust open-source bioinformatics tools Epigenetic reprogramming in cancer evolution Multi-platform data integration for precision medicine

Anne-Lise Børresen-Daleمشاهده پروفایل

استاد

• Molecular Biology
• Breast Cancer
• Genomic Analysis
• +۳ مورد دیگر

Anne-Lise Børresen-Dale is a Professor at the Faculty of Medicine, University of Oslo, specializing in molecular tumor biology and breast cancer research. Her work focuses on genome-wide tumor analysis for personalized treatment strategies and early diagnosis. 1970: MSc in Biochemistry, Norwegian Institute of Technology 1978: PhD in Medical Biochemical Genetics, University of Oslo 1987: Professor in Genetic Technology 1992: Professor in Molecular Tumor Biology Her research spans genomic profiling , epigenetic regulation , and multi-omics integration to characterize breast cancer subtypes and predict clinical outcomes. Key contributions include developing polygenic risk scores and analyzing germline-somatic interactions . Recent publications highlight her role in deep learning pathology scoring , immune checkpoint target identification , and Mendelian randomization studies . She has supervised 36 PhD and 18 MSc students, with ongoing mentorship projects.

Riccardo Panellaمشاهده پروفایل

دانشیار بالینی

• Molecular Biology
• Genetics
• Biomedical Research
• +۵ مورد دیگر

Riccardo Panella is a Clinical Associate Professor at the Clinical Institute within Aalborg University's Faculty of Health Sciences and affiliated with the Center for RNA Medicine . His research focuses on microRNA biology, metabolic homeostasis, and RNA-based therapies. Current Role: Clinical Associate Professor, Aalborg University Key Research Areas: microRNA-22 regulation, lipid metabolism, Duchenne Muscular Dystrophy, antisense oligonucleotides, environmental RNA responses Research Highlights: Dr. Panella investigates microRNA-22's role in metabolic and genetic disorders, including Duchenne Muscular Dystrophy and metabolic dysfunction-associated steatotic liver disease. His work spans RNA regulation , mouse models , and biomarker development . Publication Trends: Recent articles emphasize microRNA-22's impact on lipid homeostasis, immunostimulatory responses to antimiR-22, and environmental stress responses in RNA signatures. Collaborative studies involve metabolic imaging , long non-coding RNAs , and transgenic mouse models . Advising: Supervising Tomasini, S. in a PhD project on microRNA-22 in Duchenne Muscular Dystrophy (2024–2025).